Last update:
Tue Jul 14 09:13:00 MDT 2020
W. S. Sossin and
J. M. Fisher and
R. H. Scheller Sorting within the regulated secretory
pathway occurs in the trans-Golgi
network . . . . . . . . . . . . . . . . 1
T. Nakata and
K. Sobue and
N. Hirokawa Conformational change and localization
of calpactin I complex involved in
exocytosis as revealed by quick-freeze,
deep-etch electron microscopy and
immunocytochemistry . . . . . . . . . . 13
S. J. Gould and
S. Krisans and
G. A. Keller and
S. Subramani Antibodies directed against the
peroxisomal targeting signal of firefly
luciferase recognize multiple mammalian
peroxisomal proteins . . . . . . . . . . 27
J. J. Doherty and
D. G. Kay and
W. H. Lai and
B. I. Posner and
J. J. Bergeron Selective degradation of insulin within
rat liver endosomes . . . . . . . . . . 35
P. W. Marks and
F. R. Maxfield Transient increases in cytosolic free
calcium appear to be required for the
migration of adherent human neutrophils 43
T. Funatsu and
H. Higuchi and
S. Ishiwata Elastic filaments in skeletal muscle
revealed by selective removal of thin
filaments with plasma gelsolin . . . . . 53
T. J. O'Halloran and
S. Ravid and
J. A. Spudich Expression of \bionameDictyostelium
myosin tail segments in
\bionameEscherichia coli: domains
required for assembly and
phosphorylation . . . . . . . . . . . . 63
P. Lamoureux and
V. L. Steel and
C. Regal and
L. Adgate and
R. E. Buxbaum and
S. R. Heidemann Extracellular matrix allows PC12 neurite
elongation in the absence of
microtubules . . . . . . . . . . . . . . 71
C. L. Rieder and
S. P. Alexander Kinetochores are transported poleward
along a single astral microtubule during
chromosome attachment to the spindle in
newt lung cells . . . . . . . . . . . . 81
H. N. Baker and
S. W. Rothwell and
W. A. Grasser and
K. T. Wallis and
D. B. Murphy Copolymerization of two distinct tubulin
isotypes during microtubule assembly in
vitro . . . . . . . . . . . . . . . . . 97
B. K. Haarer and
S. H. Lillie and
A. E. Adams and
V. Magdolen and
W. Bandlow and
S. S. Brown Purification of profilin from
\bionameSaccharomyces cerevisiae and
analysis of profilin-deficient cells . . 105
J. W. Su and
L. G. Tertoolen and
S. W. de Laat and
W. J. Hage and
A. J. Durston Intercellular communication is cell
cycle modulated during early
\bionameXenopus laevis development . . . 115
O. Kellermann and
M. H. Buc-Caron and
P. J. Marie and
D. Lamblin and
F. Jacob An immortalized osteogenic cell line
derived from mouse teratocarcinoma is
able to mineralize in vivo and in vitro 123
M. P. Welch and
G. F. Odland and
R. A. Clark Temporal relationships of F-actin bundle
formation, collagen and fibronectin
matrix assembly, and fibronectin
receptor expression to wound contraction 133
B. R. Bowen and
C. Fennie and
L. A. Lasky The Mel 14 antibody binds to the lectin
domain of the murine peripheral lymph
node homing receptor . . . . . . . . . . 147
R. R. Schleef and
T. J. Podor and
E. Dunne and
J. Mimuro and
D. J. Loskutoff The majority of type 1 plasminogen
activator inhibitor associated with
cultured human endothelial cells is
located under the cells and is
accessible to solution-phase tissue-type
plasminogen activator . . . . . . . . . 155
S. Gloor and
H. Antonicek and
K. J. Sweadner and
S. Pagliusi and
R. Frank and
M. Moos and
M. Schachner The adhesion molecule on glia (AMOG) is
a homologue of the beta subunit of the
Na,K--ATPase . . . . . . . . . . . . . . 165
Y. Hayashi and
B. Haimovich and
A. Reszka and
D. Boettiger and
A. Horwitz Expression and function of chicken
integrin beta 1 subunit and its
cytoplasmic domain mutants in mouse NIH
3T3 cells . . . . . . . . . . . . . . . 175
B. Clément and
B. Segui-Real and
P. Savagner and
H. K. Kleinman and
Y. Yamada Hepatocyte attachment to laminin is
mediated through multiple receptors . . 185
G. Kadmon and
A. Kowitz and
P. Altevogt and
M. Schachner The neural cell adhesion molecule N-CAM
enhances L1-dependent cell--cell
interactions . . . . . . . . . . . . . . 193
G. Kadmon and
A. Kowitz and
P. Altevogt and
M. Schachner Functional cooperation between the
neural adhesion molecules L1 and N-CAM
is carbohydrate dependent . . . . . . . 209
H. Sawada and
H. Konomi and
K. Hirosawa Characterization of the collagen in the
hexagonal lattice of Descemet's
membrane: its relation to type VIII
collagen . . . . . . . . . . . . . . . . 219
M. F. Smith and
B. D. Athey and
S. P. Williams and
J. P. Langmore Radial density distribution of
chromatin: evidence that chromatin
fibers have solid centers . . . . . . . 245
G. Ching and
E. Wang Characterization of two populations of
statin and the relationship of their
syntheses to the state of cell
proliferation . . . . . . . . . . . . . 255
R. S. Dwivedi and
A. V. Yeldandi and
V. Subbarao and
P. Feigelson and
A. K. Roy and
J. K. Reddy and
M. S. Rao Androgen regulated expression of the
alpha 2u-globulin gene in pancreatic
hepatocytes of rat . . . . . . . . . . . 263
B. Risek and
S. Guthrie and
N. Kumar and
N. B. Gilula Modulation of gap junction transcript
and protein expression during pregnancy
in the rat . . . . . . . . . . . . . . . 269
S. Q. Jing and
T. Spencer and
K. Miller and
C. Hopkins and
I. S. Trowbridge Role of the human transferrin receptor
cytoplasmic domain in endocytosis:
localization of a specific signal
sequence for internalization . . . . . . 283
K. M. Cadigan and
D. M. Spillane and
T. Y. Chang Isolation and characterization of
Chinese hamster ovary cell mutants
defective in intracellular low density
lipoprotein-cholesterol trafficking . . 295
D. Brada and
D. Kerjaschki and
J. Roth Cell type-specific post-Golgi apparatus
localization of a ``resident''
endoplasmic reticulum glycoprotein,
glucosidase II . . . . . . . . . . . . . 309
E. M. Prence and
J. M. Dong and
G. G. Sahagian Modulation of the transport of a
lysosomal enzyme by PDGF . . . . . . . . 319
R. L. Pisoni and
T. L. Acker and
K. M. Lisowski and
R. M. Lemons and
J. G. Thoene A cysteine-specific lysosomal transport
system provides a major route for the
delivery of thiol to human fibroblast
lysosomes: possible role in supporting
lysosomal proteolysis . . . . . . . . . 327
E. J. Hughson and
C. R. Hopkins Endocytic pathways in polarized Caco-2
cells: identification of an endosomal
compartment accessible from both apical
and basolateral surfaces . . . . . . . . 337
W. J. Nelson and
E. M. Shore and
A. Z. Wang and
R. W. Hammerton Identification of a
membrane-cytoskeletal complex containing
the cell adhesion molecule uvomorulin
(E-cadherin), ankyrin, and fodrin in
Madin--Darby canine kidney epithelial
cells . . . . . . . . . . . . . . . . . 349
M. C. Sanders and
Y. L. Wang Exogenous nucleation sites fail to
induce detectable polymerization of
actin in living cells . . . . . . . . . 359
Y. Fukui and
A. De Lozanne and
J. A. Spudich Structure and function of the
cytoskeleton of a \bionameDictyostelium
myosin-defective mutant . . . . . . . . 367
G. Piperno and
Z. Ramanis and
E. F. Smith and
W. S. Sale Three distinct inner dynein arms in
\bionameChlamydomonas flagella:
molecular composition and location in
the axoneme . . . . . . . . . . . . . . 379
T. S. Hays and
E. D. Salmon Poleward force at the kinetochore in
metaphase depends on the number of
kinetochore microtubules . . . . . . . . 391
C. Klotz and
M. C. Dabauvalle and
M. Paintrand and
T. Weber and
M. Bornens and
E. Karsenti Parthenogenesis in \bionameXenopus eggs
requires centrosomal integrity . . . . . 405
H. Masuda and
T. Hirano and
M. Yanagida and
W. Z. Cande In vitro reactivation of spindle
elongation in fission yeast nuc2 mutant
cells . . . . . . . . . . . . . . . . . 417
M. J. Fietz and
R. B. Presland and
G. E. Rogers The cDNA-deduced amino acid sequence for
trichohyalin, a differentiation marker
in the hair follicle, contains a 23
amino acid repeat . . . . . . . . . . . 427
R. A. Nixon and
I. Fischer and
S. E. Lewis Synthesis, axonal transport, and
turnover of the high molecular weight
microtubule-associated protein MAP 1A in
mouse retinal ganglion cells: tubulin
and MAP 1A display distinct transport
kinetics . . . . . . . . . . . . . . . . 437
F. Torri-Tarelli and
A. Villa and
F. Valtorta and
P. De Camilli and
P. Greengard and
B. Ceccarelli Redistribution of synaptophysin and
synapsin I during
alpha-latrotoxin-induced release of
neurotransmitter at the neuromuscular
junction . . . . . . . . . . . . . . . . 449
P. C. Begovac and
B. D. Shur Cell surface galactosyltransferase
mediates the initiation of neurite
outgrowth from PC12 cells on laminin . . 461
D. D. Mikol and
J. R. Gulcher and
K. Stefansson The oligodendrocyte-myelin glycoprotein
belongs to a distinct family of proteins
and contains the HNK-1 carbohydrate . . 471
S. Dedhar and
R. Saulnier Alterations in integrin receptor
expression on chemically transformed
human cells: specific enhancement of
laminin and collagen receptor complexes 481
F. Bellot and
W. Moolenaar and
R. Kris and
B. Mirakhur and
I. Verlaan and
A. Ullrich and
J. Schlessinger and
S. Felder High-affinity epidermal growth factor
binding is specifically reduced by a
monoclonal antibody, and appears
necessary for early responses . . . . . 491
B. B. Olwin and
S. D. Hauschka Fibroblast growth factor receptor levels
decrease during chick embryogenesis . . 503
R. Tsuboi and
Y. Sato and
D. B. Rifkin Correlation of cell migration, cell
invasion, receptor number, proteinase
production, and basic fibroblast growth
factor levels in endothelial cells . . . 511
C. Guidry and
S. Hohn and
M. Hook Endothelial cells secrete a factor that
promotes fibroblast contraction of
hydrated collagen gels . . . . . . . . . 519
G. A. Zimmerman and
T. M. McIntyre and
M. Mehra and
S. M. Prescott Endothelial cell-associated
platelet-activating factor: a novel
mechanism for signaling intercellular
adhesion . . . . . . . . . . . . . . . . 529
D. D. Newmeyer and
D. J. Forbes An N-ethylmaleimide-sensitive cytosolic
factor necessary for nuclear protein
import: requirement in signal-mediated
binding to the nuclear pore . . . . . . 547
L. W. Jiang and
M. Schindler Nucleocytoplasmic transport is enhanced
concomitant with nuclear accumulation of
epidermal growth factor (EGF) binding
activity in both 3T3-1 and EGF receptor
reconstituted NR-6 fibroblasts . . . . . 559
D. C. He and
J. A. Nickerson and
S. Penman Core filaments of the nuclear matrix . . 569
M. Martins-Green and
M. J. Bissell Localization of 9E3/CEF-4 in avian
tissues: expression is absent in Rous
sarcoma virus-induced tumors but is
stimulated by injury . . . . . . . . . . 581
R. L. Gimlich and
N. M. Kumar and
N. B. Gilula Differential regulation of the levels of
three gap junction mRNAs in
\bionameXenopus embryos . . . . . . . . 597
K. Kadomatsu and
R. P. Huang and
T. Suganuma and
F. Murata and
T. Muramatsu A retinoic acid responsive gene MK found
in the teratocarcinoma system is
expressed in spatially and temporally
controlled manner during mouse
embryogenesis . . . . . . . . . . . . . 607
T. K. Tang and
Z. Qin and
T. Leto and
V. T. Marchesi and
E. J. Benz Heterogeneity of mRNA and protein
products arising from the protein 4.1
gene in erythroid and nonerythroid
tissues . . . . . . . . . . . . . . . . 617
J. E. Bergmann and
P. J. Fusco The G protein of vesicular stomatitis
virus has free access into and egress
from the smooth endoplasmic reticulum of
UT-1 cells . . . . . . . . . . . . . . . 625
K. G. Rothberg and
Y. S. Ying and
J. F. Kolhouse and
B. A. Kamen and
R. G. Anderson The glycophospholipid-linked folate
receptor internalizes folate without
entering the clathrin-coated pit
endocytic pathway . . . . . . . . . . . 637
T. Tsukamoto and
S. Yokota and
Y. Fujiki Isolation and characterization of
Chinese hamster ovary cell mutants
defective in assembly of peroxisomes . . 651
B. Pytowski and
F. R. Maxfield and
J. Michl Fc and C3bi receptors and the
differentiation antigen BH2-Ag are
randomly distributed in the plasma
membrane of locomoting neutrophils . . . 661
L. Bomblies and
E. Biegelmann and
V. Döring and
G. Gerisch and
H. Krafft-Czepa and
A. A. Noegel and
M. Schleicher and
B. M. Humbel Membrane-enclosed crystals in
\bionameDictyostelium discoideum cells,
consisting of developmentally regulated
proteins with sequence similarities to
known esterases . . . . . . . . . . . . 669
A. Shariff and
E. J. Luna \bionameDictyostelium discoideum plasma
membranes contain an actin-nucleating
activity that requires ponticulin, an
integral membrane glycoprotein . . . . . 681
G. F. Gauthier Differential distribution of myosin
isoforms among the myofibrils of
individual developing muscle fibers . . 693
J. M. Miller and
W. Wang and
R. Balczon and
W. L. Dentler Ciliary microtubule capping structures
contain a mammalian kinetochore antigen 703
R. L. Rotundo Nucleus-specific translation and
assembly of acetylcholinesterase in
multinucleated muscle cells . . . . . . 715
D. F. Cutler and
L. P. Cramer Sorting during transport to the surface
of PC12 cells: divergence of synaptic
vesicle and secretory granule proteins 721
C. M. Ely and
K. M. Oddie and
J. S. Litz and
A. J. Rossomando and
S. B. Kanner and
T. W. Sturgill and
S. J. Parsons A 42-kD tyrosine kinase substrate linked
to chromaffin cell secretion exhibits an
associated MAP kinase activity and is
highly related to a 42-kD
mitogen-stimulated protein in
fibroblasts . . . . . . . . . . . . . . 731
D. R. Borchelt and
M. Scott and
A. Taraboulos and
N. Stahl and
S. B. Prusiner Scrapie and cellular prion proteins
differ in their kinetics of synthesis
and topology in cultured cells . . . . . 743
A. M. Gonzalez and
M. Buscaglia and
M. Ong and
A. Baird Distribution of basic fibroblast growth
factor in the $ 18$-day rat fetus:
localization in the basement membranes
of diverse tissues . . . . . . . . . . . 753
O. Saksela and
D. B. Rifkin Release of basic fibroblast growth
factor-heparan sulfate complexes from
endothelial cells by plasminogen
activator-mediated proteolytic activity 767
J. B. McCarthy and
A. P. Skubitz and
Z. Qi and
X. Y. Yi and
D. J. Mickelson and
D. J. Klein and
L. T. Furcht RGD-independent cell adhesion to the
carboxy-terminal heparin-binding
fragment of fibronectin involves
heparin-dependent and -independent
activities . . . . . . . . . . . . . . . 777
C. T. Basson and
W. J. Knowles and
L. Bell and
S. M. Albelda and
V. Castronovo and
L. A. Liotta and
J. A. Madri Spatiotemporal segregation of
endothelial cell integrin and
nonintegrin extracellular matrix-binding
proteins during adhesion events . . . . 789
H. Larjava and
J. Peltonen and
S. K. Akiyama and
S. S. Yamada and
H. R. Gralnick and
J. Uitto and
K. M. Yamada Novel function for beta 1 integrins in
keratinocyte cell--cell interactions . . 803
A. K. Hall and
R. Nelson and
U. Rutishauser Binding properties of
detergent-solubilized NCAM . . . . . . . 817
J. C. Schittny and
P. D. Yurchenco Terminal short arm domains of basement
membrane laminin are critical for its
self-assembly . . . . . . . . . . . . . 825
J. L. Guan and
J. E. Trevithick and
R. O. Hynes Retroviral expression of alternatively
spliced forms of rat fibronectin . . . . 833
P. Simon-Assmann and
F. Bouziges and
J. N. Freund and
F. Perrin-Schmitt and
M. Kedinger Type IV collagen mRNA accumulates in the
mesenchymal compartment at early stages
of murine developing intestine . . . . . 849
R. J. Feeney and
G. W. Zieve Nuclear exchange of the U1 and U2
snRNP-specific proteins . . . . . . . . 871
R. Reichelt and
A. Holzenburg and
E. L. Buhle and
M. Jarnik and
A. Engel and
U. Aebi Correlation between structure and mass
distribution of the nuclear pore complex
and of distinct pore complex components 883
N. L. Kedersha and
M. C. Miquel and
D. Bittner and
L. H. Rome Vaults. II. Ribonucleoprotein structures
are highly conserved among higher and
lower eukaryotes . . . . . . . . . . . . 895
M. M. Heck and
A. C. Spradling Multiple replication origins are used
during \bionameDrosophila chorion gene
amplification . . . . . . . . . . . . . 903
A. L. Tyner and
R. Godbout and
R. S. Compton and
S. M. Tilghman The ontogeny of alpha-fetoprotein gene
expression in the mouse gastrointestinal
tract . . . . . . . . . . . . . . . . . 915
T. J. Brennan and
D. G. Edmondson and
E. N. Olson Aberrant regulation of MyoD1 contributes
to the partially defective myogenic
phenotype of BC3H1 cells . . . . . . . . 929
S. Dübel and
H. C. Schaller Terminal differentiation of ectodermal
epithelial stem cells of Hydra can occur
in G2 without requiring mitosis or S
phase . . . . . . . . . . . . . . . . . 939
B. W. Wattenberg and
R. R. Hiebsch and
L. W. LeCureux and
M. P. White Identification of a 25-kD protein from
yeast cytosol that operates in a
prefusion step of vesicular transport
between compartments of the Golgi . . . 947
N. Pfanner and
B. S. Glick and
S. R. Arden and
J. E. Rothman Fatty acylation promotes fusion of
transport vesicles with Golgi cisternae 955
A. Hille and
A. Waheed and
K. von Figura Assembly of the ligand-binding
conformation of Mr 46,000 mannose
$6$-phosphate-specific receptor takes
place before reaching the Golgi complex 963
T. Wileman and
G. R. Carson and
M. Concino and
A. Ahmed and
C. Terhorst The gamma and epsilon subunits of the
CD3 complex inhibit pre-Golgi
degradation of newly synthesized T cell
antigen receptors . . . . . . . . . . . 973
E. Schaerer and
F. Verrey and
L. Racine and
C. Tallichet and
M. Reinhardt and
J. P. Kraehenbuhl Polarized transport of the polymeric
immunoglobulin receptor in transfected
rabbit mammary epithelial cells . . . . 987
R. G. Paterson and
R. A. Lamb Conversion of a class II integral
membrane protein into a soluble and
efficiently secreted protein: multiple
intracellular and extracellular
oligomeric and conformational forms . . 999
D. M. Ward and
D. P. Hackenyos and
J. Kaplan Fusion of sequentially internalized
vesicles in alveolar macrophages . . . . 1013
C. F. Roff and
C. W. Hall and
A. R. Robbins Recovery of function in Chinese hamster
ovary cell mutants with
temperature-sensitive defects in
vacuolar acidification . . . . . . . . . 1023
G. Alvarez de Toledo and
J. M. Fernandez Patch-clamp measurements reveal
multimodal distribution of granule sizes
in rat mast cells . . . . . . . . . . . 1033
J. D. Ashcom and
S. E. Tiller and
K. Dickerson and
J. L. Cravens and
W. S. Argraves and
D. K. Strickland The human alpha $2$-macroglobulin
receptor: identification of a 420-kD
cell surface glycoprotein specific for
the activated conformation of alpha
$2$-macroglobulin . . . . . . . . . . . 1041
W. P. Jiang and
R. A. Gottlieb and
W. J. Lennarz and
W. H. Kinsey Phorbol ester treatment stimulates
tyrosine phosphorylation of a sea urchin
egg cortex protein . . . . . . . . . . . 1049
G. P. Richardson and
S. Bartolami and
I. J. Russell Identification of a 275-kD protein
associated with the apical surfaces of
sensory hair cells in the avian inner
ear . . . . . . . . . . . . . . . . . . 1055
L. Cassimeris and
H. McNeill and
S. H. Zigmond Chemoattractant-stimulated
polymorphonuclear leukocytes contain two
populations of actin filaments that
differ in their spatial distributions
and relative stabilities . . . . . . . . 1067
T. K. Rosiere and
J. A. Marrs and
G. B. Bouck A 39-kD plasma membrane protein (IP39)
is an anchor for the unusual membrane
skeleton of Euglena gracilis . . . . . . 1077
L. G. Cao and
Y. L. Wang Mechanism of the formation of
contractile ring in dividing cultured
animal cells. I. Recruitment of
preexisting actin filaments into the
cleavage furrow . . . . . . . . . . . . 1089
T. Ueda and
T. Nakagaki and
T. Yamada Dynamic organization of ATP and
birefringent fibrils during free
locomotion and galvanotaxis in the
plasmodium of Physarum polycephalum . . 1097
J. K. Han and
R. Nuccitelli Inositol 1,4,5-trisphosphate-induced
calcium release in the organelle layers
of the stratified, intact egg of
\bionameXenopus laevis . . . . . . . . . 1103
D. J. Flanders and
D. J. Rawlins and
P. J. Shaw and
C. W. Lloyd Nucleus-associated microtubules help
determine the division plane of plant
epidermal cells: avoidance of four-way
junctions and the role of cell geometry 1111
B. Buendia and
M. H. Bré and
G. Griffiths and
E. Karsenti Cytoskeletal control of centrioles
movement during the establishment of
polarity in Madin--Darby canine kidney
cells . . . . . . . . . . . . . . . . . 1123
K. Collins and
J. R. Sellers and
P. Matsudaira Calmodulin dissociation regulates brush
border myosin I (110-kD-calmodulin)
mechanochemical activity in vitro . . . 1137
R. Eichner and
M. Kahn Differential extraction of keratin
subunits and filaments from normal human
epidermis . . . . . . . . . . . . . . . 1149
T. Schultheiss and
Z. X. Lin and
M. H. Lu and
J. Murray and
D. A. Fischman and
K. Weber and
T. Masaki and
M. Imamura and
H. Holtzer Differential distribution of subsets of
myofibrillar proteins in cardiac
nonstriated and striated myofibrils . . 1159
A. O. Jorgensen and
W. Arnold and
A. C. Shen and
S. H. Yuan and
M. Gaver and
K. P. Campbell Identification of novel proteins unique
to either transverse tubules (TS28) or
the sarcolemma (SL50) in rabbit skeletal
muscle . . . . . . . . . . . . . . . . . 1173
S. Yuan and
W. Arnold and
A. O. Jorgensen Biogenesis of transverse tubules:
immunocytochemical localization of a
transverse tubular protein (TS28) and a
sarcolemmal protein (SL50) in rabbit
skeletal muscle developing in situ . . . 1187
M. Hatzfeld and
K. Weber The coiled coil of in vitro assembled
keratin filaments is a heterodimer of
type I and II keratins: use of
site-specific mutagenesis and
recombinant protein expression . . . . . 1199
B. C. Tilly and
L. G. Tertoolen and
R. Remorie and
A. Ladoux and
I. Verlaan and
S. W. de Laat and
W. H. Moolenaar Histamine as a growth factor and
chemoattractant for human carcinoma and
melanoma cells: action through
Ca2(+)-mobilizing H1 receptors . . . . . 1211
K. Hyrc and
B. Rose The action of v-src on gap junctional
permeability is modulated by pH . . . . 1217
S. M. Albelda and
P. D. Oliver and
L. H. Romer and
C. A. Buck EndoCAM: a novel endothelial cell--cell
adhesion molecule . . . . . . . . . . . 1227
F. Matsuzaki and
R. M. M\`ege and
S. H. Jaffe and
D. R. Friedlander and
W. J. Gallin and
J. I. Goldberg and
B. A. Cunningham and
G. M. Edelman cDNAs of cell adhesion molecules of
different specificity induce changes in
cell shape and border formation in
cultured S180 cells . . . . . . . . . . 1239
J. L. Bixby and
R. Zhang Purified N-cadherin is a potent
substrate for the rapid induction of
neurite outgrowth . . . . . . . . . . . 1253
B. Schlosshauer and
K. H. Herzog Neurothelin: an inducible cell surface
glycoprotein of blood-brain
barrier-specific endothelial cells and
distinct neurons . . . . . . . . . . . . 1261
K. S. O'Shea and
J. S. Rheinheimer and
V. M. Dixit Deposition and role of thrombospondin in
the histogenesis of the cerebellar
cortex . . . . . . . . . . . . . . . . . 1275
M. Baumert and
K. Takei and
J. Hartinger and
P. M. Burger and
G. Fischer von Mollard and
P. R. Maycox and
P. De Camilli and
R. Jahn P29: a novel tyrosine-phosphorylated
membrane protein present in small clear
vesicles of neurons and endocrine cells 1285
A. M. Tolkovsky and
A. E. Walker and
R. D. Murrell and
H. S. Suidan Ca$^{2+}$ transients are not required as
signals for long-term neurite outgrowth
from cultured sympathetic neurons . . . 1295
P. Caroni and
P. Grandes Nerve sprouting in innervated adult
skeletal muscle induced by exposure to
elevated levels of insulin-like growth
factors . . . . . . . . . . . . . . . . 1307
K. Goslin and
G. Banker Rapid changes in the distribution of
GAP-43 correlate with the expression of
neuronal polarity during normal
development and under experimental
conditions . . . . . . . . . . . . . . . 1319
D. H. Damon and
P. A. D'Amore and
J. A. Wagner Nerve growth factor and fibroblast
growth factor regulate neurite outgrowth
and gene expression in PC12 cells via
both protein kinase C- and
cAMP-independent mechanisms . . . . . . 1333
E. Kordeli and
J. Davis and
B. Trapp and
V. Bennett An isoform of ankyrin is localized at
nodes of Ranvier in myelinated axons of
central and peripheral nerves . . . . . 1341
J. B. Davis and
P. Stroobant Platelet-derived growth factors and
fibroblast growth factors are mitogens
for rat Schwann cells . . . . . . . . . 1353
R. M. Lyons and
L. E. Gentry and
A. F. Purchio and
H. L. Moses Mechanism of activation of latent
recombinant transforming growth factor
beta 1 by plasmin . . . . . . . . . . . 1361
P. G. Strauss and
E. I. Closs and
J. Schmidt and
V. Erfle Gene expression during osteogenic
differentiation in mandibular condyles
in vitro . . . . . . . . . . . . . . . . 1369
R. Quarto and
B. Dozin and
C. Tacchetti and
G. Campanile and
C. Malfatto and
R. Cancedda In vitro development of hypertrophic
chondrocytes starting from selected
clones of dedifferentiated cells . . . . 1379
W. G. Carter and
E. A. Wayner and
T. S. Bouchard and
P. Kaur The role of integrins alpha 2 beta 1 and
alpha 3 beta 1 in cell--cell and
cell-substrate adhesion of human
epidermal cells . . . . . . . . . . . . 1387
C. H. Streuli and
M. J. Bissell Expression of extracellular matrix
components is regulated by substratum 1405
H. Sano and
R. Forough and
J. A. Maier and
J. P. Case and
A. Jackson and
K. Engleka and
T. Maciag and
R. L. Wilder Detection of high levels of heparin
binding growth factor-1 (acidic
fibroblast growth factor) in
inflammatory arthritic joints . . . . . 1417
S. Aznavoorian and
M. L. Stracke and
H. Krutzsch and
E. Schiffmann and
L. A. Liotta Signal transduction for chemotaxis and
haptotaxis by matrix molecules in tumor
cells . . . . . . . . . . . . . . . . . 1427
P. B. Armstrong and
M. T. Armstrong An instructive role for the interstitial
matrix in tissue patterning: tissue
segregation and intercellular invasion 1439
J. M. Fitch and
D. E. Birk and
C. Linsenmayer and
T. F. Linsenmayer The spatial organization of Descemet's
membrane-associated type IV collagen in
the avian cornea . . . . . . . . . . . . 1457
C. A. Cooke and
R. L. Bernat and
W. C. Earnshaw CENP-B: a major human centromere protein
located beneath the kinetochore . . . . 1475
L. A. Beck and
T. J. Hosick and
M. Sinensky Isoprenylation is required for the
processing of the lamin A precursor . . 1489
D. L. Wiest and
J. K. Burkhardt and
S. Hester and
M. Hortsch and
D. I. Meyer and
Y. Argon Membrane biogenesis during B cell
differentiation: most endoplasmic
reticulum proteins are expressed
coordinately . . . . . . . . . . . . . . 1501
I. McMorrow and
W. E. Souter and
G. Plopper and
B. Burke Identification of a Golgi-associated
protein that undergoes mitosis dependent
phosphorylation and relocation . . . . . 1513
P. Lemansky and
S. H. Fatemi and
B. Gorican and
S. Meyale and
R. Rossero and
A. M. Tartakoff Dynamics and longevity of the
glycolipid-anchored membrane protein,
Thy-1 . . . . . . . . . . . . . . . . . 1525
A. Le Bivic and
Y. Sambuy and
K. Mostov and
E. Rodriguez-Boulan Vectorial targeting of an endogenous
apical membrane sialoglycoprotein and
uvomorulin in MDCK cells . . . . . . . . 1533
A. M. Honegger and
A. Schmidt and
A. Ullrich and
J. Schlessinger Separate endocytic pathways of
kinase-defective and -active EGF
receptor mutants expressed in same cells 1541
T. J. Sun and
P. J. Van Haastert and
P. N. Devreotes Surface cAMP receptors mediate multiple
responses during development in
\bionameDictyostelium: evidenced by
antisense mutagenesis . . . . . . . . . 1549
M. E. Jaconi and
D. P. Lew and
J. L. Carpentier and
K. E. Magnusson and
M. Sjögren and
O. Stendahl Cytosolic free calcium elevation
mediates the phagosome-lysosome fusion
during phagocytosis in human neutrophils 1555
W. M. Kühtreiber and
L. F. Jaffe Detection of extracellular calcium
gradients with a calcium-specific
vibrating electrode . . . . . . . . . . 1565
Y. S. Choi and
R. Sehgal and
P. McCrea and
B. Gumbiner A cadherin-like protein in eggs and
cleaving embryos of \bionameXenopus
laevis is expressed in oocytes in
response to progesterone . . . . . . . . 1575
S. Yamashita and
J. L. Maller Identification of an activator required
for elevation of maturation-promoting
factor (MPF) activity by gamma--S--ATP 1583
J. E. Speksnijder and
C. Sardet and
L. F. Jaffe The activation wave of calcium in the
ascidian egg and its role in ooplasmic
segregation . . . . . . . . . . . . . . 1589
R. S. Kochanski and
G. G. Borisy Mode of centriole duplication and
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A. A. Hyman and
T. J. Mitchison Modulation of microtubule stability by
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I. M. Hagan and
P. N. Riddle and
J. S. Hyams Intramitotic controls in the fission
yeast \bionameSchizosaccharomyces pombe:
the effect of cell size on spindle
length and the timing of mitotic events 1617
J. E. Rickard and
T. E. Kreis Identification of a novel
nucleotide-sensitive microtubule-binding
protein in HeLa cells . . . . . . . . . 1623
G. H. Nuckolls and
C. E. Turner and
K. Burridge Functional studies of the domains of
talin . . . . . . . . . . . . . . . . . 1635
L. Hou and
K. Luby-Phelps and
F. Lanni Brownian motion of inert tracer
macromolecules in polymerized and
spontaneously bundled mixtures of actin
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A. Tsuru and
N. Nakamura and
E. Takayama and
Y. Suzuki and
K. Hirayoshi and
K. Nagata Regulation of the expression of vimentin
gene during the differentiation of mouse
myeloid leukemia cells . . . . . . . . . 1655
P. Jin and
M. Rahm and
L. Claesson-Welsh and
C. H. Heldin and
T. Sejersen Expression of PDGF A-chain and
beta-receptor genes during rat myoblast
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D. Nandan and
E. P. Clarke and
E. H. Ball and
B. D. Sanwal Ethyl-3,4-dihydroxybenzoate inhibits
myoblast differentiation: evidence for
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D. N. Cooper and
S. H. Barondes Evidence for export of a muscle lectin
from cytosol to extracellular matrix and
for a novel secretory mechanism . . . . 1681
L. Clift-O'Grady and
A. D. Linstedt and
A. W. Lowe and
E. Grote and
R. B. Kelly Biogenesis of synaptic vesicle-like
structures in a pheochromocytoma cell
line PC-12 . . . . . . . . . . . . . . . 1693
H. L. Paulson and
T. Claudio Temperature-sensitive expression of
all--Torpedo and Torpedo-rat hybrid AChR
in mammalian muscle cells . . . . . . . 1705
S. M. Staugaitis and
P. R. Smith and
D. R. Colman Expression of myelin basic protein
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B. Key and
R. A. Akeson Olfactory neurons express a unique
glycosylated form of the neural cell
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R. L. Heimark and
M. Degner and
S. M. Schwartz Identification of a Ca2(+)-dependent
cell--cell adhesion molecule in
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W. Risau and
B. Engelhardt and
H. Wekerle Immune function of the blood-brain
barrier: incomplete presentation of
protein (auto-)antigens by rat brain
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M. B. Rogers and
S. C. Watkins and
L. J. Gudas Gene expression in visceral endoderm: a
comparison of mutant and wild-type F9
embryonal carcinoma cell differentiation 1767
A. Kurtz and
F. Vogel and
K. Funa and
C. H. Heldin and
R. Grosse Developmental regulation of
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K. A. Roth and
J. M. Hertz and
J. I. Gordon Mapping enteroendocrine cell populations
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D. E. Ingber and
D. Prusty and
J. V. Frangioni and
E. J. Cragoe and
C. Lechene and
M. A. Schwartz Control of intracellular pH and growth
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T. Darrib\`ere and
K. Guida and
H. Larjava and
K. E. Johnson and
K. M. Yamada and
J. P. Thiery and
J. C. Boucaut In vivo analyses of integrin beta 1
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T. Elkins and
M. Hortsch and
A. J. Bieber and
P. M. Snow and
C. S. Goodman Drosophila fasciclin I is a novel
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C. Boone and
S. S. Sommer and
A. Hensel and
H. Bussey Yeast KRE genes provide evidence for a
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C. S. Downes and
S. R. Musk and
J. V. Watson and
R. T. Johnson Caffeine overcomes a restriction point
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C. M. Starr and
M. D'Onofrio and
M. K. Park and
J. A. Hanover Primary sequence and heterologous
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Q. Chen and
L. M. Lauzon and
A. E. DeRocher and
E. Vierling Accumulation, stability, and
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J. P. Vogel and
L. M. Misra and
M. D. Rose Loss of BiP/GRP78 function blocks
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J. Nair and
H. Müller and
M. Peterson and
P. Novick Sec2 protein contains a coiled-coil
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B. Singer and
H. Riezman Detection of an intermediate compartment
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W. A. Dunn Studies on the mechanisms of autophagy:
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W. A. Dunn Studies on the mechanisms of autophagy:
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R. Furukawa and
J. E. Wampler and
M. Fechheimer Cytoplasmic pH of \bionameDictyostelium
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G. Jung and
J. A. Hammer Generation and characterization of
\bionameDictyostelium cells deficient in
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F. S. Southwick and
C. L. Young The actin released from profilin--actin
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G. P. Downey and
C. K. Chan and
S. Trudel and
S. Grinstein Actin assembly in electropermeabilized
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T. Howard and
C. Chaponnier and
H. Yin and
T. Stossel Gelsolin-actin interaction and actin
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K. Arikawa and
J. L. Hicks and
D. S. Williams Identification of actin filaments in the
rhabdomeral microvilli of
\bionameDrosophila photoreceptors . . . 1993
E. Fyrberg and
M. Kelly and
E. Ball and
C. Fyrberg and
M. C. Reedy Molecular genetics of \bionameDrosophila
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R. K. Meyer and
U. Aebi Bundling of actin filaments by
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G. Sluder and
F. J. Miller and
R. Cole and
C. L. Rieder Protein synthesis and the cell cycle:
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eggs is not under translational control 2025
D. L. Gard and
S. Hafezi and
T. Zhang and
S. J. Doxsey Centrosome duplication continues in
cycloheximide-treated \bionameXenopus
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M. Ewert and
B. D. Shivers and
H. Lüddens and
H. Möhler and
P. H. Seeburg Subunit selectivity and epitope
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against the GABAA/benzodiazepine
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M. Velez and
K. F. Barald and
D. Axelrod Rotational diffusion of acetylcholine
receptors on cultured rat myotubes . . . 2049
Q. Chen and
R. Sealock and
H. B. Peng A protein homologous to the Torpedo
postsynaptic 58K protein is present at
the myotendinous junction . . . . . . . 2061
E. DiCicco-Bloom and
E. Townes-Anderson and
I. B. Black Neuroblast mitosis in dissociated
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H. Haltmeier and
H. Rohrer Distinct and different effects of the
oncogenes v-myc and v-src on avian
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P. V. Sarthy and
M. Fu Localization of laminin B1 mRNA in
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P. M. Persechini and
J. D. Young and
W. Almers Membrane channel formation by the
lymphocyte pore-forming protein:
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A. Taraboulos and
D. Serban and
S. B. Prusiner Scrapie prion proteins accumulate in the
cytoplasm of persistently infected
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M. Yeager and
K. A. Dryden and
N. H. Olson and
H. B. Greenberg and
T. S. Baker Three-dimensional structure of rhesus
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A. Sonnenberg and
C. J. Linders and
P. W. Modderman and
C. H. Damsky and
M. Aumailley and
R. Timpl Integrin recognition of different
cell-binding fragments of laminin (P1,
E3, E8) and evidence that alpha 6 beta 1
but not alpha 6 beta 4 functions as a
major receptor for fragment E8 . . . . . 2145
M. R. Campanero and
R. Pulido and
M. A. Ursa and
M. Rodríguez-Moya and
M. O. de Landázuri and
F. Sánchez-Madrid An alternative leukocyte homotypic
adhesion mechanism,
LFA-1/ICAM-$1$-independent, triggered
through the human VLA-4 integrin . . . . 2157
L. M. Shaw and
J. M. Messier and
A. M. Mercurio The activation dependent adhesion of
macrophages to laminin involves
cytoskeletal anchoring and
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integrin . . . . . . . . . . . . . . . . 2167
D. E. Hall and
L. F. Reichardt and
E. Crowley and
B. Holley and
H. Moezzi and
A. Sonnenberg and
C. H. Damsky The alpha 1/beta 1 and alpha 6/beta 1
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attachment to distinct sites on laminin 2175
S. Dedhar and
V. Gray Isolation of a novel integrin receptor
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Association of a novel beta $1$-related
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M. E. Joyce and
A. B. Roberts and
M. B. Sporn and
M. E. Bolander Transforming growth factor-beta and the
initiation of chondrogenesis and
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G. B. Silberstein and
P. Strickland and
S. Coleman and
C. W. Daniel Epithelium-dependent extracellular
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S. R. Watson and
Y. Imai and
C. Fennie and
J. S. Geoffroy and
S. D. Rosen and
L. A. Lasky A homing receptor--IgG chimera as a
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C. M. Feldherr and
D. Akin The permeability of the nuclear envelope
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J. Laitinen and
L. Sistonen and
K. Alitalo and
E. Hölttä c-Ha-rasVal 12 oncogene-transformed
NIH-3T3 fibroblasts display more
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S. Ahle and
E. Ungewickell Auxilin, a newly identified
clathrin-associated protein in coated
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M. K. Spriggs and
P. L. Collins Intracellular processing and transport
of NH2-terminally truncated forms of a
hemagglutinin-neuraminidase type II
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M. E. Groesch and
H. Ruohola and
R. Bacon and
G. Rossi and
S. Ferro-Novick Isolation of a functional vesicular
intermediate that mediates ER to Golgi
transport in yeast . . . . . . . . . . . 45
D. F. Singer and
J. J. Linderman The relationship between antigen
concentration, antigen internalization,
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C. P. Blobel and
D. G. Myles and
P. Primakoff and
J. M. White Proteolytic processing of a protein
involved in sperm-egg fusion correlates
with acquisition of fertilization
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T. Morimoto and
S. Ogihara and
H. Takisawa Anchorage of secretion-competent dense
granules on the plasma membrane of
bovine platelets in the absence of
secretory stimulation . . . . . . . . . 79
D. Troschel and
M. Müller Development of a cell-free system to
study the membrane assembly of
photosynthetic proteins of Rhodobacter
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J. Vandekerckhove and
G. Bauw and
K. Vancompernolle and
B. Honoré and
J. Celis Comparative two-dimensional gel analysis
and microsequencing identifies gelsolin
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downregulated markers of transformed
human fibroblast and epithelial cells 95
A. Fernandez and
D. L. Brautigan and
M. Mumby and
N. J. Lamb Protein phosphatase type-1, not type-2A,
modulates actin microfilament integrity
and myosin light chain phosphorylation
in living nonmuscle cells . . . . . . . 103
D. R. Webster and
J. Wehland and
K. Weber and
G. G. Borisy Detyrosination of alpha tubulin does not
stabilize microtubules in vivo . . . . . 113
S. S. Lim and
K. J. Edson and
P. C. Letourneau and
G. G. Borisy A test of microtubule translocation
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A. E. Adams and
D. I. Johnson and
R. M. Longnecker and
B. F. Sloat and
J. R. Pringle CDC42 and CDC43, two additional genes
involved in budding and the
establishment of cell polarity in the
yeast \bionameSaccharomyces cerevisiae 131
D. I. Johnson and
J. R. Pringle Molecular characterization of CDC42, a
\bionameSaccharomyces cerevisiae gene
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P. A. Coulombe and
E. Fuchs Elucidating the early stages of keratin
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D. H. Zhang and
D. A. Callaham and
P. K. Hepler Regulation of anaphase chromosome motion
in \bionameTradescantia stamen hair
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J. P. Kao and
J. M. Alderton and
R. Y. Tsien and
R. A. Steinhardt Active involvement of Ca$^{2+}$ in
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S. K. Nigam and
T. Towers Subcellular distribution of
calcium-binding proteins and a
calcium--ATPase in canine pancreas . . . 197
R. Bischoff Cell cycle commitment of rat muscle
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A. da Cunha and
L. Vitkovi\'c Regulation of immunoreactive GAP-43
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A. W. Stoker and
C. Hatier and
M. J. Bissell The embryonic environment strongly
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D. D. Schlaepfer and
H. T. Haigler Expression of annexins as a function of
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R. A. Majack and
M. W. Majesky and
L. V. Goodman Role of PDGF--A expression in the
control of vascular smooth muscle cell
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factor-beta . . . . . . . . . . . . . . 239
D. M. Peters and
L. M. Portz and
J. Fullenwider and
D. F. Mosher Co-assembly of plasma and cellular
fibronectins into fibrils in human
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T. Tschan and
I. Höerler and
Y. Houze and
K. H. Winterhalter and
C. Richter and
P. Bruckner Resting chondrocytes in culture survive
without growth factors, but are
sensitive to toxic oxygen metabolites 257
M. K. Chelberg and
J. B. McCarthy and
A. P. Skubitz and
L. T. Furcht and
E. C. Tsilibary Characterization of a synthetic peptide
from type IV collagen that promotes
melanoma cell adhesion, spreading, and
motility . . . . . . . . . . . . . . . . 261
A. P. Otte and
D. Roy and
M. Siemerink and
C. H. Koster and
F. Hochstenbach and
A. Timmermans and
A. J. Durston Characterization of a maternal type VI
collagen in \bionameXenopus embryos
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M. O. Soyer-Gobillard and
M. L. Géraud and
D. Coulaud and
M. Barray and
B. Théveny and
B. Révet and
E. Delain Location of B- and Z--DNA in the
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A. K. Hopper and
H. M. Traglia and
R. W. Dunst The yeast RNA1 gene product necessary
for RNA processing is located in the
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W. J. Hong and
D. Doyle Molecular dissection of the NH2-terminal
signal/anchor sequence of rat dipeptidyl
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J. Tooze and
M. Hollinshead and
T. Ludwig and
K. Howell and
B. Hoflack and
H. Kern In exocrine pancreas, the basolateral
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R. K. Pathak and
M. Yokode and
R. E. Hammer and
S. L. Hofmann and
M. S. Brown and
J. L. Goldstein and
R. G. Anderson Tissue-specific sorting of the human LDL
receptor in polarized epithelia of
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L. A. Valls and
J. R. Winther and
T. H. Stevens Yeast carboxypeptidase Y vacuolar
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N. Dean and
H. R. Pelham Recycling of proteins from the Golgi
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W. I. Lencer and
A. S. Verkman and
M. A. Arnaout and
D. A. Ausiello and
D. Brown Endocytic vesicles from renal papilla
which retrieve the vasopressin-sensitive
water channel do not contain a
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B. Kabakoff and
W. J. Lennarz Inhibition of glycoprotein processing
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development of the sea urchin embryo . . 391
A. M. da Silva and
C. Klein A rapid posttranslational myristylation
of a 68-kD protein in \bionameD.
discoideum . . . . . . . . . . . . . . . 401
A. Ceriotti and
A. Colman Trimer formation determines the rate of
influenza virus haemagglutinin transport
in the early stages of secretion in
\bionameXenopus oocytes . . . . . . . . 409
B. W. Wattenberg Glycolipid and glycoprotein transport
through the Golgi complex are similar
biochemically and kinetically.
Reconstitution of glycolipid transport
in a cell free system . . . . . . . . . 421
M. Koval and
R. E. Pagano Sorting of an internalized plasma
membrane lipid between recycling and
degradative pathways in normal and
Niemann--Pick, type A fibroblasts . . . 429
S. M. Hayden and
J. S. Wolenski and
M. S. Mooseker Binding of brush border myosin I to
phospholipid vesicles . . . . . . . . . 443
D. M. Warshaw and
J. M. Desrosiers and
S. S. Work and
K. M. Trybus Smooth muscle myosin cross-bridge
interactions modulate actin filament
sliding velocity in vitro . . . . . . . 453
D. H. Schwyter and
S. J. Kron and
Y. Y. Toyoshima and
J. A. Spudich and
E. Reisler Subtilisin cleavage of actin inhibits in
vitro sliding movement of actin
filaments over myosin . . . . . . . . . 465
V. M. Fowler Tropomodulin: a cytoskeletal protein
that binds to the end of erythrocyte
tropomyosin and inhibits tropomyosin
binding to actin . . . . . . . . . . . . 471
J. E. Fox and
C. D. Austin and
J. K. Boyles and
P. K. Steffen Role of the membrane skeleton in
preventing the shedding of
procoagulant-rich microvesicles from the
platelet plasma membrane . . . . . . . . 483
P. W. Baas and
M. M. Black Individual microtubules in the axon
consist of domains that differ in both
composition and stability . . . . . . . 495
C. Nislow and
C. Sellitto and
R. Kuriyama and
J. R. McIntosh A monoclonal antibody to a mitotic
microtubule-associated protein blocks
mitotic progression . . . . . . . . . . 511
N. Grandin and
M. Charbonneau Cycling of intracellular pH during cell
division of \bionameXenopus embryos is a
cytoplasmic activity depending on
protein synthesis and phosphorylation 523
R. S. Freeman and
J. P. Kanki and
S. M. Ballantyne and
K. M. Pickham and
D. J. Donoghue Effects of the v-mos oncogene on
\bionameXenopus development: meiotic
induction in oocytes and mitotic arrest
in cleaving embryos . . . . . . . . . . 533
A. H. Osmani and
S. A. Osmani and
N. R. Morris The molecular cloning and identification
of a gene product specifically required
for nuclear movement in Aspergillus
nidulans . . . . . . . . . . . . . . . . 543
A. J. Sarria and
S. K. Nordeen and
R. M. Evans Regulated expression of vimentin cDNA in
cells in the presence and absence of a
preexisting vimentin filament network 553
R. Moll and
D. L. Schiller and
W. W. Franke Identification of protein IT of the
intestinal cytoskeleton as a novel type
I cytokeratin with unusual properties
and expression patterns . . . . . . . . 567
A. Cartaud and
M. A. Ludosky and
J. C. Courvalin and
J. Cartaud A protein antigenically related to
nuclear lamin B mediates the association
of intermediate filaments with
desmosomes . . . . . . . . . . . . . . . 581
G. I. Fishman and
D. C. Spray and
L. A. Leinwand Molecular characterization and
functional expression of the human
cardiac gap junction channel . . . . . . 589
M. Sokabe and
F. Sachs The structure and dynamics of
patch-clamped membranes: a study using
differential interference contrast light
microscopy . . . . . . . . . . . . . . . 599
C. Ortenzi and
C. Miceli and
R. A. Bradshaw and
P. Luporini Identification and initial
characterization of an autocrine
pheromone receptor in the protozoan
ciliate Euplotes raikovi . . . . . . . . 607
T. Satoh and
C. A. Ross and
A. Villa and
S. Supattapone and
T. Pozzan and
S. H. Snyder and
J. Meldolesi The inositol 1,4,5,-trisphosphate
receptor in cerebellar Purkinje cells:
quantitative immunogold labeling reveals
concentration in an ER subcompartment 615
C. A. Dyer and
J. A. Benjamins Glycolipids and transmembrane signaling:
antibodies to galactocerebroside cause
an influx of calcium in oligodendrocytes 625
L. E. Lillien and
M. Sendtner and
M. C. Raff Extracellular matrix-associated
molecules collaborate with ciliary
neurotrophic factor to induce type-2
astrocyte development . . . . . . . . . 635
S. Sheela and
V. M. Riccardi and
N. Ratner Angiogenic and invasive properties of
neurofibroma Schwann cells . . . . . . . 645
S. Rotzler and
H. R. Brenner Metabolic stabilization of acetylcholine
receptors in vertebrate neuromuscular
junction by muscle activity . . . . . . 655
V. Pohl and
P. P. Roger and
D. Christophe and
G. Pattyn and
G. Vassart and
J. E. Dumont Differentiation expression during
proliferative activity induced through
different pathways: in situ
hybridization study of thyroglobulin
gene expression in thyroid epithelial
cells . . . . . . . . . . . . . . . . . 663
R. Roubin and
H. Deagostini-Bazin and
M. R. Hirsch and
C. Goridis Modulation of NCAM expression by
transforming growth factor-beta, serum,
and autocrine factors . . . . . . . . . 673
A. L. Prieto and
F. S. Jones and
B. A. Cunningham and
K. L. Crossin and
G. M. Edelman Localization during development of
alternatively spliced forms of
cytotactin mRNA by in situ hybridization 685
F. J. Fogerty and
S. K. Akiyama and
K. M. Yamada and
D. F. Mosher Inhibition of binding of fibronectin to
matrix assembly sites by anti-integrin
(alpha 5 beta 1) antibodies . . . . . . 699
M. J. Ignatius and
T. H. Large and
M. Houde and
J. W. Tawil and
A. Barton and
F. Esch and
S. Carbonetto and
L. F. Reichardt Molecular cloning of the rat integrin
alpha $1$-subunit: a receptor for
laminin and collagen . . . . . . . . . . 709
C. A. Otey and
F. M. Pavalko and
K. Burridge An interaction between alpha-actinin and
the beta 1 integrin subunit in vitro . . 721
E. Y. Yang and
H. L. Moses Transforming growth factor beta
$1$-induced changes in cell migration,
proliferation, and angiogenesis in the
chicken chorioallantoic membrane . . . . 731
M. S. Pepper and
D. Belin and
R. Montesano and
L. Orci and
J. D. Vassalli Transforming growth factor-beta 1
modulates basic fibroblast growth
factor-induced proteolytic and
angiogenic properties of endothelial
cells in vitro . . . . . . . . . . . . . 743
Y. Sato and
R. Tsuboi and
R. Lyons and
H. Moses and
D. B. Rifkin Characterization of the activation of
latent TGF-beta by co-cultures of
endothelial cells and pericytes or
smooth muscle cells: a self-regulating
system . . . . . . . . . . . . . . . . . 757
G. Taraboletti and
D. Roberts and
L. A. Liotta and
R. Giavazzi Platelet thrombospondin modulates
endothelial cell adhesion, motility, and
growth: a potential angiogenesis
regulatory factor . . . . . . . . . . . 765
I. Cornil and
R. S. Kerbel and
J. W. Dennis Tumor cell surface beta $1$-$4$-linked
galactose binds to lectin(s) on
microvascular endothelial cells and
contributes to organ colonization . . . 773
A. Estreicher and
J. Mühlhauser and
J. L. Carpentier and
L. Orci and
J. D. Vassalli The receptor for urokinase type
plasminogen activator polarizes
expression of the protease to the
leading edge of migrating monocytes and
promotes degradation of enzyme inhibitor
complexes . . . . . . . . . . . . . . . 783
B. D. Athey and
M. F. Smith and
D. A. Rankert and
S. P. Williams and
J. P. Langmore The diameters of frozen-hydrated
chromatin fibers increase with DNA
linker length: evidence in support of
variable diameter models for chromatin 795
S. A. Adam and
R. S. Marr and
L. Gerace Nuclear protein import in permeabilized
mammalian cells requires soluble
cytoplasmic factors . . . . . . . . . . 807
D. Pauli and
C. H. Tonka and
A. Tissieres and
A. P. Arrigo Tissue-specific expression of the heat
shock protein HSP27 during
\bionameDrosophila melanogaster
development . . . . . . . . . . . . . . 817
L. M. Hendershot Immunoglobulin heavy chain and binding
protein complexes are dissociated in
vivo by light chain addition . . . . . . 829
M. S. Marks and
J. S. Blum and
P. Cresswell Invariant chain trimers are sequestered
in the rough endoplasmic reticulum in
the absence of association with HLA
class II antigens . . . . . . . . . . . 839
A. M. de Silva and
W. E. Balch and
A. Helenius Quality control in the endoplasmic
reticulum: folding and misfolding of
vesicular stomatitis virus G protein in
cells and in vitro . . . . . . . . . . . 857
H. Garoff and
D. Huylebroeck and
A. Robinson and
U. Tillman and
P. Liljeström The signal sequence of the p62 protein
of Semliki Forest virus is involved in
initiation but not in completing chain
translocation . . . . . . . . . . . . . 867
C. K. Raymond and
P. J. O'Hara and
G. Eichinger and
J. H. Rothman and
T. H. Stevens Molecular analysis of the yeast VPS3
gene and the role of its product in
vacuolar protein sorting and vacuolar
segregation during the cell cycle . . . 877
N. W. Chege and
S. R. Pfeffer Compartmentation of the Golgi complex:
brefeldin--A distinguishes trans-Golgi
cisternae from the trans-Golgi network 893
B. H. Satir and
C. Srisomsap and
M. Reichman and
R. B. Marchase Parafusin, an exocytic-sensitive
phosphoprotein, is the primary acceptor
for the glucosylphosphotransferase in
Paramecium tetraurelia and rat liver . . 901
M. Aridor and
L. M. Traub and
R. Sagi-Eisenberg Exocytosis in mast cells by basic
secretagogues: evidence for direct
activation of GTP-binding proteins . . . 909
A. Koffer and
P. E. Tatham and
B. D. Gomperts Changes in the state of actin during the
exocytotic reaction of permeabilized rat
mast cells . . . . . . . . . . . . . . . 919
I. Tabas and
S. Lim and
X. X. Xu and
F. R. Maxfield Endocytosed beta--VLDL and LDL are
delivered to different intracellular
vesicles in mouse peritoneal macrophages 929
J. Kopitz and
G. O. Kisen and
P. B. Gordon and
P. Bohley and
P. O. Seglen Nonselective autophagy of cytosolic
enzymes by isolated rat hepatocytes . . 941
M. A. Williams and
M. Fukuda Accumulation of membrane glycoproteins
in lysosomes requires a tyrosine residue
at a particular position in the
cytoplasmic tail . . . . . . . . . . . . 955
S. J. McConnell and
L. C. Stewart and
A. Talin and
M. P. Yaffe Temperature-sensitive yeast mutants
defective in mitochondrial inheritance 967
W. van 't Hof and
G. van Meer Generation of lipid polarity in
intestinal epithelial (Caco-2) cells:
sphingolipid synthesis in the Golgi
complex and sorting before vesicular
traffic to the plasma membrane . . . . . 977
A. Wandinger-Ness and
M. K. Bennett and
C. Antony and
K. Simons Distinct transport vesicles mediate the
delivery of plasma membrane proteins to
the apical and basolateral domains of
MDCK cells . . . . . . . . . . . . . . . 987
H. F. Paterson and
A. J. Self and
M. D. Garrett and
I. Just and
K. Aktories and
A. Hall Microinjection of recombinant p21rho
induces rapid changes in cell morphology 1001
H. D. Hoyle and
E. C. Raff Two \bionameDrosophila beta tubulin
isoforms are not functionally equivalent 1009
N. Hirokawa and
R. Sato-Yoshitake and
T. Yoshida and
T. Kawashima Brain dynein (MAP1C) localizes on both
anterogradely and retrogradely
transported membranous organelles in
vivo . . . . . . . . . . . . . . . . . . 1027
J. H. Hayden and
S. S. Bowser and
C. L. Rieder Kinetochores capture astral microtubules
during chromosome attachment to the
mitotic spindle: direct visualization in
live newt lung cells . . . . . . . . . . 1039
J. R. Glass and
L. Gerace Lamins A and C bind and assemble at the
surface of mitotic chromosomes . . . . . 1047
C. E. Turner and
J. R. Glenney and
K. Burridge Paxillin: a new vinculin-binding protein
present in focal adhesions . . . . . . . 1059
M. V. de Arruda and
S. Watson and
C. S. Lin and
J. Leavitt and
P. Matsudaira Fimbrin is a homologue of the
cytoplasmic phosphoprotein plastin and
has domains homologous with calmodulin
and actin gelation proteins . . . . . . 1069
K. Furuhashi and
S. Hatano Control of actin filament length by
phosphorylation of fragmin-actin complex 1081
J. B. Gorlin and
R. Yamin and
S. Egan and
M. Stewart and
T. P. Stossel and
D. J. Kwiatkowski and
J. H. Hartwig Human endothelial actin-binding protein
(ABP-280, nonmuscle filamin): a
molecular leaf spring . . . . . . . . . 1089
M. O. Shoemaker and
W. Lau and
R. L. Shattuck and
A. P. Kwiatkowski and
P. E. Matrisian and
L. Guerra-Santos and
E. Wilson and
T. J. Lukas and
L. J. Van Eldik and
D. M. Watterson Use of DNA sequence and mutant analyses
and antisense oligodeoxynucleotides to
examine the molecular basis of nonmuscle
myosin light chain kinase
autoinhibition, calmodulin recognition,
and activity . . . . . . . . . . . . . . 1107
J. W. Grant and
M. B. Taubman and
S. L. Church and
R. L. Johnson and
B. Nadal-Ginard Mammalian nonsarcomeric myosin
regulatory light chains are encoded by
two differentially regulated and linked
genes . . . . . . . . . . . . . . . . . 1127
D. Wessels and
D. R. Soll Myosin II heavy chain null mutant of
\bionameDictyostelium exhibits defective
intracellular particle movement . . . . 1137
J. B. Miller Myogenic programs of mouse muscle cell
lines: expression of myosin heavy chain
isoforms, MyoD1, and myogenin . . . . . 1149
R. M. Nitkin and
T. C. Rothschild Agrin-induced reorganization of
extracellular matrix components on
cultured myotubes: relationship to AChR
aggregation . . . . . . . . . . . . . . 1161
G. C. Owens and
C. J. Boyd and
R. P. Bunge and
J. L. Salzer Expression of recombinant
myelin-associated glycoprotein in
primary Schwann cells promotes the
initial investment of axons by
myelinating Schwann cells . . . . . . . 1171
R. Armstrong and
V. L. Friedrich and
K. V. Holmes and
M. Dubois-Dalcq In vitro analysis of the oligodendrocyte
lineage in mice during demyelination and
remyelination . . . . . . . . . . . . . 1183
M. Abe and
R. G. Oshima A single human keratin 18 gene is
expressed in diverse epithelial cells of
transgenic mice . . . . . . . . . . . . 1197
J. Yu and
M. Manabe and
X. R. Wu and
C. Xu and
B. Surya and
T. T. Sun Uroplakin I: a 27-kD protein associated
with the asymmetric unit membrane of
mammalian urothelium . . . . . . . . . . 1207
F. G. Pluthero and
M. Shreeve and
D. Eskinazi and
H. van der Gaag and
K. S. Huang and
J. D. Hulmes and
M. Blum and
A. A. Axelrad Purification of an inhibitor of
erythroid progenitor cell cycling and
antagonist to interleukin 3 from mouse
marrow cell supernatants and its
identification as cytosolic superoxide
dismutase . . . . . . . . . . . . . . . 1217
Y. Imai and
D. D. True and
M. S. Singer and
S. D. Rosen Direct demonstration of the lectin
activity of gp90MEL, a lymphocyte homing
receptor . . . . . . . . . . . . . . . . 1225
R. H. Kramer and
Y. F. Cheng and
R. Clyman Human microvascular endothelial cells
use beta 1 and beta 3 integrin receptor
complexes to attach to laminin . . . . . 1233
M. Korhonen and
J. Ylänne and
L. Laitinen and
I. Virtanen The alpha $1$-alpha 6 subunits of
integrins are characteristically
expressed in distinct segments of
developing and adult human nephron . . . 1245
E. Schnabel and
J. M. Anderson and
M. G. Farquhar The tight junction protein ZO-1 is
concentrated along slit diaphragms of
the glomerular epithelium . . . . . . . 1255
L. Sorokin and
A. Sonnenberg and
M. Aumailley and
R. Timpl and
P. Ekblom Recognition of the laminin E8
cell-binding site by an integrin
possessing the alpha 6 subunit is
essential for epithelial polarization in
developing kidney tubules . . . . . . . 1265
D. A. Brake and
C. Debouck and
G. Biesecker Identification of an Arg--Gly--Asp (RGD)
cell adhesion site in human
immunodeficiency virus type 1
transactivation protein, tat . . . . . . 1275
D. Seiffert and
N. N. Wagner and
D. J. Loskutoff Serum-derived vitronectin influences the
pericellular distribution of type 1
plasminogen activator inhibitor . . . . 1283
A. I. de Agostini and
S. C. Watkins and
H. S. Slayter and
H. Youssoufian and
R. D. Rosenberg Localization of anticoagulantly active
heparan sulfate proteoglycans in
vascular endothelium: antithrombin
binding on cultured endothelial cells
and perfused rat aorta . . . . . . . . . 1293
H. K. Väänänen and
E. K. Karhukorpi and
K. Sundquist and
B. Wallmark and
I. Roininen and
T. Hentunen and
J. Tuukkanen and
P. Lakkakorpi Evidence for the presence of a proton
pump of the vacuolar H(+)-ATPase type in
the ruffled borders of osteoclasts . . . 1305
E. I. Closs and
A. B. Murray and
J. Schmidt and
A. Schön and
V. Erfle and
P. G. Strauss c-fos expression precedes osteogenic
differentiation of cartilage cells in
vitro . . . . . . . . . . . . . . . . . 1313
Y. H. Yu and
D. D. Sabatini and
G. Kreibich Antiribophorin antibodies inhibit the
targeting to the ER membrane of
ribosomes containing nascent secretory
polypeptides . . . . . . . . . . . . . . 1335
S. C. Stirzaker and
D. Poncet and
G. W. Both Sequences in rotavirus glycoprotein VP7
that mediate delayed translocation and
retention of the protein in the
endoplasmic reticulum . . . . . . . . . 1343
A. Le Bivic and
A. Quaroni and
B. Nichols and
E. Rodriguez-Boulan Biogenetic pathways of plasma membrane
proteins in Caco-2, a human intestinal
epithelial cell line . . . . . . . . . . 1351
M. Zanetti and
L. Litteri and
R. Gennaro and
H. Horstmann and
D. Romeo Bactenecins, defense polypeptides of
bovine neutrophils, are generated from
precursor molecules stored in the large
granules . . . . . . . . . . . . . . . . 1363
I. Hanukoglu and
B. S. Suh and
S. Himmelhoch and
A. Amsterdam Induction and mitochondrial localization
of cytochrome P450scc system enzymes in
normal and transformed ovarian granulosa
cells . . . . . . . . . . . . . . . . . 1373
J. J. Neefjes and
T. Hengeveld and
O. Tol and
H. L. Ploegh Intracellular interactions of
transferrin and its receptor during
biosynthesis . . . . . . . . . . . . . . 1383
N. T. Ktistakis and
D. Thomas and
M. G. Roth Characteristics of the tyrosine
recognition signal for internalization
of transmembrane surface glycoproteins 1393
Y. I. Henis and
Z. Katzir and
M. A. Shia and
H. F. Lodish Oligomeric structure of the human
asialoglycoprotein receptor: nature and
stoichiometry of mutual complexes
containing H1 and H2 polypeptides
assessed by fluorescence photobleaching
recovery . . . . . . . . . . . . . . . . 1409
S. L. Acton and
F. M. Brodsky Predominance of clathrin light chain LCb
correlates with the presence of a
regulated secretory pathway . . . . . . 1419
Y. Audigier and
L. Journot and
C. Pantaloni and
J. Bockaert The carboxy-terminal domain of Gs alpha
is necessary for anchorage of the
activated form in the plasma membrane 1427
L. A. Silveira and
D. H. Wong and
F. R. Masiarz and
R. Schekman Yeast clathrin has a distinctive light
chain that is important for cell growth 1437
S. Gehrung and
M. Snyder The SPA2 gene of \bionameSaccharomyces
cerevisiae is important for
pheromone-induced morphogenesis and
efficient mating . . . . . . . . . . . . 1451
G. E. Lyons and
M. Ontell and
R. Cox and
D. Sassoon and
M. Buckingham The expression of myosin genes in
developing skeletal muscle in the mouse
embryo . . . . . . . . . . . . . . . . . 1465
M. Brink and
G. Gerisch and
G. Isenberg and
A. A. Noegel and
J. E. Segall and
E. Wallraff and
M. Schleicher A \bionameDictyostelium mutant lacking
an F-actin cross-linking protein, the
120-kD gelation factor . . . . . . . . . 1477
C. Simerly and
R. Balczon and
B. R. Brinkley and
G. Schatten Microinjected centromere [corrected]
kinetochore antibodies interfere with
chromosome movement in meiotic and
mitotic mouse oocytes . . . . . . . . . 1491
T. P. Spurck and
O. G. Stonington and
J. A. Snyder and
J. D. Pickett-Heaps and
A. Bajer and
J. Mole-Bajer UV microbeam irradiations of the mitotic
spindle. II. Spindle fiber dynamics and
force production . . . . . . . . . . . . 1505
R. L. Bernat and
G. G. Borisy and
N. F. Rothfield and
W. C. Earnshaw Injection of anticentromere antibodies
in interphase disrupts events required
for chromosome movement at mitosis . . . 1519
H. J. Worman and
C. D. Evans and
G. Blobel The lamin B receptor of the nuclear
envelope inner membrane: a polytopic
protein with eight potential
transmembrane domains . . . . . . . . . 1535
M. J. Monteiro and
P. N. Hoffman and
J. D. Gearhart and
D. W. Cleveland Expression of NF--L in both neuronal and
nonneuronal cells of transgenic mice:
increased neurofilament density in axons
without affecting caliber . . . . . . . 1543
J. C. Deloulme and
T. Janet and
D. Au and
D. R. Storm and
M. Sensenbrenner and
J. Baudier Neuromodulin (GAP43): a neuronal protein
kinase C substrate is also present in
0-2A glial cell lineage.
Characterization of neuromodulin in
secondary cultures of oligodendrocytes
and comparison with the neuronal antigen 1559
N. Bataillé and
T. Helser and
H. M. Fried Cytoplasmic transport of ribosomal
subunits microinjected into the
\bionameXenopus laevis oocyte nucleus: a
generalized, facilitated process . . . . 1571
E. C. Tsilibary and
L. A. Reger and
A. M. Vogel and
G. G. Koliakos and
S. S. Anderson and
A. S. Charonis and
J. N. Alegre and
L. T. Furcht Identification of a multifunctional,
cell-binding peptide sequence from the
a1(NC1) of type IV collagen . . . . . . 1583
R. N. Tamura and
C. Rozzo and
L. Starr and
J. Chambers and
L. F. Reichardt and
H. M. Cooper and
V. Quaranta Epithelial integrin alpha 6 beta 4:
complete primary structure of alpha 6
and variant forms of beta 4 . . . . . . 1593
G. R. Hunnicutt and
M. G. Kosfiszer and
W. J. Snell Cell body and flagellar agglutinins in
\bionameChlamydomonas reinhardtii: the
cell body plasma membrane is a reservoir
for agglutinins whose migration to the
flagella is regulated by a functional
barrier . . . . . . . . . . . . . . . . 1605
D. F. Kucik and
E. L. Elson and
M. P. Sheetz Cell migration does not produce membrane
flow . . . . . . . . . . . . . . . . . . 1617
Z. Yablonka-Reuveni and
T. M. Balestreri and
D. F. Bowen-Pope Regulation of proliferation and
differentiation of myoblasts derived
from adult mouse skeletal muscle by
specific isoforms of PDGF . . . . . . . 1623
S. C. Ho and
J. L. Wang and
M. Schindler Carbohydrate binding activities of
Bradyrhizobium japonicum. I.
Saccharide-specific inhibition of
homotypic and heterotypic adhesion . . . 1631
S. C. Ho and
M. Schindler and
J. L. Wang Carbohydrate binding activities of
Bradyrhizobium japonicum. II. Isolation
and characterization of a
galactose-specific lectin . . . . . . . 1639
M. Ozawa and
R. Kemler Correct proteolytic cleavage is required
for the cell adhesive function of
uvomorulin . . . . . . . . . . . . . . . 1645
R. Flaumenhaft and
D. Moscatelli and
D. B. Rifkin Heparin and heparan sulfate increase the
radius of diffusion and action of basic
fibroblast growth factor . . . . . . . . 1651
L. K. Opresko and
H. S. Wiley Functional reconstitutional of the human
epidermal growth factor receptor system
in \bionameXenopus oocytes . . . . . . . 1661
J. Felez and
L. A. Miles and
J. Plescia and
E. F. Plow Regulation of plasminogen receptor
expression on human monocytes and
monocytoid cell lines . . . . . . . . . 1673
J. R. Sanes and
E. Engvall and
R. Butkowski and
D. D. Hunter Molecular heterogeneity of basal
laminae: isoforms of laminin and
collagen IV at the neuromuscular
junction and elsewhere . . . . . . . . . 1685
C. E. Bandtlow and
M. Meyer and
D. Lindholm and
M. Spranger and
R. Heumann and
H. Thoenen Regional and cellular codistribution of
interleukin 1 beta and nerve growth
factor mRNA in the adult rat brain:
possible relationship to the regulation
of nerve growth factor synthesis . . . . 1701
M. Sato and
M. K. Sardana and
W. A. Grasser and
V. M. Garsky and
J. M. Murray and
R. J. Gould Echistatin is a potent inhibitor of bone
resorption in culture . . . . . . . . . 1713
M. W. Clark and
M. L. Yip and
J. Campbell and
J. Abelson SSB-1 of the yeast \bionameSaccharomyces
cerevisiae is a nucleolar-specific,
silver-binding protein that is
associated with the snR10 and snR11
small nuclear RNAs . . . . . . . . . . . 1741
M. Roberge and
J. Th'ng and
J. Hamaguchi and
E. M. Bradbury The topoisomerase II inhibitor VM-26
induces marked changes in histone H1
kinase activity, histones H1 and H3
phosphorylation, and chromosome
condensation in G2 phase and mitotic BHK
cells . . . . . . . . . . . . . . . . . 1753
C. Baitinger and
J. Alderton and
M. Poenie and
H. Schulman and
R. A. Steinhardt Multifunctional
Ca$^{2+}$/calmodulin-dependent protein
kinase is necessary for nuclear envelope
breakdown . . . . . . . . . . . . . . . 1763
R. B. Mandell and
C. M. Feldherr Identification of two HSP70-related
\bionameXenopus oocyte proteins that are
capable of recycling across the nuclear
envelope . . . . . . . . . . . . . . . . 1775
Z. F. Zakeri and
W. J. Welch and
D. J. Wolgemuth Characterization and inducibility of hsp
70 proteins in the male mouse germ line 1785
K. Römisch and
J. Webb and
K. Lingelbach and
H. Gausepohl and
B. Dobberstein The 54-kD protein of signal recognition
particle contains a methionine-rich RNA
binding domain . . . . . . . . . . . . . 1793
R. Gabathuler and
S. Kvist The endoplasmic reticulum retention
signal of the E3/19K protein of
adenovirus type 2 consists of three
separate amino acid segments at the
carboxy terminus . . . . . . . . . . . . 1803
B. D. Beaumelle and
A. Gibson and
C. R. Hopkins Isolation and preliminary
characterization of the major membrane
boundaries of the endocytic pathway in
lymphocytes . . . . . . . . . . . . . . 1811
D. J. Schnell and
G. Blobel and
D. Pain The chloroplast import receptor is an
integral membrane protein of chloroplast
envelope contact sites . . . . . . . . . 1825
B. M. Phelps and
D. E. Koppel and
P. Primakoff and
D. G. Myles Evidence that proteolysis of the surface
is an initial step in the mechanism of
formation of sperm cell surface domains 1839
R. R. Dubreuil and
T. J. Byers and
C. T. Stewart and
D. P. Kiehart A beta-spectrin isoform from
\bionameDrosophila (beta H) is similar
in size to vertebrate dystrophin . . . . 1849
L. H. Bookbinder and
G. W. Moy and
V. D. Vacquier Identification of sea urchin sperm
adenylate cyclase . . . . . . . . . . . 1859
D. M. Roberts and
M. Guenthert and
R. Rodewald Isolation and characterization of the Fc
receptor from the fetal yolk sac of the
rat . . . . . . . . . . . . . . . . . . 1867
B. K. Sim and
P. A. Orlandi and
J. D. Haynes and
F. W. Klotz and
J. M. Carter and
D. Camus and
M. E. Zegans and
J. D. Chulay Primary structure of the 175K Plasmodium
falciparum erythrocyte binding antigen
and identification of a peptide which
elicits antibodies that inhibit malaria
merozoite invasion . . . . . . . . . . . 1877
D. J. Dix and
B. R. Eisenberg Myosin mRNA accumulation and
myofibrillogenesis at the myotendinous
junction of stretched muscle fibers . . 1885
I. C. Baines and
E. D. Korn Localization of myosin IC and myosin II
in \bionameAcanthamoeba castellanii by
indirect immunofluorescence and
immunogold electron microscopy . . . . . 1895
L. G. Cao and
Y. L. Wang Mechanism of the formation of
contractile ring in dividing cultured
animal cells. II. Cortical movement of
microinjected actin filaments . . . . . 1905
M. P. Rout and
J. V. Kilmartin Components of the yeast spindle and
spindle pole body . . . . . . . . . . . 1913
D. A. Skoufias and
T. L. Burgess and
L. Wilson Spatial and temporal colocalization of
the Golgi apparatus and microtubules
rich in detyrosinated tubulin . . . . . 1929
C. D. Thaler and
L. T. Haimo Regulation of organelle transport in
melanophores by calcineurin . . . . . . 1939
S. R. Heidemann and
P. Lamoureux and
R. E. Buxbaum Growth cone behavior and production of
traction force . . . . . . . . . . . . . 1949
W. T. Matten and
M. Aubry and
J. West and
P. F. Maness Tubulin is phosphorylated at tyrosine by
pp60c-src in nerve growth cone membranes 1959
J. M. Raats and
F. R. Pieper and
W. T. Vree Egberts and
K. N. Verrijp and
F. C. Ramaekers and
H. Bloemendal Assembly of amino-terminally deleted
desmin in vimentin-free cells . . . . . 1971
P. C. Wong and
D. W. Cleveland Characterization of dominant and
recessive assembly-defective mutations
in mouse neurofilament NF--M . . . . . . 1987
S. R. Gill and
P. C. Wong and
M. J. Monteiro and
D. W. Cleveland Assembly properties of dominant and
recessive mutations in the small mouse
neurofilament (NF--L) subunit . . . . . 2005
R. H. Selinfreund and
S. W. Barger and
M. J. Welsh and
L. J. Van Eldik Antisense inhibition of glial S100 beta
production results in alterations in
cell morphology, cytoskeletal
organization, and cell proliferation . . 2021
J. Stollberg and
S. E. Fraser Acetylcholine receptor clustering is
triggered by a change in the density of
a nonreceptor molecule . . . . . . . . . 2029
L. Thomas and
H. Betz Synaptophysin binds to physophilin, a
putative synaptic plasma membrane
protein . . . . . . . . . . . . . . . . 2041
D. J. Carey and
R. C. Stahl Identification of a lipid-anchored
heparan sulfate proteoglycan in Schwann
cells . . . . . . . . . . . . . . . . . 2053
L. Birkenberger and
W. Ip Properties of the desmin tail domain:
studies using synthetic peptides and
antipeptide antibodies . . . . . . . . . 2063
L. S. Musil and
B. A. Cunningham and
G. M. Edelman and
D. A. Goodenough Differential phosphorylation of the gap
junction protein connexin43 in
junctional communication-competent and
-deficient cell lines . . . . . . . . . 2077
S. J. Small and
R. Akeson Expression of the unique NCAM VASE exon
is independently regulated in distinct
tissues during development . . . . . . . 2089
K. M. Weidner and
J. Behrens and
J. Vandekerckhove and
W. Birchmeier Scatter factor: molecular
characteristics and effect on the
invasiveness of epithelial cells . . . . 2097
S. Regauer and
G. R. Seiler and
Y. Barrandon and
K. W. Easley and
C. C. Compton Epithelial origin of cutaneous anchoring
fibrils . . . . . . . . . . . . . . . . 2109
S. C. Stamatoglou and
R. C. Ge and
G. Mills and
T. D. Butters and
F. Zaidi and
R. C. Hughes Identification of a novel glycoprotein
(AGp110) involved in interactions of rat
liver parenchymal cells with fibronectin 2117
W. H. Burgess and
A. M. Shaheen and
M. Ravera and
M. Jaye and
P. J. Donohue and
J. A. Winkles Possible dissociation of the
heparin-binding and mitogenic activities
of heparin-binding (acidic fibroblast)
growth factor-1 from its
receptor-binding activities by
site-directed mutagenesis of a single
lysine residue . . . . . . . . . . . . . 2129
R. J. Shaw and
D. E. Doherty and
A. G. Ritter and
S. H. Benedict and
R. A. Clark Adherence-dependent increase in human
monocyte PDGF(B) mRNA is associated with
increases in c-fos, c-jun, and EGR2 mRNA 2139
M. W. Majesky and
M. A. Reidy and
D. F. Bowen-Pope and
C. E. Hart and
J. N. Wilcox and
S. M. Schwartz PDGF ligand and receptor gene expression
during repair of arterial injury . . . . 2149
V. M. Belkin and
A. M. Belkin and
V. E. Koteliansky Human smooth muscle VLA-1 integrin:
purification, substrate specificity,
localization in aorta, and expression
during development . . . . . . . . . . . 2159
C. Nathan and
E. Sanchez Tumor necrosis factor and CD11/CD18
(beta 2) integrins act synergistically
to lower cAMP in human neutrophils . . . 2171
G. J. Ciambrone and
P. J. McKeown-Longo Plasminogen activator inhibitor type I
stabilizes vitronectin-dependent
adhesions in HT-1080 cells . . . . . . . 2183
R. Doliana and
P. Bonaldo and
A. Colombatti Multiple forms of chicken alpha 3(VI)
collagen chain generated by alternative
splicing in type A repeated domains . . 2197
M. B. Roth and
C. Murphy and
J. G. Gall A monoclonal antibody that recognizes a
phosphorylated epitope stains lampbrush
chromosome loops and small granules in
the amphibian germinal vesicle . . . . . 2217
L. Powell and
B. Burke Internuclear exchange of an inner
nuclear membrane protein (p55) in
heterokaryons: in vivo evidence for the
interaction of p55 with the nuclear
lamina . . . . . . . . . . . . . . . . . 2225
U. T. Meier and
G. Blobel A nuclear localization signal binding
protein in the nucleolus . . . . . . . . 2235
J. W. Newport and
K. L. Wilson and
W. G. Dunphy A lamin-independent pathway for nuclear
envelope assembly . . . . . . . . . . . 2247
M. Moritz and
A. G. Paulovich and
Y. F. Tsay and
J. L. Woolford Depletion of yeast ribosomal proteins
L16 or rp59 disrupts ribosome assembly 2261
U. Klein and
M. Gernold and
P. M. Kloetzel Cell-specific accumulation of
\bionameDrosophila proteasomes (MCP)
during early development . . . . . . . . 2275
D. Görlich and
S. Prehn and
E. Hartmann and
J. Herz and
A. Otto and
R. Kraft and
M. Wiedmann and
S. Knespel and
B. Dobberstein and
T. A. Rapoport The signal sequence receptor has a
second subunit and is part of a
translocation complex in the endoplasmic
reticulum as probed by bifunctional
reagents . . . . . . . . . . . . . . . . 2283
J. G. Donaldson and
J. Lippincott-Schwartz and
G. S. Bloom and
T. E. Kreis and
R. D. Klausner Dissociation of a 110-kD peripheral
membrane protein from the Golgi
apparatus is an early event in brefeldin
A action . . . . . . . . . . . . . . . . 2295
S. L. Schmid and
L. L. Carter ATP is required for receptor-mediated
endocytosis in intact cells . . . . . . 2307
M. S. Robinson Cloning and expression of gamma-adaptin,
a component of clathrin-coated vesicles
associated with the Golgi apparatus . . 2319
J. K. Burkhardt and
S. Hester and
C. K. Lapham and
Y. Argon The lytic granules of natural killer
cells are dual-function organelles
combining secretory and pre-lysosomal
compartments . . . . . . . . . . . . . . 2327
P. E. Purdue and
Y. Takada and
C. J. Danpure Identification of mutations associated
with peroxisome-to-mitochondrion
mistargeting of alanine/glyoxylate
aminotransferase in primary
hyperoxaluria type 1 . . . . . . . . . . 2341
H. F. Steger and
T. Söllner and
M. Kiebler and
K. A. Dietmeier and
R. Pfaller and
K. S. Trülzsch and
M. Tropschug and
W. Neupert and
N. Pfanner Import of ADP/ATP carrier into
mitochondria: two receptors act in
parallel . . . . . . . . . . . . . . . . 2353
P. P. Breitfeld and
W. C. McKinnon and
K. E. Mostov Effect of nocodazole on vesicular
traffic to the apical and basolateral
surfaces of polarized MDCK cells . . . . 2365
D. Kraemer and
R. Koob and
B. Friedrichs and
D. Drenckhahn Two novel peripheral membrane proteins,
pasin 1 and pasin 2, associated with
Na+,K(+)-ATPase in various cells and
tissues . . . . . . . . . . . . . . . . 2375
J. Barsony and
J. W. Pike and
H. F. DeLuca and
S. J. Marx Immunocytology with microwave-fixed
fibroblasts shows 1
alpha,25-dihydroxyvitamin D3-dependent
rapid and estrogen-dependent slow
reorganization of vitamin D receptors 2385
C. L. Sundell and
R. H. Singer Actin mRNA localizes in the absence of
protein synthesis . . . . . . . . . . . 2397
D. L. Rimm and
D. A. Kaiser and
D. Bhandari and
P. Maupin and
D. P. Kiehart and
T. D. Pollard Identification of functional regions on
the tail of \bionameAcanthamoeba
myosin--II using recombinant fusion
proteins. I. High resolution epitope
mapping and characterization of
monoclonal antibody binding sites . . . 2405
J. H. Sinard and
D. L. Rimm and
T. D. Pollard Identification of functional regions on
the tail of \bionameAcanthamoeba
myosin--II using recombinant fusion
proteins. II. Assembly properties of
tails with NH2- and COOH-terminal
deletions . . . . . . . . . . . . . . . 2417
G. E. Lyons and
S. Schiaffino and
D. Sassoon and
P. Barton and
M. Buckingham Developmental regulation of myosin gene
expression in mouse cardiac muscle . . . 2427
J. E. Morgan and
E. P. Hoffman and
T. A. Partridge Normal myogenic cells from newborn mice
restore normal histology to degenerating
muscles of the mdx mouse . . . . . . . . 2437
J. V. Small and
M. Herzog and
M. Barth and
A. Draeger Supercontracted state of vertebrate
smooth muscle cell fragments reveals
myofilament lengths . . . . . . . . . . 2451
A. Draeger and
W. B. Amos and
M. Ikebe and
J. V. Small The cytoskeletal and contractile
apparatus of smooth muscle: contraction
bands and segmentation of the
contractile elements . . . . . . . . . . 2463
Z. Franck and
M. Footer and
A. Bretscher Microinjection of villin into cultured
cells induces rapid and long-lasting
changes in cell morphology but does not
inhibit cytokinesis, cell motility, or
membrane ruffling . . . . . . . . . . . 2475
Y. Yamakita and
S. Yamashiro and
F. Matsumura Microinjection of nonmuscle and smooth
muscle caldesmon into fibroblasts and
muscle cells . . . . . . . . . . . . . . 2487
B. F. Holifield and
A. Ishihara and
K. Jacobson Comparative behavior of membrane
protein-antibody complexes on motile
fibroblasts: implications for a
mechanism of capping . . . . . . . . . . 2499
S. Felder and
E. L. Elson Mechanics of fibroblast locomotion:
quantitative analysis of forces and
motions at the leading lamellas of
fibroblasts . . . . . . . . . . . . . . 2513
D. Kerboeuf and
J. Cohen A Ca$^{2+}$ influx associated with
exocytosis is specifically abolished in
a Paramecium exocytotic mutant . . . . . 2527
R. Hinrichsen and
E. Wilson and
T. Lukas and
T. Craig and
J. Schultz and
D. M. Watterson Analysis of the molecular basis of
calmodulin defects that affect ion
channel-mediated cellular responses:
site-specific mutagenesis and
microinjection . . . . . . . . . . . . . 2537
A. Miyauchi and
K. A. Hruska and
E. M. Greenfield and
R. Duncan and
J. Alvarez and
R. Barattolo and
S. Colucci and
A. Zambonin-Zallone and
S. L. Teitelbaum and
A. Teti Osteoclast cytosolic calcium, regulated
by voltage-gated calcium channels and
extracellular calcium, controls podosome
assembly and bone resorption . . . . . . 2543
C. C. Schroeder and
A. K. Fok and
R. D. Allen Vesicle transport along microtubular
ribbons and isolation of cytoplasmic
dynein from Paramecium . . . . . . . . . 2553
I. Irminger-Finger and
R. A. Laymon and
L. S. Goldstein Analysis of the primary sequence and
microtubule-binding region of the
\bionameDrosophila 205K MAP . . . . . . 2563
V. Berlin and
C. A. Styles and
G. R. Fink BIK1, a protein required for microtubule
function during mating and mitosis in
\bionameSaccharomyces cerevisiae,
colocalizes with tubulin . . . . . . . . 2573
P. J. MacKinnon and
B. C. Powell and
G. E. Rogers Structure and expression of genes for a
class of cysteine-rich proteins of the
cuticle layers of differentiating wool
and hair follicles . . . . . . . . . . . 2587
P. Blount and
M. M. Smith and
J. P. Merlie Assembly intermediates of the mouse
muscle nicotinic acetylcholine receptor
in stably transfected fibroblasts . . . 2601
P. Blount and
J. P. Merlie Mutational analysis of muscle nicotinic
acetylcholine receptor subunit assembly 2613
C. Toyoshima and
N. Unwin Three-dimensional structure of the
acetylcholine receptor by cryoelectron
microscopy and helical image
reconstruction . . . . . . . . . . . . . 2623
F. Keller and
S. Schacher Neuron-specific membrane glycoproteins
promoting neurite fasciculation in
\bionameAplysia californica . . . . . . 2637
L. Pedraza and
G. C. Owens and
L. A. Green and
J. L. Salzer The myelin-associated glycoproteins:
membrane disposition, evidence of a
novel disulfide linkage between
immunoglobulin-like domains, and
posttranslational palmitylation . . . . 2651
D. Muir and
S. Varon and
M. Manthorpe Schwann cell proliferation in vitro is
under negative autocrine control . . . . 2663
D. D. Mikol and
M. J. Alexakos and
C. A. Bayley and
R. S. Lemons and
M. M. Le Beau and
K. Stefansson Structure and chromosomal localization
of the gene for the
oligodendrocyte-myelin glycoprotein . . 2673
R. J. Wieser and
S. Schütz and
G. Tschank and
H. Thomas and
H. P. Dienes and
F. Oesch Isolation and characterization of a
60-70-kD plasma membrane glycoprotein
involved in the contact-dependent
inhibition of growth . . . . . . . . . . 2681
J. N. Feder and
C. J. Guidos and
B. Kusler and
C. Carswell and
D. Lewis and
R. T. Schimke A cell cycle analysis of growth-related
genes expressed during T lymphocyte
maturation . . . . . . . . . . . . . . . 2693
B. M. Veneziani and
G. Villone and
R. Romano and
A. Di Carlo and
C. Garbi and
D. Tramontano The tissue-specific pathways regulating
cell proliferation are inherited
independently in somatic hybrid between
thyroid and liver cells . . . . . . . . 2703
K. S. O'Shea and
L. H. Liu and
L. H. Kinnunen and
V. M. Dixit Role of the extracellular matrix protein
thrombospondin in the early development
of the mouse embryo . . . . . . . . . . 2713
J. L. Bixby and
P. Jhabvala Extracellular matrix molecules and cell
adhesion molecules induce neurites
through different mechanisms . . . . . . 2725
P. K. Haugen and
J. B. McCarthy and
A. P. Skubitz and
L. T. Furcht and
P. C. Letourneau Recognition of the A chain
carboxy-terminal heparin binding region
of fibronectin involves multiple sites:
two contiguous sequences act
independently to promote neural cell
adhesion . . . . . . . . . . . . . . . . 2733
S. I. Simon and
J. D. Chambers and
L. A. Sklar Flow cytometric analysis and modeling of
cell--cell adhesive interactions: the
neutrophil as a model . . . . . . . . . 2747
D. D. True and
M. S. Singer and
L. A. Lasky and
S. D. Rosen Requirement for sialic acid on the
endothelial ligand of a lymphocyte
homing receptor . . . . . . . . . . . . 2757
M. Culty and
K. Miyake and
P. W. Kincade and
E. Sikorski and
E. C. Butcher and
C. Underhill and
E. Silorski The hyaluronate receptor is a member of
the CD44 (H--CAM) family of cell surface
glycoproteins . . . . . . . . . . . . . 2765
F. Gonzalez-Fernandez and
J. I. Healy Early expression of the gene for
interphotoreceptor retinol-binding
protein during photoreceptor
differentiation suggests a critical role
for the interphotoreceptor matrix in
retinal development . . . . . . . . . . 2775
E. Brown and
L. Hooper and
T. Ho and
H. Gresham Integrin-associated protein: a 50-kD
plasma membrane antigen physically and
functionally associated with integrins 2785
I. F. Charo and
L. Nannizzi and
J. W. Smith and
D. A. Cheresh The vitronectin receptor alpha v beta 3
binds fibronectin and acts in concert
with alpha 5 beta 1 in promoting
cellular attachment and spreading on
fibronectin . . . . . . . . . . . . . . 2795
Y. Hiraoka and
D. A. Agard and
J. W. Sedat Temporal and spatial coordination of
chromosome movement, spindle formation,
and nuclear envelope breakdown during
prometaphase in \bionameDrosophila
melanogaster embryos . . . . . . . . . . 2815
E. C. Hurt Targeting of a cytosolic protein to the
nuclear periphery . . . . . . . . . . . 2829
E. R. Wood and
W. C. Earnshaw Mitotic chromatin condensation in vitro
using somatic cell extracts and nuclei
with variable levels of endogenous
topoisomerase II . . . . . . . . . . . . 2839
P. A. Bresnahan and
R. Leduc and
L. Thomas and
J. Thorner and
H. L. Gibson and
A. J. Brake and
P. J. Barr and
G. Thomas Human fur gene encodes a yeast KEX2-like
endoprotease that cleaves pro--beta--NGF
in vivo . . . . . . . . . . . . . . . . 2851
C. M. Sanderson and
J. S. Crowe and
D. I. Meyer Protein retention in yeast rough
endoplasmic reticulum: expression and
assembly of human ribophorin I . . . . . 2861
T. A. Vida and
T. R. Graham and
S. D. Emr In vitro reconstitution of
intercompartmental protein transport to
the yeast vacuole . . . . . . . . . . . 2871
M. Aridor and
R. Sagi-Eisenberg Neomycin is a potent secretagogue of
mast cells that directly activates a
GTP-binding protein involved in
exocytosis . . . . . . . . . . . . . . . 2885
D. Gravotta and
M. Adesnik and
D. D. Sabatini Transport of influenza HA from the
trans-Golgi network to the apical
surface of MDCK cells permeabilized in
their basolateral plasma membranes:
energy dependence and involvement of
GTP-binding proteins . . . . . . . . . . 2893
A. W. Brändli and
R. G. Parton and
K. Simons Transcytosis in MDCK cells:
identification of glycoproteins
transported bidirectionally between both
plasma membrane domains . . . . . . . . 2909
H. P. Wessels and
G. H. Hansen and
C. Fuhrer and
A. T. Look and
H. Sjöström and
O. Norén and
M. Spiess Aminopeptidase N is directly sorted to
the apical domain in MDCK cells . . . . 2923
K. G. Rothberg and
Y. S. Ying and
B. A. Kamen and
R. G. Anderson Cholesterol controls the clustering of
the glycophospholipid-anchored membrane
receptor for $5$-methyltetrahydrofolate 2931
W. F. Lathrop and
E. P. Carmichael and
D. G. Myles and
P. Primakoff cDNA cloning reveals the molecular
structure of a sperm surface protein,
PH-20, involved in sperm-egg adhesion
and the wide distribution of its gene
among mammals . . . . . . . . . . . . . 2939
K. R. Foltz and
W. J. Lennarz Purification and characterization of an
extracellular fragment of the sea urchin
egg receptor for sperm . . . . . . . . . 2951
E. P. Morris and
G. Nneji and
J. M. Squire The three-dimensional structure of the
nemaline rod Z-band . . . . . . . . . . 2961
L. G. Tilney and
P. S. Connelly and
D. A. Portnoy Actin filament nucleation by the
bacterial pathogen, \bionameListeria
monocytogenes . . . . . . . . . . . . . 2979
D. R. Swartz and
M. L. Greaser and
B. B. Marsh Regulation of binding of subfragment 1
in isolated rigor myofibrils . . . . . . 2989
R. Pepperkok and
M. H. Bré and
J. Davoust and
T. E. Kreis Microtubules are stabilized in confluent
epithelial cells but not in fibroblasts 3003
M. H. Bré and
R. Pepperkok and
A. M. Hill and
N. Levilliers and
W. Ansorge and
E. H. Stelzer and
E. Karsenti Regulation of microtubule dynamics and
nucleation during polarization in MDCK
II cells . . . . . . . . . . . . . . . . 3013
R. Scaife and
R. L. Margolis Biochemical and immunochemical analysis
of rat brain dynamin interaction with
microtubules and organelles in vivo and
in vitro . . . . . . . . . . . . . . . . 3023
F. Widmer and
P. Caroni Identification, localization, and
primary structure of CAP-23, a
particle-bound cytosolic protein of
early development . . . . . . . . . . . 3035
P. A. Coulombe and
Y. M. Chan and
K. Albers and
E. Fuchs Deletions in epidermal keratins leading
to alterations in filament organization
in vivo and in intermediate filament
assembly in vitro . . . . . . . . . . . 3049
T. F. Lane and
E. H. Sage Functional mapping of SPARC: peptides
from two distinct Ca+(+)-binding sites
modulate cell shape . . . . . . . . . . 3065
P. J. Mansfield and
L. A. Boxer and
S. J. Suchard Thrombospondin stimulates motility of
human neutrophils . . . . . . . . . . . 3077
E. J. de la Rosa and
J. F. Kayyem and
J. M. Roman and
Y. D. Stierhof and
W. J. Dreyer and
U. Schwarz Topologically restricted appearance in
the developing chick retinotectal system
of Bravo, a neural surface protein:
experimental modulation by environmental
cues . . . . . . . . . . . . . . . . . . 3087
T. David-Pfeuty and
Y. Nouvian-Dooghe Immunolocalization of the cellular src
protein in interphase and mitotic NIH
c-src overexpresser cells . . . . . . . 3097
A. Golden and
J. S. Brugge and
S. J. Shattil Role of platelet membrane glycoprotein
IIb--IIIa in agonist-induced tyrosine
phosphorylation of platelet proteins . . 3117
M. S. Diamond and
D. E. Staunton and
A. R. de Fougerolles and
S. A. Stacker and
J. Garcia-Aguilar and
M. L. Hibbs and
T. A. Springer ICAM-1 (CD54): a counter-receptor for
Mac-1 (CD11b/CD18) . . . . . . . . . . . 3129
W. G. Carter and
P. Kaur and
S. G. Gil and
P. J. Gahr and
E. A. Wayner Distinct functions for integrins alpha 3
beta 1 in focal adhesions and alpha 6
beta 4/bullous pemphigoid antigen in a
new stable anchoring contact (SAC) of
keratinocytes: relation to
hemidesmosomes . . . . . . . . . . . . . 3141
W. S. Argraves and
H. Tran and
W. H. Burgess and
K. Dickerson Fibulin is an extracellular matrix and
plasma glycoprotein with repeated domain
structure . . . . . . . . . . . . . . . 3155
G. David and
V. Lories and
B. Decock and
P. Marynen and
J. J. Cassiman and
H. Van den Berghe Molecular cloning of a
phosphatidylinositol-anchored membrane
heparan sulfate proteoglycan from human
lung fibroblasts . . . . . . . . . . . . 3165
W. B. Stallcup and
K. Dahlin and
P. Healy Interaction of the NG2 chondroitin
sulfate proteoglycan with type VI
collagen . . . . . . . . . . . . . . . . 3177
E. Fuchs Epidermal differentiation: the bare
essentials . . . . . . . . . . . . . . . 2807
M. T. Murray and
G. Krohne and
W. W. Franke Different forms of soluble cytoplasmic
mRNA binding proteins and particles in
\bionameXenopus laevis oocytes and
embryos . . . . . . . . . . . . . . . . 1
G. Mugrauer and
P. Ekblom Contrasting expression patterns of three
members of the myc family of
protooncogenes in the developing and
adult mouse kidney . . . . . . . . . . . 13
A. Franzusoff and
K. Redding and
J. Crosby and
R. S. Fuller and
R. Schekman Localization of components involved in
protein transport and processing through
the yeast Golgi apparatus . . . . . . . 27
S. G. Miller and
H. P. Moore Reconstitution of constitutive secretion
using semi-intact cells: regulation by
GTP but not calcium . . . . . . . . . . 39
A. Sorkin and
S. Krolenko and
N. Kudrjavtceva and
J. Lazebnik and
L. Teslenko and
A. M. Soderquist and
N. Nikolsky Recycling of epidermal growth
factor-receptor complexes in A431 cells:
identification of dual pathways . . . . 55
S. K. Lemmon and
A. Pellicena-Palle and
K. Conley and
C. L. Freund Sequence of the clathrin heavy chain
from \bionameSaccharomyces cerevisiae
and requirement of the COOH terminus for
clathrin function . . . . . . . . . . . 65
R. Einstein and
C. A. Gabel Cell- and ligand-specific
dephosphorylation of acid hydrolases:
evidence that the mannose
$6$-phosphatase is controlled by
compartmentalization . . . . . . . . . . 81
T. Schnyder and
H. Gross and
H. Winkler and
H. M. Eppenberger and
T. Wallimann Structure of the mitochondrial creatine
kinase octamer: high-resolution
shadowing and image averaging of single
molecules and formation of linear
filaments under specific staining
conditions . . . . . . . . . . . . . . . 95
J. L. Milne and
M. B. Coukell A Ca$^{2+}$ transport system associated
with the plasma membrane of
\bionameDictyostelium discoideum is
activated by different chemoattractant
receptors . . . . . . . . . . . . . . . 103
M. de Brabander and
R. Nuydens and
A. Ishihara and
B. Holifield and
K. Jacobson and
H. Geerts Lateral diffusion and retrograde
movements of individual cell surface
components on single motile cells
observed with Nanovid microscopy . . . . 111
A. Ruknudin and
M. J. Song and
F. Sachs The ultrastructure of patch-clamped
membranes: a study using high voltage
electron microscopy . . . . . . . . . . 125
K. Ohlendieck and
J. M. Ervasti and
J. B. Snook and
K. P. Campbell Dystrophin-glycoprotein complex is
highly enriched in isolated skeletal
muscle sarcolemma . . . . . . . . . . . 135
P. W. Marks and
B. Hendey and
F. R. Maxfield Attachment to fibronectin or vitronectin
makes human neutrophil migration
sensitive to alterations in cytosolic
free calcium concentration . . . . . . . 149
K. S. Riddelle and
K. J. Green and
J. C. Jones Formation of hemidesmosomes in vitro by
a transformed rat bladder cell line . . 159
M. J. Elices and
L. A. Urry and
M. E. Hemler Receptor functions for the integrin
VLA-3: fibronectin, collagen, and
laminin binding are differentially
influenced by Arg--Gly--Asp peptide and
by divalent cations . . . . . . . . . . 169
C. Polizzi and
L. Clarke The chromatin structure of centromeres
from fission yeast: differentiation of
the central core that correlates with
function . . . . . . . . . . . . . . . . 191
A. M. Whalen and
M. McConnell and
P. A. Fisher Developmental regulation of
\bionameDrosophila DNA topoisomerase II 203
N. Michaud and
D. S. Goldfarb Multiple pathways in nuclear transport:
the import of U2 snRNP occurs by a novel
kinetic pathway . . . . . . . . . . . . 215
N. L. Kedersha and
J. E. Heuser and
D. C. Chugani and
L. H. Rome Vaults. III. Vault ribonucleoprotein
particles open into flower-like
structures with octagonal symmetry . . . 225
N. J. Coppard and
K. Poulsen and
H. O. Madsen and
J. Frydenberg and
B. F. Clark 42Sp48 in previtellogenic
\bionameXenopus oocytes is structurally
homologous to EF-1 alpha and may be a
stage-specific elongation factor . . . . 237
J. E. Park and
J. M. Lopez and
E. B. Cluett and
W. J. Brown Identification of a membrane
glycoprotein found primarily in the
prelysosomal endosome compartment . . . 245
R. Persson and
R. F. Pettersson Formation and intracellular transport of
a heterodimeric viral spike protein
complex . . . . . . . . . . . . . . . . 257
P. Grellier and
D. Rigomier and
V. Clavey and
J. C. Fruchart and
J. Schrevel Lipid traffic between high density
lipoproteins and Plasmodium
falciparum-infected red blood cells . . 267
L. M. Zheng and
A. Zychlinsky and
C. C. Liu and
D. M. Ojcius and
J. D. Young Extracellular ATP as a trigger for
apoptosis or programmed cell death . . . 279
S. H. Yuan and
W. Arnold and
A. O. Jorgensen Biogenesis of transverse tubules and
triads: immunolocalization of the
1,4-dihydropyridine receptor, TS28, and
the ryanodine receptor in rabbit
skeletal muscle developing in situ . . . 289
F. D. Miller and
T. C. Mathew and
J. G. Toma Regulation of nerve growth factor
receptor gene expression by nerve growth
factor in the developing peripheral
nervous system . . . . . . . . . . . . . 303
H. Taniura and
C. H. Kuo and
Y. Hayashi and
N. Miki Purification and characterization of an
82-kD membrane protein as a neurite
outgrowth factor binding protein:
possible involvement of NOF binding
protein in axonal outgrowth in
developing retina . . . . . . . . . . . 313
D. Giulian and
B. Johnson and
J. F. Krebs and
J. K. George and
M. Tapscott Microglial mitogens are produced in the
developing and injured mammalian brain 323
R. Bar-Shavit and
V. Sabbah and
M. G. Lampugnani and
P. C. Marchisio and
J. W. Fenton and
I. Vlodavsky and
E. Dejana An Arg--Gly--Asp sequence within
thrombin promotes endothelial cell
adhesion . . . . . . . . . . . . . . . . 335
Y. van Kooyk and
P. Weder and
F. Hogervorst and
A. J. Verhoeven and
G. van Seventer and
A. A. te Velde and
J. Borst and
G. D. Keizer and
C. G. Figdor Activation of LFA-1 through a
Ca2(+)-dependent epitope stimulates
lymphocyte adhesion . . . . . . . . . . 345
A. Weller and
S. Beck and
P. Ekblom Amino acid sequence of mouse tenascin
and differential expression of two
tenascin isoforms during embryogenesis 355
P. Arvan and
J. Lee Regulated and constitutive protein
targeting can be distinguished by
secretory polarity in thyroid epithelial
cells . . . . . . . . . . . . . . . . . 365
B. Su and
G. L. Waneck and
R. A. Flavell and
A. L. Bothwell The glycosyl phosphatidylinositol anchor
is critical for Ly-6A/E-mediated T cell
activation . . . . . . . . . . . . . . . 377
R. M. Lynch and
K. E. Fogarty and
F. S. Fay Modulation of hexokinase association
with mitochondria analyzed with
quantitative three-dimensional confocal
microscopy . . . . . . . . . . . . . . . 385
R. Foisner and
B. Feldman and
L. Sander and
G. Wiche Monoclonal antibody mapping of
structural and functional plectin
epitopes . . . . . . . . . . . . . . . . 397
J. H. Hartwig and
M. DeSisto The cytoskeleton of the resting human
blood platelet: structure of the
membrane skeleton and its attachment to
actin filaments . . . . . . . . . . . . 407
A. Tousson and
C. Zeng and
B. R. Brinkley and
M. M. Valdivia Centrophilin: a novel mitotic spindle
protein involved in microtubule
nucleation . . . . . . . . . . . . . . . 427
R. Kamiya and
E. Kurimoto and
E. Muto Two types of \bionameChlamydomonas
flagellar mutants missing different
components of inner-arm dynein . . . . . 441
E. T. Stoeckli and
T. B. Kuhn and
C. O. Duc and
M. A. Ruegg and
P. Sonderegger The axonally secreted protein axonin-1
is a potent substratum for neurite
growth . . . . . . . . . . . . . . . . . 449
L. Morgan and
K. R. Jessen and
R. Mirsky The effects of cAMP on differentiation
of cultured Schwann cells: progression
from an early phenotype (04+) to a
myelin phenotype (P0+, GFAP-, N-CAM-,
NGF-receptor-) depends on growth
inhibition . . . . . . . . . . . . . . . 457
A. Sorkin and
B. Westermark and
C. H. Heldin and
L. Claesson-Welsh Effect of receptor kinase inactivation
on the rate of internalization and
degradation of PDGF and the PDGF
beta-receptor . . . . . . . . . . . . . 469
M. G. Lampugnani and
M. Resnati and
E. Dejana and
P. C. Marchisio The role of integrins in the maintenance
of endothelial monolayer integrity . . . 479
K. L. Moore and
A. Varki and
R. P. McEver GMP-140 binds to a glycoprotein receptor
on human neutrophils: evidence for a
lectin-like interaction . . . . . . . . 491
L. C. Gerstenfeld and
W. J. Landis Gene expression and extracellular matrix
ultrastructure of a mineralizing
chondrocyte cell culture system . . . . 501
G. Dessev and
C. Iovcheva-Dessev and
J. R. Bischoff and
D. Beach and
R. Goldman A complex containing p34cdc2 and cyclin
B phosphorylates the nuclear lamin and
disassembles nuclei of clam oocytes in
vitro . . . . . . . . . . . . . . . . . 523
H. B. Kim and
B. K. Haarer and
J. R. Pringle Cellular morphogenesis in the
\bionameSaccharomyces cerevisiae cell
cycle: localization of the CDC3 gene
product and the timing of events at the
budding site . . . . . . . . . . . . . . 535
G. P. Vigers and
M. J. Lohka A distinct vesicle population targets
membranes and pore complexes to the
nuclear envelope in \bionameXenopus eggs 545
G. H. Leno and
R. A. Laskey The nuclear membrane determines the
timing of DNA replication in
\bionameXenopus egg extracts . . . . . . 557
J. Lippincott-Schwartz and
J. Glickman and
J. G. Donaldson and
J. Robbins and
T. E. Kreis and
K. B. Seamon and
M. P. Sheetz and
R. D. Klausner Forskolin inhibits and reverses the
effects of brefeldin A on Golgi
morphology by a cAMP-independent
mechanism . . . . . . . . . . . . . . . 567
J. G. Donaldson and
J. Lippincott-Schwartz and
R. D. Klausner Guanine nucleotides modulate the effects
of brefeldin A in semipermeable cells:
regulation of the association of a
110-kD peripheral membrane protein with
the Golgi apparatus . . . . . . . . . . 579
P. J. Moore and
K. M. Swords and
M. A. Lynch and
L. A. Staehelin Spatial organization of the assembly
pathways of glycoproteins and complex
polysaccharides in the Golgi apparatus
of plants . . . . . . . . . . . . . . . 589
L. A. Payan and
K. Cline A stromal protein factor maintains the
solubility and insertion competence of
an imported thylakoid membrane protein 603
T. Phalen and
M. Kielian Cholesterol is required for infection by
Semliki Forest virus . . . . . . . . . . 615
P. G. Gillespie and
A. J. Hudspeth High-purity isolation of bullfrog hair
bundles and subcellular and topological
localization of constituent proteins . . 625
D. Drenckhahn and
K. Engel and
D. Höfer and
C. Merte and
L. Tilney and
M. Tilney Three different actin filament
assemblies occur in every hair cell:
each contains a specific actin
crosslinking protein . . . . . . . . . . 641
T. C. Hoock and
P. M. Newcomb and
I. M. Herman Beta actin and its mRNA are localized at
the plasma membrane and the regions of
moving cytoplasm during the cellular
response to injury . . . . . . . . . . . 653
L. Eichinger and
A. A. Noegel and
M. Schleicher Domain structure in actin-binding
proteins: expression and functional
characterization of truncated severin 665
T. T. Egelhoff and
S. S. Brown and
J. A. Spudich Spatial and temporal control of
nonmuscle myosin localization:
identification of a domain that is
necessary for myosin filament
disassembly in vivo . . . . . . . . . . 677
P. Feick and
R. Foisner and
G. Wiche Immunolocalization and molecular
properties of a high molecular weight
microtubule-bundling protein (syncolin)
from chicken erythrocytes . . . . . . . 689
G. Piperno and
Z. Ramanis The proximal portion of
\bionameChlamydomonas flagella contains
a distinct set of inner dynein arms . . 701
N. Grandin and
M. Charbonneau Intracellular free calcium oscillates
during cell division of \bionameXenopus
embryos . . . . . . . . . . . . . . . . 711
K. Fushimi and
A. S. Verkman Low viscosity in the aqueous domain of
cell cytoplasm measured by picosecond
polarization microfluorimetry . . . . . 719
F. M. Butterworth and
M. Bownes and
V. S. Burde Genetically modified yolk proteins
precipitate in the adult
\bionameDrosophila fat body . . . . . . 727
L. G. Tilney and
T. J. Cooke and
P. S. Connelly and
M. S. Tilney The structure of plasmodesmata as
revealed by plasmolysis, detergent
extraction, and protease digestion . . . 739
K. D. Patel and
G. A. Zimmerman and
S. M. Prescott and
R. P. McEver and
T. M. McIntyre Oxygen radicals induce human endothelial
cells to express GMP-140 and bind
neutrophils . . . . . . . . . . . . . . 749
P. C. Marchisio and
S. Bondanza and
O. Cremona and
R. Cancedda and
M. De Luca Polarized expression of integrin
receptors (alpha 6 beta 4, alpha 2 beta
1, alpha 3 beta 1, and alpha v beta 5)
and their relationship with the
cytoskeleton and basement membrane
matrix in cultured human keratinocytes 761
H. M. Blau and
D. Baltimore Differentiation requires continuous
regulation . . . . . . . . . . . . . . . 781
C. A. Ascoli and
G. G. Maul Identification of a novel nuclear domain 785
T. Enoch and
M. Peter and
P. Nurse and
E. A. Nigg p34cdc2 acts as a lamin kinase in
fission yeast . . . . . . . . . . . . . 797
R. N. Thrift and
D. W. Andrews and
P. Walter and
A. E. Johnson A nascent membrane protein is located
adjacent to ER membrane proteins
throughout its integration and
translation . . . . . . . . . . . . . . 809
Y. Goda and
S. R. Pfeffer Identification of a novel,
N-ethylmaleimide-sensitive cytosolic
factor required for vesicular transport
from endosomes to the trans-Golgi
network in vitro . . . . . . . . . . . . 823
B. R. Miller and
M. G. Cumsky An unusual mitochondrial import pathway
for the precursor to yeast cytochrome c
oxidase subunit Va . . . . . . . . . . . 833
L. Matsuuchi and
R. B. Kelly Constitutive and basal secretion from
the endocrine cell line, AtT-20 . . . . 843
T. E. McGraw and
B. Pytowski and
J. Arzt and
C. Ferrone Mutagenesis of the human transferrin
receptor: two cytoplasmic phenylalanines
are required for efficient
internalization and a second-site
mutation is capable of reverting an
internalization-defective phenotype . . 853
D. Gundersen and
J. Orlowski and
E. Rodriguez-Boulan Apical polarity of Na,K--ATPase in
retinal pigment epithelium is linked to
a reversal of the ankyrin-fodrin
submembrane cytoskeleton . . . . . . . . 863
C. A. Schoenenberger and
A. Zuk and
D. Kendall and
K. S. Matlin Multilayering and loss of apical
polarity in MDCK cells transformed with
viral K-ras . . . . . . . . . . . . . . 873
M. P. Tranter and
S. P. Sugrue and
M. A. Schwartz Binding of actin to liver cell
membranes: the state of membrane-bound
actin . . . . . . . . . . . . . . . . . 891
F. Stark and
R. Golla and
V. T. Nachmias Formation and contraction of a
microfilamentous shell in
saponin-permeabilized platelets . . . . 903
S. Kawamoto and
R. S. Adelstein Chicken nonmuscle myosin heavy chains:
differential expression of two mRNAs and
evidence for two different polypeptides 915
K. E. Sawin and
T. J. Mitchison Mitotic spindle assembly by two
different pathways in vitro . . . . . . 925
K. E. Sawin and
T. J. Mitchison Poleward microtubule flux mitotic
spindles assembled in vitro . . . . . . 941
P. A. Maher Tissue-dependent regulation of protein
tyrosine kinase activity during
embryonic development . . . . . . . . . 955
J. F. Boylan and
L. J. Gudas Overexpression of the cellular retinoic
acid binding protein--I (CRABP--I)
results in a reduction in
differentiation-specific gene expression
in F9 teratocarcinoma cells . . . . . . 965
A. S. Polans and
J. Buczy\lko and
J. Crabb and
K. Palczewski A photoreceptor calcium binding protein
is recognized by autoantibodies obtained
from patients with cancer-associated
retinopathy . . . . . . . . . . . . . . 981
K. F. Meiri and
L. E. Bickerstaff and
J. E. Schwob Monoclonal antibodies show that kinase C
phosphorylation of GAP-43 during
axonogenesis is both spatially and
temporally restricted in vivo . . . . . 991
M. S. Saedi and
W. G. Conroy and
J. Lindstrom Assembly of Torpedo acetylcholine
receptors in \bionameXenopus oocytes . . 1007
M. P. Burgoon and
M. Grumet and
V. Mauro and
G. M. Edelman and
B. A. Cunningham Structure of the chicken neuron-glia
cell adhesion molecule, Ng--CAM: origin
of the polypeptides and relation to the
Ig superfamily . . . . . . . . . . . . . 1017
C. A. Prater and
J. Plotkin and
D. Jaye and
W. A. Frazier The properdin-like type I repeats of
human thrombospondin contain a cell
attachment site . . . . . . . . . . . . 1031
E. A. Turley and
L. Austen and
K. Vandeligt and
C. Clary Hyaluronan and a cell-associated
hyaluronan binding protein regulate the
locomotion of ras-transformed cells . . 1041
E. J. de la Rosa Topologically restricted appearance in
the developing chick retinotectal system
of Bravo, a neural surface protein:
experimental modulation by environmental
cues . . . . . . . . . . . . . . . . . . 1049
Y. G. Xing and
J. B. Lawrence Preservation of specific RNA
distribution within the
chromatin-depleted nuclear substructure
demonstrated by in situ hybridization
coupled with biochemical fractionation 1055
B. Kastner and
M. Bach and
R. Lührmann Electron microscopy of U4/U6 snRNP
reveals a Y-shaped U4 and U6 RNA
containing domain protruding from the U4
core RNP . . . . . . . . . . . . . . . . 1065
M. C. Dabauvalle and
K. Loos and
H. Merkert and
U. Scheer Spontaneous assembly of pore
complex-containing membranes (''annulate
lamellae'') in \bionameXenopus egg
extract in the absence of chromatin . . 1073
D. A. Compton and
T. J. Yen and
D. W. Cleveland Identification of novel
centromere/kinetochore-associated
proteins using monoclonal antibodies
generated against human mitotic
chromosome scaffolds . . . . . . . . . . 1083
E. Degen and
D. B. Williams Participation of a novel 88-kD protein
in the biogenesis of murine class I
histocompatibility molecules . . . . . . 1099
R. Bowser and
P. Novick Sec15 protein, an essential component of
the exocytotic apparatus, is associated
with the plasma membrane and with a
soluble 19.5S particle . . . . . . . . . 1117
P. G. Woodman and
G. Warren Isolation of functional, coated,
endocytic vesicles . . . . . . . . . . . 1133
M. Edidin and
I. Stroynowski Differences between the lateral
organization of conventional and
inositol phospholipid-anchored membrane
proteins. A further definition of
micrometer scale membrane domains . . . 1143
C. Y. Dadabay and
E. Patton and
J. A. Cooper and
L. J. Pike Lack of correlation between changes in
polyphosphoinositide levels and
actin/gelsolin complexes in A431 cells
treated with epidermal growth factor . . 1151
J. R. Apgar Regulation of the antigen-induced
F-actin response in rat basophilic
leukemia cells by protein kinase C . . . 1157
M. Coue and
V. A. Lombillo and
J. R. McIntosh Microtubule depolymerization promotes
particle and chromosome movement in
vitro . . . . . . . . . . . . . . . . . 1165
F. Verde and
J. M. Berrez and
C. Antony and
E. Karsenti Taxol-induced microtubule asters in
mitotic extracts of \bionameXenopus
eggs: requirement for phosphorylated
factors and cytoplasmic dynein . . . . . 1177
T. Shimizu and
K. Furusawa and
S. Ohashi and
Y. Y. Toyoshima and
M. Okuno and
F. Malik and
R. D. Vale Nucleotide specificity of the enzymatic
and motile activities of dynein,
kinesin, and heavy meromyosin . . . . . 1189
M. Schliwa and
T. Shimizu and
R. D. Vale and
U. Euteneuer Nucleotide specificities of anterograde
and retrograde organelle transport in
Reticulomyxa are indistinguishable . . . 1199
D. E. Weinstein and
M. L. Shelanski and
R. K. Liem Suppression by antisense mRNA
demonstrates a requirement for the glial
fibrillary acidic protein in the
formation of stable astrocytic processes
in response to neurons . . . . . . . . . 1205
R. O. Lockerbie and
V. E. Miller and
K. H. Pfenninger Regulated plasmalemmal expansion in
nerve growth cones . . . . . . . . . . . 1215
M. M. Daston and
N. Ratner Expression of P30, a protein with
adhesive properties, in Schwann cells
and neurons of the developing and
regenerating peripheral nerve . . . . . 1229
N. Usuda and
Y. Kong and
M. Hagiwara and
C. Uchida and
M. Terasawa and
T. Nagata and
H. Hidaka Differential localization of protein
kinase C isozymes in retinal neurons . . 1241
M. E. Jaconi and
J. M. Theler and
W. Schlegel and
R. D. Appel and
S. D. Wright and
P. D. Lew Multiple elevations of cytosolic-free
Ca$^{2+}$ in human neutrophils:
initiation by adherence receptors of the
integrin family . . . . . . . . . . . . 1249
W. C. Lee and
Z. X. Xue and
T. Mél\`ese The NSR1 gene encodes a protein that
specifically binds nuclear localization
sequences and has two RNA recognition
motifs . . . . . . . . . . . . . . . . . 1
G. T. Kitten and
E. A. Nigg The CaaX motif is required for
isoprenylation, carboxyl methylation,
and nuclear membrane association of
lamin B2 . . . . . . . . . . . . . . . . 13
S. High and
N. Flint and
B. Dobberstein Requirements for the membrane insertion
of signal-anchor type proteins . . . . . 25
S. High and
D. Görlich and
M. Wiedmann and
T. A. Rapoport and
B. Dobberstein The identification of proteins in the
proximity of signal-anchor sequences
during their targeting to and insertion
into the membrane of the ER . . . . . . 35
A. Schweizer and
K. Matter and
C. M. Ketcham and
H. P. Hauri The isolated ER--Golgi intermediate
compartment exhibits properties that are
different from ER and cis-Golgi . . . . 45
J. Shim and
A. P. Newman and
S. Ferro-Novick The BOS1 gene encodes an essential 27-kD
putative membrane protein that is
required for vesicular transport from
the ER to the Golgi complex in yeast . . 55
G. Isaya and
F. Kalousek and
W. A. Fenton and
L. E. Rosenberg Cleavage of precursors by the
mitochondrial processing peptidase
requires a compatible mature protein or
an intermediate octapeptide . . . . . . 65
I. W. Caras An internally positioned signal can
direct attachment of a glycophospholipid
membrane anchor . . . . . . . . . . . . 77
M. K. Shaw and
L. G. Tilney and
A. J. Musoke The entry of Theileria parva sporozoites
into bovine lymphocytes: evidence for
MHC class I involvement . . . . . . . . 87
N. Stelly and
J. P. Mauger and
M. Claret and
A. Adoutte Cortical alveoli of Paramecium: a vast
submembranous calcium storage
compartment . . . . . . . . . . . . . . 103
K. Zaar and
A. Völkl and
H. D. Fahimi Purification of marginal plates from
bovine renal peroxisomes: identification
with L-alpha-hydroxyacid oxidase B . . . 113
J. W. Slot and
H. J. Geuze and
S. Gigengack and
G. E. Lienhard and
D. E. James Immuno-localization of the insulin
regulatable glucose transporter in brown
adipose tissue of the rat . . . . . . . 123
P. F. Weller and
S. W. Ryeom and
S. T. Picard and
S. J. Ackerman and
A. M. Dvorak Cytoplasmic lipid bodies of neutrophils:
formation induced by cis-unsaturated
fatty acids and mediated by protein
kinase C . . . . . . . . . . . . . . . . 137
V. Nehls and
D. Drenckhahn Heterogeneity of microvascular pericytes
for smooth muscle type alpha-actin . . . 147
P. A. Janmey and
U. Euteneuer and
P. Traub and
M. Schliwa Viscoelastic properties of vimentin
compared with other filamentous
biopolymer networks . . . . . . . . . . 155
M. R. Paddy and
D. Chelsky Spoke: a 120-kD protein associated with
a novel filamentous structure on or near
kinetochore microtubules in the mitotic
spindle . . . . . . . . . . . . . . . . 161
U. H. Frixen and
J. Behrens and
M. Sachs and
G. Eberle and
B. Voss and
A. Warda and
D. Löchner and
W. Birchmeier E-cadherin-mediated cell--cell adhesion
prevents invasiveness of human carcinoma
cells . . . . . . . . . . . . . . . . . 173
R. P. Mecham and
L. Whitehouse and
M. Hay and
A. Hinek and
M. P. Sheetz Ligand affinity of the 67-kD
elastin/laminin binding protein is
modulated by the protein's lectin
domain: visualization of
elastin/laminin-receptor complexes with
gold-tagged ligands . . . . . . . . . . 187
J. Voorberg and
R. Fontijn and
J. Calafat and
H. Janssen and
J. A. van Mourik and
H. Pannekoek Assembly and routing of von Willebrand
factor variants: the requirements for
disulfide-linked dimerization reside
within the carboxy-terminal 151 amino
acids . . . . . . . . . . . . . . . . . 195
T. A. Brown and
T. Bouchard and
T. St John and
E. Wayner and
W. G. Carter Human keratinocytes express a new CD44
core protein (CD44E) as a
heparan-sulfate intrinsic membrane
proteoglycan with additional exons . . . 207
G. K. Blobel E. B. Wilson medalist, 1990 . . . . . . 223
S. High and
B. Dobberstein The signal sequence interacts with the
methionine-rich domain of the 54-kD
protein of signal recognition particle 229
T. Kobayashi and
Y. Arakawa Transport of exogenous fluorescent
phosphatidylserine analogue to the Golgi
apparatus in cultured fibroblasts . . . 235
H. Nakajima and
A. Hirata and
Y. Ogawa and
T. Yonehara and
K. Yoda and
M. Yamasaki A cytoskeleton-related gene, uso1, is
required for intracellular protein
transport in \bionameSaccharomyces
cerevisiae . . . . . . . . . . . . . . . 245
R. G. Parton and
C. G. Dotti and
R. Bacallao and
I. Kurtz and
K. Simons and
K. Prydz pH-induced microtubule-dependent
redistribution of late endosomes in
neuronal and epithelial cells . . . . . 261
T. Gilbert and
A. Le Bivic and
A. Quaroni and
E. Rodriguez-Boulan Microtubular organization and its
involvement in the biogenetic pathways
of plasma membrane proteins in Caco-2
intestinal epithelial cells . . . . . . 275
M. Eppenberger-Eberhardt and
I. Riesinger and
M. Messerli and
P. Schwarb and
M. Müller and
H. M. Eppenberger and
T. Wallimann Adult rat cardiomyocytes cultured in
creatine-deficient medium display large
mitochondria with paracrystalline
inclusions, enriched for creatine kinase 289
S. Lowey and
G. S. Waller and
E. Bandman Neonatal and adult myosin heavy chains
form homodimers during avian skeletal
muscle development . . . . . . . . . . . 303
B. Kerwin and
E. Bandman Assembly of avian skeletal muscle
myosins: evidence that homodimers of the
heavy chain subunit are the
thermodynamically stable form . . . . . 311
N. Sato and
S. Yonemura and
T. Obinata and
S. Tsukita and
S. Tsukita Radixin, a barbed end-capping
actin-modulating protein, is
concentrated at the cleavage furrow
during cytokinesis . . . . . . . . . . . 321
M. Billger and
E. Strömberg and
M. Wallin Microtubule-associated
proteins-dependent colchicine stability
of acetylated cold-labile brain
microtubules from the Atlantic cod,
Gadus morhua . . . . . . . . . . . . . . 331
D. E. Johnson and
S. K. Dutcher Molecular studies of linkage group XIX
of \bionameChlamydomonas reinhardtii:
evidence against a basal body location 339
V. J. Allan and
R. D. Vale Cell cycle control of microtubule-based
membrane transport and tubule formation
in vitro . . . . . . . . . . . . . . . . 347
B. A. Lee and
D. J. Donoghue Membrane-anchored form of v--sis/PDGF--B
induces mitogenesis without detectable
PDGF receptor autophosphorylation . . . 361
P. P. Mehta and
W. R. Loewenstein Differential regulation of communication
by retinoic acid in homologous and
heterologous junctions between normal
and transformed cells . . . . . . . . . 371
J. E. Collins and
P. K. Legan and
T. P. Kenny and
J. MacGarvie and
J. L. Holton and
D. R. Garrod Cloning and sequence analysis of
desmosomal glycoproteins 2 and 3
(desmocollins): cadherin-like desmosomal
adhesion molecules with heterogeneous
cytoplasmic domains . . . . . . . . . . 381
B. Allinquant and
S. M. Staugaitis and
D. D'Urso and
D. R. Colman The ectopic expression of myelin basic
protein isoforms in Shiverer
oligodendrocytes: implications for
myelinogenesis . . . . . . . . . . . . . 393
I. de Curtis and
V. Quaranta and
R. N. Tamura and
L. F. Reichardt Laminin receptors in the retina:
sequence analysis of the chick integrin
alpha 6 subunit. Evidence for
transcriptional and posttranslational
regulation . . . . . . . . . . . . . . . 405
P. J. Lein and
D. Higgins and
D. C. Turner and
L. A. Flier and
V. P. Terranova The NC1 domain of type IV collagen
promotes axonal growth in sympathetic
neurons through interaction with the
alpha 1 beta 1 integrin . . . . . . . . 417
J. Balsamo and
R. Thiboldeaux and
N. Swaminathan and
J. Lilien Antibodies to the retina
N-acetylgalactosaminylphosphotransferase
modulate N-cadherin-mediated adhesion
and uncouple the N-cadherin transferase
complex from the actin-containing
cytoskeleton . . . . . . . . . . . . . . 429
C. L. Librach and
Z. Werb and
M. L. Fitzgerald and
K. Chiu and
N. M. Corwin and
R. A. Esteves and
D. Grobelny and
R. Galardy and
C. H. Damsky and
S. J. Fisher $ 92$-kD type IV collagenase mediates
invasion of human cytotrophoblasts . . . 437
N. Kieffer and
L. A. Fitzgerald and
D. Wolf and
D. A. Cheresh and
D. R. Phillips Adhesive properties of the beta 3
integrins: comparison of GP IIb--IIIa
and the vitronectin receptor
individually expressed in human melanoma
cells . . . . . . . . . . . . . . . . . 451
Z. A. Wu and
C. Murphy and
H. G. Callan and
J. G. Gall Small nuclear ribonucleoproteins and
heterogeneous nuclear ribonucleoproteins
in the amphibian germinal vesicle:
loops, spheres, and snurposomes . . . . 465
E. Heitlinger and
M. Peter and
M. Häner and
A. Lustig and
U. Aebi and
E. A. Nigg Expression of chicken lamin B2 in
\bionameEscherichia coli:
characterization of its structure,
assembly, and molecular interactions . . 485
D. Aubert and
M. Garcia and
M. Benchaibi and
D. Poncet and
Y. Chebloune and
G. Verdier and
V. Nigon and
J. Samarut and
C. V. Mura Inhibition of proliferation of primary
avian fibroblasts through expression of
histone H5 depends on the degree of
phosphorylation of the protein . . . . . 497
L. M. Roy and
K. I. Swenson and
D. H. Walker and
B. G. Gabrielli and
R. S. Li and
H. Piwnica-Worms and
J. L. Maller Activation of p34cdc2 kinase by cyclin A 507
A. Puoti and
C. Desponds and
A. Conzelmann Biosynthesis of
mannosylinositolphosphoceramide in
\bionameSaccharomyces cerevisiae is
dependent on genes controlling the flow
of secretory vesicles from the
endoplasmic reticulum to the Golgi . . . 515
K. Redding and
C. Holcomb and
R. S. Fuller Immunolocalization of Kex2 protease
identifies a putative late Golgi
compartment in the yeast
\bionameSaccharomyces cerevisiae . . . . 527
G. C. Johnston and
J. A. Prendergast and
R. A. Singer The \bionameSaccharomyces cerevisiae
MYO2 gene encodes an essential myosin
for vectorial transport of vesicles . . 539
K. Sandvig and
K. Prydz and
M. Ryd and
B. van Deurs Endocytosis and intracellular transport
of the glycolipid-binding ligand Shiga
toxin in polarized MDCK cells . . . . . 553
R. J. Levine and
P. D. Chantler and
R. W. Kensler and
J. L. Woodhead Effects of phosphorylation by myosin
light chain kinase on the structure of
Limulus thick filaments . . . . . . . . 563
R. J. Levine and
J. L. Woodhead and
H. A. King The effect of calcium activation of
skinned fiber bundles on the structure
of Limulus thick filaments . . . . . . . 573
E. M. McNally and
M. M. Bravo-Zehnder and
L. A. Leinwand Identification of sequences necessary
for the association of cardiac myosin
subunits . . . . . . . . . . . . . . . . 585
L. Solnica-Krezel and
T. G. Burland and
W. F. Dove Variable pathways for developmental
changes of mitosis and cytokinesis in
Physarum polycephalum . . . . . . . . . 591
M. J. Schibler and
B. Huang The colR4 and colR15 beta-tubulin
mutations in \bionameChlamydomonas
reinhardtii confer altered sensitivities
to microtubule inhibitors and herbicides
by enhancing microtubule stability . . . 605
H. Sakakibara and
D. R. Mitchell and
R. Kamiya A \bionameChlamydomonas outer arm dynein
mutant missing the alpha heavy chain . . 615
A. F. Ross and
W. N. Green and
D. S. Hartman and
T. Claudio Efficiency of acetylcholine receptor
subunit assembly and its regulation by
cAMP . . . . . . . . . . . . . . . . . . 623
P. C. Begovac and
D. E. Hall and
B. D. Shur Laminin fragment E8 mediates PC12 cell
neurite outgrowth by binding to cell
surface beta 1,4 galactosyltransferase 637
M. Pasdar and
K. A. Krzeminski and
W. J. Nelson Regulation of desmosome assembly in MDCK
epithelial cells: coordination of
membrane core and cytoplasmic plaque
domain assembly at the plasma membrane 645
R. G. Fehon and
K. Johansen and
I. Rebay and
S. Artavanis-Tsakonas Complex cellular and subcellular
regulation of notch expression during
embryonic and imaginal development of
\bionameDrosophila: implications for
notch function . . . . . . . . . . . . . 657
C. L. Rawson and
D. T. Loo and
J. R. Duimstra and
O. R. Hedstrom and
E. E. Schmidt and
D. W. Barnes Death of serum-free mouse embryo cells
caused by epidermal growth factor
deprivation . . . . . . . . . . . . . . 671
A. Yamaguchi and
T. Katagiri and
T. Ikeda and
J. M. Wozney and
V. Rosen and
E. A. Wang and
A. J. Kahn and
T. Suda and
S. Yoshiki Recombinant human bone morphogenetic
protein-2 stimulates osteoblastic
maturation and inhibits myogenic
differentiation in vitro . . . . . . . . 681
M. Desjardins and
M. Bendayan Ontogenesis of glomerular basement
membrane: structural and functional
properties . . . . . . . . . . . . . . . 689
U. Fischer and
E. Darzynkiewicz and
S. M. Tahara and
N. A. Dathan and
R. Lührmann and
I. W. Mattaj Diversity in the signals required for
nuclear accumulation of U snRNPs and
variety in the pathways of nuclear
transport . . . . . . . . . . . . . . . 705
R. P. Jansen and
E. C. Hurt and
H. Kern and
H. Lehtonen and
M. Carmo-Fonseca and
B. Lapeyre and
D. Tollervey Evolutionary conservation of the human
nucleolar protein fibrillarin and its
functional expression in yeast . . . . . 715
S. H. Hansen and
K. Sandvig and
B. van Deurs The preendosomal compartment comprises
distinct coated and noncoated endocytic
vesicle populations . . . . . . . . . . 731
T. Kobayashi and
J. M. Robinson A novel intracellular compartment with
unusual secretory properties in human
neutrophils . . . . . . . . . . . . . . 743
S. Greenberg and
J. el Khoury and
F. di Virgilio and
E. M. Kaplan and
S. C. Silverstein Ca$^{(2 +)}$-independent F-actin
assembly and disassembly during Fc
receptor-mediated phagocytosis in mouse
macrophages . . . . . . . . . . . . . . 757
T. Whalley and
I. Crossley and
M. Whitaker Phosphoprotein inhibition of
calcium-stimulated exocytosis in sea
urchin eggs . . . . . . . . . . . . . . 769
A. Villa and
P. Podini and
D. O. Clegg and
T. Pozzan and
J. Meldolesi Intracellular Ca$^{2+}$ stores in
chicken Purkinje neurons: differential
distribution of the low affinity-high
capacity Ca$^{2+}$ binding protein,
calsequestrin, of Ca$^{2+}$ ATPase and
of the ER lumenal protein, Bip . . . . . 779
J. L. Sutko and
J. A. Airey and
K. Murakami and
M. Takeda and
C. Beck and
T. Deerinck and
M. H. Ellisman Foot protein isoforms are expressed at
different times during embryonic chick
skeletal muscle development . . . . . . 793
S. P. Alexander and
C. L. Rieder Chromosome motion during attachment to
the vertebrate spindle: initial
saltatory-like behavior of chromosomes
and quantitative analysis of force
production by nascent kinetochore fibers 805
B. D. Wright and
J. H. Henson and
K. P. Wedaman and
P. J. Willy and
J. N. Morand and
J. M. Scholey Subcellular localization and sequence of
sea urchin kinesin heavy chain: evidence
for its association with membranes in
the mitotic apparatus and interphase
cytoplasm . . . . . . . . . . . . . . . 817
D. R. Mitchell and
Y. Kang Identification of oda6 as a
\bionameChlamydomonas dynein mutant by
rescue with the wild-type gene . . . . . 835
R. K. Miller and
K. Vikstrom and
R. D. Goldman Keratin incorporation into intermediate
filament networks is a rapid process . . 843
A. Dvir and
Y. Milner and
O. Chomsky and
C. Gilon and
A. Gazit and
A. Levitzki The inhibition of EGF-dependent
proliferation of keratinocytes by
tyrphostin tyrosine kinase blockers . . 857
S. Tsukita and
K. Oishi and
T. Akiyama and
Y. Yamanashi and
T. Yamamoto and
S. Tsukita Specific proto-oncogenic tyrosine
kinases of src family are enriched in
cell-to-cell adherens junctions where
the level of tyrosine phosphorylation is
elevated . . . . . . . . . . . . . . . . 867
J. Kartenbeck and
M. Schmelz and
W. W. Franke and
B. Geiger Endocytosis of junctional cadherins in
bovine kidney epithelial (MDBK) cells
cultured in low Ca$^{2+}$ ion medium . . 881
E. W. Napolitano and
K. Venstrom and
E. F. Wheeler and
L. F. Reichardt Molecular cloning and characterization
of B-cadherin, a novel chick cadherin 893
A. Sonnenberg and
J. Calafat and
H. Janssen and
H. Daams and
L. M. van der Raaij-Helmer and
R. Falcioni and
S. J. Kennel and
J. D. Aplin and
J. Baker and
M. Loizidou Integrin alpha 6/beta 4 complex is
located in hemidesmosomes, suggesting a
major role in epidermal cell-basement
membrane adhesion . . . . . . . . . . . 907
E. A. Wayner and
R. A. Orlando and
D. A. Cheresh Integrins alpha v beta 3 and alpha v
beta 5 contribute to cell attachment to
vitronectin but differentially
distribute on the cell surface . . . . . 919
S. L. Goodman and
M. Aumailley and
H. von der Mark Multiple cell surface receptors for the
short arms of laminin: alpha 1 beta 1
integrin and RGD-dependent proteins
mediate cell attachment only to domains
III in murine tumor laminin . . . . . . 931
J. Gil and
T. Higgins and
E. Rozengurt Mastoparan, a novel mitogen for Swiss
3T3 cells, stimulates pertussis
toxin-sensitive arachidonic acid release
without inositol phosphate accumulation 943
D. Prié and
P. M. Ronco and
B. Baudouin and
M. Géniteau-Legendre and
M. Antoine and
R. Piedagnel and
S. Estrade and
B. Lelongt and
P. J. Verroust and
R. Cassingéna Activation of the simian virus 40 (SV40)
genome abrogates sensitivity to AVP in a
rabbit collecting tubule cell line by
repressing membrane expression of AVP
receptors . . . . . . . . . . . . . . . 951
G. P. Lunstrum and
N. P. Morris and
A. M. McDonough and
D. R. Keene and
R. E. Burgeson Identification and partial
characterization of two type XII-like
collagen molecules . . . . . . . . . . . 963
D. R. Keene and
G. P. Lunstrum and
N. P. Morris and
D. W. Stoddard and
R. E. Burgeson Two type XII-like collagens localize to
the surface of banded collagen fibrils 971
C. Nathan and
M. Sporn Cytokines in context . . . . . . . . . . 981
D. Quinn and
L. Orci and
M. Ravazzola and
H. P. Moore Intracellular transport and sorting of
mutant human proinsulins that fail to
form hexamers . . . . . . . . . . . . . 987
L. Wikström and
H. F. Lodish Nonlysosomal, pre-Golgi degradation of
unassembled asialoglycoprotein receptor
subunits: a TLCK- and TPCK-sensitive
cleavage within the ER . . . . . . . . . 997
N. T. Ktistakis and
M. G. Roth and
G. S. Bloom PtK1 cells contain a nondiffusible,
dominant factor that makes the Golgi
apparatus resistant to brefeldin A . . . 1009
H. Stenmark and
J. O. Moskaug and
I. H. Madshus and
K. Sandvig and
S. Olsnes Peptides fused to the amino-terminal end
of diphtheria toxin are translocated to
the cytosol . . . . . . . . . . . . . . 1025
A. F. Cowman and
S. Karcz and
D. Galatis and
J. G. Culvenor A P-glycoprotein homologue of Plasmodium
falciparum is localized on the digestive
vacuole . . . . . . . . . . . . . . . . 1033
P. K. Luther Three-dimensional reconstruction of a
simple Z-band in fish muscle . . . . . . 1043
M. L. Vitale and
A. Rodríguez Del Castillo and
L. Tchakarov and
J. M. Trifaró Cortical filamentous actin disassembly
and scinderin redistribution during
chromaffin cell stimulation precede
exocytosis, a phenomenon not exhibited
by gelsolin . . . . . . . . . . . . . . 1057
N. Watanabe and
N. Tsukada and
C. R. Smith and
M. J. Phillips Motility of bile canaliculi in the
living animal: implications for bile
flow . . . . . . . . . . . . . . . . . . 1069
P. J. Goldschmidt-Clermont and
L. M. Machesky and
S. K. Doberstein and
T. D. Pollard Mechanism of the interaction of human
platelet profilin with actin . . . . . . 1081
R. P. Zinkowski and
J. Meyne and
B. R. Brinkley The centromere-kinetochore complex: a
repeat subunit model . . . . . . . . . . 1091
M. B. McCormick and
P. A. Coulombe and
E. Fuchs Sorting out IF networks: consequences of
domain swapping on IF recognition and
assembly . . . . . . . . . . . . . . . . 1111
P. Blount and
J. P. Merlie BIP associates with newly synthesized
subunits of the mouse muscle nicotinic
receptor . . . . . . . . . . . . . . . . 1125
R. Sealock and
M. H. Butler and
N. R. Kramarcy and
K. X. Gao and
A. A. Murnane and
K. Douville and
S. C. Froehner Localization of dystrophin relative to
acetylcholine receptor domains in
electric tissue and adult and cultured
skeletal muscle . . . . . . . . . . . . 1133
P. D. Walton and
J. A. Airey and
J. L. Sutko and
C. F. Beck and
G. A. Mignery and
T. C. Südhof and
T. J. Deerinck and
M. H. Ellisman Ryanodine and inositol trisphosphate
receptors coexist in avian cerebellar
Purkinje neurons . . . . . . . . . . . . 1145
A. Lochter and
L. Vaughan and
A. Kaplony and
A. Prochiantz and
M. Schachner and
A. Faissner J1\slash tenascin in substrate-bound and
soluble form displays contrary effects
on neurite outgrowth . . . . . . . . . . 1159
R. J. Scheibe and
D. D. Ginty and
J. A. Wagner Retinoic acid stimulates the
differentiation of PC12 cells that are
deficient in cAMP-dependent protein
kinase . . . . . . . . . . . . . . . . . 1173
D. C. Rubin and
K. A. Roth and
E. H. Birkenmeier and
J. I. Gordon Epithelial cell differentiation in
normal and transgenic mouse intestinal
isografts . . . . . . . . . . . . . . . 1183
P. Mignatti and
R. Mazzieri and
D. B. Rifkin Expression of the urokinase receptor in
vascular endothelial cells is stimulated
by basic fibroblast growth factor . . . 1193
Y. Shimizu and
W. Newman and
T. V. Gopal and
K. J. Horgan and
N. Graber and
L. D. Beall and
G. A. van Seventer and
S. Shaw Four molecular pathways of T cell
adhesion to endothelial cells: roles of
LFA-1, VCAM-1, and ELAM-1 and changes in
pathway hierarchy under different
activation conditions . . . . . . . . . 1203
Y. Imai and
M. S. Singer and
C. Fennie and
L. A. Lasky and
S. D. Rosen Identification of a carbohydrate-based
endothelial ligand for a lymphocyte
homing receptor . . . . . . . . . . . . 1213
F. Pagani and
L. Zagato and
C. Vergani and
G. Casari and
A. Sidoli and
F. E. Baralle Tissue-specific splicing pattern of
fibronectin messenger RNA precursor
during development and aging in rat . . 1223
C. J. Soroka and
M. G. Farquhar Characterization of a novel heparan
sulfate proteoglycan found in the
extracellular matrix of liver sinusoids
and basement membranes . . . . . . . . . 1231
U. Stochaj and
M. Osborne and
T. Kurihara and
P. Silver A yeast protein that binds nuclear
localization signals: purification
localization, and antibody inhibition of
binding activity . . . . . . . . . . . . 1243
E. Bober and
G. E. Lyons and
T. Braun and
G. Cossu and
M. Buckingham and
H. H. Arnold The muscle regulatory gene, Myf-6, has a
biphasic pattern of expression during
early mouse development . . . . . . . . 1255
R. E. Pagano and
O. C. Martin and
H. C. Kang and
R. P. Haugland A novel fluorescent ceramide analogue
for studying membrane traffic in animal
cells: accumulation at the Golgi
apparatus results in altered spectral
properties of the sphingolipid precursor 1267
D. Deretic and
D. S. Papermaster Polarized sorting of rhodopsin on
post-Golgi membranes in frog retinal
photoreceptor cells . . . . . . . . . . 1281
G. Knoll and
C. Braun and
H. Plattner Quenched flow analysis of exocytosis in
Paramecium cells: time course, changes
in membrane structure, and calcium
requirements revealed after rapid mixing
and rapid freezing of intact cells . . . 1295
H. Hòyvik and
P. B. Gordon and
T. O. Berg and
P. E. Stròmhaug and
P. O. Seglen Inhibition of autophagic-lysosomal
delivery and autophagic lactolysis by
asparagine . . . . . . . . . . . . . . . 1305
R. J. Duronio and
D. A. Rudnick and
R. L. Johnson and
D. R. Johnson and
J. I. Gordon Myristic acid auxotrophy caused by
mutation of S. cerevisiae
myristoyl--CoA: protein
N-myristoyltransferase . . . . . . . . . 1313
J. D. Cortese and
A. L. Voglino and
C. R. Hackenbrock Ionic strength of the intermembrane
space of intact mitochondria as
estimated with fluorescein--BSA
delivered by low pH fusion . . . . . . . 1331
F. Grohovaz and
D. Zacchetti and
E. Clementi and
P. Lorenzon and
J. Meldolesi and
G. Fumagalli [Ca$^{2+}$]i imaging in PC12 cells:
multiple response patterns to receptor
activation reveal new aspects of
transmembrane signaling . . . . . . . . 1341
J. A. DePasquale and
C. S. Izzard Accumulation of talin in nodes at the
edge of the lamellipodium and separate
incorporation into adhesion plaques at
focal contacts in fibroblasts . . . . . 1351
F. Tournier and
S. Komesli and
M. Paintrand and
D. Job and
M. Bornens The intercentriolar linkage is critical
for the ability of heterologous
centrosomes to induce parthenogenesis in
\bionameXenopus . . . . . . . . . . . . 1361
H. L. Paulson and
A. F. Ross and
W. N. Green and
T. Claudio Analysis of early events in
acetylcholine receptor assembly . . . . 1371
J. Weis and
S. M. Fine and
C. David and
S. Savarirayan and
J. R. Sanes Integration site-dependent expression of
a transgene reveals specialized features
of cells associated with neuromuscular
junctions . . . . . . . . . . . . . . . 1385
M. Grumet and
V. Mauro and
M. P. Burgoon and
G. M. Edelman and
B. A. Cunningham Structure of a new nervous system
glycoprotein, Nr--CAM, and its
relationship to subgroups of neural cell
adhesion molecules . . . . . . . . . . . 1399
R. R. Schleef and
D. J. Loskutoff and
T. J. Podor Immunoelectron microscopic localization
of type 1 plasminogen activator
inhibitor on the surface of activated
endothelial cells . . . . . . . . . . . 1413
S. Goerdt and
L. J. Walsh and
G. F. Murphy and
J. S. Pober Identification of a novel high molecular
weight protein preferentially expressed
by sinusoidal endothelial cells in
normal human tissues . . . . . . . . . . 1425
S. Kojima and
P. C. Harpel and
D. B. Rifkin Lipoprotein (a) inhibits the generation
of transforming growth factor beta: an
endogenous inhibitor of smooth muscle
cell migration . . . . . . . . . . . . . 1439
S. A. Rogers and
G. Ryan and
M. R. Hammerman Insulin-like growth factors I and II are
produced in the metanephros and are
required for growth and development in
vitro . . . . . . . . . . . . . . . . . 1447
A. Mauviel and
F. Rédini and
D. J. Hartmann and
J. P. Pujol and
C. H. Evans Modulation of human dermal fibroblast
extracellular matrix metabolism by the
lymphokine leukoregulin . . . . . . . . 1455
J. E. Schwarzbauer Identification of the fibronectin
sequences required for assembly of a
fibrillar matrix . . . . . . . . . . . . 1463
P. Vandenberg and
A. Kern and
A. Ries and
L. Luckenbill-Edds and
K. Mann and
K. Kühn Characterization of a type IV collagen
major cell binding site with affinity to
the alpha 1 beta 1 and the alpha 2 beta
1 integrins . . . . . . . . . . . . . . 1475
S. C. Froehner The submembrane machinery for nicotinic
acetylcholine receptor clustering . . . 1
M. E. Walmsley and
R. S. Buckle and
J. Allan and
R. K. Patient A chicken red cell inhibitor of
transcription associated with the
terminally differentiated state . . . . 9
K. V. Kellaris and
S. Bowen and
R. Gilmore ER translocation intermediates are
adjacent to a nonglycosylated 34-kD
integral membrane protein . . . . . . . 21
P. A. Schweitzer and
S. E. Taylor and
L. D. Shultz Synthesis of abnormal immunoglobulins by
hybridomas from autoimmune ``viable
motheaten'' mutant mice . . . . . . . . 35
H. Hausser and
H. Kresse Binding of heparin and of the small
proteoglycan decorin to the same
endocytosis receptor proteins leads to
different metabolic consequences . . . . 45
D. A. Jans and
R. Peters and
P. Jans and
F. Fahrenholz Vasopressin V2-receptor mobile fraction
and ligand-dependent adenylate cyclase
activity are directly correlated in
LLC--PK1 renal epithelial cells . . . . 53
S. Mayor and
A. K. Menon and
G. A. Cross Transfer of
glycosyl-phosphatidylinositol membrane
anchors to polypeptide acceptors in a
cell-free system . . . . . . . . . . . . 61
R. A. Walker and
N. K. Pryer and
E. D. Salmon Dilution of individual microtubules
observed in real time in vitro: evidence
that cap size is small and independent
of elongation rate . . . . . . . . . . . 73
G. Wiche and
B. Becker and
K. Luber and
G. Weitzer and
M. J. Castañon and
R. Hauptmann and
C. Stratowa and
M. Stewart Cloning and sequencing of rat plectin
indicates a 466-kD polypeptide chain
with a three-domain structure based on a
central alpha-helical coiled coil . . . 83
M. H. Valdivieso and
P. C. Mol and
J. A. Shaw and
E. Cabib and
A. Durán CAL1, a gene required for activity of
chitin synthase 3 in
\bionameSaccharomyces cerevisiae . . . . 101
J. A. Shaw and
P. C. Mol and
B. Bowers and
S. J. Silverman and
M. H. Valdivieso and
A. Durán and
E. Cabib The function of chitin synthases 2 and 3
in the \bionameSaccharomyces cerevisiae
cell cycle . . . . . . . . . . . . . . . 111
V. Witzemann and
H. R. Brenner and
B. Sakmann Neural factors regulate AChR subunit
mRNAs at rat neuromuscular synapses . . 125
A. Acheson and
J. L. Sunshine and
U. Rutishauser NCAM polysialic acid can regulate both
cell--cell and cell-substrate
interactions . . . . . . . . . . . . . . 143
H. Zhang and
N. N. Desai and
A. Olivera and
T. Seki and
G. Brooker and
S. Spiegel Sphingosine-$1$-phosphate, a novel
lipid, involved in cellular
proliferation . . . . . . . . . . . . . 155
D. R. Finlay and
E. Meier and
P. Bradley and
J. Horecka and
D. J. Forbes A complex of nuclear pore proteins
required for pore function . . . . . . . 169
C. K. Suzuki and
J. S. Bonifacino and
A. Y. Lin and
M. M. Davis and
R. D. Klausner Regulating the retention of T-cell
receptor alpha chain variants within the
endoplasmic reticulum: Ca(2+)-dependent
association with BiP . . . . . . . . . . 189
T. R. Graham and
S. D. Emr Compartmental organization of
Golgi-specific protein modification and
vacuolar protein sorting events defined
in a yeast sec18 (NSF) mutant . . . . . 207
M. F. Rexach and
R. W. Schekman Distinct biochemical requirements for
the budding, targeting, and fusion of
ER-derived transport vesicles . . . . . 219
J. W. Kok and
T. Babia and
D. Hoekstra Sorting of sphingolipids in the
endocytic pathway of HT29 cells . . . . 231
E. Otto and
M. Kunimoto and
T. McLaughlin and
V. Bennett Isolation and characterization of cDNAs
encoding human brain ankyrins reveal a
family of alternatively spliced genes 241
T. Miron and
K. Vancompernolle and
J. Vandekerckhove and
M. Wilchek and
B. Geiger A 25-kD inhibitor of actin
polymerization is a low molecular mass
heat shock protein . . . . . . . . . . . 255
G. A. Hastings and
C. P. Emerson Myosin functional domains encoded by
alternative exons are expressed in
specific thoracic muscles of
\bionameDrosophila . . . . . . . . . . . 263
A. K. Wilson and
G. Gorgas and
W. D. Claypool and
P. de Lanerolle An increase or a decrease in myosin II
phosphorylation inhibits macrophage
motility . . . . . . . . . . . . . . . . 277
L. Wordeman and
E. R. Steuer and
M. P. Sheetz and
T. Mitchison Chemical subdomains within the
kinetochore domain of isolated CHO
mitotic chromosomes . . . . . . . . . . 285
N. Hirokawa and
R. Sato-Yoshitake and
N. Kobayashi and
K. K. Pfister and
G. S. Bloom and
S. T. Brady Kinesin associates with anterogradely
transported membranous organelles in
vivo . . . . . . . . . . . . . . . . . . 295
A. R. Marks and
M. B. Taubman and
A. Saito and
Y. Dai and
S. Fleischer The ryanodine receptor/junctional
channel complex is regulated by growth
factors in a myogenic cell line . . . . 303
A. F. Sikorski and
G. Terlecki and
I. S. Zagon and
S. R. Goodman Synapsin I-mediated interaction of brain
spectrin with synaptic vesicles . . . . 313
W. C. Chen and
B. Obrink Cell--cell contacts mediated by
E-cadherin (uvomorulin) restrict
invasive behavior of L-cells . . . . . . 319
I. Daar and
R. S. Paules and
G. F. Vande Woude A characterization of cytostatic factor
activity from \bionameXenopus eggs and
c-mos-transformed cells . . . . . . . . 329
R. Panet and
H. Atlan Stimulation of bumetanide-sensitive
Na+/K+/Cl-cotransport by different
mitogens in synchronized human skin
fibroblasts is essential for cell
proliferation . . . . . . . . . . . . . 337
E. L. Berg and
M. K. Robinson and
R. A. Warnock and
E. C. Butcher The human peripheral lymph node vascular
addressin is a ligand for LECAM-1, the
peripheral lymph node homing receptor 343
G. S. Kansas and
O. Spertini and
L. M. Stoolman and
T. F. Tedder Molecular mapping of functional domains
of the leukocyte receptor for
endothelium, LAM-1 . . . . . . . . . . . 351
A. Nishiyama and
K. J. Dahlin and
J. T. Prince and
S. R. Johnstone and
W. B. Stallcup The primary structure of NG2, a novel
membrane-spanning proteoglycan . . . . . 359
K. Turksen and
J. E. Aubin Positive and negative immunoselection
for enrichment of two classes of
osteoprogenitor cells . . . . . . . . . 373
S. M. Bailer and
H. M. Eppenberger and
G. Griffiths and
E. A. Nigg Characterization of A 54-kD protein of
the inner nuclear membrane: evidence for
cell cycle-dependent interaction with
the nuclear lamina . . . . . . . . . . . 389
I. Braakman and
H. Hoover-Litty and
K. R. Wagner and
A. Helenius Folding of influenza hemagglutinin in
the endoplasmic reticulum . . . . . . . 401
C. B. Brewer and
M. G. Roth A single amino acid change in the
cytoplasmic domain alters the polarized
delivery of influenza virus
hemagglutinin . . . . . . . . . . . . . 413
C. Fuhrer and
I. Geffen and
M. Spiess Endocytosis of the ASGP receptor H1 is
reduced by mutation of tyrosine-5 but
still occurs via coated pits . . . . . . 423
K. A. Haines and
J. Reibman and
X. Y. Tang and
M. Blake and
G. Weissmann Effects of protein I of Neisseria
gonorrhoeae on neutrophil activation:
generation of diacylglycerol from
phosphatidylcholine via a specific
phospholipase C is associated with
exocytosis . . . . . . . . . . . . . . . 433
K. U. Fröhlich and
H. W. Fries and
M. Rüdiger and
R. Erdmann and
D. Botstein and
D. Mecke Yeast cell cycle protein CDC48p shows
full-length homology to the mammalian
protein VCP and is a member of a protein
family involved in secretion, peroxisome
formation, and gene expression . . . . . 443
A. B. Peter and
J. C. Schittny and
V. Niggli and
H. Reuter and
E. Sigel The polarized distribution of
poly(A+)-mRNA-induced functional ion
channels in the \bionameXenopus oocyte
plasma membrane is prevented by
anticytoskeletal drugs . . . . . . . . . 455
R. Francis and
R. H. Waterston Muscle cell attachment in
\bionameCaenorhabditis elegans . . . . . 465
F. M. Pavalko and
K. Burridge Disruption of the actin cytoskeleton
after microinjection of proteolytic
fragments of alpha-actinin . . . . . . . 481
G. Albrecht-Buehler Surface extensions of 3T3 cells towards
distant infrared light sources . . . . . 493
M. H. Symons and
T. J. Mitchison Control of actin polymerization in live
and permeabilized fibroblasts . . . . . 503
M. Snyder and
S. Gehrung and
B. D. Page Studies concerning the temporal and
genetic control of cell polarity in
\bionameSaccharomyces cerevisiae . . . . 515
J. B. Welsh and
G. N. Gill and
M. G. Rosenfeld and
A. Wells A negative feedback loop attenuates
EGF-induced morphological changes . . . 533
W. M. Jongen and
D. J. Fitzgerald and
M. Asamoto and
C. Piccoli and
T. J. Slaga and
D. Gros and
M. Takeichi and
H. Yamasaki Regulation of connexin $ 43$-mediated
gap junctional intercellular
communication by Ca$^{2+}$ in mouse
epidermal cells is controlled by
E-cadherin . . . . . . . . . . . . . . . 545
K. Miyake and
K. Medina and
K. Ishihara and
M. Kimoto and
R. Auerbach and
P. W. Kincade A VCAM-like adhesion molecule on murine
bone marrow stromal cells mediates
binding of lymphocyte precursors in
culture . . . . . . . . . . . . . . . . 557
P. Rousselle and
G. P. Lunstrum and
D. R. Keene and
R. E. Burgeson Kalinin: an epithelium-specific basement
membrane adhesion molecule that is a
component of anchoring filaments . . . . 567
B. Fournier and
P. A. Price Characterization of a new human
osteosarcoma cell line OHS-4 . . . . . . 577
K. Elenius and
S. Vainio and
M. Laato and
M. Salmivirta and
I. Thesleff and
M. Jalkanen Induced expression of syndecan in
healing wounds . . . . . . . . . . . . . 585
A. P. Kwan and
C. E. Cummings and
J. A. Chapman and
M. E. Grant Macromolecular organization of chicken
type X collagen in vitro . . . . . . . . 597
A. J. Caplan and
M. G. Douglas Characterization of YDJ1: a yeast
homologue of the bacterial dnaJ protein 609
M. M. Luke and
A. Sutton and
K. T. Arndt Characterization of SIS1, a
\bionameSaccharomyces cerevisiae
homologue of bacterial dnaJ proteins . . 623
P. G. Collins and
R. Gilmore Ribosome binding to the endoplasmic
reticulum: a 180-kD protein identified
by crosslinking to membrane-bound
ribosomes is not required for ribosome
binding activity . . . . . . . . . . . . 639
M. S. Poruchynsky and
D. R. Maass and
P. H. Atkinson Calcium depletion blocks the maturation
of rotavirus by altering the
oligomerization of virus-encoded
proteins in the ER . . . . . . . . . . . 651
C. d'Enfert and
L. J. Wuestehube and
T. Lila and
R. Schekman Sec12p-dependent membrane binding of the
small GTP-binding protein Sar1p promotes
formation of transport vesicles from the
ER . . . . . . . . . . . . . . . . . . . 663
T. Oka and
S. Nishikawa and
A. Nakano Reconstitution of GTP-binding Sar1
protein function in ER to Golgi
transport . . . . . . . . . . . . . . . 671
S. E. Clark and
G. K. Lamppa Determinants for cleavage of the
chlorophyll a/b binding protein
precursor: a requirement for a basic
residue that is not universal for
chloroplast imported proteins . . . . . 681
P. M. Haney and
J. W. Slot and
R. C. Piper and
D. E. James and
M. Mueckler Intracellular targeting of the
insulin-regulatable glucose transporter
(GLUT4) is isoform specific and
independent of cell type . . . . . . . . 689
D. A. Winkelmann and
T. S. Baker and
I. Rayment Three-dimensional structure of myosin
subfragment-1 from electron microscopy
of sectioned crystals . . . . . . . . . 701
R. J. Barstead and
R. H. Waterston Vinculin is essential for muscle
function in the nematode . . . . . . . . 715
J. Knops and
K. S. Kosik and
G. Lee and
J. D. Pardee and
L. Cohen-Gould and
L. McConlogue Overexpression of tau in a nonneuronal
cell induces long cellular processes . . 725
B. Brugg and
A. Matus Phosphorylation determines the binding
of microtubule-associated protein 2
(MAP2) to microtubules in living cells 735
M. Winey and
L. Goetsch and
P. Baum and
B. Byers MPS1 and MPS2: novel yeast genes
defining distinct steps of spindle pole
body duplication . . . . . . . . . . . . 745
H. Kobayashi and
J. Minshull and
C. Ford and
R. Golsteyn and
R. Poon and
T. Hunt On the synthesis and destruction of A-
and B-type cyclins during oogenesis and
meiotic maturation in \bionameXenopus
laevis . . . . . . . . . . . . . . . . . 755
J. Minshull and
A. Murray and
A. Colman and
T. Hunt \bionameXenopus oocyte maturation does
not require new cyclin synthesis . . . . 767
P. D. Kouklis and
T. Papamarcaki and
A. Merdes and
S. D. Georgatos A potential role for the COOH-terminal
domain in the lateral packing of type
III intermediate filaments . . . . . . . 773
M. W. Klymkowsky and
L. A. Maynell and
C. Nislow Cytokeratin phosphorylation, cytokeratin
filament severing and the solubilization
of the maternal mRNA Vg1 . . . . . . . . 787
Y. Gu and
J. R. Forsayeth and
S. Verrall and
X. M. Yu and
Z. W. Hall Assembly of the mammalian muscle
acetylcholine receptor in transfected
COS cells . . . . . . . . . . . . . . . 799
T. B. Vaidya and
C. M. Weyman and
D. Teegarden and
C. L. Ashendel and
E. J. Taparowsky Inhibition of myogenesis by the H-ras
oncogene: implication of a role for
protein kinase C . . . . . . . . . . . . 809
K. J. Musil and
A. Malmström and
J. Donnér Alteration of proteoglycan metabolism
during the differentiation of 3T3-L1
fibroblasts into adipocytes . . . . . . 821
X. Sha and
L. Yang and
L. E. Gentry Identification and analysis of discrete
functional domains in the pro region of
pre-pro-transforming growth factor beta
1 . . . . . . . . . . . . . . . . . . . 827
D. Schubert and
H. Kimura Substratum-growth factor collaborations
are required for the mitogenic
activities of activin and FGF on
embryonal carcinoma cells . . . . . . . 841
B. S. Weeks and
M. E. Klotman and
S. Dhawan and
M. Kibbey and
J. Rappaport and
H. K. Kleinman and
K. M. Yamada and
P. E. Klotman HIV-1 infection of human T lymphocytes
results in enhanced alpha 5 beta 1
integrin expression . . . . . . . . . . 847
P. Defilippi and
V. van Hinsbergh and
A. Bertolotto and
P. Rossino and
L. Silengo and
G. Tarone Differential distribution and modulation
of expression of alpha 1/beta 1 integrin
on human endothelial cells . . . . . . . 855
S. L. Schmid and
E. Smythe Stage-specific assays for coated pit
formation and coated vesicle budding in
vitro . . . . . . . . . . . . . . . . . 869
H. C. Lin and
M. S. Moore and
D. A. Sanan and
R. G. Anderson Reconstitution of clathrin-coated pit
budding from plasma membranes . . . . . 881
G. A. Keller and
S. Krisans and
S. J. Gould and
J. M. Sommer and
C. C. Wang and
W. Schliebs and
W. Kunau and
S. Brody and
S. Subramani Evolutionary conservation of a microbody
targeting signal that targets proteins
to peroxisomes, glyoxysomes, and
glycosomes . . . . . . . . . . . . . . . 893
B. Baldan and
J. Girard-Bascou and
F. A. Wollman and
J. Olive Evidence for thylakoid membrane fusion
during zygote formation in
\bionameChlamydomonas reinhardtii . . . 905
J. A. Petruszak and
C. L. Nehme and
J. R. Bartles Endoproteolytic cleavage in the
extracellular domain of the integral
plasma membrane protein CE9 precedes its
redistribution from the posterior to the
anterior tail of the rat spermatozoon
during epididymal maturation . . . . . . 917
M. Terasaki and
L. A. Jaffe Organization of the sea urchin egg
endoplasmic reticulum and its
reorganization at fertilization . . . . 929
C. J. Beall and
E. Fyrberg Muscle abnormalities in
\bionameDrosophila melanogaster heldup
mutants are caused by missing or
aberrant troponin--I isoforms . . . . . 941
T. Schultheiss and
Z. X. Lin and
H. Ishikawa and
I. Zamir and
C. J. Stoeckert and
H. Holtzer Desmin\slash vimentin intermediate
filaments are dispensable for many
aspects of myogenesis . . . . . . . . . 953
D. J. Fishkind and
L. G. Cao and
Y. L. Wang Microinjection of the catalytic fragment
of myosin light chain kinase into
dividing cells: effects on mitosis and
cytokinesis . . . . . . . . . . . . . . 967
E. M. Mandelkow and
E. Mandelkow and
R. A. Milligan Microtubule dynamics and microtubule
caps: a time-resolved cryo-electron
microscopy study . . . . . . . . . . . . 977
J. Kolega and
L. W. Janson and
D. L. Taylor The role of solation-contraction
coupling in regulating stress fiber
dynamics in nonmuscle cells . . . . . . 993
L. W. Janson and
J. Kolega and
D. L. Taylor Modulation of contraction by
gelation/solation in a reconstituted
motile model . . . . . . . . . . . . . . 1005
E. Houliston and
R. P. Elinson Evidence for the involvement of
microtubules, ER, and kinesin in the
cortical rotation of fertilized frog
eggs . . . . . . . . . . . . . . . . . . 1017
D. F. Kucik and
S. C. Kuo and
E. L. Elson and
M. P. Sheetz Preferential attachment of membrane
glycoproteins to the cytoskeleton at the
leading edge of lamella . . . . . . . . 1029
C. M. Machida and
J. D. Scott and
G. Ciment NGF-induction of the
metalloproteinase-transin/stromelysin in
PC12 cells: involvement of multiple
protein kinases . . . . . . . . . . . . 1037
K. Willecke and
R. Heynkes and
E. Dahl and
R. Stutenkemper and
H. Hennemann and
S. Jungbluth and
T. Suchyna and
B. J. Nicholson Mouse connexin37: cloning and functional
expression of a gap junction gene highly
expressed in lung . . . . . . . . . . . 1049
S. M. Albelda and
W. A. Muller and
C. A. Buck and
P. J. Newman Molecular and cellular properties of
PECAM-1 (endoCAM/CD31): a novel vascular
cell--cell adhesion molecule . . . . . . 1059
B. A. Imhof and
P. Ruiz and
B. Hesse and
R. Palacios and
D. Dunon EA-1, a novel adhesion molecule involved
in the homing of progenitor T
lymphocytes to the thymus . . . . . . . 1069
J. Solowska and
J. M. Edelman and
S. M. Albelda and
C. A. Buck Cytoplasmic and transmembrane domains of
integrin beta 1 and beta 3 subunits are
functionally interchangeable . . . . . . 1079
S. P. Massia and
J. A. Hubbell An RGD spacing of 440 nm is sufficient
for integrin alpha V beta $3$-mediated
fibroblast spreading and 140 nm for
focal contact and stress fiber formation 1089
S. Deschamps and
J. Morales and
A. Mazabraud and
M. le Maire and
H. Denis and
D. D. Brown Two forms of elongation factor 1 alpha
(EF-1 alpha O and 42Sp50), present in
oocytes, but absent in somatic cells of
\bionameXenopus laevis . . . . . . . . . 1109
J. L. Stow and
J. B. de Almeida and
N. Narula and
E. J. Holtzman and
L. Ercolani and
D. A. Ausiello A heterotrimeric G protein, G alpha i-3,
on Golgi membranes regulates the
secretion of a heparan sulfate
proteoglycan in LLC--PK1 epithelial
cells . . . . . . . . . . . . . . . . . 1113
G. Seethaler and
M. Chaminade and
R. Vlasak and
M. Ericsson and
G. Griffiths and
O. Toffoletto and
J. Rossier and
H. G. Stunnenberg and
G. Kreil Targeting of frog prodermorphin to the
regulated secretory pathway by fusion to
proenkephalin . . . . . . . . . . . . . 1125
T. Sarafian and
L. A. Pradel and
J. P. Henry and
D. Aunis and
M. F. Bader The participation of annexin II
(calpactin I) in calcium-evoked
exocytosis requires protein kinase C . . 1135
D. P. Cerneus and
A. van der Ende Apical and basolateral transferrin
receptors in polarized BeWo cells
recycle through separate endosomes . . . 1149
M. Pypaert and
D. Mundy and
E. Souter and
J. C. Labbé and
G. Warren Mitotic cytosol inhibits invagination of
coated pits in broken mitotic cells . . 1159
J. Höhfeld and
M. Veenhuis and
W. H. Kunau PAS3, a \bionameSaccharomyces cerevisiae
gene encoding a peroxisomal integral
membrane protein essential for
peroxisome biogenesis . . . . . . . . . 1167
G. P. Downey and
E. L. Elson and
B. Schwab and
S. C. Erzurum and
S. K. Young and
G. S. Worthen Biophysical properties and microfilament
assembly in neutrophils: modulation by
cyclic AMP . . . . . . . . . . . . . . . 1179
E. R. Kuczmarski and
L. Palivos and
C. Aguado and
Z. L. Yao Stopped-flow measurement of cytoskeletal
contraction: \bionameDictyostelium
myosin II is specifically required for
contraction of amoeba cytoskeletons . . 1191
C. J. Brokaw Microtubule sliding in swimming sperm
flagella: direct and indirect
measurements on sea urchin and tunicate
spermatozoa . . . . . . . . . . . . . . 1201
I. J. Yu and
D. L. Spector and
Y. S. Bae and
D. R. Marshak Immunocytochemical localization of
casein kinase II during interphase and
mitosis . . . . . . . . . . . . . . . . 1217
L. L. Peters and
C. S. Birkenmeier and
R. T. Bronson and
R. A. White and
S. E. Lux and
E. Otto and
V. Bennett and
A. Higgins and
J. E. Barker Purkinje cell degeneration associated
with erythroid ankyrin deficiency in
nb/nb mice . . . . . . . . . . . . . . . 1233
E. Kordeli and
V. Bennett Distinct ankyrin isoforms at neuron cell
bodies and nodes of Ranvier resolved
using erythrocyte ankyrin-deficient mice 1243
Y. M. Fu and
P. Spirito and
Z. X. Yu and
S. Biro and
J. Sasse and
J. Lei and
V. J. Ferrans and
S. E. Epstein and
W. Casscells Acidic fibroblast growth factor in the
developing rat embryo . . . . . . . . . 1261
G. Brunner and
J. Gabrilove and
D. B. Rifkin and
E. L. Wilson Phospholipase C release of basic
fibroblast growth factor from human bone
marrow cultures as a biologically active
complex with a
phosphatidylinositol-anchored heparan
sulfate proteoglycan . . . . . . . . . . 1275
D. M. Bradham and
A. Igarashi and
R. L. Potter and
G. R. Grotendorst Connective tissue growth factor: a
cysteine-rich mitogen secreted by human
vascular endothelial cells is related to
the SRC-induced immediate early gene
product CEF-10 . . . . . . . . . . . . . 1285
T. Nagai and
N. Yamakawa and
S. Aota and
S. S. Yamada and
S. K. Akiyama and
K. Olden and
K. M. Yamada Monoclonal antibody characterization of
two distant sites required for function
of the central cell-binding domain of
fibronectin in cell adhesion, cell
migration, and matrix assembly . . . . . 1295
L. J. Sandell and
N. Morris and
J. R. Robbins and
M. B. Goldring Alternatively spliced type II
procollagen mRNAs define distinct
populations of cells during vertebral
development: differential expression of
the amino-propeptide . . . . . . . . . . 1307
J. Pines and
T. Hunter Human cyclins A and B1 are
differentially located in the cell and
undergo cell cycle-dependent nuclear
transport . . . . . . . . . . . . . . . 1
A. M. Swift and
C. E. Machamer A Golgi retention signal in a
membrane-spanning domain of coronavirus
E1 protein . . . . . . . . . . . . . . . 19
H. Plutner and
A. D. Cox and
S. Pind and
R. Khosravi-Far and
J. R. Bourne and
R. Schwaninger and
C. J. Der and
W. E. Balch Rab1b regulates vesicular transport
between the endoplasmic reticulum and
successive Golgi compartments . . . . . 31
J. A. Fransen and
H. P. Hauri and
L. A. Ginsel and
H. Y. Naim Naturally occurring mutations in
intestinal sucrase-isomaltase provide
evidence for the existence of an
intracellular sorting signal in the
isomaltase subunit . . . . . . . . . . . 45
T. Hishikawa and
J. Y. Cheung and
R. V. Yelamarty and
D. W. Knutson Calcium transients during Fc
receptor-mediated and nonspecific
phagocytosis by murine peritoneal
macrophages . . . . . . . . . . . . . . 59
K. Kinosita and
H. Itoh and
S. Ishiwata and
K. Hirano and
T. Nishizaka and
T. Hayakawa Dual-view microscopy with a single
camera: real-time imaging of molecular
orientations and calcium . . . . . . . . 67
F. Zhang and
B. Crise and
B. Su and
Y. Hou and
J. K. Rose and
A. Bothwell and
K. Jacobson Lateral diffusion of membrane-spanning
and glycosylphosphatidylinositol-linked
proteins: toward establishing rules
governing the lateral mobility of
membrane proteins . . . . . . . . . . . 75
R. E. Mebius and
P. R. Streeter and
J. Brevé and
A. M. Duijvestijn and
G. Kraal The influence of afferent lymphatic
vessel interruption on vascular
addressin expression . . . . . . . . . . 85
M. Kruger and
J. Wright and
K. Wang Nebulin as a length regulator of thin
filaments of vertebrate skeletal
muscles: correlation of thin filament
length, nebulin size, and epitope
profile . . . . . . . . . . . . . . . . 97
D. Kulesza-Lipka and
I. C. Baines and
H. Brzeska and
E. D. Korn Immunolocalization of myosin I heavy
chain kinase in \bionameAcanthamoeba
castellanii and binding of purified
kinase to isolated plasma membranes . . 109
B. Payrastre and
P. M. van Bergen en Henegouwen and
M. Breton and
J. C. den Hartigh and
M. Plantavid and
A. J. Verkleij and
J. Boonstra Phosphoinositide kinase, diacylglycerol
kinase, and phospholipase C activities
associated to the cytoskeleton: effect
of epidermal growth factor . . . . . . . 121
M. Moudjou and
M. Paintrand and
B. Vigues and
M. Bornens A human centrosomal protein is
immunologically related to basal
body-associated proteins from lower
eucaryotes and is involved in the
nucleation of microtubules . . . . . . . 129
K. A. Stauffer and
N. M. Kumar and
N. B. Gilula and
N. Unwin Isolation and purification of gap
junction channels . . . . . . . . . . . 141
P. L. Cameron and
T. C. Südhof and
R. Jahn and
P. De Camilli Colocalization of synaptophysin with
transferrin receptors: implications for
synaptic vesicle biogenesis . . . . . . 151
D. S. Hartman and
N. S. Millar and
T. Claudio Extracellular synaptic factors induce
clustering of acetylcholine receptors
stably expressed in fibroblasts . . . . 165
D. P. Witte and
D. A. Wiginton and
J. J. Hutton and
B. J. Aronow Coordinate developmental regulation of
purine catabolic enzyme expression in
gastrointestinal and postimplantation
reproductive tracts . . . . . . . . . . 179
P. H. Quax and
G. N. van Muijen and
E. J. Weening-Verhoeff and
L. R. Lund and
K. Danò and
D. J. Ruiter and
J. H. Verheijen Metastatic behavior of human melanoma
cell lines in nude mice correlates with
urokinase-type plasminogen activator,
its type-1 inhibitor, and
urokinase-mediated matrix degradation 191
C. E. Turner Paxillin is a major
phosphotyrosine-containing protein
during embryonic development . . . . . . 201
M. Yamagata and
K. M. Yamada and
S. S. Yamada and
T. Shinomura and
H. Tanaka and
Y. Nishida and
M. Obara and
K. Kimata The complete primary structure of type
XII collagen shows a chimeric molecule
with reiterated fibronectin type III
motifs, von Willebrand factor A motifs,
a domain homologous to a noncollagenous
region of type IX collagen, and short
collagenous domains with an
Arg--Gly--Asp site . . . . . . . . . . . 209
D. E. Lorant and
K. D. Patel and
T. M. McIntyre and
R. P. McEver and
S. M. Prescott and
G. A. Zimmerman Coexpression of GMP-140 and PAF by
endothelium stimulated by histamine or
thrombin: a juxtacrine system for
adhesion and activation of neutrophils 223
S. R. Watson and
Y. Imai and
C. Fennie and
J. Geoffrey and
M. Singer and
S. D. Rosen and
L. A. Lasky The complement binding-like domains of
the murine homing receptor facilitate
lectin activity . . . . . . . . . . . . 235
P. Y. Chan and
M. B. Lawrence and
M. L. Dustin and
L. M. Ferguson and
D. E. Golan and
T. A. Springer Influence of receptor lateral mobility
on adhesion strengthening between
membranes containing LFA-3 and CD2 . . . 245
Y. Takada and
E. Murphy and
P. Pil and
C. Chen and
M. H. Ginsberg and
M. E. Hemler Molecular cloning and expression of the
cDNA for alpha 3 subunit of human alpha
3 beta 1 (VLA-3), an integrin receptor
for fibronectin, laminin, and collagen 257
S. P. Kennedy and
S. L. Warren and
B. G. Forget and
J. S. Morrow Ankyrin binds to the 15th repetitive
unit of erythroid and nonerythroid
beta-spectrin . . . . . . . . . . . . . 267
A. Chang and
C. W. Slayman Maturation of the yeast plasma membrane
[H+]ATPase involves phosphorylation
during intracellular transport . . . . . 289
C. A. Wilcox and
R. S. Fuller Posttranslational processing of the
prohormone-cleaving Kex2 protease in the
\bionameSaccharomyces cerevisiae
secretory pathway . . . . . . . . . . . 297
M. McCaffrey and
J. S. Johnson and
B. Goud and
A. M. Myers and
J. Rossier and
M. R. Popoff and
P. Madaule and
P. Boquet The small GTP-binding protein Rho1p is
localized on the Golgi apparatus and
post-Golgi vesicles in
\bionameSaccharomyces cerevisiae . . . . 309
W. F. Ettinger and
S. M. Theg Physiologically active chloroplasts
contain pools of unassembled extrinsic
proteins of the photosynthetic
oxygen-evolving enzyme complex in the
thylakoid lumen . . . . . . . . . . . . 321
P. Moran and
I. W. Caras A nonfunctional sequence converted to a
signal for glycophosphatidylinositol
membrane anchor attachment . . . . . . . 329
A. Picard and
J. C. Labbé and
H. Barakat and
J. C. Cavadore and
M. Dorée Okadaic acid mimics a nuclear component
required for cyclin B-cdc2 kinase
microinjection to drive starfish oocytes
into M phase . . . . . . . . . . . . . . 337
E. M. Tanaka and
M. W. Kirschner Microtubule behavior in the growth cones
of living neurons during axon elongation 345
S. S. Reinsch and
T. J. Mitchison and
M. Kirschner Microtubule polymer assembly and
transport during axonal elongation . . . 365
J. H. Sabry and
T. P. O'Connor and
L. Evans and
A. Toroian-Raymond and
M. Kirschner and
D. Bentley Microtubule behavior during guidance of
pioneer neuron growth cones in situ . . 381
A. Merdes and
M. Brunkener and
H. Horstmann and
S. D. Georgatos Filensin: a new vimentin-binding,
polymerization-competent, and
membrane-associated protein of the lens
fiber cell . . . . . . . . . . . . . . . 397
T. J. Byers and
L. M. Kunkel and
S. C. Watkins The subcellular distribution of
dystrophin in mouse skeletal, cardiac,
and smooth muscle . . . . . . . . . . . 411
M. J. Donoghue and
J. D. Alvarez and
J. P. Merlie and
J. R. Sanes Fiber type- and position-dependent
expression of a myosin light chain--CAT
transgene detected with a novel
histochemical stain for CAT . . . . . . 423
R. J. Bloch and
W. G. Resneck and
A. O'Neill and
J. Strong and
D. W. Pumplin Cytoplasmic components of acetylcholine
receptor clusters of cultured rat
myotubes: the 58-kD protein . . . . . . 435
K. A. Stöckli and
L. E. Lillien and
M. Näher-Noé and
G. Breitfeld and
R. A. Hughes and
M. C. Raff and
H. Thoenen and
M. Sendtner Regional distribution, developmental
changes, and cellular localization of
CNTF-mRNA and protein in the rat brain 447
A. Batistatou and
L. A. Greene Aurintricarboxylic acid rescues PC12
cells and sympathetic neurons from cell
death caused by nerve growth factor
deprivation: correlation with
suppression of endonuclease activity . . 461
B. Saad and
D. B. Constam and
R. Ortmann and
M. Moos and
A. Fontana and
M. Schachner Astrocyte-derived TGF-beta 2 and NGF
differentially regulate neural
recognition molecule expression by
cultured astrocytes . . . . . . . . . . 473
O. A. Weisz and
R. L. Schnaar Hepatocyte adhesion to
carbohydrate-derivatized surfaces. I.
Surface topography of the rat hepatic
lectin . . . . . . . . . . . . . . . . . 485
O. A. Weisz and
R. L. Schnaar Hepatocyte adhesion to
carbohydrate-derivatized surfaces. II.
Regulation of cytoskeletal organization
and cell morphology . . . . . . . . . . 495
A. Corlu and
B. Kneip and
C. Lhadi and
G. Leray and
D. Glaise and
G. Baffet and
D. Bourel and
C. Guguen-Guillouzo A plasma membrane protein is involved in
cell contact-mediated regulation of
tissue-specific genes in adult
hepatocytes . . . . . . . . . . . . . . 505
P. Navarro and
M. Gómez and
A. Pizarro and
C. Gamallo and
M. Quintanilla and
A. Cano A role for the E-cadherin cell--cell
adhesion molecule during tumor
progression of mouse epidermal
carcinogenesis . . . . . . . . . . . . . 517
C. Rochette-Egly and
Y. Lutz and
M. Saunders and
I. Scheuer and
M. P. Gaub and
P. Chambon Retinoic acid receptor gamma: specific
immunodetection and phosphorylation . . 535
F. Fuller-Pace and
G. Peters and
C. Dickson Cell transformation by kFGF requires
secretion but not glycosylation . . . . 547
Q. Zhou and
K. L. Moore and
D. F. Smith and
A. Varki and
R. P. McEver and
R. D. Cummings The selectin GMP-140 binds to
sialylated, fucosylated
lactosaminoglycans on both myeloid and
nonmyeloid cells . . . . . . . . . . . . 557
M. W. Su and
H. R. Suzuki and
J. J. Bieker and
M. Solursh and
F. Ramirez Expression of two nonallelic type II
procollagen genes during \bionameXenopus
laevis embryogenesis is characterized by
stage-specific production of
alternatively spliced transcripts . . . 565
J. R. McIntosh and
C. M. Pfarr Mitotic motors . . . . . . . . . . . . . 577
M. B. Roth and
A. M. Zahler and
J. A. Stolk A conserved family of nuclear
phosphoproteins localized to sites of
polymerase II transcription . . . . . . 587
J. Frank and
P. Penczek and
R. Grassucci and
S. Srivastava Three-dimensional reconstruction of the
70S \bionameEscherichia coli ribosome in
ice: the distribution of ribosomal RNA 597
A. Le Bivic and
Y. Sambuy and
A. Patzak and
N. Patil and
M. Chao and
E. Rodriguez-Boulan An internal deletion in the cytoplasmic
tail reverses the apical localization of
human NGF receptor in transfected MDCK
cells . . . . . . . . . . . . . . . . . 607
A. K. Bachhawat and
S. Pillai Distinct intracellular fates of membrane
and secretory immunoglobulin heavy
chains in a pre--B cell line . . . . . . 619
M. Matteoli and
K. Takei and
R. Cameron and
P. Hurlbut and
P. A. Johnston and
T. C. Südhof and
R. Jahn and
P. De Camilli Association of Rab3A with synaptic
vesicles at late stages of the secretory
pathway . . . . . . . . . . . . . . . . 625
J. Tooze and
M. Hollinshead Tubular early endosomal networks in
AtT20 and other cells . . . . . . . . . 635
R. A. Kinloch and
S. Mortillo and
C. L. Stewart and
P. M. Wassarman Embryonal carcinoma cells transfected
with ZP3 genes differentially
glycosylate similar polypeptides and
secrete active mouse sperm receptor . . 655
R. Joshi and
D. M. Gilligan and
E. Otto and
T. McLaughlin and
V. Bennett Primary structure and domain
organization of human alpha and beta
adducin . . . . . . . . . . . . . . . . 665
M. L. Cano and
D. A. Lauffenburger and
S. H. Zigmond Kinetic analysis of F-actin
depolymerization in polymorphonuclear
leukocyte lysates indicates that
chemoattractant stimulation increases
actin filament number without altering
the filament length distribution . . . . 677
A. Bremer and
R. C. Millonig and
R. Sütterlin and
A. Engel and
T. D. Pollard and
U. Aebi The structural basis for the intrinsic
disorder of the actin filament: the
``lateral slipping'' model . . . . . . . 689
K. F. Lechtreck and
M. Melkonian Striated microtubule-associated fibers:
identification of assemblin, a novel
34-kD protein that forms paracrystals of
$2$-nm filaments in vitro . . . . . . . 705
K. A. Butner and
M. W. Kirschner Tau protein binds to microtubules
through a flexible array of distributed
weak sites . . . . . . . . . . . . . . . 717
Y. Yoshihara and
S. Oka and
Y. Watanabe and
K. Mori Developmentally and spatially regulated
expression of HNK-1 carbohydrate antigen
on a novel phosphatidylinositol-anchored
glycoprotein in rat brain . . . . . . . 731
Y. Y. Zhu and
R. J. Schwartz and
M. T. Crow Phorbol esters selectively downregulate
contractile protein gene expression in
terminally differentiated myotubes
through transcriptional repression and
message destabilization . . . . . . . . 745
L. Anglister Acetylcholinesterase from the motor
nerve terminal accumulates on the
synaptic basal lamina of the myofiber 755
M. T. Lupa and
J. H. Caldwell Effect of agrin on the distribution of
acetylcholine receptors and sodium
channels on adult skeletal muscle fibers
in culture . . . . . . . . . . . . . . . 765
A. L. Calof and
A. D. Lander Relationship between neuronal migration
and cell-substratum adhesion: laminin
and merosin promote olfactory neuronal
migration but are anti-adhesive . . . . 779
M. S. Qiu and
A. F. Pitts and
T. R. Winters and
S. H. Green ras isoprenylation is required for
ras-induced but not for NGF-induced
neuronal differentiation of PC12 cells 795
N. E. Kremer and
G. D'Arcangelo and
S. M. Thomas and
M. DeMarco and
J. S. Brugge and
S. Halegoua Signal transduction by nerve growth
factor and fibroblast growth factor in
PC12 cells requires a sequence of src
and ras actions . . . . . . . . . . . . 809
M. Yaar and
K. Grossman and
M. Eller and
B. A. Gilchrest Evidence for nerve growth
factor-mediated paracrine effects in
human epidermis . . . . . . . . . . . . 821
J. C. Adams and
F. M. Watt Expression of beta 1, beta 3, beta 4,
and beta 5 integrins by human epidermal
keratinocytes and non-differentiating
keratinocytes . . . . . . . . . . . . . 829
H. M. Cooper and
R. N. Tamura and
V. Quaranta The major laminin receptor of mouse
embryonic stem cells is a novel isoform
of the alpha 6 beta 1 integrin . . . . . 843
J. Buck and
A. Myc and
A. Garbe and
G. Cathomas Differences in the action and metabolism
between retinol and retinoic acid in B
lymphocytes . . . . . . . . . . . . . . 851
O. Carpén and
M. L. Dustin and
T. A. Springer and
J. A. Swafford and
L. A. Beckett and
J. P. Caulfield Motility and ultrastructure of large
granular lymphocytes on lipid bilayers
reconstituted with adhesion receptors
LFA-1, ICAM-1, and two isoforms of LFA-3 861
C. Guidry and
M. Hook Endothelins produced by endothelial
cells promote collagen gel contraction
by fibroblasts . . . . . . . . . . . . . 873
M. Kozak An analysis of vertebrate mRNA
sequences: intimations of translational
control . . . . . . . . . . . . . . . . 887
A. Salminen and
T. Braun and
A. Buchberger and
S. Jürs and
B. Winter and
H. H. Arnold Transcription of the muscle regulatory
gene Myf4 is regulated by serum
components, peptide growth factors and
signaling pathways involving G proteins 905
W. S. Saunders and
C. A. Cooke and
W. C. Earnshaw Compartmentalization within the nucleus:
discovery of a novel subnuclear region 919
C. M. Feldherr and
D. Akin Signal-mediated nuclear transport in
proliferating and growth-arrested BALB/c
3T3 cells . . . . . . . . . . . . . . . 933
J. A. Swanson and
M. Lee and
P. E. Knapp Cellular dimensions affecting the
nucleocytoplasmic volume ratio . . . . . 941
J. M. Staddon and
M. M. Bouzyk and
E. Rozengurt A novel approach to detect
toxin-catalyzed ADP-ribosylation in
intact cells: its use to study the
action of Pasteurella multocida toxin 949
F. Lévy and
R. Larsson and
S. Kvist Translocation of peptides through
microsomal membranes is a rapid process
and promotes assembly of HLA--B27 heavy
chain and beta $2$-microglobulin
translated in vitro . . . . . . . . . . 959
K. Sandvig and
K. Prydz and
S. H. Hansen and
B. van Deurs Ricin transport in brefeldin A-treated
cells: correlation between Golgi
structure and toxic effect . . . . . . . 971
C. Valetti and
C. E. Grossi and
C. Milstein and
R. Sitia Russell bodies: a general response of
secretory cells to synthesis of a mutant
immunoglobulin which can neither exit
from, nor be degraded in, the
endoplasmic reticulum . . . . . . . . . 983
K. D. Chapman and
R. N. Trelease Acquisition of membrane lipids by
differentiating glyoxysomes: role of
lipid bodies . . . . . . . . . . . . . . 995
I. L. van Genderen and
G. van Meer and
J. W. Slot and
H. J. Geuze and
W. F. Voorhout Subcellular localization of Forssman
glycolipid in epithelial MDCK cells by
immuno-electronmicroscopy after
freeze-substitution . . . . . . . . . . 1009
P. Rafiee and
H. Leffler and
J. C. Byrd and
F. J. Cassels and
E. C. Boedeker and
Y. S. Kim A sialoglycoprotein complex linked to
the microvillus cytoskeleton acts as a
receptor for pilus (AF/R1) mediated
adhesion of enteropathogenic
\bionameEscherichia coli (RDEC-1) in
rabbit small intestine . . . . . . . . . 1021
M. Terasaki and
C. Sardet Demonstration of calcium uptake and
release by sea urchin egg cortical
endoplasmic reticulum . . . . . . . . . 1031
N. Funayama and
A. Nagafuchi and
N. Sato and
S. Tsukita and
S. Tsukita Radixin is a novel member of the band
4.1 family . . . . . . . . . . . . . . . 1039
T. Kanaseki and
Y. Ikeuchi and
H. Sugiura and
T. Yamauchi Structural features of
Ca$^{2+}$/calmodulin-dependent protein
kinase II revealed by electron
microscopy . . . . . . . . . . . . . . . 1049
J. E. Vance and
D. Pan and
D. E. Vance and
R. B. Campenot Biosynthesis of membrane lipids in rat
axons . . . . . . . . . . . . . . . . . 1061
J. E. Yeadon and
H. Lin and
S. M. Dyer and
S. J. Burden Dystrophin is a component of the
subsynaptic membrane . . . . . . . . . . 1069
D. L. Paul and
L. Ebihara and
L. J. Takemoto and
K. I. Swenson and
D. A. Goodenough Connexin46, a novel lens gap junction
protein, induces voltage-gated currents
in nonjunctional plasma membrane of
\bionameXenopus oocytes . . . . . . . . 1077
R. W. Pelton and
B. Saxena and
M. Jones and
H. L. Moses and
L. I. Gold Immunohistochemical localization of TGF
beta 1, TGF beta 2, and TGF beta 3 in
the mouse embryo: expression patterns
suggest multiple roles during embryonic
development . . . . . . . . . . . . . . 1091
L. Ossowski and
G. Clunie and
M. T. Masucci and
F. Blasi In vivo paracrine interaction between
urokinase and its receptor: effect on
tumor cell invasion . . . . . . . . . . 1107
T. B. Kuhn and
E. T. Stoeckli and
M. A. Condrau and
F. G. Rathjen and
P. Sonderegger Neurite outgrowth on immobilized
axonin-1 is mediated by a heterophilic
interaction with L1(G4) . . . . . . . . 1113
J. E. Murphy-Ullrich and
V. A. Lightner and
I. Aukhil and
Y. Z. Yan and
H. P. Erickson and
M. Höök Focal adhesion integrity is
downregulated by the alternatively
spliced domain of human tenascin . . . . 1127
A. P. Skubitz and
P. C. Letourneau and
E. Wayner and
L. T. Furcht Synthetic peptides from the
carboxy-terminal globular domain of the
A chain of laminin: their ability to
promote cell adhesion and neurite
outgrowth, and interact with heparin and
the beta 1 integrin subunit . . . . . . 1137
H. Neuhaus and
M. C. Hu and
M. E. Hemler and
Y. Takada and
B. Holzmann and
I. L. Weissman Cloning and expression of cDNAs for the
alpha subunit of the murine
lymphocyte--Peyer's patch adhesion
molecule . . . . . . . . . . . . . . . . 1149
E. M. Kurz and
T. W. Holstein and
B. M. Petri and
J. Engel and
C. N. David Mini-collagens in hydra nematocytes . . 1159
D. K. Bonen and
T. M. Schmid Elevated extracellular calcium
concentrations induce type X collagen
synthesis in chondrocyte cultures . . . 1171
P. T. Lakkakorpi and
M. A. Horton and
M. H. Helfrich and
E. K. Karhukorpi and
H. K. Väänänen Vitronectin receptor has a role in bone
resorption but does not mediate tight
sealing zone attachment of osteoclasts
to the bone surface . . . . . . . . . . 1179
K. C. Carter and
K. L. Taneja and
J. B. Lawrence Discrete nuclear domains of poly(A) RNA
and their relationship to the functional
organization of the nucleus . . . . . . 1191
D. A. Jans and
M. J. Ackermann and
J. R. Bischoff and
D. H. Beach and
R. Peters p34cdc2-mediated phosphorylation at T124
inhibits nuclear import of SV-40 T
antigen proteins . . . . . . . . . . . . 1203
J. Pieters and
H. Horstmann and
O. Bakke and
G. Griffiths and
J. Lipp Intracellular transport and localization
of major histocompatibility complex
class II molecules and associated
invariant chain . . . . . . . . . . . . 1213
F. J. Stafford and
J. S. Bonifacino A permeabilized cell system identifies
the endoplasmic reticulum as a site of
protein degradation . . . . . . . . . . 1225
R. M. Hemmer and
S. G. Donkin and
K. J. Chin and
D. G. Grenache and
H. Bhatt and
S. M. Politz Altered expression of an L1-specific,
O-linked cuticle surface glycoprotein in
mutants of the nematode
\bionameCaenorhabditis elegans . . . . . 1237
L. C. Stewart and
M. P. Yaffe A role for unsaturated fatty acids in
mitochondrial movement and inheritance 1249
R. A. Fluck and
A. L. Miller and
L. F. Jaffe Slow calcium waves accompany cytokinesis
in medaka fish eggs . . . . . . . . . . 1259
S. Eliott and
P. H. Vardy and
K. L. Williams The distribution of myosin II in
\bionameDictyostelium discoideum slug
cells . . . . . . . . . . . . . . . . . 1267
T. Usui and
M. Yoshida and
K. Abe and
H. Osada and
K. Isono and
T. Beppu Uncoupled cell cycle without mitosis
induced by a protein kinase inhibitor,
K-252a . . . . . . . . . . . . . . . . . 1275
R. L. Camp and
T. A. Kraus and
E. Puré Variations in the cytoskeletal
interaction and posttranslational
modification of the CD44 homing receptor
in macrophages . . . . . . . . . . . . . 1283
B. L. Bader and
T. M. Magin and
M. Freudenmann and
S. Stumpp and
W. W. Franke Intermediate filaments formed de novo
from tail-less cytokeratins in the
cytoplasm and in the nucleus . . . . . . 1293
T. A. Schroer and
M. P. Sheetz Two activators of microtubule-based
vesicle transport . . . . . . . . . . . 1309
M. Kunimoto and
E. Otto and
V. Bennett A new 440-kD isoform is the major
ankyrin in neonatal rat brain . . . . . 1319
P. W. Baas and
T. P. Pienkowski and
K. S. Kosik Processes induced by tau expression in
Sf9 cells have an axon-like microtubule
organization . . . . . . . . . . . . . . 1333
B. E. Flucher and
J. L. Phillips and
J. A. Powell Dihydropyridine receptor alpha subunits
in normal and dysgenic muscle in vitro:
expression of alpha 1 is required for
proper targeting and distribution of
alpha 2 . . . . . . . . . . . . . . . . 1345
L. S. Musil and
D. A. Goodenough Biochemical analysis of connexin43
intracellular transport,
phosphorylation, and assembly into gap
junctional plaques . . . . . . . . . . . 1357
M. E. el-Sabban and
B. U. Pauli Cytoplasmic dye transfer between
metastatic tumor cells and vascular
endothelium . . . . . . . . . . . . . . 1375
C. H. Streuli and
N. Bailey and
M. J. Bissell Control of mammary epithelial
differentiation: basement membrane
induces tissue-specific gene expression
in the absence of cell--cell interaction
and morphological polarity . . . . . . . 1383
D. Cassio and
C. Hamon-Benais and
M. Guérin and
O. Lecoq Hybrid cell lines constitute a potential
reservoir of polarized cells: isolation
and study of highly differentiated
hepatoma-derived hybrid cells able to
form functional bile canaliculi in vitro 1397
T. Lesuffleur and
A. Barbat and
C. Luccioni and
J. Beaumatin and
M. Clair and
A. Kornowski and
E. Dussaulx and
B. Dutrillaux and
A. Zweibaum Dihydrofolate reductase gene
amplification-associated shift of
differentiation in methotrexate-adapted
HT-29 cells . . . . . . . . . . . . . . 1409
T. M. Guadagno and
R. K. Assoian G1\slash S control of
anchorage-independent growth in the
fibroblast cell cycle . . . . . . . . . 1419
C. E. Klein and
D. Dressel and
T. Steinmayer and
C. Mauch and
B. Eckes and
T. Krieg and
R. B. Bankert and
L. Weber Integrin alpha 2 beta 1 is upregulated
in fibroblasts and highly aggressive
melanoma cells in three-dimensional
collagen lattices and mediates the
reorganization of collagen I fibrils . . 1427
D. N. Cooper and
S. M. Massa and
S. H. Barondes Endogenous muscle lectin inhibits
myoblast adhesion to laminin . . . . . . 1437
M. Itoh and
S. Yonemura and
A. Nagafuchi and
S. Tsukita and
S. Tsukita A 220-kD undercoat-constitutive protein:
its specific localization at
cadherin-based cell--cell adhesion sites 1449
R. C. Spiro and
H. H. Freeze and
D. Sampath and
J. A. Garcia Uncoupling of chondroitin sulfate
glycosaminoglycan synthesis by brefeldin
A . . . . . . . . . . . . . . . . . . . 1463
T. Hirano and
T. J. Mitchison Cell cycle control of higher-order
chromatin assembly around naked DNA in
vitro . . . . . . . . . . . . . . . . . 1479
S. A. Tooze and
T. Flatmark and
J. Tooze and
W. B. Huttner Characterization of the immature
secretory granule, an intermediate in
granule biogenesis . . . . . . . . . . . 1491
E. Chanat and
W. B. Huttner Milieu-induced, selective aggregation of
regulated secretory proteins in the
trans-Golgi network . . . . . . . . . . 1505
K. W. Moremen and
P. W. Robbins Isolation, characterization, and
expression of cDNAs encoding murine
alpha-mannosidase II, a Golgi enzyme
that controls conversion of high mannose
to complex N-glycans . . . . . . . . . . 1521
J. M. Backer and
S. E. Shoelson and
E. Haring and
M. F. White Insulin receptors internalize by a
rapid, saturable pathway requiring
receptor autophosphorylation and an
intact juxtamembrane region . . . . . . 1535
I. Tabas and
J. N. Myers and
T. L. Innerarity and
X. X. Xu and
K. Arnold and
J. Boyles and
F. R. Maxfield The influence of particle size and
multiple apoprotein E-receptor
interactions on the endocytic targeting
of beta--VLDL in mouse peritoneal
macrophages . . . . . . . . . . . . . . 1547
T. Ludwig and
G. Griffiths and
B. Hoflack Distribution of newly synthesized
lysosomal enzymes in the endocytic
pathway of normal rat kidney cells . . . 1561
I. R. Nabi and
A. Le Bivic and
D. Fambrough and
E. Rodriguez-Boulan An endogenous MDCK lysosomal membrane
glycoprotein is targeted basolaterally
before delivery to lysosomes . . . . . . 1573
E. Fire and
D. E. Zwart and
M. G. Roth and
Y. I. Henis Evidence from lateral mobility studies
for dynamic interactions of a mutant
influenza hemagglutinin with coated pits 1585
P. Moran and
I. W. Caras Fusion of sequence elements from
non-anchored proteins to generate a
fully functional signal for
glycophosphatidylinositol membrane
anchor attachment . . . . . . . . . . . 1595
U. Wienhues and
K. Becker and
M. Schleyer and
B. Guiard and
M. Tropschug and
A. L. Horwich and
N. Pfanner and
W. Neupert Protein folding causes an arrest of
preprotein translocation into
mitochondria in vivo . . . . . . . . . . 1601
S. K. Maciver and
H. G. Zot and
T. D. Pollard Characterization of actin filament
severing by actophorin from
\bionameAcanthamoeba castellanii . . . . 1611
S. K. Maciver and
D. H. Wachsstock and
W. H. Schwarz and
T. D. Pollard The actin filament severing protein
actophorin promotes the formation of
rigid bundles of actin filaments
crosslinked with alpha-actinin . . . . . 1621
E. L. Bearer Direct observation of actin filament
severing by gelsolin and binding by
gCap39 and CapZ . . . . . . . . . . . . 1629
S. R. Gill and
T. A. Schroer and
I. Szilak and
E. R. Steuer and
M. P. Sheetz and
D. W. Cleveland Dynactin, a conserved, ubiquitously
expressed component of an activator of
vesicle motility mediated by cytoplasmic
dynein . . . . . . . . . . . . . . . . . 1639
J. L. Cheshire and
L. R. Keller Uncoupling of \bionameChlamydomonas
flagellar gene expression and outgrowth
from flagellar excision by manipulation
of Ca$^{2+}$ . . . . . . . . . . . . . . 1651
P. A. Coulombe and
M. E. Hutton and
R. Vassar and
E. Fuchs A function for keratins and a common
thread among different types of
epidermolysis bullosa simplex diseases 1661
H. Baribault and
R. G. Oshima Polarized and functional epithelia can
form after the targeted inactivation of
both mouse keratin 8 alleles . . . . . . 1675
K. Ohlendieck and
K. P. Campbell Dystrophin-associated proteins are
greatly reduced in skeletal muscle from
mdx mice . . . . . . . . . . . . . . . . 1685
T. M. Nguyen and
J. M. Ellis and
D. R. Love and
K. E. Davies and
K. C. Gatter and
G. Dickson and
G. E. Morris Localization of the DMDL gene-encoded
dystrophin-related protein using a panel
of nineteen monoclonal antibodies:
presence at neuromuscular junctions, in
the sarcolemma of dystrophic skeletal
muscle, in vascular and other smooth
muscles, and in proliferating brain cell
lines . . . . . . . . . . . . . . . . . 1695
P. R. Turner and
P. Y. Fong and
W. F. Denetclaw and
R. A. Steinhardt Increased calcium influx in dystrophic
muscle . . . . . . . . . . . . . . . . . 1701
W. D. Phillips and
M. M. Maimone and
J. P. Merlie Mutagenesis of the 43-kD postsynaptic
protein defines domains involved in
plasma membrane targeting and AChR
clustering . . . . . . . . . . . . . . . 1713
L. L. Rubin and
D. E. Hall and
S. Porter and
K. Barbu and
C. Cannon and
H. C. Horner and
M. Janatpour and
C. W. Liaw and
K. Manning and
J. Morales A cell culture model of the blood-brain
barrier . . . . . . . . . . . . . . . . 1725
M. A. Kurpakus and
V. Quaranta and
J. C. Jones Surface relocation of alpha 6 beta 4
integrins and assembly of hemidesmosomes
in an in vitro model of wound healing 1737
J. Aoki and
M. Umeda and
K. Takio and
K. Titani and
H. Utsumi and
M. Sasaki and
K. Inoue Neural cell adhesion molecule mediates
contact-dependent inhibition of growth
of near-diploid mouse fibroblast cell
line m5S/1M . . . . . . . . . . . . . . 1751
P. Kristensen and
J. Eriksen and
F. Blasi and
K. Danò Two alternatively spliced mouse
urokinase receptor mRNAs with different
histological localization in the
gastrointestinal tract . . . . . . . . . 1763
H. J. Ehrlich and
R. K. Gebbink and
K. T. Preissner and
J. Keijer and
N. L. Esmon and
K. Mertens and
H. Pannekoek Thrombin neutralizes plasminogen
activator inhibitor 1 (PAI-1) that is
complexed with vitronectin in the
endothelial cell matrix . . . . . . . . 1773
S. Klaus and
A. M. Cassard-Doulcier and
D. Ricquier Development of Phodopus sungorus brown
preadipocytes in primary cell culture:
effect of an atypical beta-adrenergic
agonist, insulin, and triiodothyronine
on differentiation, mitochondrial
development, and expression of the
uncoupling protein UCP . . . . . . . . . 1783
B. A. Peculis and
J. G. Gall Localization of the nucleolar protein
NO38 in amphibian oocytes . . . . . . . 1
U. F. Greber and
L. Gerace Nuclear protein import is inhibited by
an antibody to a lumenal epitope of a
nuclear pore complex glycoprotein . . . 15
S. J. Busch and
G. A. Martin and
R. L. Barnhart and
M. Mano and
A. D. Cardin and
R. L. Jackson Trans-repressor activity of nuclear
glycosaminoglycans on Fos and Jun/AP-1
oncoprotein-mediated transcription . . . 31
W. Krek and
G. Maridor and
E. A. Nigg Casein kinase II is a predominantly
nuclear enzyme . . . . . . . . . . . . . 43
Y. S. Tsao and
N. E. Ivessa and
M. Adesnik and
D. D. Sabatini and
G. Kreibich Carboxy terminally truncated forms of
ribophorin I are degraded in pre-Golgi
compartments by a calcium-dependent
process . . . . . . . . . . . . . . . . 57
J. Alcalde and
P. Bonay and
A. Roa and
S. Vilaro and
I. V. Sandoval Assembly and disassembly of the Golgi
complex: two processes arranged in a
cis-trans direction . . . . . . . . . . 69
B. Reaves and
G. Banting Perturbation of the morphology of the
trans-Golgi network following Brefeldin
A treatment: redistribution of a
TGN-specific integral membrane protein,
TGN38 . . . . . . . . . . . . . . . . . 85
S. Rabinowitz and
H. Horstmann and
S. Gordon and
G. Griffiths Immunocytochemical characterization of
the endocytic and phagolysosomal
compartments in peritoneal macrophages 95
S. Arber and
K. H. Krause and
P. Caroni s-cyclophilin is retained
intracellularly via a unique
COOH-terminal sequence and colocalizes
with the calcium storage protein
calreticulin . . . . . . . . . . . . . . 113
D. Perrin and
K. Möller and
K. Hanke and
H. D. Söling cAMP and Ca(2+)-mediated secretion in
parotid acinar cells is associated with
reversible changes in the organization
of the cytoskeleton . . . . . . . . . . 127
D. I. Mundy and
G. Warren Mitosis and inhibition of intracellular
transport stimulate palmitoylation of a
62-kD protein . . . . . . . . . . . . . 135
J. K. Han and
K. Fukami and
R. Nuccitelli Reducing inositol lipid hydrolysis,
Ins(1,4,5)P3 receptor availability, or
Ca$^{2+}$ gradients lengthens the
duration of the cell cycle in
\bionameXenopus laevis blastomeres . . . 147
M. Hatzfeld and
K. Weber A synthetic peptide representing the
consensus sequence motif at the
carboxy-terminal end of the rod domain
inhibits intermediate filament assembly
and disassembles preformed filaments . . 157
D. Wren and
G. Wolswijk and
M. Noble In vitro analysis of the origin and
maintenance of O-2Aadult progenitor
cells . . . . . . . . . . . . . . . . . 167
D. Muir and
M. Manthorpe Stromelysin generates a fibronectin
fragment that inhibits Schwann cell
proliferation . . . . . . . . . . . . . 177
S. P. Wu and
D. Theodorescu and
R. S. Kerbel and
J. K. Willson and
K. M. Mulder and
L. E. Humphrey and
M. G. Brattain TGF-beta 1 is an autocrine-negative
growth regulator of human colon
carcinoma FET cells in vivo as revealed
by transfection of an antisense
expression vector . . . . . . . . . . . 187
V. B. Young and
S. Falkow and
G. K. Schoolnik The invasin protein of Yersinia
enterocolitica: internalization of
invasin-bearing bacteria by eukaryotic
cells is associated with reorganization
of the cytoskeleton . . . . . . . . . . 197
G. P. Tuszynski and
V. L. Rothman and
A. H. Deutch and
B. K. Hamilton and
J. Eyal Biological activities of peptides and
peptide analogues derived from common
sequences present in thrombospondin,
properdin, and malarial proteins . . . . 209
I. Dransfield and
C. Cabañas and
A. Craig and
N. Hogg Divalent cation regulation of the
function of the leukocyte integrin LFA-1 219
D. Pavlin and
A. C. Lichtler and
A. Bedalov and
B. E. Kream and
J. R. Harrison and
H. F. Thomas and
G. A. Gronowicz and
S. H. Clark and
C. O. Woody and
D. W. Rowe Differential utilization of regulatory
domains within the alpha 1(I) collagen
promoter in osseous and fibroblastic
cells . . . . . . . . . . . . . . . . . 227
M. J. Matunis and
E. L. Matunis and
G. Dreyfuss Isolation of hnRNP complexes from
\bionameDrosophila melanogaster . . . . 245
E. L. Matunis and
M. J. Matunis and
G. Dreyfuss Characterization of the major hnRNP
proteins from \bionameDrosophila
melanogaster . . . . . . . . . . . . . . 257
R. Sterne-Marr and
J. M. Blevitt and
L. Gerace O-linked glycoproteins of the nuclear
pore complex interact with a cytosolic
factor required for nuclear protein
import . . . . . . . . . . . . . . . . . 271
A. L. Boman and
M. R. Delannoy and
K. L. Wilson GTP hydrolysis is required for vesicle
fusion during nuclear envelope assembly
in vitro . . . . . . . . . . . . . . . . 281
J. Newport and
W. Dunphy Characterization of the membrane binding
and fusion events during nuclear
envelope assembly using purified
components . . . . . . . . . . . . . . . 295
N. D. Ridgway and
P. A. Dawson and
Y. K. Ho and
M. S. Brown and
J. L. Goldstein Translocation of oxysterol binding
protein to Golgi apparatus triggered by
ligand binding . . . . . . . . . . . . . 307
I. Wada and
W. H. Lai and
B. I. Posner and
J. J. Bergeron Association of the tyrosine
phosphorylated epidermal growth factor
receptor with a 55-kD tyrosine
phosphorylated protein at the cell
surface and in endosomes . . . . . . . . 321
P. G. Woodman and
D. I. Mundy and
P. Cohen and
G. Warren Cell-free fusion of endocytic vesicles
is regulated by phosphorylation . . . . 331
J. M. Wahlberg and
H. Garoff Membrane fusion process of Semliki
Forest virus. I: Low pH-induced
rearrangement in spike protein
quaternary structure precedes virus
penetration into cells . . . . . . . . . 339
A. Salminen and
J. M. Wahlberg and
M. Lobigs and
P. Liljeström and
H. Garoff Membrane fusion process of Semliki
Forest virus. II: Cleavage-dependent
reorganization of the spike protein
complex controls virus entry . . . . . . 349
D. Scheuner and
C. D. Logsdon and
R. W. Holz Bovine chromaffin granule membranes
undergo Ca(2+)-regulated exocytosis in
frog oocytes . . . . . . . . . . . . . . 359
H. G. Zot and
S. K. Doberstein and
T. D. Pollard Myosin-I moves actin filaments on a
phospholipid substrate: implications for
membrane targeting . . . . . . . . . . . 367
A. Pereira and
J. Doshen and
E. Tanaka and
L. S. Goldstein Genetic analysis of a \bionameDrosophila
microtubule-associated protein . . . . . 377
R. A. Chavez and
Z. W. Hall Expression of fusion proteins of the
nicotinic acetylcholine receptor from
mammalian muscle identifies the
membrane-spanning regions in the alpha
and delta subunits . . . . . . . . . . . 385
G. J. Kidd and
J. W. Heath and
B. D. Trapp and
P. R. Dunkley Myelin sheath survival after
guanethidine-induced axonal degeneration 395
B. M. Wice and
J. I. Gordon A strategy for isolation of cDNAs
encoding proteins affecting human
intestinal epithelial cell growth and
differentiation: characterization of a
novel gut-specific N-myristoylated
annexin . . . . . . . . . . . . . . . . 405
B. J. Bast and
L. J. Zhou and
G. J. Freeman and
K. J. Colley and
T. J. Ernst and
J. M. Munro and
T. F. Tedder The HB-6, CDw75, and CD76
differentiation antigens are unique
cell-surface carbohydrate determinants
generated by the beta-galactoside alpha
2,6-sialyltransferase . . . . . . . . . 423
V. Gattei and
P. A. Bernabei and
A. Pinto and
R. Bezzini and
A. Ringressi and
L. Formigli and
A. Tanini and
V. Attadia and
M. L. Brandi Phorbol ester induced osteoclast-like
differentiation of a novel human
leukemic cell line (FLG 29.1) . . . . . 437
R. J. Bloch Clusters of neural cell adhesion
molecule at sites of cell--cell contact 449
S. Asakura and
R. W. Hurley and
K. Skorstengaard and
I. Ohkubo and
D. F. Mosher Inhibition of cell adhesion by high
molecular weight kininogen . . . . . . . 465
J. S. Bauer and
C. L. Schreiner and
F. G. Giancotti and
E. Ruoslahti and
R. L. Juliano Motility of fibronectin
receptor-deficient cells on fibronectin
and vitronectin: collaborative
interactions among integrins . . . . . . 477
E. A. Wayner and
N. L. Kovach Activation-dependent recognition by
hematopoietic cells of the LDV sequence
in the V region of fibronectin . . . . . 489
N. L. Kovach and
T. M. Carlos and
E. Yee and
J. M. Harlan A monoclonal antibody to beta 1 integrin
(CD29) stimulates VLA-dependent
adherence of leukocytes to human
umbilical vein endothelial cells and
matrix components . . . . . . . . . . . 499
D. M. Mosser and
T. A. Springer and
M. S. Diamond Leishmania promastigotes require opsonic
complement to bind to the human
leukocyte integrin Mac-1 (CD11b/CD18) 511
A. E. Faassen and
J. A. Schrager and
D. J. Klein and
T. R. Oegema and
J. R. Couchman and
J. B. McCarthy A cell surface chondroitin sulfate
proteoglycan, immunologically related to
CD44, is involved in type I
collagen-mediated melanoma cell motility
and invasion . . . . . . . . . . . . . . 521
E. W. Raines and
R. Ross Compartmentalization of PDGF on
extracellular binding sites dependent on
exon-$6$-encoded sequences . . . . . . . 533
T. H. Lee and
H. G. Wisniewski and
J. Vilcek A novel secretory tumor necrosis
factor-inducible protein (TSG-6) is a
member of the family of hyaluronate
binding proteins, closely related to the
adhesion receptor CD44 . . . . . . . . . 545
P. Kallunki and
K. Tryggvason Human basement membrane heparan sulfate
proteoglycan core protein: a 467-kD
protein containing multiple domains
resembling elements of the low density
lipoprotein receptor, laminin, neural
cell adhesion molecules, and epidermal
growth factor . . . . . . . . . . . . . 559
K. Mostov and
G. Apodaca and
B. Aroeti and
C. Okamoto Plasma membrane protein sorting in
polarized epithelial cells . . . . . . . 577
Y. Muro and
H. Masumoto and
K. Yoda and
N. Nozaki and
M. Ohashi and
T. Okazaki Centromere protein B assembles human
centromeric alpha-satellite DNA at the $
17$-bp sequence, CENP--B box . . . . . . 585
N. Green and
H. Fang and
P. Walter Mutants in three novel complementation
groups inhibit membrane protein
insertion into and soluble protein
translocation across the endoplasmic
reticulum membrane of
\bionameSaccharomyces cerevisiae . . . . 597
D. S. Yaver and
S. Matoba and
D. M. Ogrydziak A mutation in the signal recognition
particle 7S RNA of the yeast Yarrowia
lipolytica preferentially affects
synthesis of the alkaline extracellular
protease: in vivo evidence for
translational arrest . . . . . . . . . . 605
J. A. Koedam and
E. M. Cramer and
E. Briend and
B. Furie and
B. C. Furie and
D. D. Wagner P-selectin, a granule membrane protein
of platelets and endothelial cells,
follows the regulated secretory pathway
in AtT-20 cells . . . . . . . . . . . . 617
S. Tartare and
R. Ballotti and
R. Lammers and
C. Filloux and
A. Chauvel and
J. Schlessinger and
A. Ullrich and
E. Van Obberghen Activation of insulin-epidermal growth
factor (EGF) receptor chimerae regulates
EGF receptor binding affinity . . . . . 627
C. Oliver and
N. Sahara and
S. Kitani and
A. R. Robbins and
L. M. Mertz and
R. P. Siraganian Binding of monoclonal antibody AA4 to
gangliosides on rat basophilic leukemia
cells produces changes similar to those
seen with Fc epsilon receptor activation 635
K. R. Foltz and
W. J. Lennarz Identification of the sea urchin egg
receptor for sperm using an antiserum
raised against a fragment of its
extracellular domain . . . . . . . . . . 647
K. Arikawa and
L. L. Molday and
R. S. Molday and
D. S. Williams Localization of peripherin/rds in the
disk membranes of cone and rod
photoreceptors: relationship to disk
membrane morphogenesis and retinal
degeneration . . . . . . . . . . . . . . 659
K. D. Becker and
P. T. O'Donnell and
J. M. Heitz and
M. Vito and
S. I. Bernstein Analysis of \bionameDrosophila
paramyosin: identification of a novel
isoform which is restricted to a subset
of adult muscles . . . . . . . . . . . . 669
J. A. Porter and
J. L. Hicks and
D. S. Williams and
C. Montell Differential localizations of and
requirements for the two
\bionameDrosophila ninaC kinase/myosins
in photoreceptor cells . . . . . . . . . 683
G. P. Downey and
C. K. Chan and
P. Lea and
A. Takai and
S. Grinstein Phorbol ester-induced actin assembly in
neutrophils: role of protein kinase C 695
T. Hunt and
F. C. Luca and
J. V. Ruderman The requirements for protein synthesis
and degradation, and the control of
destruction of cyclins A and B in the
meiotic and mitotic cell cycles of the
clam embryo . . . . . . . . . . . . . . 707
R. S. Freeman and
A. N. Meyer and
J. Li and
D. J. Donoghue Phosphorylation of conserved serine
residues does not regulate the ability
of mosxe protein kinase to induce oocyte
maturation or function as cytostatic
factor . . . . . . . . . . . . . . . . . 725
L. M. Quarmby and
Y. G. Yueh and
J. L. Cheshire and
L. R. Keller and
W. J. Snell and
R. C. Crain Inositol phospholipid metabolism may
trigger flagellar excision in
\bionameChlamydomonas reinhardtii . . . 737
J. R. Monck and
A. F. Oberhauser and
T. J. Keating and
J. M. Fernandez Thin-section ratiometric Ca$^{2+}$
images obtained by optical sectioning of
fura-2 loaded mast cells . . . . . . . . 745
M. K. Bennett and
N. Calakos and
T. Kreiner and
R. H. Scheller Synaptic vesicle membrane proteins
interact to form a multimeric complex 761
H. Kimura and
D. Schubert Schwannoma-derived growth factor
promotes the neuronal differentiation
and survival of PC12 cells . . . . . . . 777
A. W. Hudson and
M. Ruiz and
M. J. Birnbaum Isoform-specific subcellular targeting
of glucose transporters in mouse
fibroblasts . . . . . . . . . . . . . . 785
M. E. Lowe Site-specific mutations in the
COOH-terminus of placental alkaline
phosphatase: a single amino acid change
converts a
phosphatidylinositol-glycan-anchored
protein to a secreted protein . . . . . 799
K. M. Neugebauer and
K. A. Venstrom and
L. F. Reichardt Adhesion of a chicken myeloblast cell
line to fibrinogen and vitronectin
through a beta $1$-class integrin . . . 809
S. Jalkanen and
M. Jalkanen Lymphocyte CD44 binds the COOH-terminal
heparin-binding domain of fibronectin 817
D. T. Hung and
T. H. Vu and
N. A. Nelken and
S. R. Coughlin Thrombin-induced events in non-platelet
cells are mediated by the unique
proteolytic mechanism established for
the cloned platelet thrombin receptor 827
B. Kastner and
U. Kornstädt and
M. Bach and
R. Lührmann Structure of the small nuclear RNP
particle U1: identification of the two
structural protuberances with
RNP-antigens A and 70K . . . . . . . . . 839
N. Michaud and
D. Goldfarb Microinjected U snRNAs are imported to
oocyte nuclei via the nuclear pore
complex by three distinguishable
targeting pathways . . . . . . . . . . . 851
G. James and
E. Olson Deletion of the regulatory domain of
protein kinase C alpha exposes regions
in the hinge and catalytic domains that
mediate nuclear targeting . . . . . . . 863
H. M. Miettinen and
K. Matter and
W. Hunziker and
J. K. Rose and
I. Mellman Fc receptor endocytosis is controlled by
a cytoplasmic domain determinant that
actively prevents coated pit
localization . . . . . . . . . . . . . . 875
D. A. Wollner and
K. A. Krzeminski and
W. J. Nelson Remodeling the cell surface distribution
of membrane proteins during the
development of epithelial cell polarity 889
P. A. Orlandi and
F. W. Klotz and
J. D. Haynes A malaria invasion receptor, the $
175$-kilodalton erythrocyte binding
antigen of \bionamePlasmodium falciparum
recognizes the terminal Neu5Ac(alpha
2-3)Gal- sequences of glycophorin A . . 901
E. M. Roulier and
C. Fyrberg and
E. Fyrberg Perturbations of \bionameDrosophila
alpha-actinin cause muscle paralysis,
weakness, and atrophy but do not confer
obvious nonmuscle phenotypes . . . . . . 911
C. Hug and
T. M. Miller and
M. A. Torres and
J. F. Casella and
J. A. Cooper Identification and characterization of
an actin-binding site of CapZ . . . . . 923
H. Ohmori and
S. Toyama and
S. Toyama Direct proof that the primary site of
action of cytochalasin on cell motility
processes is actin . . . . . . . . . . . 933
D. Cox and
J. Condeelis and
D. Wessels and
D. Soll and
H. Kern and
D. A. Knecht Targeted disruption of the ABP-120 gene
leads to cells with altered motility . . 943
M. de Cuevas and
T. Tao and
L. S. Goldstein Evidence that the stalk of
\bionameDrosophila kinesin heavy chain
is an alpha-helical coiled coil . . . . 957
G. Maldonado-Codina and
D. M. Glover Cyclins A and B associate with chromatin
and the polar regions of spindles,
respectively, and do not undergo
complete degradation at anaphase in
syncytial \bionameDrosophila embryos . . 967
J. A. Nickerson and
G. Krockmalnic and
K. M. Wan and
C. D. Turner and
S. Penman A normally masked nuclear matrix antigen
that appears at mitosis on cytoskeleton
filaments adjoining chromosomes,
centrioles, and midbodies . . . . . . . 977
M. Ozawa and
R. Kemler Molecular organization of the
uvomorulin-catenin complex . . . . . . . 989
A. Tözeren and
K. L. Sung and
L. A. Sung and
M. L. Dustin and
P. Y. Chan and
T. A. Springer and
S. Chien Micromanipulation of adhesion of a
Jurkat cell to a planar bilayer membrane
containing lymphocyte
function-associated antigen 3 molecules 997
G. Berton and
C. Laudanna and
C. Sorio and
F. Rossi Generation of signals activating
neutrophil functions by leukocyte
integrins: LFA-1 and gp150/95, but not
CR3, are able to stimulate the
respiratory burst of human neutrophils 1007
J. W. Schmidt and
J. S. Brugge and
W. J. Nelson pp60src tyrosine kinase modulates P19
embryonal carcinoma cell fate by
inhibiting neuronal but not epithelial
differentiation . . . . . . . . . . . . 1019
K. Böhme and
M. Conscience-Egli and
T. Tschan and
K. H. Winterhalter and
P. Bruckner Induction of proliferation or
hypertrophy of chondrocytes in
serum-free culture: the role of
insulin-like growth factor--I, insulin,
or thyroxine . . . . . . . . . . . . . . 1035
J. C. Dunn and
R. G. Tompkins and
M. L. Yarmush Hepatocytes in collagen sandwich:
evidence for transcriptional and
translational regulation . . . . . . . . 1043
M. Culty and
H. A. Nguyen and
C. B. Underhill The hyaluronan receptor (CD44)
participates in the uptake and
degradation of hyaluronan . . . . . . . 1055
R. Probstmeier and
T. Fahrig and
E. Spiess and
M. Schachner Interactions of the neural cell adhesion
molecule and the myelin-associated
glycoprotein with collagen type I:
involvement in fibrillogenesis . . . . . 1063
R. D. Klausner and
J. G. Donaldson and
J. Lippincott-Schwartz Brefeldin A: insights into the control
of membrane traffic and organelle
structure . . . . . . . . . . . . . . . 1071
A. F. Pluta and
N. Saitoh and
I. Goldberg and
W. C. Earnshaw Identification of a subdomain of CENP--B
that is necessary and sufficient for
localization to the human centromere . . 1081
R. T. O'Keefe and
S. C. Henderson and
D. L. Spector Dynamic organization of DNA replication
in mammalian cell nuclei: spatially and
temporally defined replication of
chromosome-specific alpha-satellite DNA
sequences . . . . . . . . . . . . . . . 1095
S. M. McPherson and
P. S. McPherson and
L. Mathews and
K. P. Campbell and
F. J. Longo Cortical localization of a calcium
release channel in sea urchin eggs . . . 1111
M. L. Cano and
L. Cassimeris and
M. Fechheimer and
S. H. Zigmond Mechanisms responsible for F-actin
stabilization after lysis of
polymorphonuclear leukocytes . . . . . . 1123
M. Way and
B. Pope and
A. G. Weeds Are the conserved sequences in segment 1
of gelsolin important for binding actin? 1135
J. Finidori and
E. Friederich and
D. J. Kwiatkowski and
D. Louvard In vivo analysis of functional domains
from villin and gelsolin . . . . . . . . 1145
U. Euteneuer and
M. Schliwa Mechanism of centrosome positioning
during the wound response in BSC-1 cells 1157
W. E. Theurkauf and
R. S. Hawley Meiotic spindle assembly in
\bionameDrosophila females: behavior of
nonexchange chromosomes and the effects
of mutations in the nod kinesin-like
protein . . . . . . . . . . . . . . . . 1167
A. Letai and
P. A. Coulombe and
E. Fuchs Do the ends justify the mean? Proline
mutations at the ends of the keratin
coiled-coil rod segment are more
disruptive than internal mutations . . . 1181
T. S. Stappenbeck and
K. J. Green The desmoplakin carboxyl terminus
coaligns with and specifically disrupts
intermediate filament networks when
expressed in cultured cells . . . . . . 1197
R. Pardi and
L. Inverardi and
C. Rugarli and
J. R. Bender Antigen-receptor complex stimulation
triggers protein kinase C-dependent
CD11a/CD18-cytoskeleton association in T
lymphocytes . . . . . . . . . . . . . . 1211
D. E. Levin and
E. Bartlett-Heubusch Mutants in the S. cerevisiae PKC1 gene
display a cell cycle-specific osmotic
stability defect . . . . . . . . . . . . 1221
P. W. Baas and
F. J. Ahmad The plus ends of stable microtubules are
the exclusive nucleating structures for
microtubules in the axon . . . . . . . . 1231
M. G. Cusella-De Angelis and
G. Lyons and
C. Sonnino and
L. De Angelis and
E. Vivarelli and
K. Farmer and
W. E. Wright and
M. Molinaro and
M. Bouch\`e and
M. Buckingham MyoD, myogenin independent
differentiation of primordial myoblasts
in mouse somites . . . . . . . . . . . . 1243
P. Boukamp and
J. Chen and
F. Gonzales and
P. A. Jones and
N. E. Fusenig Progressive stages of
``transdifferentiation'' from epidermal
to mesenchymal phenotype induced by
MyoD1 transfection,
$5$-aza-2'-deoxycytidine treatment, and
selection for reduced cell attachment in
the human keratinocyte line HaCaT . . . 1257
M. T. Shieh and
D. WuDunn and
R. I. Montgomery and
J. D. Esko and
P. G. Spear Cell surface receptors for herpes
simplex virus are heparan sulfate
proteoglycans . . . . . . . . . . . . . 1273
D. L. Adelson and
M. C. Alliegro and
D. R. McClay On the ultrastructure of hyalin, a cell
adhesion protein of the sea urchin
embryo extracellular matrix . . . . . . 1283
C. M. West and
G. W. Erdos Incorporation of protein into spore
coats is not cell autonomous in
\bionameDictyostelium . . . . . . . . . 1291
C. H. Yang and
E. J. Lambie and
M. Snyder NuMA: an unusually long coiled-coil
related protein in the mammalian nucleus 1303
C. Mirzayan and
C. S. Copeland and
M. Snyder The NUF1 gene encodes an essential
coiled-coil related protein that is a
potential component of the yeast
nucleoskeleton . . . . . . . . . . . . . 1319
D. Choubey and
P. Lengyel Interferon action: nucleolar and
nucleoplasmic localization of the
interferon-inducible 72-kD protein that
is encoded by the Ifi 204 gene from the
gene 200 cluster . . . . . . . . . . . . 1333
H. W. Davidson and
C. H. McGowan and
W. E. Balch Evidence for the regulation of exocytic
transport by protein phosphorylation . . 1343
A. Tan and
J. Bolscher and
C. Feltkamp and
H. Ploegh Retrograde transport from the Golgi
region to the endoplasmic reticulum is
sensitive to GTP gamma S . . . . . . . . 1357
L. Hemmings and
P. A. Kuhlman and
D. R. Critchley Analysis of the actin-binding domain of
alpha-actinin by mutagenesis and
demonstration that dystrophin contains a
functionally homologous domain . . . . . 1369
A. W. Crawford and
J. W. Michelsen and
M. C. Beckerle An interaction between zyxin and
alpha-actinin . . . . . . . . . . . . . 1381
D. A. Compton and
I. Szilak and
D. W. Cleveland Primary structure of NuMA, an
intranuclear protein that defines a
novel pathway for segregation of
proteins at mitosis . . . . . . . . . . 1395
E. Shelden and
P. Wadsworth Microinjection of biotin-tubulin into
anaphase cells induces transient
elongation of kinetochore microtubules
and reversal of chromosome-to-pole
motion . . . . . . . . . . . . . . . . . 1409
A. Fernandez and
D. L. Brautigan and
N. J. Lamb Protein phosphatase type 1 in mammalian
cell mitosis: chromosomal localization
and involvement in mitotic exit . . . . 1421
B. Buendia and
G. Draetta and
E. Karsenti Regulation of the microtubule nucleating
activity of centrosomes in
\bionameXenopus egg extracts: role of
cyclin A-associated protein kinase . . . 1431
S. Kamimura and
R. Kamiya High-frequency vibration in flagellar
axonemes with amplitudes reflecting the
size of tubulin . . . . . . . . . . . . 1443
R. Curtis and
H. J. Stewart and
S. M. Hall and
G. P. Wilkin and
R. Mirsky and
K. R. Jessen GAP-43 is expressed by nonmyelin-forming
Schwann cells of the peripheral nervous
system . . . . . . . . . . . . . . . . . 1455
D. D. Ginty and
G. R. Fanger and
J. A. Wagner and
R. A. Maue The activity of cAMP-dependent protein
kinase is required at a
posttranslational level for induction of
voltage-dependent sodium channels by
peptide growth factors in PC12 cells . . 1465
K. Husmann and
A. Faissner and
M. Schachner Tenascin promotes cerebellar granule
cell migration and neurite outgrowth by
different domains in the fibronectin
type III repeats . . . . . . . . . . . . 1475
P. Yang and
X. Yin and
U. Rutishauser Intercellular space is affected by the
polysialic acid content of NCAM . . . . 1487
Y. Hieda and
Y. Nishizawa and
J. Uematsu and
K. Owaribe Identification of a new hemidesmosomal
protein, HD1: a major, high molecular
mass component of isolated
hemidesmosomes . . . . . . . . . . . . . 1497
S. C. Stamatoglou and
C. Enrich and
M. M. Manson and
R. C. Hughes Temporal changes in the expression and
distribution of adhesion molecules
during liver development and
regeneration . . . . . . . . . . . . . . 1507
A. R. Moser and
W. F. Dove and
K. A. Roth and
J. I. Gordon The Min (multiple intestinal neoplasia)
mutation: its effect on gut epithelial
cell differentiation and interaction
with a modifier system . . . . . . . . . 1517
I. Dransfield and
C. Cabañas and
J. Barrett and
N. Hogg Interaction of leukocyte integrins with
ligand is necessary but not sufficient
for function . . . . . . . . . . . . . . 1527
M. Carmo-Fonseca and
R. Pepperkok and
M. T. Carvalho and
A. I. Lamond Transcription-dependent colocalization
of the U1, U2, U4/U6, and U5 snRNPs in
coiled bodies . . . . . . . . . . . . . 1
G. Migliaccio and
C. V. Nicchitta and
G. Blobel The signal sequence receptor, unlike the
signal recognition particle receptor, is
not essential for protein translocation 15
N. Narula and
I. McMorrow and
G. Plopper and
J. Doherty and
K. S. Matlin and
B. Burke and
J. L. Stow Identification of a 200-kD,
brefeldin-sensitive protein on Golgi
membranes . . . . . . . . . . . . . . . 27
M. Yokode and
R. K. Pathak and
R. E. Hammer and
M. S. Brown and
J. L. Goldstein and
R. G. Anderson Cytoplasmic sequence required for
basolateral targeting of LDL receptor in
livers of transgenic mice . . . . . . . 39
S. A. Green and
R. B. Kelly Low density lipoprotein receptor and
cation-independent mannose $6$-phosphate
receptor are transported from the cell
surface to the Golgi apparatus at equal
rates in PC12 cells . . . . . . . . . . 47
P. J. Sammak and
S. R. Adams and
A. T. Harootunian and
M. Schliwa and
R. Y. Tsien Intracellular cyclic AMP not calcium,
determines the direction of vesicle
movement in melanophores: direct
measurement by fluorescence ratio
imaging . . . . . . . . . . . . . . . . 57
M. S. Kolodney and
R. B. Wysolmerski Isometric contraction by fibroblasts and
endothelial cells in tissue culture: a
quantitative study . . . . . . . . . . . 73
D. S. Adams Mechanisms of cell shape change: the
cytomechanics of cellular response to
chemical environment and mechanical
loading . . . . . . . . . . . . . . . . 83
A. Hemphill and
M. Affolter and
T. Seebeck A novel microtubule-binding motif
identified in a high molecular weight
microtubule-associated protein from
Trypanosoma brucei . . . . . . . . . . . 95
S. Okabe and
N. Hirokawa Differential behavior of photoactivated
microtubules in growing axons of mouse
and frog neurons . . . . . . . . . . . . 105
W. C. Wetsel and
W. A. Khan and
I. Merchenthaler and
H. Rivera and
A. E. Halpern and
H. M. Phung and
A. Negro-Vilar and
Y. A. Hannun Tissue and cellular distribution of the
extended family of protein kinase C
isoenzymes . . . . . . . . . . . . . . . 121
Y. Ma and
R. B. Campenot and
F. D. Miller Concentration-dependent regulation of
neuronal gene expression by nerve growth
factor . . . . . . . . . . . . . . . . . 135
J. Z. Levin and
H. R. Horvitz The \bionameCaenorhabditis elegans
unc-93 gene encodes a putative
transmembrane protein that regulates
muscle contraction . . . . . . . . . . . 143
K. Sandberg and
H. Ji and
T. Iida and
K. J. Catt Intercellular communication between
follicular angiotensin receptors and
\bionameXenopus laevis oocytes:
medication by an inositol
1,4,5-trisphosphate-dependent mechanism 157
S. Citi Protein kinase inhibitors prevent
junction dissociation induced by low
extracellular calcium in MDCK epithelial
cells . . . . . . . . . . . . . . . . . 169
C. Rüegg and
A. A. Postigo and
E. E. Sikorski and
E. C. Butcher and
R. Pytela and
D. J. Erle Role of integrin alpha 4 beta 7/alpha 4
beta P in lymphocyte adherence to
fibronectin and VCAM-1 and in homotypic
cell clustering . . . . . . . . . . . . 179
D. J. Carey and
D. M. Evans and
R. C. Stahl and
V. K. Asundi and
K. J. Conner and
P. Garbes and
G. Cizmeci-Smith Molecular cloning and characterization
of N-syndecan, a novel transmembrane
heparan sulfate proteoglycan . . . . . . 191
S. Felder and
J. LaVin and
A. Ullrich and
J. Schlessinger Kinetics of binding, endocytosis, and
recycling of EGF receptor mutants . . . 203
P. Gallant and
E. A. Nigg Cyclin B2 undergoes cell cycle-dependent
nuclear translocation and, when
expressed as a non-destructible mutant,
causes mitotic arrest in HeLa cells . . 213
G. J. Snipes and
U. Suter and
A. A. Welcher and
E. M. Shooter Characterization of a novel peripheral
nervous system myelin protein
(PMP-22/SR13) . . . . . . . . . . . . . 225
S. H. Wong and
S. H. Low and
W. Hong The $ 17$-residue transmembrane domain
of beta-galactoside alpha
2,6-sialyltransferase is sufficient for
Golgi retention . . . . . . . . . . . . 245
D. Jeckel and
A. Karrenbauer and
K. N. Burger and
G. van Meer and
F. Wieland Glucosylceramide is synthesized at the
cytosolic surface of various Golgi
subfractions . . . . . . . . . . . . . . 259
M. D. Turner and
M. E. Rennison and
S. E. Handel and
C. J. Wilde and
R. D. Burgoyne Proteins are secreted by both
constitutive and regulated secretory
pathways in lactating mouse mammary
epithelial cells . . . . . . . . . . . . 269
A. Pelchen-Matthews and
I. Boulet and
D. R. Littman and
R. Fagard and
M. Marsh The protein tyrosine kinase p56lck
inhibits CD4 endocytosis by preventing
entry of CD4 into coated pits . . . . . 279
D. D. Eveleth and
R. A. Bradshaw Nerve growth factor nonresponsive
pheochromocytoma cells: altered
internalization results in signaling
dysfunction . . . . . . . . . . . . . . 291
K. W. Dunn and
F. R. Maxfield Delivery of ligands from sorting
endosomes to late endosomes occurs by
maturation of sorting endosomes . . . . 301
C. Harter and
I. Mellman Transport of the lysosomal membrane
glycoprotein lgp120 (lgp--A) to
lysosomes does not require appearance on
the plasma membrane . . . . . . . . . . 311
J. T. Tzen and
A. H. Huang Surface structure and properties of
plant seed oil bodies . . . . . . . . . 327
J. S. Frank and
G. Mottino and
D. Reid and
R. S. Molday and
K. D. Philipson Distribution of the Na(+)-Ca$^{2+}$
exchange protein in mammalian cardiac
myocytes: an immunofluorescence and
immunocolloidal gold-labeling study . . 337
R. G. Fenton and
H. F. Kung and
D. L. Longo and
M. R. Smith Regulation of intracellular actin
polymerization by prenylated cellular
proteins . . . . . . . . . . . . . . . . 347
D. M. Baorto and
W. Mellado and
M. L. Shelanski Astrocyte process growth induction by
actin breakdown . . . . . . . . . . . . 357
H. J. Hathaway and
B. D. Shur Cell surface beta
1,4-galactosyltransferase functions
during neural crest cell migration and
neurulation in vivo . . . . . . . . . . 369
P. P. Roger and
M. Baptist and
J. E. Dumont A mechanism generating heterogeneity in
thyroid epithelial cells: suppression of
the thyrotropin/cAMP-dependent mitogenic
pathway after cell division induced by
cAMP-independent factors . . . . . . . . 383
D. Lindholm and
E. Castrén and
R. Kiefer and
F. Zafra and
H. Thoenen Transforming growth factor-beta 1 in the
rat brain: increase after injury and
inhibition of astrocyte proliferation 395
T. A. Woodford-Thomas and
J. D. Rhodes and
J. E. Dixon Expression of a protein tyrosine
phosphatase in normal and
v-src-transformed mouse 3T3 fibroblasts 401
M. J. Wheelock and
P. J. Jensen Regulation of keratinocyte intercellular
junction organization and epidermal
morphogenesis by E-cadherin . . . . . . 415
F. Descalzi Cancedda and
C. Gentili and
P. Manduca and
R. Cancedda Hypertrophic chondrocytes undergo
further differentiation in culture . . . 427
S. E. LaFlamme and
S. K. Akiyama and
K. M. Yamada Regulation of fibronectin receptor
distribution . . . . . . . . . . . . . . 437
K. R. Gehlsen and
P. Sriramarao and
L. T. Furcht and
A. P. Skubitz A synthetic peptide derived from the
carboxy terminus of the laminin A chain
represents a binding site for the alpha
3 beta 1 integrin . . . . . . . . . . . 449
E. van de Wiel-van Kemenade and
Y. van Kooyk and
A. J. de Boer and
R. J. Huijbens and
P. Weder and
W. van de Kasteele and
C. J. Melief and
C. G. Figdor Adhesion of T and B lymphocytes to
extracellular matrix and endothelial
cells can be regulated through the beta
subunit of VLA . . . . . . . . . . . . . 461
U. Stochaj and
P. A. Silver A conserved phosphoprotein that
specifically binds nuclear localization
sequences is involved in nuclear import 473
A. L. Olins and
D. E. Olins and
D. P. Bazett-Jones Balbiani ring hnRNP substructure
visualized by selective staining and
electron spectroscopic imaging . . . . . 483
P. J. Rapiejko and
R. Gilmore Protein translocation across the ER
requires a functional GTP binding site
in the alpha subunit of the signal
recognition particle receptor . . . . . 493
T. Marquardt and
A. Helenius Misfolding and aggregation of newly
synthesized proteins in the endoplasmic
reticulum . . . . . . . . . . . . . . . 505
R. J. Duronio and
L. J. Knoll and
J. I. Gordon Isolation of a \bionameSaccharomyces
cerevisiae long chain fatty acyl: CoA
synthetase gene (FAA1) and assessment of
its role in protein N-myristoylation . . 515
D. W. Wilson and
S. W. Whiteheart and
M. Wiedmann and
M. Brunner and
J. E. Rothman A multisubunit particle implicated in
membrane fusion . . . . . . . . . . . . 531
M. Grimes and
R. B. Kelly Intermediates in the constitutive and
regulated secretory pathways released in
vitro from semi-intact cells . . . . . . 539
C. Zurzolo and
C. Polistina and
M. Saini and
R. Gentile and
L. Aloj and
G. Migliaccio and
S. Bonatti and
L. Nitsch Opposite polarity of virus budding and
of viral envelope glycoprotein
distribution in epithelial cells derived
from different tissues . . . . . . . . . 551
T. W. Kuijpers and
B. C. Hakkert and
M. H. Hart and
D. Roos Neutrophil migration across monolayers
of cytokine-prestimulated endothelial
cells: a role for platelet-activating
factor and IL-8 . . . . . . . . . . . . 565
E. F. Smith and
W. S. Sale Structural and functional reconstitution
of inner dynein arms in
\bionameChlamydomonas flagellar axonemes 573
M. B. Omary and
G. T. Baxter and
C. F. Chou and
C. L. Riopel and
W. Y. Lin and
B. Strulovici PKC epsilon-related kinase associates
with and phosphorylates cytokeratin 8
and 18 . . . . . . . . . . . . . . . . . 583
A. Ferreira and
J. Niclas and
R. D. Vale and
G. Banker and
K. S. Kosik Suppression of kinesin expression in
cultured hippocampal neurons using
antisense oligonucleotides . . . . . . . 595
R. J. Lasek and
P. Paggi and
M. J. Katz Slow axonal transport mechanisms move
neurofilaments relentlessly in mouse
optic axons . . . . . . . . . . . . . . 607
C. L. Rosen and
M. P. Lisanti and
J. L. Salzer Expression of unique sets of GPI-linked
proteins by different primary neurons in
vitro . . . . . . . . . . . . . . . . . 617
M. Parvinen and
M. Pelto-Huikko and
O. Söder and
R. Schultz and
A. Kaipia and
P. Mali and
J. Toppari and
H. Hakovirta and
P. Lönnerberg and
E. M. Ritzén Expression of beta-nerve growth factor
and its receptor in rat seminiferous
epithelium: specific function at the
onset of meiosis . . . . . . . . . . . . 629
W. K. Song and
W. Wang and
R. F. Foster and
D. A. Bielser and
S. J. Kaufman H36-alpha 7 is a novel integrin alpha
chain that is developmentally regulated
during skeletal myogenesis . . . . . . . 643
A. G. Arroyo and
P. Sánchez-Mateos and
M. R. Campanero and
I. Martín-Padura and
E. Dejana and
F. Sánchez-Madrid Regulation of the VLA integrin-ligand
interactions through the beta 1 subunit 659
E. C. Lee and
M. M. Lotz and
G. D. Steele and
A. M. Mercurio The integrin alpha 6 beta 4 is a laminin
receptor . . . . . . . . . . . . . . . . 671
A. König and
L. Bruckner-Tuderman Transforming growth factor-beta
stimulates collagen VII expression by
cutaneous cells in vitro . . . . . . . . 679
Q. Chen and
C. Linsenmayer and
H. Gu and
T. M. Schmid and
T. F. Linsenmayer Domains of type X collagen: alteration
of cartilage matrix by fibril
association and proteoglycan
accumulation . . . . . . . . . . . . . . 687
C. Y. Kao and
R. K. Draper Retention of secretory proteins in an
intermediate compartment and
disappearance of the Golgi complex in an
END4 mutant of Chinese hamster ovary
cells . . . . . . . . . . . . . . . . . 701
S. L. Milgram and
R. C. Johnson and
R. E. Mains Expression of individual forms of
peptidylglycine alpha-amidating
monooxygenase in AtT-20 cells:
endoproteolytic processing and routing
to secretory granules . . . . . . . . . 717
R. C. Piper and
C. Tai and
J. W. Slot and
C. S. Hahn and
C. M. Rice and
H. Huang and
D. E. James The efficient intracellular
sequestration of the insulin-regulatable
glucose transporter (GLUT-4) is
conferred by the NH2 terminus . . . . . 729
L. Ghitescu and
M. Bendayan Transendothelial transport of serum
albumin: a quantitative
immunocytochemical study . . . . . . . . 745
C. A. Parkos and
S. P. Colgan and
C. Delp and
M. A. Arnaout and
J. L. Madara Neutrophil migration across a cultured
epithelial monolayer elicits a biphasic
resistance response representing
sequential effects on transcellular and
paracellular pathways . . . . . . . . . 757
T. D. Coates and
R. G. Watts and
R. Hartman and
T. H. Howard Relationship of F-actin distribution to
development of polar shape in human
polymorphonuclear neutrophils . . . . . 765
G. Schevzov and
C. Lloyd and
P. Gunning High level expression of transfected
beta- and gamma-actin genes
differentially impacts on myoblast
cytoarchitecture . . . . . . . . . . . . 775
C. Lloyd and
G. Schevzov and
P. Gunning Transfection of nonmuscle beta- and
gamma-actin genes into myoblasts elicits
different feedback regulatory responses
from endogenous actin genes . . . . . . 787
R. M. Tombes and
C. Simerly and
G. G. Borisy and
G. Schatten Meiosis, egg activation, and nuclear
envelope breakdown are differentially
reliant on Ca$^{2+}$, whereas germinal
vesicle breakdown is Ca$^{2+}$
independent in the mouse oocyte . . . . 799
I. U. Wacker and
J. E. Rickard and
J. R. De Mey and
T. E. Kreis Accumulation of a microtubule-binding
protein, pp170, at desmosomal plaques 813
S. M. Hauft and
S. H. Kim and
G. H. Schmidt and
S. Pease and
S. Rees and
S. Harris and
K. A. Roth and
J. R. Hansbrough and
S. M. Cohn and
D. J. Ahnen Expression of SV-40 T antigen in the
small intestinal epithelium of
transgenic mice results in proliferative
changes in the crypt and reentry of
villus-associated enterocytes into the
cell cycle but has no apparent effect on
cellular differentiation programs and
does not cause neoplastic transformation 825
J. R. Forsayeth and
Y. Gu and
Z. W. Hall BiP forms stable complexes with
unassembled subunits of the
acetylcholine receptor in transfected
COS cells and in C2 muscle cells . . . . 841
M. Matteoli and
K. Takei and
M. S. Perin and
T. C. Südhof and
P. De Camilli Exo-endocytotic recycling of synaptic
vesicles in developing processes of
cultured hippocampal neurons . . . . . . 849
K. A. Paschke and
F. Lottspeich and
C. A. Stuermer Neurolin, a cell surface glycoprotein on
growing retinal axons in the goldfish
visual system, is reexpressed during
retinal axonal regeneration . . . . . . 863
P. Durbec and
G. Gennarini and
C. Goridis and
G. Rougon A soluble form of the F3 neuronal cell
adhesion molecule promotes neurite
outgrowth . . . . . . . . . . . . . . . 877
Y. Uehara and
N. Kitamura Expression of a human hepatocyte growth
factor/scatter factor cDNA in MDCK
epithelial cells influences cell
morphology, motility, and
anchorage-independent growth . . . . . . 889
C. Foxall and
S. R. Watson and
D. Dowbenko and
C. Fennie and
L. A. Lasky and
M. Kiso and
A. Hasegawa and
D. Asa and
B. K. Brandley The three members of the selectin
receptor family recognize a common
carbohydrate epitope, the sialyl
Lewis(x) oligosaccharide . . . . . . . . 895
A. Nakai and
M. Satoh and
K. Hirayoshi and
K. Nagata Involvement of the stress protein HSP47
in procollagen processing in the
endoplasmic reticulum . . . . . . . . . 903
C. E. Shamu and
A. W. Murray Sister chromatid separation in frog egg
extracts requires DNA topoisomerase II
activity during anaphase . . . . . . . . 921
F. Klein and
T. Laroche and
M. E. Cardenas and
J. F. Hofmann and
D. Schweizer and
S. M. Gasser Localization of RAP1 and topoisomerase
II in nuclei and meiotic chromosomes of
yeast . . . . . . . . . . . . . . . . . 935
N. E. Ivessa and
C. De Lemos-Chiarandini and
Y. S. Tsao and
A. Takatsuki and
M. Adesnik and
D. D. Sabatini and
G. Kreibich O-glycosylation of intact and truncated
ribophorins in brefeldin A-treated
cells: newly synthesized intact
ribophorins are only transiently
accessible to the relocated
glycosyltransferases . . . . . . . . . . 949
J. Roitelman and
E. H. Olender and
S. Bar-Nun and
W. A. Dunn and
R. D. Simoni Immunological evidence for eight spans
in the membrane domain of
$3$-hydroxy-$3$-methylglutaryl coenzyme
A reductase: implications for enzyme
degradation in the endoplasmic reticulum 959
G. Pietrini and
D. Aggujaro and
P. Carrera and
J. Malyszko and
A. Vitale and
N. Borgese A single mRNA, transcribed from an
alternative, erythroid-specific,
promoter, codes for two non-myristylated
forms of NADH-cytochrome b5 reductase 975
K. Metsikkö and
T. Hentunen and
K. Väänänen Local expression and exocytosis of viral
glycoproteins in multinucleated muscle
cells . . . . . . . . . . . . . . . . . 987
G. A. Porter and
G. M. Dmytrenko and
J. C. Winkelmann and
R. J. Bloch Dystrophin colocalizes with
beta-spectrin in distinct subsarcolemmal
domains in mammalian skeletal muscle . . 997
M. H. Lu and
C. DiLullo and
T. Schultheiss and
S. Holtzer and
J. M. Murray and
J. Choi and
D. A. Fischman and
H. Holtzer The
vinculin/sarcomeric-alpha-actinin/alpha-actin nexus in cultured cardiac myocytes 1007
L. G. Cao and
G. G. Babcock and
P. A. Rubenstein and
Y. L. Wang Effects of profilin and profilactin on
actin structure and function in living
cells . . . . . . . . . . . . . . . . . 1023
D. Chrétien and
F. Metoz and
F. Verde and
E. Karsenti and
R. H. Wade Lattice defects in microtubules:
protofilament numbers vary within
individual microtubules . . . . . . . . 1031
J. R. Hamaguchi and
R. A. Tobey and
J. Pines and
H. A. Crissman and
T. Hunter and
E. M. Bradbury Requirement for p34cdc2 kinase is
restricted to mitosis in the mammalian
cdc2 mutant FT210 . . . . . . . . . . . 1041
H. Masuda and
M. Sevik and
W. Z. Cande In vitro microtubule-nucleating activity
of spindle pole bodies in fission yeast
\bionameSchizosaccharomyces pombe: cell
cycle-dependent activation in
\bionameXenopus cell-free extracts . . . 1055
J. F. Amatruda and
J. A. Cooper Purification, characterization, and
immunofluorescence localization of
\bionameSaccharomyces cerevisiae capping
protein . . . . . . . . . . . . . . . . 1067
A. D. Linstedt and
M. L. Vetter and
J. M. Bishop and
R. B. Kelly Specific association of the
proto-oncogene product pp60c-src with an
intracellular organelle, the PC12
synaptic vesicle . . . . . . . . . . . . 1077
C. M. Troy and
L. A. Greene and
M. L. Shelanski Neurite outgrowth in peripherin-depleted
PC12 cells . . . . . . . . . . . . . . . 1085
P. Doherty and
S. V. Ashton and
S. D. Skaper and
A. Leon and
F. S. Walsh Ganglioside modulation of neural cell
adhesion molecule and
N-cadherin-dependent neurite outgrowth 1093
D. I. Leavesley and
G. D. Ferguson and
E. A. Wayner and
D. A. Cheresh Requirement of the integrin beta 3
subunit for carcinoma cell spreading or
migration on vitronectin and fibrinogen 1101
J. J. Grzesiak and
G. E. Davis and
D. Kirchhofer and
M. D. Pierschbacher Regulation of alpha 2 beta $1$-mediated
fibroblast migration on type I collagen
by shifts in the concentrations of
extracellular Mg2+ and Ca$^{2+}$ . . . . 1109
P. D. Yurchenco and
Y. S. Cheng and
H. Colognato Laminin forms an independent network in
basement membranes . . . . . . . . . . . 1119
R. P. Beckmann and
M. Lovett and
W. J. Welch Examining the function and regulation of
hsp 70 in cells subjected to metabolic
stress . . . . . . . . . . . . . . . . . 1137
R. Baler and
W. J. Welch and
R. Voellmy Heat shock gene regulation by nascent
polypeptides and denatured proteins:
hsp70 as a potential autoregulatory
factor . . . . . . . . . . . . . . . . . 1151
J. L. Dixon and
R. Chattapadhyay and
T. Huima and
C. M. Redman and
D. Banerjee Biosynthesis of lipoprotein: location of
nascent apoAI and apoB in the rough
endoplasmic reticulum of chicken
hepatocytes . . . . . . . . . . . . . . 1161
D. H. Wong and
F. M. Brodsky $ 100$-kD proteins of Golgi- and
trans-Golgi network-associated coated
vesicles have related but distinct
membrane binding properties . . . . . . 1171
L. J. Robinson and
S. Pang and
D. S. Harris and
J. Heuser and
D. E. James Translocation of the glucose transporter
(GLUT4) to the cell surface in
permeabilized 3T3-L1 adipocytes: effects
of ATP insulin, and GTP gamma S and
localization of GLUT4 to clathrin
lattices . . . . . . . . . . . . . . . . 1181
W. I. Lencer and
C. Delp and
M. R. Neutra and
J. L. Madara Mechanism of cholera toxin action on a
polarized human intestinal epithelial
cell line: role of vesicular traffic . . 1197
S. K. Mallya and
J. S. Partin and
M. C. Valdizan and
W. J. Lennarz Proteolysis of the major yolk
glycoproteins is regulated by
acidification of the yolk platelets in
sea urchin embryos . . . . . . . . . . . 1211
D. Applegate and
J. D. Pardee Actin-facilitated assembly of smooth
muscle myosin induces formation of
actomyosin fibrils . . . . . . . . . . . 1223
S. Yumura and
T. Kitanishi-Yumura Release of myosin II from the
membrane-cytoskeleton of
\bionameDictyostelium discoideum
mediated by heavy-chain phosphorylation
at the foci within the cortical actin
network . . . . . . . . . . . . . . . . 1231
S. K. Doberstein and
T. D. Pollard Localization and specificity of the
phospholipid and actin binding sites on
the tail of \bionameAcanthamoeba myosin
IC . . . . . . . . . . . . . . . . . . . 1241
C. Brancolini and
S. Bottega and
C. Schneider Gas2, a growth arrest-specific protein,
is a component of the microfilament
network system . . . . . . . . . . . . . 1251
F. Navone and
J. Niclas and
N. Hom-Booher and
L. Sparks and
H. D. Bernstein and
G. McCaffrey and
R. D. Vale Cloning and expression of a human
kinesin heavy chain gene: interaction of
the COOH-terminal domain with
cytoplasmic microtubules in transfected
CV-1 cells . . . . . . . . . . . . . . . 1263
E. A. Vallen and
M. A. Hiller and
T. Y. Scherson and
M. D. Rose Separate domains of KAR1 mediate
distinct functions in mitosis and
nuclear fusion . . . . . . . . . . . . . 1277
W. L. Dentler and
C. Adams Flagellar microtubule dynamics in
\bionameChlamydomonas: cytochalasin D
induces periods of microtubule
shortening and elongation; and
colchicine induces disassembly of the
distal, but not proximal, half of the
flagellum . . . . . . . . . . . . . . . 1289
H. Hennemann and
T. Suchyna and
H. Lichtenberg-Fraté and
S. Jungbluth and
E. Dahl and
J. Schwarz and
B. J. Nicholson and
K. Willecke Molecular cloning and functional
expression of mouse connexin40, a second
gap junction gene preferentially
expressed in lung . . . . . . . . . . . 1299
B. A. Murray and
J. J. Jensen Evidence for heterophilic adhesion of
embryonic retinal cells and
neuroblastoma cells to
substratum-adsorbed NCAM . . . . . . . . 1311
A. A. Reszka and
Y. Hayashi and
A. F. Horwitz Identification of amino acid sequences
in the integrin beta 1 cytoplasmic
domain implicated in cytoskeletal
association . . . . . . . . . . . . . . 1321
S. L. Drake and
D. J. Klein and
D. J. Mickelson and
T. R. Oegema and
L. T. Furcht and
J. B. McCarthy Cell surface
phosphatidylinositol-anchored heparan
sulfate proteoglycan initiates mouse
melanoma cell adhesion to a
fibronectin-derived, heparin-binding
synthetic peptide . . . . . . . . . . . 1331
C. Hardwick and
K. Hoare and
R. Owens and
H. P. Hohn and
M. Hook and
D. Moore and
V. Cripps and
L. Austen and
D. M. Nance and
E. A. Turley Molecular cloning of a novel hyaluronan
receptor that mediates tumor cell
motility . . . . . . . . . . . . . . . . 1343
S. J. Pancake and
G. D. Holt and
S. Mellouk and
S. L. Hoffman Malaria sporozoites and circumsporozoite
proteins bind specifically to sulfated
glycoconjugates . . . . . . . . . . . . 1351
C. Dargemont and
L. C. Kühn Export of mRNA from microinjected nuclei
of \bionameXenopus laevis oocytes . . . 1
C. Kambach and
I. W. Mattaj Intracellular distribution of the U1A
protein depends on active transport and
nuclear binding to U1 snRNA . . . . . . 11
C. Goday and
J. M. González-García and
M. R. Esteban and
G. Giovinazzo and
S. Pimpinelli Kinetochores and chromatin diminution in
early embryos of Parascaris univalens 23
A. Fujishige and
K. R. Smith and
J. L. Silen and
D. A. Agard Correct folding of alpha-lytic protease
is required for its extracellular
secretion from \bionameEscherichia coli 33
L. V. Lotti and
M. R. Torrisi and
M. C. Pascale and
S. Bonatti Immunocytochemical analysis of the
transfer of vesicular stomatitis virus G
glycoprotein from the intermediate
compartment to the Golgi complex . . . . 43
S. H. Low and
B. L. Tang and
S. H. Wong and
W. Hong Selective inhibition of protein
targeting to the apical domain of MDCK
cells by brefeldin A . . . . . . . . . . 51
W. J. Chang and
K. G. Rothberg and
B. A. Kamen and
R. G. Anderson Lowering the cholesterol content of
MA104 cells inhibits receptor-mediated
transport of folate . . . . . . . . . . 63
L. G. Tilney and
D. J. DeRosier and
M. S. Tilney How \bionameListeria exploits host cell
actin to form its own cytoskeleton. I.
Formation of a tail and how that tail
might be involved in movement . . . . . 71
L. G. Tilney and
D. J. DeRosier and
A. Weber and
M. S. Tilney How \bionameListeria exploits host cell
actin to form its own cytoskeleton. II.
Nucleation, actin filament polarity,
filament assembly, and evidence for a
pointed end capper . . . . . . . . . . . 83
D. M. Roof and
P. B. Meluh and
M. D. Rose Kinesin-related proteins required for
assembly of the mitotic spindle . . . . 95
M. A. Hoyt and
L. He and
K. K. Loo and
W. S. Saunders Two \bionameSaccharomyces cerevisiae
kinesin-related gene products required
for mitotic spindle assembly . . . . . . 109
K. L. Vikstrom and
S. S. Lim and
R. D. Goldman and
G. G. Borisy Steady state dynamics of intermediate
filament networks . . . . . . . . . . . 121
N. Gabellini and
M. C. Minozzi and
A. Leon and
R. Dal Toso Nerve growth factor transcriptional
control of c-fos promoter transfected in
cultured spinal sensory neurons . . . . 131
M. Sendtner and
K. A. Stöckli and
H. Thoenen Synthesis and localization of ciliary
neurotrophic factor in the sciatic nerve
of the adult rat after lesion and during
regeneration . . . . . . . . . . . . . . 139
H. Volkmer and
B. Hassel and
J. M. Wolff and
R. Frank and
F. G. Rathjen Structure of the axonal surface
recognition molecule neurofascin and its
relationship to a neural subgroup of the
immunoglobulin superfamily . . . . . . . 149
L. Wang and
Y. Feng and
J. L. Denburg A multifunctional cell surface
developmental stage-specific antigen in
the cockroach embryo: involvement in
pathfinding by CNS pioneer axons . . . . 163
T. Frei and
F. von Bohlen und Halbach and
W. Wille and
M. Schachner Different extracellular domains of the
neural cell adhesion molecule (N-CAM)
are involved in different functions . . 177
A. C. Charles and
C. C. Naus and
D. Zhu and
G. M. Kidder and
E. R. Dirksen and
M. J. Sanderson Intercellular calcium signaling via gap
junctions in glioma cells . . . . . . . 195
M. Metsäranta and
S. Garofalo and
G. Decker and
M. Rintala and
B. de Crombrugghe and
E. Vuorio Chondrodysplasia in transgenic mice
harboring a $ 15$-amino acid deletion in
the triple helical domain of pro alpha
1(II) collagen chain . . . . . . . . . . 203
M. S. Segal and
J. M. Bye and
J. F. Sambrook and
M. J. Gething Disulfide bond formation during the
folding of influenza virus hemagglutinin 227
M. Yilla and
D. Doyle and
J. T. Sawyer Early disulfide bond formation prevents
heterotypic aggregation of membrane
proteins in a cell-free translation
system . . . . . . . . . . . . . . . . . 245
S. S. Macintyre Regulated export of a secretory protein
from the ER of the hepatocyte: a
specific binding site retaining
C-reactive protein within the ER is
downregulated during the acute phase
response . . . . . . . . . . . . . . . . 253
S. G. Miller and
L. Carnell and
H. H. Moore Post-Golgi membrane traffic: brefeldin A
inhibits export from distal Golgi
compartments to the cell surface but not
recycling . . . . . . . . . . . . . . . 267
H. Liu and
A. Bretscher Characterization of TPM1 disrupted yeast
cells indicates an involvement of
tropomyosin in directed vesicular
transport . . . . . . . . . . . . . . . 285
S. E. Lenk and
W. A. Dunn and
J. S. Trausch and
A. Ciechanover and
A. L. Schwartz Ubiquitin-activating enzyme, E1, is
associated with maturation of autophagic
vacuoles . . . . . . . . . . . . . . . . 301
S. Christgau and
H. J. Aanstoot and
H. Schierbeck and
K. Begley and
S. Tullin and
K. Hejnaes and
S. Baekkeskov Membrane anchoring of the autoantigen
GAD65 to microvesicles in pancreatic
beta-cells by palmitoylation in the
NH2-terminal domain . . . . . . . . . . 309
K. B. Kaplan and
J. R. Swedlow and
H. E. Varmus and
D. O. Morgan Association of p60c-src with endosomal
membranes in mammalian fibroblasts . . . 321
D. A. Schafer and
M. S. Mooseker and
J. A. Cooper Localization of capping protein in
chicken epithelial cells by
immunofluorescence and biochemical
fractionation . . . . . . . . . . . . . 335
Q. Zhu and
M. Clarke Association of calmodulin and an
unconventional myosin with the
contractile vacuole complex of
\bionameDictyostelium discoideum . . . . 347
F. S. Espindola and
E. M. Espreafico and
M. V. Coelho and
A. R. Martins and
F. R. Costa and
M. S. Mooseker and
R. E. Larson Biochemical and immunological
characterization of p190-calmodulin
complex from vertebrate brain: a novel
calmodulin-binding myosin . . . . . . . 359
K. L. McDonald and
E. T. O'Toole and
D. N. Mastronarde and
J. R. McIntosh Kinetochore microtubules in PTK cells 369
S. J. McConnell and
M. P. Yaffe Nuclear and mitochondrial inheritance in
yeast depends on novel cytoplasmic
structures defined by the MDM1 protein 385
B. M. Kelly and
C. S. Gillespie and
D. L. Sherman and
P. J. Brophy Schwann cells of the myelin-forming
phenotype express neurofilament protein
NF--M . . . . . . . . . . . . . . . . . 397
K. Jalink and
W. H. Moolenaar Thrombin receptor activation causes
rapid neural cell rounding and neurite
retraction independent of classic second
messengers . . . . . . . . . . . . . . . 411
A. Morla and
E. Ruoslahti A fibronectin self-assembly site
involved in fibronectin matrix assembly:
reconstruction in a synthetic peptide 421
J. Iida and
A. P. Skubitz and
L. T. Furcht and
E. A. Wayner and
J. B. McCarthy Coordinate role for cell surface
chondroitin sulfate proteoglycan and
alpha 4 beta 1 integrin in mediating
melanoma cell adhesion to fibronectin 431
K. L. Moore and
N. L. Stults and
S. Diaz and
D. F. Smith and
R. D. Cummings and
A. Varki and
R. P. McEver Identification of a specific
glycoprotein ligand for P-selectin
(CD62) on myeloid cells . . . . . . . . 445
T. W. Kuijpers and
M. Hoogerwerf and
L. J. van der Laan and
G. Nagel and
C. E. van der Schoot and
F. Grunert and
D. Roos CD66 nonspecific cross-reacting antigens
are involved in neutrophil adherence to
cytokine-activated endothelial cells . . 457
M. A. Lynch and
L. A. Staehelin Domain-specific and cell type-specific
localization of two types of cell wall
matrix polysaccharides in the clover
root tip . . . . . . . . . . . . . . . . 467
G. H. Miao and
Z. Hong and
D. P. Verma Topology and phosphorylation of soybean
nodulin-26, an intrinsic protein of the
peribacteroid membrane . . . . . . . . . 481
P. A. Walton and
S. J. Gould and
R. A. Rachubinski and
S. Subramani and
J. R. Feramisco Transport of microinjected alcohol
oxidase from Pichia pastoris into
vesicles in mammalian cells: involvement
of the peroxisomal targeting signal . . 499
A. Ostman and
J. Thyberg and
B. Westermark and
C. H. Heldin PDGF-AA and PDGF--BB biosynthesis:
proprotein processing in the Golgi
complex and lysosomal degradation of
PDGF--BB retained intracellularly . . . 509
R. Kuliawat and
P. Arvan Protein targeting via the
``constitutive-like'' secretory pathway
in isolated pancreatic islets: passive
sorting in the immature granule
compartment . . . . . . . . . . . . . . 521
M. Seeger and
G. S. Payne Selective and immediate effects of
clathrin heavy chain mutations on Golgi
membrane protein retention in
\bionameSaccharomyces cerevisiae . . . . 531
P. S. Kim and
D. Bole and
P. Arvan Transient aggregation of nascent
thyroglobulin in the endoplasmic
reticulum: relationship to the molecular
chaperone, BiP . . . . . . . . . . . . . 541
G. M. Denning and
L. S. Ostedgaard and
M. J. Welsh Abnormal localization of cystic fibrosis
transmembrane conductance regulator in
primary cultures of cystic fibrosis
airway epithelia . . . . . . . . . . . . 551
S. Chowdhury and
K. W. Smith and
M. C. Gustin Osmotic stress and the yeast
cytoskeleton: phenotype-specific
suppression of an actin mutation . . . . 561
H. Wille and
G. Drewes and
J. Biernat and
E. M. Mandelkow and
E. Mandelkow Alzheimer-like paired helical filaments
and antiparallel dimers formed from
microtubule-associated protein tau in
vitro . . . . . . . . . . . . . . . . . 573
C. Febvre-Chevalier and
J. Febvre Microtubule dissassembly in vivo:
intercalary destabilization and
breakdown of microtubules in the
heliozoan Actinocoryne contractilis . . 585
L. L. Satterwhite and
M. J. Lohka and
K. L. Wilson and
T. Y. Scherson and
L. J. Cisek and
J. L. Corden and
T. D. Pollard Phosphorylation of myosin--II regulatory
light chain by cyclin-p34cdc2: a
mechanism for the timing of cytokinesis 595
T. N. Davis A temperature-sensitive calmodulin
mutant loses viability during mitosis 607
S. E. Brockerhoff and
T. N. Davis Calmodulin concentrates at regions of
cell growth in \bionameSaccharomyces
cerevisiae . . . . . . . . . . . . . . . 619
B. B. Olwin and
A. Rapraeger Repression of myogenic differentiation
by aFGF, bFGF, and K--FGF is dependent
on cellular heparan sulfate . . . . . . 631
N. Duval and
J. Massoulié and
S. Bon H and T subunits of acetylcholinesterase
from Torpedo, expressed in COS cells,
generate all types of globular forms . . 641
P. Lamoureux and
J. Zheng and
R. E. Buxbaum and
S. R. Heidemann A cytomechanical investigation of
neurite growth on different culture
surfaces . . . . . . . . . . . . . . . . 655
J. L. Saffell and
F. S. Walsh and
P. Doherty Direct activation of second messenger
pathways mimics cell adhesion
molecule-dependent neurite outgrowth . . 663
K. A. Knudsen and
M. J. Wheelock Plakoglobin, or an 83-kD homologue
distinct from beta-catenin, interacts
with E-cadherin and N-cadherin . . . . . 671
M. Peifer and
P. D. McCrea and
K. J. Green and
E. Wieschaus and
B. M. Gumbiner The vertebrate adhesive junction
proteins beta-catenin and plakoglobin
and the \bionameDrosophila segment
polarity gene armadillo form a multigene
family with similar properties . . . . . 681
X. Sun and
K. Skorstengaard and
D. F. Mosher Disulfides modulate RGD-inhibitable cell
adhesive activity of thrombospondin . . 693
N. Matsuyoshi and
M. Hamaguchi and
S. Taniguchi and
A. Nagafuchi and
S. Tsukita and
M. Takeichi Cadherin-mediated cell--cell adhesion is
perturbed by v-src tyrosine
phosphorylation in metastatic
fibroblasts . . . . . . . . . . . . . . 703
B. A. Arrick and
A. R. Lopez and
F. Elfman and
R. Ebner and
C. H. Damsky and
R. Derynck Altered metabolic and adhesive
properties and increased tumorigenesis
associated with increased expression of
transforming growth factor beta 1 . . . 715
C. M. Alexander and
Z. Werb Targeted disruption of the tissue
inhibitor of metalloproteinases gene
increases the invasive behavior of
primitive mesenchymal cells derived from
embryonic stem cells in vitro . . . . . 727
G. R. Johnson and
T. Saeki and
A. W. Gordon and
M. Shoyab and
D. S. Salomon and
K. Stromberg Autocrine action of amphiregulin in a
colon carcinoma cell line and
immunocytochemical localization of
amphiregulin in human colon . . . . . . 741
B. C. Williams and
T. L. Karr and
J. M. Montgomery and
M. L. Goldberg The \bionameDrosophila l(1)zw10 gene
product, required for accurate mitotic
chromosome segregation, is redistributed
at anaphase onset . . . . . . . . . . . 759
B. Lüscher and
R. N. Eisenman Mitosis-specific phosphorylation of the
nuclear oncoproteins Myc and Myb . . . . 775
F. Girard and
U. Strausfeld and
J. C. Cavadore and
P. Russell and
A. Fernandez and
N. J. Lamb cdc25 is a nuclear protein expressed
constitutively throughout the cell cycle
in nontransformed mammalian cells . . . 785
T. C. Hobman and
L. Woodward and
M. G. Farquhar The rubella virus E1 glycoprotein is
arrested in a novel post--ER, pre-Golgi
compartment . . . . . . . . . . . . . . 795
J. Tooze and
M. Hollinshead In AtT20 and HeLa cells brefeldin A
induces the fusion of tubular endosomes
and changes their distribution and some
of their endocytic properties . . . . . 813
J. M. Backer and
S. E. Shoelson and
M. A. Weiss and
Q. X. Hua and
R. B. Cheatham and
E. Haring and
D. C. Cahill and
M. F. White The insulin receptor juxtamembrane
region contains two independent
tyrosine/beta-turn internalization
signals . . . . . . . . . . . . . . . . 831
M. F. Pittenger and
D. M. Helfman In vitro and in vivo characterization of
four fibroblast tropomyosins produced in
bacteria: TM-2, TM-3, TM-5a, and TM-5b
are co-localized in interphase
fibroblasts . . . . . . . . . . . . . . 841
L. Pagliaro and
D. L. Taylor $2$-Deoxyglucose and cytochalasin D
modulate aldolase mobility in living 3T3
cells . . . . . . . . . . . . . . . . . 859
S. Kamimura and
E. Mandelkow Tubulin protofilaments and
kinesin-dependent motility . . . . . . . 865
H. H. Arnold and
C. D. Gerharz and
H. E. Gabbert and
A. Salminen Retinoic acid induces myogenin synthesis
and myogenic differentiation in the rat
rhabdomyosarcoma cell line BA--Han--1C 877
G. Wolswijk and
M. Noble Cooperation between PDGF and FGF
converts slowly dividing O-2Aadult
progenitor cells to rapidly dividing
cells with characteristics of
O-2Aperinatal progenitor cells . . . . . 889
R. Flaumenhaft and
M. Abe and
P. Mignatti and
D. B. Rifkin Basic fibroblast growth factor-induced
activation of latent transforming growth
factor beta in endothelial cells:
regulation of plasminogen activator
activity . . . . . . . . . . . . . . . . 901
D. D. Schlaepfer and
H. R. Bode and
H. T. Haigler Distinct cellular expression pattern of
annexins in Hydra vulgaris . . . . . . . 911
M. E. Selsted and
S. I. Miller and
A. H. Henschen and
A. J. Ouellette Enteric defensins: antibiotic peptide
components of intestinal host defense 929
Y. Rao and
X. F. Wu and
J. Gariepy and
U. Rutishauser and
C. H. Siu Identification of a peptide sequence
involved in homophilic binding in the
neural cell adhesion molecule NCAM . . . 937
F. G. Giancotti and
M. A. Stepp and
S. Suzuki and
E. Engvall and
E. Ruoslahti Proteolytic processing of endogenous and
recombinant beta 4 integrin subunit . . 951
G. David and
B. van der Schueren and
P. Marynen and
J. J. Cassiman and
H. van den Berghe Molecular cloning of amphiglycan, a
novel integral membrane heparan sulfate
proteoglycan expressed by epithelial and
fibroblastic cells . . . . . . . . . . . 961
L. Thomas and
H. R. Byers and
J. Vink and
I. Stamenkovic CD44H regulates tumor cell migration on
hyaluronate-coated substrate . . . . . . 971
C. M. Kielty and
S. P. Whittaker and
M. E. Grant and
C. A. Shuttleworth Type VI collagen microfibrils: evidence
for a structural association with
hyaluronan . . . . . . . . . . . . . . . 979
D. M. Standiford and
J. D. Richter Analysis of a developmentally regulated
nuclear localization signal in
\bionameXenopus . . . . . . . . . . . . 991
T. V. Kurzchalia and
P. Dupree and
R. G. Parton and
R. Kellner and
H. Virta and
M. Lehnert and
K. Simons VIP21, a 21-kD membrane protein is an
integral component of
trans-Golgi-network-derived transport
vesicles . . . . . . . . . . . . . . . . 1003
M. G. Waters and
D. O. Clary and
J. E. Rothman A novel 115-kD peripheral membrane
protein is required for intercisternal
transport in the Golgi stack . . . . . . 1015
P. M. Mathews and
J. B. Martinie and
D. M. Fambrough The pathway and targeting signal for
delivery of the integral membrane
glycoprotein LEP100 to lysosomes . . . . 1027
R. Bowser and
H. Müller and
B. Govindan and
P. Novick Sec8p and Sec15p are components of a
plasma membrane-associated 19.5S
particle that may function downstream of
Sec4p to control exocytosis . . . . . . 1041
B. A. Lee and
D. J. Donoghue Intracellular retention of
membrane-anchored v-sis protein
abrogates autocrine signal transduction 1057
V. Herzog and
U. Berndorfer and
Y. Saber Isolation of insoluble secretory product
from bovine thyroid: extracellular
storage of thyroglobulin in covalently
cross-linked form . . . . . . . . . . . 1071
T. P. Hodge and
R. Cross and
J. Kendrick-Jones Role of the COOH-terminal nonhelical
tailpiece in the assembly of a
vertebrate nonmuscle myosin rod . . . . 1085
F. Verde and
M. Dogterom and
E. Stelzer and
E. Karsenti and
S. Leibler Control of microtubule dynamics and
length by cyclin A- and cyclin
B-dependent kinases in \bionameXenopus
egg extracts . . . . . . . . . . . . . . 1097
A. Devault and
D. Fesquet and
J. C. Cavadore and
A. M. Garrigues and
J. C. Labbé and
T. Lorca and
A. Picard and
M. Philippe and
M. Dorée Cyclin A potentiates
maturation-promoting factor activation
in the early \bionameXenopus embryo via
inhibition of the tyrosine kinase that
phosphorylates cdc2 . . . . . . . . . . 1109
I. Toyoshima and
H. Yu and
E. R. Steuer and
M. P. Sheetz Kinectin, a major kinesin-binding
protein on ER . . . . . . . . . . . . . 1121
B. M. Paschal and
A. Mikami and
K. K. Pfister and
R. B. Vallee Homology of the 74-kD cytoplasmic dynein
subunit with a flagellar dynein
polypeptide suggests an intracellular
targeting function . . . . . . . . . . . 1133
D. N. Mastronarde and
E. T. O'Toole and
K. L. McDonald and
J. R. McIntosh and
M. E. Porter Arrangement of inner dynein arms in
wild-type and mutant flagella of
\bionameChlamydomonas . . . . . . . . . 1145
M. E. Porter and
J. Power and
S. K. Dutcher Extragenic suppressors of paralyzed
flagellar mutations in
\bionameChlamydomonas reinhardtii
identify loci that alter the inner
dynein arms . . . . . . . . . . . . . . 1163
A. G. Moss and
J. L. Gatti and
G. B. Witman The motile beta/IC1 subunit of sea
urchin sperm outer arm dynein does not
form a rigor bond . . . . . . . . . . . 1177
A. G. Moss and
W. S. Sale and
L. A. Fox and
G. B. Witman The alpha subunit of sea urchin sperm
outer arm dynein mediates structural and
rigor binding to microtubules . . . . . 1189
K. W. Tsim and
I. Greenberg and
M. Rimer and
W. R. Randall and
M. M. Salpeter Transcripts for the acetylcholine
receptor and acetylcholine esterase show
distribution differences in cultured
chick muscle cells . . . . . . . . . . . 1201
S. W. Lee and
C. Tomasetto and
D. Paul and
K. Keyomarsi and
R. Sager Transcriptional downregulation of
gap-junction proteins blocks junctional
communication in human mammary tumor
cell lines . . . . . . . . . . . . . . . 1213
O. Carpén and
P. Pallai and
D. E. Staunton and
T. A. Springer Association of intercellular adhesion
molecule-1 (ICAM-1) with
actin-containing cytoskeleton and
alpha-actinin . . . . . . . . . . . . . 1223
M. H. Symons and
T. J. Mitchison A GTPase controls cell-substrate
adhesion in \bionameXenopus XTC
fibroblasts . . . . . . . . . . . . . . 1235
G. Kadmon and
M. Eckert and
M. Sammar and
M. Schachner and
P. Altevogt Nectadrin, the heat-stable antigen, is a
cell adhesion molecule . . . . . . . . . 1245
J. F. Kayyem and
J. M. Roman and
E. J. de la Rosa and
U. Schwarz and
W. J. Dreyer Bravo\slash Nr-CAM is closely related to
the cell adhesion molecules L1 and
Ng--CAM and has a similar heterodimer
structure . . . . . . . . . . . . . . . 1259
R. S. Talhouk and
M. J. Bissell and
Z. Werb Coordinated expression of extracellular
matrix-degrading proteinases and their
inhibitors regulates mammary epithelial
function during involution . . . . . . . 1271
E. Izaurralde and
J. Stepinski and
E. Darzynkiewicz and
I. W. Mattaj A cap binding protein that may mediate
nuclear export of RNA polymerase
II-transcribed RNAs . . . . . . . . . . 1287
P. Bell and
M. C. Dabauvalle and
U. Scheer In vitro assembly of prenucleolar bodies
in \bionameXenopus egg extract . . . . . 1297
A. P. Huovila and
A. M. Eder and
S. D. Fuller Hepatitis B surface antigen assembles in
a post--ER, pre-Golgi compartment . . . 1305
B. W. Wattenberg and
T. J. Raub and
R. R. Hiebsch and
P. J. Weidman The activity of Golgi transport vesicles
depends on the presence of the
N-ethylmaleimide-sensitive factor (NSF)
and a soluble NSF attachment protein
(alpha SNAP) during vesicle formation 1321
I. Corthésy-Theulaz and
A. Pauloin and
S. R. Pfeffer Cytoplasmic dynein participates in the
centrosomal localization of the Golgi
complex . . . . . . . . . . . . . . . . 1333
N. Ghinea and
M. T. Vu Hai and
M. T. Groyer-Picard and
A. Houllier and
D. Schoëvaërt and
E. Milgrom Pathways of internalization of the
hCG/LH receptor: immunoelectron
microscopic studies in Leydig cells and
transfected L-cells . . . . . . . . . . 1347
S. J. Roberts and
D. S. Leaf and
H. P. Moore and
J. C. Gerhart The establishment of polarized membrane
traffic in \bionameXenopus laevis
embryos . . . . . . . . . . . . . . . . 1359
T. J. O'Halloran and
R. G. Anderson Clathrin heavy chain is required for
pinocytosis, the presence of large
vacuoles, and development in
\bionameDictyostelium . . . . . . . . . 1371
P. R. Maycox and
E. Link and
A. Reetz and
S. A. Morris and
R. Jahn Clathrin-coated vesicles in nervous
tissue are involved primarily in
synaptic vesicle recycling . . . . . . . 1379
T. Mitamura and
R. Iwamoto and
T. Umata and
T. Yomo and
I. Urabe and
M. Tsuneoka and
E. Mekada The 27-kD diphtheria toxin
receptor-associated protein (DRAP27)
from vero cells is the monkey homologue
of human CD9 antigen: expression of
DRAP27 elevates the number of diphtheria
toxin receptors on toxin-sensitive cells 1389
S. Squarzoni and
P. Sabatelli and
M. C. Maltarello and
A. Cataldi and
R. di Primio and
N. M. Maraldi Localization of dystrophin COOH-terminal
domain by the fracture-label technique 1401
B. A. Danowski and
K. Imanaka-Yoshida and
J. M. Sanger and
J. W. Sanger Costameres are sites of force
transmission to the substratum in adult
rat cardiomyocytes . . . . . . . . . . . 1411
J. H. Hartwig Mechanisms of actin rearrangements
mediating platelet activation . . . . . 1421
J. Jongstra-Bilen and
P. A. Janmey and
J. H. Hartwig and
S. Galea and
J. Jongstra The lymphocyte-specific protein LSP1
binds to F-actin and to the cytoskeleton
through its COOH-terminal basic domain 1443
G. Piperno and
K. Mead and
W. Shestak The inner dynein arms I2 interact with a
``dynein regulatory complex'' in
\bionameChlamydomonas flagella . . . . . 1455
J. A. Marrs and
G. B. Bouck The two major membrane skeletal proteins
(articulins) of Euglena gracilis define
a novel class of cytoskeletal proteins 1465
P. Ouyang and
S. P. Sugrue Identification of an epithelial protein
related to the desmosome and
intermediate filament network . . . . . 1477
M. Vandromme and
C. Gauthier-Rouvi\`ere and
G. Carnac and
N. Lamb and
A. Fernandez Serum response factor p67SRF is
expressed and required during myogenic
differentiation of both mouse C2 and rat
L6 muscle cell lines . . . . . . . . . . 1489
K. A. Birch and
J. S. Pober and
G. B. Zavoico and
A. R. Means and
B. M. Ewenstein Calcium\slash calmodulin transduces
thrombin-stimulated secretion: studies
in intact and minimally permeabilized
human umbilical vein endothelial cells 1501
M. G. Lampugnani and
M. Resnati and
M. Raiteri and
R. Pigott and
A. Pisacane and
G. Houen and
L. P. Ruco and
E. Dejana A novel endothelial-specific membrane
protein is a marker of cell--cell
contacts . . . . . . . . . . . . . . . . 1511
D. J. Bidanset and
R. LeBaron and
L. Rosenberg and
J. E. Murphy-Ullrich and
M. Hook Regulation of cell substrate adhesion:
effects of small
galactosaminoglycan-containing
proteoglycans . . . . . . . . . . . . . 1523
Y. Adachi and
U. K. Laemmli Identification of nuclear
pre-replication centers poised for DNA
synthesis in \bionameXenopus egg
extracts: immunolocalization study of
replication protein A . . . . . . . . . 1
N. Ulitzur and
A. Harel and
N. Feinstein and
Y. Gruenbaum Lamin activity is essential for nuclear
envelope assembly in a
\bionameDrosophila embryo cell-free
extract . . . . . . . . . . . . . . . . 17
S. M. Cohn and
T. C. Simon and
K. A. Roth and
E. H. Birkenmeier and
J. I. Gordon Use of transgenic mice to map cis-acting
elements in the intestinal fatty acid
binding protein gene (Fabpi) that
control its cell lineage-specific and
regional patterns of expression along
the duodenal-colonic and crypt-villus
axes of the gut epithelium . . . . . . . 27
M. Meyer and
I. Matsuoka and
C. Wetmore and
L. Olson and
H. Thoenen Enhanced synthesis of brain-derived
neurotrophic factor in the lesioned
peripheral nerve: different mechanisms
are responsible for the regulation of
BDNF and NGF mRNA . . . . . . . . . . . 45
S. W. L'Hernault and
P. M. Arduengo Mutation of a putative sperm membrane
protein in \bionameCaenorhabditis
elegans prevents sperm differentiation
but not its associated meiotic divisions 55
C. J. Roberts and
S. F. Nothwehr and
T. H. Stevens Membrane protein sorting in the yeast
secretory pathway: evidence that the
vacuole may be the default compartment 69
T. Noda and
M. G. Farquhar A non-autophagic pathway for diversion
of ER secretory proteins to lysosomes 85
K. Zen and
J. Biwersi and
N. Periasamy and
A. S. Verkman Second messengers regulate endosomal
acidification in Swiss 3T3 fibroblasts 99
I. Sabolic and
F. Wuarin and
L. B. Shi and
A. S. Verkman and
D. A. Ausiello and
S. Gluck and
D. Brown Apical endosomes isolated from kidney
collecting duct principal cells lack
subunits of the proton pumping ATPase 111
R. G. Parton and
K. Simons and
C. G. Dotti Axonal and dendritic endocytic pathways
in cultured neurons . . . . . . . . . . 123
J. C. Hay and
T. F. Martin Resolution of regulated secretion into
sequential MgATP-dependent and
calcium-dependent stages mediated by
distinct cytosolic proteins . . . . . . 139
I. Van der Leij and
M. Van den Berg and
R. Boot and
M. Franse and
B. Distel and
H. F. Tabak Isolation of peroxisome assembly mutants
from \bionameSaccharomyces cerevisiae
with different morphologies using a
novel positive selection procedure . . . 153
M. C. Wagner and
B. Barylko and
J. P. Albanesi Tissue distribution and subcellular
localization of mammalian myosin I . . . 163
P. W. Baas and
H. C. Joshi Gamma-tubulin distribution in the
neuron: implications for the origins of
neuritic microtubules . . . . . . . . . 171
R. A. Meyer and
D. W. Laird and
J. P. Revel and
R. G. Johnson Inhibition of gap junction and adherens
junction assembly by connexin and A--CAM
antibodies . . . . . . . . . . . . . . . 179
V. P. Mauro and
L. A. Krushel and
B. A. Cunningham and
G. M. Edelman Homophilic and heterophilic binding
activities of Nr--CAM, a nervous system
cell adhesion molecule . . . . . . . . . 191
A. H. Zisch and
L. D'Alessandri and
B. Ranscht and
R. Falchetto and
K. H. Winterhalter and
L. Vaughan Neuronal cell adhesion molecule
contactin/F11 binds to tenascin via its
immunoglobulin-like domains . . . . . . 203
D. V. Erbe and
B. A. Wolitzky and
L. G. Presta and
C. R. Norton and
R. J. Ramos and
D. K. Burns and
J. M. Rumberger and
B. N. Rao and
C. Foxall and
B. K. Brandley Identification of an E-selectin region
critical for carbohydrate recognition
and cell adhesion . . . . . . . . . . . 215
B. Schleiffenbaum and
O. Spertini and
T. F. Tedder Soluble L-selectin is present in human
plasma at high levels and retains
functional activity . . . . . . . . . . 229
P. J. Newman and
C. A. Hillery and
R. Albrecht and
L. V. Parise and
M. C. Berndt and
A. V. Mazurov and
L. C. Dunlop and
J. Zhang and
S. E. Rittenhouse Activation-dependent changes in human
platelet PECAM-1: phosphorylation,
cytoskeletal association, and surface
membrane redistribution . . . . . . . . 239
K. F. Johnson and
S. Kornfeld The cytoplasmic tail of the mannose
$6$-phosphate/insulin-like growth
factor--II receptor has two signals for
lysosomal enzyme sorting in the Golgi 249
K. Prydz and
S. H. Hansen and
K. Sandvig and
B. van Deurs Effects of brefeldin A on endocytosis,
transcytosis and transport to the Golgi
complex in polarized MDCK cells . . . . 259
S. A. Wood and
W. J. Brown The morphology but not the function of
endosomes and lysosomes is altered by
brefeldin A . . . . . . . . . . . . . . 273
D. J. Klionsky and
R. Cueva and
D. S. Yaver Aminopeptidase I of
\bionameSaccharomyces cerevisiae is
localized to the vacuole independent of
the secretory pathway . . . . . . . . . 287
K. Takeshige and
M. Baba and
S. Tsuboi and
T. Noda and
Y. Ohsumi Autophagy in yeast demonstrated with
proteinase-deficient mutants and
conditions for its induction . . . . . . 301
S. Ganesan and
R. Calle and
K. Zawalich and
K. Greenawalt and
W. Zawalich and
G. I. Shulman and
H. Rasmussen Immunocytochemical localization of
alpha-protein kinase C in rat pancreatic
beta-cells during glucose-induced
insulin secretion . . . . . . . . . . . 313
R. Barbato and
G. Friso and
F. Rigoni and
F. Dalla Vecchia and
G. M. Giacometti Structural changes and lateral
redistribution of photosystem II during
donor side photoinhibition of thylakoids 325
M. Perrot-Applanat and
P. Lescop and
E. Milgrom The cytoskeleton and the cellular
traffic of the progesterone receptor . . 337
J. C. den Hartigh and
P. M. van Bergen en Henegouwen and
A. J. Verkleij and
J. Boonstra The EGF receptor is an actin-binding
protein . . . . . . . . . . . . . . . . 349
T. S. Khurana and
S. C. Watkins and
L. M. Kunkel The subcellular distribution of
chromosome $6$-encoded
dystrophin-related protein in the brain 357
J. A. Theriot and
T. J. Mitchison Comparison of actin and cell surface
dynamics in motile fibroblasts . . . . . 367
D. S. Sullivan and
T. C. Huffaker Astral microtubules are not required for
anaphase B in \bionameSaccharomyces
cerevisiae . . . . . . . . . . . . . . . 379
B. J. Schnapp and
T. S. Reese and
R. Bechtold Kinesin is bound with high affinity to
squid axon organelles that move to the
plus-end of microtubules . . . . . . . . 389
A. K. Wilson and
P. A. Coulombe and
E. Fuchs The roles of K5 and K14 head, tail, and
R/K L L E G E domains in keratin
filament assembly in vitro . . . . . . . 401
L. Silverman and
M. D. Resh Lysine residues form an integral
component of a novel NH2-terminal
membrane targeting motif for
myristylated pp60v-src . . . . . . . . . 415
J. L. Rodríguez Fernández and
B. Geiger and
D. Salomon and
I. Sabanay and
M. Zöller and
A. Ben-Ze'ev Suppression of tumorigenicity in
transformed cells after transfection
with vinculin cDNA . . . . . . . . . . . 427
B. S. Suh and
R. Sprengel and
I. Keren-Tal and
S. Himmelhoch and
A. Amsterdam Introduction of a gonadotropin receptor
expression plasmid into immortalized
granulosa cells leads to reconstitution
of hormone-dependent steroidogenesis . . 439
D. J. Vestal and
B. Ranscht Glycosyl phosphatidylinositol--anchored
T-cadherin mediates calcium-dependent,
homophilic cell adhesion . . . . . . . . 451
V. Gentile and
V. Thomazy and
M. Piacentini and
L. Fesus and
P. J. Davies Expression of tissue transglutaminase in
Balb--C 3T3 fibroblasts: effects on
cellular morphology and adhesion . . . . 463
M. A. Moses and
J. Sudhalter and
R. Langer Isolation and characterization of an
inhibitor of neovascularization from
scapular chondrocytes . . . . . . . . . 475
H. G. Augustin-Voss and
B. U. Pauli Migrating endothelial cells are
distinctly hyperglycosylated and express
specific migration-associated cell
surface glycoproteins . . . . . . . . . 483
Y. Gavrieli and
Y. Sherman and
S. A. Ben-Sasson Identification of programmed cell death
in situ via specific labeling of nuclear
DNA fragmentation . . . . . . . . . . . 493
C. C. Kopczynski and
M. A. Muskavitch Introns excised from the Delta primary
transcript are localized near sites of
Delta transcription . . . . . . . . . . 503
K. G. Hardwick and
H. R. Pelham SED5 encodes a 39-kD integral membrane
protein required for vesicular transport
between the ER and the Golgi complex . . 513
Y. S. Juhnn and
T. L. Jones and
A. M. Spiegel Amino- and carboxy-terminal deletion
mutants of Gs alpha are localized to the
particulate fraction of transfected COS
cells . . . . . . . . . . . . . . . . . 523
C. V. Harding and
H. J. Geuze Class II MHC molecules are present in
macrophage lysosomes and phagolysosomes
that function in the phagocytic
processing of \bionameListeria
monocytogenes for presentation to T
cells . . . . . . . . . . . . . . . . . 531
T. Masuda and
N. Fujimaki and
E. Ozawa and
H. Ishikawa Confocal laser microscopy of dystrophin
localization in guinea pig skeletal
muscle fibers . . . . . . . . . . . . . 543
K. J. Eilertsen and
T. C. Keller Identification and characterization of
two huge protein components of the brush
border cytoskeleton: evidence for a
cellular isoform of titin . . . . . . . 549
S. H. Zigmond and
R. Furukawa and
M. Fechheimer Inhibition of actin filament
depolymerization by the
\bionameDictyostelium 30,000-D
actin-bundling protein . . . . . . . . . 559
T. J. Mitchison and
E. D. Salmon Poleward kinetochore fiber movement
occurs during both metaphase and
anaphase--A in newt lung cell mitosis 569
R. E. Palmer and
D. S. Sullivan and
T. Huffaker and
D. Koshland Role of astral microtubules and actin in
spindle orientation and migration in the
budding yeast, \bionameSaccharomyces
cerevisiae . . . . . . . . . . . . . . . 583
P. N. Hoffman and
M. A. Lopata and
D. F. Watson and
R. F. Luduena Axonal transport of class II and III
beta-tubulin: evidence that the slow
component wave represents the movement
of only a small fraction of the tubulin
in mature motor axons . . . . . . . . . 595
A. Gow and
V. L. Friedrich and
R. A. Lazzarini Myelin basic protein gene contains
separate enhancers for oligodendrocyte
and Schwann cell expression . . . . . . 605
P. Adamson and
H. F. Paterson and
A. Hall Intracellular localization of the P21rho
proteins . . . . . . . . . . . . . . . . 617
F. Bussolino and
M. F. Di Renzo and
M. Ziche and
E. Bocchietto and
M. Olivero and
L. Naldini and
G. Gaudino and
L. Tamagnone and
A. Coffer and
P. M. Comoglio Hepatocyte growth factor is a potent
angiogenic factor which stimulates
endothelial cell motility and growth . . 629
S. D. Banerjee and
B. P. Toole Hyaluronan-binding protein in
endothelial cell morphogenesis . . . . . 643
K. Miyake and
Y. Hasunuma and
H. Yagita and
M. Kimoto Requirement for VLA-4 and VLA-5
integrins in lymphoma cells binding to
and migration beneath stromal cells in
culture . . . . . . . . . . . . . . . . 653
A. L. Prieto and
C. Andersson-Fisone and
K. L. Crossin Characterization of multiple adhesive
and counteradhesive domains in the
extracellular matrix protein cytotactin 663
P. Kallunki and
K. Sainio and
R. Eddy and
M. Byers and
T. Kallunki and
H. Sariola and
K. Beck and
H. Hirvonen and
T. B. Shows and
K. Tryggvason A truncated laminin chain homologous to
the B2 chain: structure, spatial
expression, and chromosomal assignment 679
M. P. Marinkovich and
G. P. Lunstrum and
D. R. Keene and
R. E. Burgeson The dermal-epidermal junction of human
skin contains a novel laminin variant 695
S. R. Wente and
M. P. Rout and
G. Blobel A new family of yeast nuclear pore
complex proteins . . . . . . . . . . . . 705
A. E. Goldman and
R. D. Moir and
M. Montag-Lowy and
M. Stewart and
R. D. Goldman Pathway of incorporation of
microinjected lamin A into the nuclear
envelope . . . . . . . . . . . . . . . . 725
I. D. Russell and
D. Tollervey NOP3 is an essential yeast protein which
is required for pre-rRNA processing . . 737
E. J. Tisdale and
J. R. Bourne and
R. Khosravi-Far and
C. J. Der and
W. E. Balch GTP-binding mutants of rab1 and rab2 are
potent inhibitors of vesicular transport
from the endoplasmic reticulum to the
Golgi complex . . . . . . . . . . . . . 749
P. Moran and
I. W. Caras Proteins containing an uncleaved signal
for glycophosphatidylinositol membrane
anchor attachment are retained in a
post--ER compartment . . . . . . . . . . 763
C. A. Vater and
C. K. Raymond and
K. Ekena and
I. Howald-Stevenson and
T. H. Stevens The VPS1 protein, a homolog of dynamin
required for vacuolar protein sorting in
\bionameSaccharomyces cerevisiae, is a
GTPase with two functionally separable
domains . . . . . . . . . . . . . . . . 773
K. A. Beck and
M. Chang and
F. M. Brodsky and
J. H. Keen Clathrin assembly protein AP-2 induces
aggregation of membrane vesicles: a
possible role for AP-2 in endosome
formation . . . . . . . . . . . . . . . 787
A. Rodríguez Del Castillo and
M. L. Vitale and
J. M. Trifaró Ca$^{2+}$ and pH determine the
interaction of chromaffin cell scinderin
with phosphatidylserine and
phosphatidylinositol 4,5,-biphosphate
and its cellular distribution during
nicotinic-receptor stimulation and
protein kinase C activation . . . . . . 797
D. Houzelstein and
G. E. Lyons and
J. Chamberlain and
M. E. Buckingham Localization of dystrophin gene
transcripts during mouse embryogenesis 811
K. A. Kellerman and
K. G. Miller An unconventional myosin heavy chain
gene from \bionameDrosophila
melanogaster . . . . . . . . . . . . . . 823
M. Way and
B. Pope and
A. G. Weeds Evidence for functional homology in the
F-actin binding domains of gelsolin and
alpha-actinin: implications for the
requirements of severing and capping . . 835
J. A. Johnston and
R. D. Sloboda A 62-kD protein required for mitotic
progression is associated with the
mitotic apparatus during M-phase and
with the nucleus during interphase . . . 843
J. A. Dent and
R. B. Cary and
J. B. Bachant and
A. Domingo and
M. W. Klymkowsky Host cell factors controlling vimentin
organization in the \bionameXenopus
oocyte . . . . . . . . . . . . . . . . . 855
A. Brown and
T. Slaughter and
M. M. Black Newly assembled microtubules are
concentrated in the proximal and distal
regions of growing axons . . . . . . . . 867
E. J. Williams and
P. Doherty and
G. Turner and
R. A. Reid and
J. J. Hemperly and
F. S. Walsh Calcium influx into neurons can solely
account for cell contact-dependent
neurite outgrowth stimulated by
transfected L1 . . . . . . . . . . . . . 883
K. Burridge and
C. E. Turner and
L. H. Romer Tyrosine phosphorylation of paxillin and
pp125FAK accompanies cell adhesion to
extracellular matrix: a role in
cytoskeletal assembly . . . . . . . . . 893
L. Lipfert and
B. Haimovich and
M. D. Schaller and
B. S. Cobb and
J. T. Parsons and
J. S. Brugge Integrin-dependent phosphorylation and
activation of the protein tyrosine
kinase pp125FAK in platelets . . . . . . 905
Y. Takada and
J. Ylänne and
D. Mandelman and
W. Puzon and
M. H. Ginsberg A point mutation of integrin beta 1
subunit blocks binding of alpha 5 beta 1
to fibronectin and invasin but not
recruitment to adhesion plaques . . . . 913
C. L. Wilson and
J. E. Schwarzbauer The alternatively spliced V region
contributes to the differential
incorporation of plasma and cellular
fibronectins into fibrin clots . . . . . 923
Y. Sugama and
C. Tiruppathi and
K. offakidevi and
T. T. Andersen and
J. W. Fenton and
A. B. Malik Thrombin-induced expression of
endothelial P-selectin and intercellular
adhesion molecule-1: a mechanism for
stabilizing neutrophil adhesion . . . . 935
K. Hayashi and
J. A. Madri and
P. D. Yurchenco Endothelial cells interact with the core
protein of basement membrane perlecan
through beta 1 and beta 3 integrins: an
adhesion modulated by glycosaminoglycan 945
G. David and
X. M. Bai and
B. Van der Schueren and
J. J. Cassiman and
H. Van den Berghe Developmental changes in heparan sulfate
expression: in situ detection with mAbs 961
F. Wang and
M. Hanske and
K. Miedema and
G. Klein and
P. Ekblom and
W. Hennig Laminin in the male germ cells of
\bionameDrosophila . . . . . . . . . . . 977
R. Quarto and
G. Campanile and
R. Cancedda and
B. Dozin Thyroid hormone, insulin, and
glucocorticoids are sufficient to
support chondrocyte differentiation to
hypertrophy: a serum-free analysis . . . 989
O. Lefebvre and
C. Wolf and
J. M. Limacher and
P. Hutin and
C. Wendling and
M. LeMeur and
P. Basset and
M. C. Rio The breast cancer-associated
stromelysin-3 gene is expressed during
mouse mammary gland apoptosis . . . . . 997
W. C. Horne and
L. Neff and
D. Chatterjee and
A. Lomri and
J. B. Levy and
R. Baron Osteoclasts express high levels of
pp60c-src in association with
intracellular membranes . . . . . . . . 1003
M. B. Sporn and
A. B. Roberts Transforming growth factor-beta: recent
progress and new challenges . . . . . . 1017
K. Shiozaki and
M. Yanagida Functional dissection of the
phosphorylated termini of fission yeast
DNA topoisomerase II . . . . . . . . . . 1023
M. F. Jantsch and
J. G. Gall Assembly and localization of the
U1-specific snRNP C protein in the
amphibian oocyte . . . . . . . . . . . . 1037
N. Imamoto and
Y. Matsuoka and
T. Kurihara and
K. Kohno and
M. Miyagi and
F. Sakiyama and
Y. Okada and
S. Tsunasawa and
Y. Yoneda Antibodies against 70-kD heat shock
cognate protein inhibit mediated nuclear
import of karyophilic proteins . . . . . 1047
E. Ralston and
Z. W. Hall Restricted distribution of mRNA produced
from a single nucleus in hybrid myotubes 1063
D. Kuhl and
T. E. Kennedy and
A. Barzilai and
E. R. Kandel Long-term sensitization training in
Aplysia leads to an increase in the
expression of BiP, the major protein
chaperon of the ER . . . . . . . . . . . 1069
R. Schwaninger and
H. Plutner and
G. M. Bokoch and
W. E. Balch Multiple GTP-binding proteins regulate
vesicular transport from the ER to Golgi
membranes . . . . . . . . . . . . . . . 1077
H. Plutner and
H. W. Davidson and
J. Saraste and
W. E. Balch Morphological analysis of protein
transport from the ER to Golgi membranes
in digitonin-permeabilized cells: role
of the P58 containing compartment . . . 1097
H. Levanony and
R. Rubin and
Y. Altschuler and
G. Galili Evidence for a novel route of wheat
storage proteins to vacuoles . . . . . . 1117
J. Blattner and
B. Swinkels and
H. Dörsam and
T. Prospero and
S. Subramani and
C. Clayton Glycosome assembly in trypanosomes:
variations in the acceptable degeneracy
of a COOH-terminal microbody targeting
signal . . . . . . . . . . . . . . . . . 1129
Y. A. Ioannou and
D. F. Bishop and
R. J. Desnick Overexpression of human
alpha-galactosidase A results in its
intracellular aggregation,
crystallization in lysosomes, and
selective secretion . . . . . . . . . . 1137
J. F. Amatruda and
D. J. Gattermeir and
T. S. Karpova and
J. A. Cooper Effects of null mutations and
overexpression of capping protein on
morphogenesis, actin distribution and
polarized secretion in yeast . . . . . . 1151
E. Smythe and
L. L. Carter and
S. L. Schmid Cytosol- and clathrin-dependent
stimulation of endocytosis in vitro by
purified adaptors . . . . . . . . . . . 1163
M. J. Schell and
M. Maurice and
B. Stieger and
A. L. Hubbard 5'nucleotidase is sorted to the apical
domain of hepatocytes via an indirect
route . . . . . . . . . . . . . . . . . 1173
V. Straub and
R. E. Bittner and
J. J. Léger and
T. Voit Direct visualization of the dystrophin
network on skeletal muscle fiber
membrane . . . . . . . . . . . . . . . . 1183
I. C. Baines and
H. Brzeska and
E. D. Korn Differential localization of
\bionameAcanthamoeba myosin I isoforms 1193
M. A. Postner and
K. G. Miller and
E. F. Wieschaus Maternal effect mutations of the sponge
locus affect actin cytoskeletal
rearrangements in \bionameDrosophila
melanogaster embryos . . . . . . . . . . 1205
A. K. Lewis and
P. C. Bridgman Nerve growth cone lamellipodia contain
two populations of actin filaments that
differ in organization and polarity . . 1219
K. L. Taneja and
L. M. Lifshitz and
F. S. Fay and
R. H. Singer Poly(A) RNA codistribution with
microfilaments: evaluation by in situ
hybridization and quantitative digital
imaging microscopy . . . . . . . . . . . 1245
L. Cassimeris and
D. Safer and
V. T. Nachmias and
S. H. Zigmond Thymosin beta 4 sequesters the majority
of G-actin in resting human
polymorphonuclear leukocytes . . . . . . 1261
N. R. Gliksman and
S. F. Parsons and
E. D. Salmon Okadaic acid induces interphase to
mitotic-like microtubule dynamic
instability by inactivating rescue . . . 1271
C. J. Hogan and
L. Stephens and
T. Shimizu and
W. Z. Cande Physiological evidence for involvement
of a kinesin-related protein during
anaphase spindle elongation in diatom
central spindles . . . . . . . . . . . . 1277
H. Aizawa and
Y. Sekine and
R. Takemura and
Z. Zhang and
M. Nangaku and
N. Hirokawa Kinesin family in murine central nervous
system . . . . . . . . . . . . . . . . . 1287
M. J. Levis and
H. R. Bourne Activation of the alpha subunit of Gs in
intact cells alters its abundance, rate
of degradation, and membrane avidity . . 1297
S. C. Mueller and
Y. Yeh and
W. T. Chen Tyrosine phosphorylation of membrane
proteins mediates cellular invasion by
transformed cells . . . . . . . . . . . 1309
C. Koseki and
D. Herzlinger and
Q. al-Awqati Apoptosis in metanephric development . . 1327
T. Lallier and
M. Bronner-Fraser Alpha 1 beta 1 integrin on neural crest
cells recognizes some laminin substrata
in a Ca(2+)-independent manner . . . . . 1335
C. M. Regen and
A. F. Horwitz Dynamics of beta 1 integrin-mediated
adhesive contacts in motile fibroblasts 1347
K. Niederreither and
R. N. D'Souza and
B. de Crombrugghe Minimal DNA sequences that control the
cell lineage-specific expression of the
pro alpha 2(I) collagen promoter in
transgenic mice . . . . . . . . . . . . 1361
R. I. Pennell and
L. Janniche and
G. N. Scofield and
H. Booij and
S. C. de Vries and
K. Roberts Identification of a transitional cell
state in the developmental pathway to
carrot somatic embryogenesis . . . . . . 1371
P. Sonderegger and
F. G. Rathjen Regulation of axonal growth in the
vertebrate nervous system by
interactions between glycoproteins
belonging to two subgroups of the
immunoglobulin superfamily . . . . . . . 1387
J. R. Monck and
J. M. Fernandez The exocytotic fusion pore . . . . . . . 1395
D. W. Rose and
G. McCabe and
J. R. Feramisco and
M. Adler Expression of c-fos and AP-1 activity in
senescent human fibroblasts is not
sufficient for DNA synthesis . . . . . . 1405
K. Yoda and
K. Kitagawa and
H. Masumoto and
Y. Muro and
T. Okazaki A human centromere protein, CENP--B, has
a DNA binding domain containing four
potential alpha helices at the NH2
terminus, which is separable from
dimerizing activity . . . . . . . . . . 1413
M. W. Goldberg and
T. D. Allen High resolution scanning electron
microscopy of the nuclear envelope:
demonstration of a new, regular, fibrous
lattice attached to the baskets of the
nucleoplasmic face of the nuclear pores 1429
R. W. Wozniak and
G. Blobel The single transmembrane segment of
gp210 is sufficient for sorting to the
pore membrane domain of the nuclear
envelope . . . . . . . . . . . . . . . . 1441
H. M. McBride and
D. G. Millar and
J. M. Li and
G. C. Shore A signal-anchor sequence selective for
the mitochondrial outer membrane . . . . 1451
A. Cooper and
H. Bussey Yeast Kex1p is a Golgi-associated
membrane protein: deletions in a
cytoplasmic targeting domain result in
mislocalization to the vacuolar membrane 1459
B. Conradt and
J. Shaw and
T. Vida and
S. Emr and
W. Wickner In vitro reactions of vacuole
inheritance in \bionameSaccharomyces
cerevisiae . . . . . . . . . . . . . . . 1469
J. A. Gormley and
R. J. Howard and
T. F. Taraschi Trafficking of malarial proteins to the
host cell cytoplasm and erythrocyte
surface membrane involves multiple
pathways . . . . . . . . . . . . . . . . 1481
O. Staub and
F. Verrey and
T. R. Kleyman and
D. J. Benos and
B. C. Rossier and
J. P. Kraehenbuhl Primary structure of an apical protein
from \bionameXenopus laevis that
participates in amiloride-sensitive
sodium channel activity . . . . . . . . 1497
T. Fujimoto and
S. Nakade and
A. Miyawaki and
K. Mikoshiba and
K. Ogawa Localization of inositol
1,4,5-trisphosphate receptor-like
protein in plasmalemmal caveolae . . . . 1507
D. Sugden and
S. J. Rowe Protein kinase C activation antagonizes
melatonin-induced pigment aggregation in
\bionameXenopus laevis melanophores . . 1515
J. Warmke and
M. Yamakawa and
J. Molloy and
S. Falkenthal and
D. Maughan Myosin light chain-2 mutation affects
flight, wing beat frequency, and
indirect flight muscle contraction
kinetics in \bionameDrosophila . . . . . 1523
E. M. Espreafico and
R. E. Cheney and
M. Matteoli and
A. A. Nascimento and
P. V. De Camilli and
R. E. Larson and
M. S. Mooseker Primary structure and cellular
localization of chicken brain myosin--V
(p190), an unconventional myosin with
calmodulin light chains . . . . . . . . 1541
V. M. Fowler and
E. J. Adam Spectrin redistributes to the cytosol
and is phosphorylated during mitosis in
cultured cells . . . . . . . . . . . . . 1559
I. Sadler and
A. W. Crawford and
J. W. Michelsen and
M. C. Beckerle Zyxin and cCRP: two interactive LIM
domain proteins associated with the
cytoskeleton . . . . . . . . . . . . . . 1573
R. D. Vale and
F. Malik and
D. Brown Directional instability of microtubule
transport in the presence of kinesin and
dynein, two opposite polarity motor
proteins . . . . . . . . . . . . . . . . 1589
M. P. Koonce and
P. M. Grissom and
J. R. McIntosh Dynein from \bionameDictyostelium:
primary structure comparisons between a
cytoplasmic motor enzyme and flagellar
dynein . . . . . . . . . . . . . . . . . 1597
K. A. Johnson and
J. L. Rosenbaum Polarity of flagellar assembly in
\bionameChlamydomonas . . . . . . . . . 1605
B. E. Taillon and
S. A. Adler and
J. P. Suhan and
J. W. Jarvik Mutational analysis of centrin: an
EF-hand protein associated with three
distinct contractile fibers in the basal
body apparatus of \bionameChlamydomonas 1613
G. H. Sun and
A. Hirata and
Y. Ohya and
Y. Anraku Mutations in yeast calmodulin cause
defects in spindle pole body functions
and nuclear integrity . . . . . . . . . 1625
B. T. Livingston and
F. H. Wilt Phorbol esters alter cell fate during
development of sea urchin embryos . . . 1641
T. C. Cheng and
T. A. Hanley and
J. Mudd and
J. P. Merlie and
E. N. Olson Mapping of myogenin transcription during
embryogenesis using transgenes linked to
the myogenin control region . . . . . . 1649
S. G. Rossi and
R. L. Rotundo Cell surface acetylcholinesterase
molecules on multinucleated myotubes are
clustered over the nucleus of origin . . 1657
P. W. Mesner and
T. R. Winters and
S. H. Green Nerve growth factor withdrawal-induced
cell death in neuronal PC12 cells
resembles that in sympathetic neurons 1669
M. R. al-Ubaidi and
R. L. Font and
A. B. Quiambao and
M. J. Keener and
G. I. Liou and
P. A. Overbeek and
W. Baehr Bilateral retinal and brain tumors in
transgenic mice expressing simian virus
40 large T antigen under control of the
human interphotoreceptor
retinoid-binding protein promoter . . . 1681
M. L. Chiu and
J. C. Jones and
E. J. O'Keefe Restricted tissue distribution of a
37-kD possible adherens junction protein 1689
S. Kargman and
P. J. Vickers and
J. F. Evans A23187-induced translocation of
$5$-lipoxygenase in osteosarcoma cells 1701
Q. He and
J. Lesley and
R. Hyman and
K. Ishihara and
P. W. Kincade Molecular isoforms of murine CD44 and
evidence that the membrane proximal
domain is not critical for hyaluronate
recognition . . . . . . . . . . . . . . 1711
V. M. Paralkar and
B. S. Weeks and
Y. M. Yu and
H. K. Kleinman and
A. H. Reddi Recombinant human bone morphogenetic
protein 2B stimulates PC12 cell
differentiation: potentiation and
binding to type IV collagen . . . . . . 1721
L. S. Goldstein Functional redundancy in mitotic force
generation . . . . . . . . . . . . . . . 1
T. Nilsson and
M. Pypaert and
M. H. Hoe and
P. Slusarewicz and
E. G. Berger and
G. Warren Overlapping distribution of two
glycosyltransferases in the Golgi
apparatus of HeLa cells . . . . . . . . 5
E. B. Cluett and
S. A. Wood and
M. Banta and
W. J. Brown Tubulation of Golgi membranes in vivo
and in vitro in the absence of brefeldin
A . . . . . . . . . . . . . . . . . . . 15
G. M. Lee and
F. Zhang and
A. Ishihara and
C. L. McNeil and
K. A. Jacobson Unconfined lateral diffusion and an
estimate of pericellular matrix
viscosity revealed by measuring the
mobility of gold-tagged lipids . . . . . 25
L. L. Carter and
T. E. Redelmeier and
L. A. Woollenweber and
S. L. Schmid Multiple GTP-binding proteins
participate in clathrin-coated
vesicle-mediated endocytosis . . . . . . 37
J. S. Peeler and
W. C. Donzell and
R. G. Anderson The appendage domain of the AP-2 subunit
is not required for assembly or
invagination of clathrin-coated pits . . 47
S. Raths and
J. Rohrer and
F. Crausaz and
H. Riezman end3 and end4: two mutants defective in
receptor-mediated and fluid-phase
endocytosis in \bionameSaccharomyces
cerevisiae . . . . . . . . . . . . . . . 55
S. Méresse and
B. Hoflack Phosphorylation of the
cation-independent mannose $6$-phosphate
receptor is closely associated with its
exit from the trans-Golgi network . . . 67
C. E. Futter and
S. Felder and
J. Schlessinger and
A. Ullrich and
C. R. Hopkins Annexin I is phosphorylated in the
multivesicular body during the
processing of the epidermal growth
factor receptor . . . . . . . . . . . . 77
H. Masui and
L. Castro and
J. Mendelsohn Consumption of EGF by A431 cells:
evidence for receptor recycling . . . . 85
J. L. Brodsky and
S. Hamamoto and
D. Feldheim and
R. Schekman Reconstitution of protein translocation
from solubilized yeast membranes reveals
topologically distinct roles for BiP and
cytosolic Hsc70 . . . . . . . . . . . . 95
D. J. Schnell and
G. Blobel Identification of intermediates in the
pathway of protein import into
chloroplasts and their localization to
envelope contact sites . . . . . . . . . 103
K. R. Fath and
D. R. Burgess Golgi-derived vesicles from developing
epithelial cells bind actin filaments
and possess myosin--I as a
cytoplasmically oriented peripheral
membrane protein . . . . . . . . . . . . 117
M. Algrain and
O. Turunen and
A. Vaheri and
D. Louvard and
M. Arpin Ezrin contains cytoskeleton and membrane
binding domains accounting for its
proposed role as a membrane-cytoskeletal
linker . . . . . . . . . . . . . . . . . 129
R. Ding and
K. L. McDonald and
J. R. McIntosh Three-dimensional reconstruction and
analysis of mitotic spindles from the
yeast, \bionameSchizosaccharomyces pombe 141
M. J. O'Connell and
P. B. Meluh and
M. D. Rose and
N. R. Morris Suppression of the bimC4 mitotic spindle
defect by deletion of klpA, a gene
encoding a KAR3-related kinesin-like
protein in Aspergillus nidulans . . . . 153
E. L. de Hostos and
C. Rehfuess and
B. Bradtke and
D. R. Waddell and
R. Albrecht and
J. Murphy and
G. Gerisch \bionameDictyostelium mutants lacking
the cytoskeletal protein coronin are
defective in cytokinesis and cell
motility . . . . . . . . . . . . . . . . 163
H. P. Kao and
J. R. Abney and
A. S. Verkman Determinants of the translational
mobility of a small solute in cell
cytoplasm . . . . . . . . . . . . . . . 175
L. P. Baker and
H. B. Peng Tyrosine phosphorylation and
acetylcholine receptor cluster formation
in cultured \bionameXenopus muscle cells 185
H. B. Peng and
L. P. Baker and
Z. Dai A role of tyrosine phosphorylation in
the formation of acetylcholine receptor
clusters induced by electric fields in
cultured \bionameXenopus muscle cells 197
R. P. Weinberger and
R. C. Henke and
O. Tolhurst and
P. L. Jeffrey and
P. Gunning Induction of neuron-specific tropomyosin
mRNAs by nerve growth factor is
dependent on morphological
differentiation . . . . . . . . . . . . 205
A. A. Dlugosz and
S. H. Yuspa Coordinate changes in gene expression
which mark the spinous to granular cell
transition in epidermis are regulated by
protein kinase C . . . . . . . . . . . . 217
K. H. Heider and
M. Hofmann and
E. Hors and
F. van den Berg and
H. Ponta and
P. Herrlich and
S. T. Pals A human homologue of the rat
metastasis-associated variant of CD44 is
expressed in colorectal carcinomas and
adenomatous polyps . . . . . . . . . . . 227
A. van de Stolpe and
M. Karperien and
C. W. Löwik and
H. Jüppner and
G. V. Segre and
A. B. Abou-Samra and
S. W. de Laat and
L. H. Defize Parathyroid hormone-related peptide as
an endogenous inducer of parietal
endoderm differentiation . . . . . . . . 235
S. D. Robinson and
A. B. Roberts and
C. W. Daniel TGF beta suppresses casein synthesis in
mouse mammary explants and may play a
role in controlling milk levels during
pregnancy . . . . . . . . . . . . . . . 245
C. H. Streuli and
C. Schmidhauser and
M. Kobrin and
M. J. Bissell and
R. Derynck Extracellular matrix regulates
expression of the TGF-beta 1 gene . . . 253
N. Tawil and
P. Wilson and
S. Carbonetto Integrins in point contacts mediate cell
spreading: factors that regulate
integrin accumulation in point contacts
vs. focal contacts . . . . . . . . . . . 261
J. Sommerville and
J. Baird and
B. M. Turner Histone H4 acetylation and transcription
in amphibian chromatin . . . . . . . . . 277
J. A. Powers and
J. C. Eissenberg Overlapping domains of the
heterochromatin-associated protein HP1
mediate nuclear localization and
heterochromatin binding . . . . . . . . 291
B. F. McEwen and
J. T. Arena and
J. Frank and
C. L. Rieder Structure of the colcemid-treated PtK1
kinetochore outer plate as determined by
high voltage electron microscopic
tomography . . . . . . . . . . . . . . . 301
M. Ren and
G. Drivas and
P. D'Eustachio and
M. G. Rush Ran\slash TC4: a small nuclear
GTP-binding protein that regulates DNA
synthesis . . . . . . . . . . . . . . . 313
B. L. Tang and
S. H. Wong and
X. L. Qi and
S. H. Low and
W. Hong Molecular cloning, characterization,
subcellular localization and dynamics of
p23, the mammalian KDEL receptor . . . . 325
B. A. Burleigh and
C. W. Wells and
M. W. Clarke and
P. R. Gardiner An integral membrane glycoprotein
associated with an endocytic compartment
of Trypanosoma vivax: identification and
partial characterization . . . . . . . . 339
L. A. Hannan and
M. P. Lisanti and
E. Rodriguez-Boulan and
M. Edidin Correctly sorted molecules of a
GPI-anchored protein are clustered and
immobile when they arrive at the apical
surface of MDCK cells . . . . . . . . . 353
R. Zhang and
W. Skach and
H. Hasegawa and
A. N. van Hoek and
A. S. Verkman Cloning, functional analysis and cell
localization of a kidney proximal tubule
water transporter homologous to CHIP28 359
S. Nielsen and
B. L. Smith and
E. I. Christensen and
M. A. Knepper and
P. Agre CHIP28 water channels are localized in
constitutively water-permeable segments
of the nephron . . . . . . . . . . . . . 371
S. Krishna and
G. Cowan and
J. C. Meade and
R. A. Wells and
J. R. Stringer and
K. J. Robson A family of cation ATPase-like molecules
from Plasmodium falciparum . . . . . . . 385
E. Ralston Changes in architecture of the Golgi
complex and other subcellular organelles
during myogenesis . . . . . . . . . . . 399
V. M. Fowler and
M. A. Sussmann and
P. G. Miller and
B. E. Flucher and
M. P. Daniels Tropomodulin is associated with the free
(pointed) ends of the thin filaments in
rat skeletal muscle . . . . . . . . . . 411
A. L. Moon and
P. A. Janmey and
K. A. Louie and
D. G. Drubin Cofilin is an essential component of the
yeast cortical cytoskeleton . . . . . . 421
S. Yonemura and
A. Nagafuchi and
N. Sato and
S. Tsukita Concentration of an integral membrane
protein, CD43 (leukosialin,
sialophorin), in the cleavage furrow
through the interaction of its
cytoplasmic domain with actin-based
cytoskeletons . . . . . . . . . . . . . 437
T. Umeyama and
S. Okabe and
Y. Kanai and
N. Hirokawa Dynamics of microtubules bundled by
microtubule associated protein 2C
(MAP2C) . . . . . . . . . . . . . . . . 451
G. S. Bloom and
B. W. Richards and
P. L. Leopold and
D. M. Ritchey and
S. T. Brady GTP gamma S inhibits organelle transport
along axonal microtubules . . . . . . . 467
Y. Zhong and
T. Saitoh and
T. Minase and
N. Sawada and
K. Enomoto and
M. Mori Monoclonal antibody 7H6 reacts with a
novel tight junction-associated protein
distinct from ZO-1, cingulin and ZO-2 477
E. Bloch-Gallego and
I. Le Roux and
A. H. Joliot and
M. Volovitch and
C. E. Henderson and
A. Prochiantz Antennapedia homeobox peptide enhances
growth and branching of embryonic
chicken motoneurons in vitro . . . . . . 485
N. A. Wall and
M. Blessing and
C. V. Wright and
B. L. Hogan Biosynthesis and in vivo localization of
the decapentaplegic--Vg--related
protein, DVR-6 (bone morphogenetic
protein-6) . . . . . . . . . . . . . . . 493
F. Widmer and
P. Caroni Phosphorylation-site mutagenesis of the
growth-associated protein GAP-43
modulates its effects on cell spreading
and morphology . . . . . . . . . . . . . 503
G. P. Tuszynski and
V. L. Rothman and
M. Papale and
B. K. Hamilton and
J. Eyal Identification and characterization of a
tumor cell receptor for CSVTCG, a
thrombospondin adhesive domain . . . . . 513
B. E. Symington and
Y. Takada and
W. G. Carter Interaction of integrins alpha 3 beta 1
and alpha 2 beta 1: potential role in
keratinocyte intercellular adhesion . . 523
B. M. Chan and
M. E. Hemler Multiple functional forms of the
integrin VLA-2 can be derived from a
single alpha 2 cDNA clone:
interconversion of forms induced by an
anti-beta 1 antibody . . . . . . . . . . 537
M. S. Diamond and
T. A. Springer A subpopulation of Mac-1 (CD11b/CD18)
molecules mediates neutrophil adhesion
to ICAM-1 and fibrinogen . . . . . . . . 545
J. C. Brown and
K. Mann and
H. Wiedemann and
R. Timpl Structure and binding properties of
collagen type XIV isolated from human
placenta . . . . . . . . . . . . . . . . 557
R. L. Juliano and
S. Haskill Signal transduction from the
extracellular matrix . . . . . . . . . . 577
C. T. Wu Transvection, nuclear structure, and
chromatin proteins . . . . . . . . . . . 587
Y. Hiraoka and
A. F. Dernburg and
S. J. Parmelee and
M. C. Rykowski and
D. A. Agard and
J. W. Sedat The onset of homologous chromosome
pairing during \bionameDrosophila
melanogaster embryogenesis . . . . . . . 591
T. Hirano and
T. J. Mitchison Topoisomerase II does not play a
scaffolding role in the organization of
mitotic chromosomes assembled in
\bionameXenopus egg extracts . . . . . . 601
P. Hartl and
J. Gottesfeld and
D. J. Forbes Mitotic repression of transcription in
vitro . . . . . . . . . . . . . . . . . 613
E. Shtivelman and
J. M. Bishop The human gene AHNAK encodes a large
phosphoprotein located primarily in the
nucleus . . . . . . . . . . . . . . . . 625
S. Smith and
G. Blobel The first membrane spanning region of
the lamin B receptor is sufficient for
sorting to the inner nuclear membrane 631
R. Klemenz and
A. C. Andres and
E. Fröhli and
R. Schäfer and
A. Aoyama Expression of the murine small heat
shock proteins hsp 25 and alpha B
crystallin in the absence of stress . . 639
A. de Silva and
I. Braakman and
A. Helenius Posttranslational folding of vesicular
stomatitis virus G protein in the ER:
involvement of noncovalent and covalent
complexes . . . . . . . . . . . . . . . 647
K. Kodukula and
L. D. Gerber and
R. Amthauer and
L. Brink and
S. Udenfriend Biosynthesis of
glycosylphosphatidylinositol
(GPI)-anchored membrane proteins in
intact cells: specific amino acid
requirements adjacent to the site of
cleavage and GPI attachment . . . . . . 657
F. Kragler and
A. Langeder and
J. Raupachova and
M. Binder and
A. Hartig Two independent peroxisomal targeting
signals in catalase A of
\bionameSaccharomyces cerevisiae . . . . 665
M. Wendland and
S. Subramani Cytosol-dependent peroxisomal protein
import in a permeabilized cell system 675
C. L. Nehme and
M. M. Cesario and
D. G. Myles and
D. E. Koppel and
J. R. Bartles Breaching the diffusion barrier that
compartmentalizes the transmembrane
glycoprotein CE9 to the posterior-tail
plasma membrane domain of the rat
spermatozoon . . . . . . . . . . . . . . 687
T. A. Gottlieb and
I. E. Ivanov and
M. Adesnik and
D. D. Sabatini Actin microfilaments play a critical
role in endocytosis at the apical but
not the basolateral surface of polarized
epithelial cells . . . . . . . . . . . . 695
T. Funatsu and
E. Kono and
H. Higuchi and
S. Kimura and
S. Ishiwata and
T. Yoshioka and
K. Maruyama and
S. Tsukita Elastic filaments in situ in cardiac
muscle: deep-etch replica analysis in
combination with selective removal of
actin and myosin filaments . . . . . . . 711
K. Ersfeld and
J. Wehland and
U. Plessmann and
H. Dodemont and
V. Gerke and
K. Weber Characterization of the tubulin-tyrosine
ligase . . . . . . . . . . . . . . . . . 725
C. J. Horst and
G. B. Witman ptx1, a nonphototactic mutant of
\bionameChlamydomonas, lacks control of
flagellar dominance . . . . . . . . . . 733
M. Blessing and
U. Rüther and
W. W. Franke Ectopic synthesis of epidermal
cytokeratins in pancreatic islet cells
of transgenic mice interferes with
cytoskeletal order and insulin
production . . . . . . . . . . . . . . . 743
J. Behrens and
L. Vakaet and
R. Friis and
E. Winterhager and
F. Van Roy and
M. M. Mareel and
W. Birchmeier Loss of epithelial differentiation and
gain of invasiveness correlates with
tyrosine phosphorylation of the
E-cadherin/beta-catenin complex in cells
transformed with a temperature-sensitive
v--SRC gene . . . . . . . . . . . . . . 757
B. Boyer and
J. P. Thiery Cyclic AMP distinguishes between two
functions of acidic FGF in a rat bladder
carcinoma cell line . . . . . . . . . . 767
M. Fuortes and
W. W. Jin and
C. Nathan Adhesion-dependent protein tyrosine
phosphorylation in neutrophils treated
with tumor necrosis factor . . . . . . . 777
S. P. Colgan and
C. A. Parkos and
C. Delp and
M. A. Arnaout and
J. L. Madara Neutrophil migration across cultured
intestinal epithelial monolayers is
modulated by epithelial exposure to
IFN-gamma in a highly polarized fashion 785
A. Streit and
C. Nolte and
T. Rásony and
M. Schachner Interaction of astrochondrin with
extracellular matrix components and its
involvement in astrocyte process
formation and cerebellar granule cell
migration . . . . . . . . . . . . . . . 799
M. Grumet and
A. Flaccus and
R. U. Margolis Functional characterization of
chondroitin sulfate proteoglycans of
brain: interactions with neurons and
neural cell adhesion molecules . . . . . 815
C. B. Knudson Hyaluronan receptor-directed assembly of
chondrocyte pericellular matrix . . . . 825
M. Carmo-Fonseca and
J. Ferreira and
A. I. Lamond Assembly of snRNP-containing coiled
bodies is regulated in interphase and
mitosis--evidence that the coiled body
is a kinetic nuclear structure . . . . . 841
A. J. Savitz and
D. I. Meyer $ 180$-kD ribosome receptor is essential
for both ribosome binding and protein
translocation . . . . . . . . . . . . . 853
N. K. Pryer and
N. R. Salama and
R. Schekman and
C. A. Kaiser Cytosolic Sec13p complex is required for
vesicle formation from the endoplasmic
reticulum in vitro . . . . . . . . . . . 865
N. Liu and
D. T. Brown Transient translocation of the
cytoplasmic (endo) domain of a type I
membrane glycoprotein into cellular
membranes . . . . . . . . . . . . . . . 877
G. M. Griffiths and
S. Isaaz Granzymes A and B are targeted to the
lytic granules of lymphocytes by the
mannose-$6$-phosphate receptor . . . . . 885
C. Rabouille and
G. J. Strous and
J. D. Crapo and
H. J. Geuze and
J. W. Slot The differential degradation of two
cytosolic proteins as a tool to monitor
autophagy in hepatocytes by
immunocytochemistry . . . . . . . . . . 897
C. P. Chia and
A. Shariff and
S. A. Savage and
E. J. Luna The integral membrane protein,
ponticulin, acts as a monomer in
nucleating actin assembly . . . . . . . 909
F. Gittes and
B. Mickey and
J. Nettleton and
J. Howard Flexural rigidity of microtubules and
actin filaments measured from thermal
fluctuations in shape . . . . . . . . . 923
E. Shelden and
P. Wadsworth Observation and quantification of
individual microtubule behavior in vivo:
microtubule dynamics are cell-type
specific . . . . . . . . . . . . . . . . 935
D. A. Compton and
D. W. Cleveland NuMA is required for the proper
completion of mitosis . . . . . . . . . 947
P. M. Mirabito and
N. R. Morris BIMA, a TPR-containing protein required
for mitosis, localizes to the spindle
pole body in Aspergillus nidulans . . . 959
A. O. Jorgensen and
A. C. Shen and
W. Arnold and
P. S. McPherson and
K. P. Campbell The Ca$^{2+}$-release channel/ryanodine
receptor is localized in junctional and
corbular sarcoplasmic reticulum in
cardiac muscle . . . . . . . . . . . . . 969
P. Boukamp and
N. E. Fusenig ''Trans-differentiation'' from epidermal
to mesenchymal/myogenic phenotype is
associated with a drastic change in
cell--cell and cell-matrix adhesion
molecules . . . . . . . . . . . . . . . 981
R. Flaumenhaft and
M. Abe and
Y. Sato and
K. Miyazono and
J. Harpel and
C. H. Heldin and
D. B. Rifkin Role of the latent TGF-beta binding
protein in the activation of latent
TGF-beta by co-cultures of endothelial
and smooth muscle cells . . . . . . . . 995
M. A. Schwartz Spreading of human endothelial cells on
fibronectin or vitronectin triggers
elevation of intracellular free calcium 1003
G. Murugesan and
G. M. Chisolm and
P. L. Fox Oxidized low density lipoprotein
inhibits the migration of aortic
endothelial cells in vitro . . . . . . . 1011
C. Gachet and
D. Hanau and
D. Spehner and
C. Brisson and
J. C. Garaud and
D. A. Schmitt and
P. Ohlmann and
J. P. Cazenave Alpha IIb beta 3 integrin dissociation
induced by EDTA results in morphological
changes of the platelet
surface-connected canalicular system
with differential location of the two
separate subunits . . . . . . . . . . . 1021
M. S. Diamond and
J. Garcia-Aguilar and
J. K. Bickford and
A. L. Corbi and
T. A. Springer The I domain is a major recognition site
on the leukocyte integrin Mac-1
(CD11b/CD18) for four distinct adhesion
ligands . . . . . . . . . . . . . . . . 1031
S. C. Evans and
L. C. Lopez and
B. D. Shur Dominant negative mutation in cell
surface beta 1,4-galactosyltransferase
inhibits cell--cell and cell-matrix
interactions . . . . . . . . . . . . . . 1045
J. Lawler and
M. Duquette and
C. A. Whittaker and
J. C. Adams and
K. McHenry and
D. W. DeSimone Identification and characterization of
thrombospondin-4, a new member of the
thrombospondin gene family . . . . . . . 1059
H. P. Erickson Gene knockouts of c-src, transforming
growth factor beta 1, and tenascin
suggest superfluous, nonfunctional
expression of proteins . . . . . . . . . 1079
C. A. Cooke and
D. P. Bazett-Jones and
W. C. Earnshaw and
J. B. Rattner Mapping DNA within the mammalian
kinetochore . . . . . . . . . . . . . . 1083
B. Soullam and
H. J. Worman The amino-terminal domain of the lamin B
receptor is a nuclear envelope targeting
signal . . . . . . . . . . . . . . . . . 1093
C. R. Brown and
R. L. Martin and
W. J. Hansen and
R. P. Beckmann and
W. J. Welch The constitutive and stress inducible
forms of hsp 70 exhibit functional
similarities and interact with one
another in an ATP-dependent fashion . . 1101
D. Zopf and
H. D. Bernstein and
P. Walter GTPase domain of the 54-kD subunit of
the mammalian signal recognition
particle is required for protein
translocation but not for signal
sequence binding . . . . . . . . . . . . 1113
J. S. Humphrey and
P. J. Peters and
L. C. Yuan and
J. S. Bonifacino Localization of TGN38 to the trans-Golgi
network: involvement of a cytoplasmic
tyrosine-containing sequence . . . . . . 1123
M. C. Moschella and
A. R. Marks Inositol 1,4,5-trisphosphate receptor
expression in cardiac myocytes . . . . . 1137
T. Fujimoto Calcium pump of the plasma membrane is
localized in caveolae . . . . . . . . . 1147
A. J. North and
B. Galazkiewicz and
T. J. Byers and
J. R. Glenney and
J. V. Small Complementary distributions of vinculin
and dystrophin define two distinct
sarcolemma domains in smooth muscle . . 1159
M. Fechheimer and
R. Furukawa A 27,000-D core of the
\bionameDictyostelium 34,000-D protein
retains Ca(2+)-regulated actin
cross-linking but lacks bundling
activity . . . . . . . . . . . . . . . . 1169
S. Okabe and
N. Hirokawa Do photobleached fluorescent
microtubules move?: re-evaluation of
fluorescence laser photobleaching both
in vitro and in growing \bionameXenopus
axon . . . . . . . . . . . . . . . . . . 1177
K. Kishi and
T. Sasaki and
S. Kuroda and
T. Itoh and
Y. Takai Regulation of cytoplasmic division of
\bionameXenopus embryo by rho p21 and
its inhibitory GDP/GTP exchange protein
(rho GDI) . . . . . . . . . . . . . . . 1187
I. Daar and
N. Yew and
G. F. Vande Woude Inhibition of mos-induced oocyte
maturation by protein kinase A . . . . . 1197
K. Kuchler and
H. G. Dohlman and
J. Thorner The $a$-factor transporter (STE6 gene
product) and cell polarity in the yeast
\bionameSaccharomyces cerevisiae . . . . 1203
H. McNeill and
T. A. Ryan and
S. J. Smith and
W. J. Nelson Spatial and temporal dissection of
immediate and early events following
cadherin-mediated epithelial cell
adhesion . . . . . . . . . . . . . . . . 1217
D. V. Erbe and
S. R. Watson and
L. G. Presta and
B. A. Wolitzky and
C. Foxall and
B. K. Brandley and
L. A. Lasky P- and E-selectin use common sites for
carbohydrate ligand recognition and cell
adhesion . . . . . . . . . . . . . . . . 1227
B. Fuss and
E. S. Wintergerst and
U. Bartsch and
M. Schachner Molecular characterization and in situ
mRNA localization of the neural
recognition molecule J1-160/180: a
modular structure similar to tenascin 1237
T. Kartasova and
D. R. Roop and
K. A. Holbrook and
S. H. Yuspa Mouse differentiation-specific keratins
1 and 10 require a preexisting keratin
scaffold to form a filament network . . 1251
N. I. Perrone-Bizzozero and
V. V. Cansino and
D. T. Kohn Posttranscriptional regulation of GAP-43
gene expression in PC12 cells through
protein kinase C-dependent stabilization
of the mRNA . . . . . . . . . . . . . . 1263
E. Kuivinen and
B. L. Hoffman and
P. A. Hoffman and
C. R. Carlin Structurally related class I and class
II receptor protein tyrosine kinases are
down-regulated by the same E3 protein
coded for by human group C adenoviruses 1271
C. Lu and
R. S. Kerbel Interleukin-6 undergoes transition from
paracrine growth inhibitor to autocrine
stimulator during human melanoma
progression . . . . . . . . . . . . . . 1281
H. Hennekes and
M. Peter and
K. Weber and
E. A. Nigg Phosphorylation on protein kinase C
sites inhibits nuclear import of lamin
B2 . . . . . . . . . . . . . . . . . . . 1293
D. J. Lew and
S. I. Reed Morphogenesis in the yeast cell cycle:
regulation by Cdc28 and cyclins . . . . 1305
J. Jäntti and
E. Kuismanen Effect of caffeine and reduced
temperature (20 degrees C) on the
organization of the pre-Golgi and the
Golgi stack membranes . . . . . . . . . 1321
J. E. Speksnijder and
M. Terasaki and
W. J. Hage and
L. F. Jaffe and
C. Sardet Polarity and reorganization of the
endoplasmic reticulum during
fertilization and ooplasmic segregation
in the ascidian egg . . . . . . . . . . 1337
E. M. Danielsen and
G. H. Hansen and
M. D. Poulsen Apical secretion of apolipoproteins from
enterocytes . . . . . . . . . . . . . . 1347
N. Emans and
J. P. Gorvel and
C. Walter and
V. Gerke and
R. Kellner and
G. Griffiths and
J. Gruenberg Annexin II is a major component of
fusogenic endosomal vesicles . . . . . . 1357
A. J. Huang and
J. E. Manning and
T. M. Bandak and
M. C. Ratau and
K. R. Hanser and
S. C. Silverstein Endothelial cell cytosolic free calcium
regulates neutrophil migration across
monolayers of endothelial cells . . . . 1371
P. A. Conrad and
K. A. Giuliano and
G. Fisher and
K. Collins and
P. T. Matsudaira and
D. L. Taylor Relative distribution of actin, myosin
I, and myosin II during the wound
healing response of fibroblasts . . . . 1381
C. Ruppert and
R. Kroschewski and
M. Bähler Identification, characterization and
cloning of myr 1, a mammalian myosin--I 1393
E. H. Sherr and
M. P. Joyce and
L. A. Greene Mammalian myosin I alpha, I beta, and I
gamma: new widely expressed genes of the
myosin I family . . . . . . . . . . . . 1405
H. Wu and
J. T. Parsons Cortactin, an 80/$ 85$-kilodalton
pp60src substrate, is a filamentous
actin-binding protein enriched in the
cell cortex . . . . . . . . . . . . . . 1417
P. W. Baas and
F. J. Ahmad The transport properties of axonal
microtubules establish their polarity
orientation . . . . . . . . . . . . . . 1427
T. Hasegawa Production of a unique antibody specific
for membrane ruffles and its use to
characterize the behavior of two
distinct types of ruffles . . . . . . . 1439
G. Altankov and
F. Grinnell Depletion of intracellular potassium
disrupts coated pits and reversibly
inhibits cell polarization during
fibroblast spreading . . . . . . . . . . 1449
D. Aeschlimann and
A. Wetterwald and
H. Fleisch and
M. Paulsson Expression of tissue transglutaminase in
skeletal tissues correlates with events
of terminal differentiation of
chondrocytes . . . . . . . . . . . . . . 1461
M. Schörnig and
R. Heumann and
H. Rohrer Synthesis of nerve growth factor mRNA in
cultures of developing mouse whisker
pad, a peripheral target tissue of
sensory trigeminal neurons . . . . . . . 1471
J. Li and
D. C. Koay and
H. Xiao and
A. C. Sartorelli Regulation of the differentiation of
WEHI-3B D+ leukemia cells by granulocyte
colony-stimulating factor receptor . . . 1481
H. Lum and
T. T. Andersen and
A. Siflinger-Birnboim and
C. Tiruppathi and
M. S. Goligorsky and
J. W. Fenton and
A. B. Malik Thrombin receptor peptide inhibits
thrombin-induced increase in endothelial
permeability by receptor desensitization 1491
J. E. Fox and
R. G. Taylor and
M. Taffarel and
J. K. Boyles and
D. E. Goll Evidence that activation of platelet
calpain is induced as a consequence of
binding of adhesive ligand to the
integrin, glycoprotein IIb--IIIa . . . . 1501
I. L. Graham and
J. B. Lefkowith and
D. C. Anderson and
E. J. Brown Immune complex-stimulated neutrophil
LTB4 production is dependent on beta 2
integrins . . . . . . . . . . . . . . . 1509
R. C. Landis and
R. I. Bennett and
N. Hogg A novel LFA-1 activation epitope maps to
the I domain . . . . . . . . . . . . . . 1519
T. Tominaga and
K. Sugie and
M. Hirata and
N. Morii and
J. Fukata and
A. Uchida and
H. Imura and
S. Narumiya Inhibition of PMA-induced,
LFA-1-dependent lymphocyte aggregation
by ADP ribosylation of the small
molecular weight GTP binding protein,
rho . . . . . . . . . . . . . . . . . . 1529
A. Radu and
G. Blobel and
R. W. Wozniak Nup155 is a novel nuclear pore complex
protein that contains neither repetitive
sequence motifs nor reacts with WGA . . 1
L. J. Jung and
T. Kreiner and
R. H. Scheller Expression of mutant ELH prohormones in
AtT-20 cells: the relationship between
prohormone processing and sorting . . . 11
S. L. Milgram and
R. E. Mains and
B. A. Eipper COOH-terminal signals mediate the
trafficking of a peptide processing
enzyme in endocrine cells . . . . . . . 23
S. Ruetz and
A. E. Lindsey and
C. L. Ward and
R. R. Kopito Functional activation of plasma membrane
anion exchangers occurs in a pre-Golgi
compartment . . . . . . . . . . . . . . 37
A. Oprins and
R. Duden and
T. E. Kreis and
H. J. Geuze and
J. W. Slot Beta-COP localizes mainly to the
cis-Golgi side in exocrine pancreas . . 49
S. H. Hansen and
K. Sandvig and
B. van Deurs Clathrin and HA2 adaptors: effects of
potassium depletion, hypertonic medium,
and cytosol acidification . . . . . . . 61
C. Lloyd and
P. Gunning Noncoding regions of the gamma-actin
gene influence the impact of the gene on
myoblast morphology . . . . . . . . . . 73
M. R. Knight and
N. D. Read and
A. K. Campbell and
A. J. Trewavas Imaging calcium dynamics in living
plants using semi-synthetic recombinant
aequorins . . . . . . . . . . . . . . . 83
V. J. LaMorte and
A. T. Harootunian and
A. M. Spiegel and
R. Y. Tsien and
J. R. Feramisco Mediation of growth factor induced DNA
synthesis and calcium mobilization by Gq
and Gi2 . . . . . . . . . . . . . . . . 91
M. Pagano and
R. Pepperkok and
J. Lukas and
V. Baldin and
W. Ansorge and
J. Bartek and
G. Draetta Regulation of the cell cycle by the cdk2
protein kinase in cultured human
fibroblasts . . . . . . . . . . . . . . 101
R. G. Sosnowski and
S. Feldman and
J. R. Feramisco Interference with endogenous ras
function inhibits cellular responses to
wounding . . . . . . . . . . . . . . . . 113
J. Q. Davis and
T. McLaughlin and
V. Bennett Ankyrin-binding proteins related to
nervous system cell adhesion molecules:
candidates to provide transmembrane and
intercellular connections in adult brain 121
Y. Akwa and
N. Sanan\`es and
M. Gouézou and
P. Robel and
E. E. Baulieu and
C. Le Goascogne Astrocytes and neurosteroids: metabolism
of pregnenolone and
dehydroepiandrosterone. Regulation by
cell density . . . . . . . . . . . . . . 135
K. M. Weidner and
M. Sachs and
W. Birchmeier The Met receptor tyrosine kinase
transduces motility, proliferation, and
morphogenic signals of scatter
factor/hepatocyte growth factor in
epithelial cells . . . . . . . . . . . . 145
R. J. Faull and
N. L. Kovach and
J. M. Harlan and
M. H. Ginsberg Affinity modulation of integrin alpha 5
beta 1: regulation of the functional
response by soluble fibronectin . . . . 155
D. I. Leavesley and
M. A. Schwartz and
M. Rosenfeld and
D. A. Cheresh Integrin beta 1- and beta $3$-mediated
endothelial cell migration is triggered
through distinct signaling mechanisms 163
F. Balzac and
A. M. Belkin and
V. E. Koteliansky and
Y. V. Balabanov and
F. Altruda and
L. Silengo and
G. Tarone Expression and functional analysis of a
cytoplasmic domain variant of the beta 1
integrin subunit . . . . . . . . . . . . 171
F. Hogervorst and
L. G. Admiraal and
C. Niessen and
I. Kuikman and
H. Janssen and
H. Daams and
A. Sonnenberg Biochemical characterization and tissue
distribution of the A and B variants of
the integrin alpha 6 subunit . . . . . . 179
E. P. Clarke and
N. Jain and
A. Brickenden and
I. A. Lorimer and
B. D. Sanwal Parallel regulation of procollagen I and
colligin, a collagen-binding protein and
a member of the serine protease
inhibitor family . . . . . . . . . . . . 193
G. M. Bressan and
D. Daga-Gordini and
A. Colombatti and
I. Castellani and
V. Marigo and
D. Volpin Emilin, a component of elastic fibers
preferentially located at the
elastin-microfibrils interface . . . . . 201
E. L. Matunis and
M. J. Matunis and
G. Dreyfuss Association of individual hnRNP proteins
and snRNPs with nascent transcripts . . 219
K. van Zee and
A. Dickmanns and
U. Fischer and
R. Lührmann and
E. Fanning A cytoplasmically anchored nuclear
protein interferes specifically with the
import of nuclear proteins but not U1
snRNA . . . . . . . . . . . . . . . . . 229
J. Bähler and
T. Wyler and
J. Loidl and
J. Kohli Unusual nuclear structures in meiotic
prophase of fission yeast: a cytological
analysis . . . . . . . . . . . . . . . . 241
Y. Wang and
P. A. Loomis and
R. P. Zinkowski and
L. I. Binder A novel tau transcript in cultured human
neuroblastoma cells expressing nuclear
tau . . . . . . . . . . . . . . . . . . 257
T. C. Hobman and
L. Woodward and
M. G. Farquhar The rubella virus E2 and E1 spike
glycoproteins are targeted to the Golgi
complex . . . . . . . . . . . . . . . . 269
C. J. Gottardi and
M. J. Caplan An ion-transporting ATPase encodes
multiple apical localization signals . . 283
B. De Strooper and
L. Umans and
F. Van Leuven and
H. Van Den Berghe Study of the synthesis and secretion of
normal and artificial mutants of murine
amyloid precursor protein (APP):
cleavage of APP occurs in a late
compartment of the default secretion
pathway . . . . . . . . . . . . . . . . 295
P. J. Hollenbeck Products of endocytosis and autophagy
are retrieved from axons by regulated
retrograde organelle transport . . . . . 305
M. R. Jackson and
T. Nilsson and
P. A. Peterson Retrieval of transmembrane proteins to
the endoplasmic reticulum . . . . . . . 317
D. Gundersen and
S. K. Powell and
E. Rodriguez-Boulan Apical polarization of N-CAM in retinal
pigment epithelium is dependent on
contact with the neural retina . . . . . 335
L. Gorza and
S. Schiaffino and
P. Volpe Inositol 1,4,5-trisphosphate receptor in
heart: evidence for its concentration in
Purkinje myocytes of the conduction
system . . . . . . . . . . . . . . . . . 345
D. Choquet and
M. Partiseti and
S. Amigorena and
C. Bonnerot and
W. H. Fridman and
H. Korn Cross-linking of IgG receptors inhibits
membrane immunoglobulin-stimulated
calcium influx in B lymphocytes . . . . 355
U. W. Goodenough and
B. Shames and
L. Small and
T. Saito and
R. C. Crain and
M. A. Sanders and
J. L. Salisbury The role of calcium in the
\bionameChlamydomonas reinhardtii mating
reaction . . . . . . . . . . . . . . . . 365
S. Okabe and
H. Miyasaka and
N. Hirokawa Dynamics of the neuronal intermediate
filaments . . . . . . . . . . . . . . . 375
O. Ohara and
Y. Gahara and
T. Miyake and
H. Teraoka and
T. Kitamura Neurofilament deficiency in quail caused
by nonsense mutation in neurofilament--L
gene . . . . . . . . . . . . . . . . . . 387
L. K. Needham and
R. L. Schnaar Carbohydrate recognition in the
peripheral nervous system: a
calcium-dependent membrane binding site
for HNK-1 reactive glycolipids
potentially involved in Schwann cell
adhesion . . . . . . . . . . . . . . . . 397
Y. Y. Wu and
R. A. Bradshaw Effect of nerve growth factor and
fibroblast growth factor on PC12 cells:
inhibition by orthovanadate . . . . . . 409
A. Muñoz and
C. Wrighton and
B. Seliger and
J. Bernal and
H. Beug Thyroid hormone receptor/c-erbA: control
of commitment and differentiation in the
neuronal/chromaffin progenitor line PC12 423
S. Kojima and
K. Nara and
D. B. Rifkin Requirement for transglutaminase in the
activation of latent transforming growth
factor-beta in bovine endothelial cells 439
A. Levinovitz and
J. Mühlhoff and
S. Isenmann and
D. Vestweber Identification of a glycoprotein ligand
for E-selectin on mouse myeloid cells 449
B. E. Vogel and
S. J. Lee and
A. Hildebrand and
W. Craig and
M. D. Pierschbacher and
F. Wong-Staal and
E. Ruoslahti A novel integrin specificity exemplified
by binding of the alpha v beta 5
integrin to the basic domain of the HIV
Tat protein and vitronectin . . . . . . 461
J. M. Sipes and
N. Guo and
E. N\`egre and
T. Vogel and
H. C. Krutzsch and
D. D. Roberts Inhibition of fibronectin binding and
fibronectin-mediated cell adhesion to
collagen by a peptide from the second
type I repeat of thrombospondin . . . . 469
R. S. Buxton and
P. Cowin and
W. W. Franke and
D. R. Garrod and
K. J. Green and
I. A. King and
P. J. Koch and
A. I. Magee and
D. A. Rees and
J. R. Stanley Nomenclature of the desmosomal cadherins 481
S. Citi The molecular organization of tight
junctions . . . . . . . . . . . . . . . 485
M. Itoh and
A. Nagafuchi and
S. Yonemura and
T. Kitani-Yasuda and
S. Tsukita and
S. Tsukita The 220-kD protein colocalizing with
cadherins in non-epithelial cells is
identical to ZO-1, a tight
junction-associated protein in
epithelial cells: cDNA cloning and
immunoelectron microscopy . . . . . . . 491
P. Y. Goh and
J. V. Kilmartin NDC10: a gene involved in chromosome
segregation in \bionameSaccharomyces
cerevisiae . . . . . . . . . . . . . . . 503
W. Jiang and
J. Lechner and
J. Carbon Isolation and characterization of a gene
(CBF2) specifying a protein component of
the budding yeast kinetochore . . . . . 513
B. Sodeik and
R. W. Doms and
M. Ericsson and
G. Hiller and
C. E. Machamer and
W. van 't Hof and
G. van Meer and
B. Moss and
G. Griffiths Assembly of vaccinia virus: role of the
intermediate compartment between the
endoplasmic reticulum and the Golgi
stacks . . . . . . . . . . . . . . . . . 521
F. W. Tse and
A. Iwata and
W. Almers Membrane flux through the pore formed by
a fusogenic viral envelope protein
during cell fusion . . . . . . . . . . . 543
A. Lütcke and
S. Jansson and
R. G. Parton and
P. Chavrier and
A. Valencia and
L. A. Huber and
E. Lehtonen and
M. Zerial Rab17, a novel small GTPase, is specific
for epithelial cells and is induced
during cell polarization . . . . . . . . 553
W. M. Bement and
P. Forscher and
M. S. Mooseker A novel cytoskeletal structure involved
in purse string wound closure and cell
polarity maintenance . . . . . . . . . . 565
R. W. Mercer and
D. Biemesderfer and
D. P. Bliss and
J. H. Collins and
B. Forbush Molecular cloning and immunological
characterization of the gamma
polypeptide, a small protein associated
with the Na,K--ATPase . . . . . . . . . 579
J. O. Vigoreaux and
J. D. Saide and
K. Valgeirsdottir and
M. L. Pardue Flightin, a novel myofibrillar protein
of \bionameDrosophila stretch-activated
muscles . . . . . . . . . . . . . . . . 587
W. Witke and
A. Hofmann and
B. Köppel and
M. Schleicher and
A. A. Noegel The Ca(2+)-binding domains in non-muscle
type alpha-actinin: biochemical and
genetic analysis . . . . . . . . . . . . 599
G. Wiche and
D. Gromov and
A. Donovan and
M. J. Castañón and
E. Fuchs Expression of plectin mutant cDNA in
cultured cells indicates a role of
COOH-terminal domain in intermediate
filament association . . . . . . . . . . 607
K. P. Lu and
S. A. Osmani and
A. H. Osmani and
A. R. Means Essential roles for calcium and
calmodulin in G2/M progression in
\bionameAspergillus nidulans . . . . . . 621
R. Kopan and
H. Weintraub Mouse notch: expression in hair
follicles correlates with cell fate
determination . . . . . . . . . . . . . 631
C. L. Williams and
V. Y. Hayes and
A. M. Hummel and
J. E. Tarara and
T. J. Halsey Regulation of E-cadherin-mediated
adhesion by muscarinic acetylcholine
receptors in small cell lung carcinoma 643
M. Hahne and
U. Jäger and
S. Isenmann and
R. Hallmann and
D. Vestweber Five tumor necrosis factor-inducible
cell adhesion mechanisms on the surface
of mouse endothelioma cells mediate the
binding of leukocytes . . . . . . . . . 655
G. D. Borasio and
A. Markus and
A. Wittinghofer and
Y. A. Barde and
R. Heumann Involvement of ras p21 in
neurotrophin-induced response of
sensory, but not sympathetic neurons . . 665
H. P. McNamee and
D. E. Ingber and
M. A. Schwartz Adhesion to fibronectin stimulates
inositol lipid synthesis and enhances
PDGF-induced inositol lipid breakdown 673
J. I. Jones and
A. Gockerman and
W. H. Busby and
C. Camacho-Hubner and
D. R. Clemmons Extracellular matrix contains
insulin-like growth factor binding
protein-5: potentiation of the effects
of IGF--I . . . . . . . . . . . . . . . 679
D. G. Tang and
Y. Q. Chen and
C. A. Diglio and
K. V. Honn Protein kinase C-dependent effects of
12(S)-HETE on endothelial cell
vitronectin receptor and fibronectin
receptor . . . . . . . . . . . . . . . . 689
P. Bellosta and
D. Talarico and
D. Rogers and
C. Basilico Cleavage of K--FGF produces a truncated
molecule with increased biological
activity and receptor binding affinity 705
A. G. Matera and
D. C. Ward Nucleoplasmic organization of small
nuclear ribonucleoproteins in cultured
human cells . . . . . . . . . . . . . . 715
Z. Zachar and
J. Kramer and
I. P. Mims and
P. M. Bingham Evidence for channeled diffusion of
pre-mRNAs during nuclear RNA transport
in metazoans . . . . . . . . . . . . . . 729
S. High and
S. S. Andersen and
D. Görlich and
E. Hartmann and
S. Prehn and
T. A. Rapoport and
B. Dobberstein Sec61p is adjacent to nascent type I and
type II signal-anchor proteins during
their membrane insertion . . . . . . . . 743
J. B. Helms and
D. J. Palmer and
J. E. Rothman Two distinct populations of ARF bound to
Golgi membranes . . . . . . . . . . . . 751
D. McCollum and
E. Monosov and
S. Subramani The pas8 mutant of Pichia pastoris
exhibits the peroxisomal protein import
deficiencies of Zellweger syndrome
cells--the PAS8 protein binds to the
COOH-terminal tripeptide peroxisomal
targeting signal, and is a member of the
TPR protein family . . . . . . . . . . . 761
L. A. Jaffe and
C. J. Gallo and
R. H. Lee and
Y. K. Ho and
T. L. Jones Oocyte maturation in starfish is
mediated by the beta gamma-subunit
complex of a G-protein . . . . . . . . . 775
D. P. Jasmer \bionameTrichinella spiralis infected
skeletal muscle cells arrest in G2/M and
cease muscle gene expression . . . . . . 785
M. Cho and
S. G. Webster and
H. M. Blau Evidence for myoblast-extrinsic
regulation of slow myosin heavy chain
expression during muscle fiber formation
in embryonic development . . . . . . . . 795
G. Schevzov and
C. Lloyd and
D. Hailstones and
P. Gunning Differential regulation of tropomyosin
isoform organization and gene expression
in response to altered actin gene
expression . . . . . . . . . . . . . . . 811
J. W. Raff and
D. R. Kellogg and
B. M. Alberts Drosophila gamma-tubulin is part of a
complex containing two previously
identified centrosomal MAPs . . . . . . 823
K. Weber and
N. Geisler and
U. Plessmann and
A. Bremerich and
K. F. Lechtreck and
M. Melkonian SF-assemblin, the structural protein of
the $2$-nm filaments from striated
microtubule associated fibers of algal
flagellar roots, forms a segmented
coiled coil . . . . . . . . . . . . . . 837
F. Gounari and
A. Merdes and
R. Quinlan and
J. Hess and
P. G. FitzGerald and
C. A. Ouzounis and
S. D. Georgatos Bovine filensin possesses primary and
secondary structure similarity to
intermediate filament proteins . . . . . 847
M. J. Fietz and
C. J. McLaughlan and
M. T. Campbell and
G. E. Rogers Analysis of the sheep trichohyalin gene:
potential structural and calcium-binding
roles of trichohyalin in the hair
follicle . . . . . . . . . . . . . . . . 855
J. Fan and
S. G. Mansfield and
T. Redmond and
P. R. Gordon-Weeks and
J. A. Raper The organization of F-actin and
microtubules in growth cones exposed to
a brain-derived collapsing factor . . . 867
H. Ninomiya and
J. M. Roch and
M. P. Sundsmo and
D. A. Otero and
T. Saitoh Amino acid sequence RERMS represents the
active domain of amyloid beta/A4 protein
precursor that promotes fibroblast
growth . . . . . . . . . . . . . . . . . 879
G. Griffo and
C. Hamon-Benais and
P. O. Angrand and
M. Fox and
L. West and
O. Lecoq and
S. Povey and
D. Cassio and
M. Weiss HNF4 and HNF1 as well as a panel of
hepatic functions are extinguished and
reexpressed in parallel in chromosomally
reduced rat hepatoma-human fibroblast
hybrids . . . . . . . . . . . . . . . . 887
Y. Ishizaki and
J. T. Voyvodic and
J. F. Burne and
M. C. Raff Control of lens epithelial cell survival 899
M. Samuels and
R. M. Ezzell and
T. J. Cardozo and
D. R. Critchley and
J. L. Coll and
E. D. Adamson Expression of chicken vinculin
complements the adhesion-defective
phenotype of a mutant mouse F9 embryonal
carcinoma cell . . . . . . . . . . . . . 909
F. D. Yelian and
N. A. Edgeworth and
L. J. Dong and
A. E. Chung and
D. R. Armant Recombinant entactin promotes mouse
primary trophoblast cell adhesion and
migration through the Arg--Gly--Asp
(RGD) recognition sequence . . . . . . . 923
J. R. Gamble and
L. J. Matthias and
G. Meyer and
P. Kaur and
G. Russ and
R. Faull and
M. C. Berndt and
M. A. Vadas Regulation of in vitro capillary tube
formation by anti-integrin antibodies 931
J. D. Loike and
R. Silverstein and
L. Cao and
L. Solomon and
J. Weitz and
E. Haber and
G. R. Matsueda and
M. S. Bernatowicz and
S. C. Silverstein Activated platelets form protected zones
of adhesion on fibrinogen and
fibronectin-coated surfaces . . . . . . 945
H. Funabiki and
I. Hagan and
S. Uzawa and
M. Yanagida Cell cycle-dependent specific
positioning and clustering of
centromeres and telomeres in fission
yeast . . . . . . . . . . . . . . . . . 961
H. Lütcke and
S. Prehn and
A. J. Ashford and
M. Remus and
R. Frank and
B. Dobberstein Assembly of the 68- and 72-kD proteins
of signal recognition particle with 7S
RNA . . . . . . . . . . . . . . . . . . 977
J. Vidugiriene and
A. K. Menon Early lipid intermediates in
glycosyl-phosphatidylinositol anchor
assembly are synthesized in the ER and
located in the cytoplasmic leaflet of
the ER membrane bilayer . . . . . . . . 987
J. Klumperman and
A. Hille and
T. Veenendaal and
V. Oorschot and
W. Stoorvogel and
K. von Figura and
H. J. Geuze Differences in the endosomal
distributions of the two mannose
$6$-phosphate receptors . . . . . . . . 997
E. L. Racoosin and
J. A. Swanson Macropinosome maturation and fusion with
tubular lysosomes in macrophages . . . . 1011
B. R. Miller and
M. G. Cumsky Intramitochondrial sorting of the
precursor to yeast cytochrome c oxidase
subunit Va . . . . . . . . . . . . . . . 1021
C. Zurzolo and
M. P. Lisanti and
I. W. Caras and
L. Nitsch and
E. Rodriguez-Boulan Glycosylphosphatidylinositol-anchored
proteins are preferentially targeted to
the basolateral surface in Fischer rat
thyroid epithelial cells . . . . . . . . 1031
A. Villa and
P. Podini and
M. C. Panzeri and
H. D. Söling and
P. Volpe and
J. Meldolesi The endoplasmic-sarcoplasmic reticulum
of smooth muscle: immunocytochemistry of
vas deferens fibers reveals specialized
subcompartments differently equipped for
the control of Ca$^{2+}$ homeostasis . . 1041
T. Funatsu and
E. Kono and
S. Tsukita Time-resolved electron microscopic
analysis of the behavior of myosin heads
on actin filaments after photolysis of
caged ATP . . . . . . . . . . . . . . . 1053
C. Shapland and
J. J. Hsuan and
N. F. Totty and
D. Lawson Purification and properties of
transgelin: a transformation and shape
change sensitive actin-gelling protein 1065
N. Hosoya and
H. Hosoya and
S. Yamashiro and
H. Mohri and
F. Matsumura Localization of caldesmon and its
dephosphorylation during cell division 1075
S. Ray and
E. Meyhöfer and
R. A. Milligan and
J. Howard Kinesin follows the microtubule's
protofilament axis . . . . . . . . . . . 1083
A. H. Gough and
D. L. Taylor Fluorescence anisotropy imaging
microscopy maps calmodulin binding
during cellular contraction and
locomotion . . . . . . . . . . . . . . . 1095
C. Missero and
C. Serra and
K. Stenn and
G. P. Dotto Skin-specific expression of a truncated
E1a oncoprotein binding to p105-Rb leads
to abnormal hair follicle maturation
without increased epidermal
proliferation . . . . . . . . . . . . . 1109
J. K. Bubien and
L. J. Zhou and
P. D. Bell and
R. A. Frizzell and
T. F. Tedder Transfection of the CD20 cell surface
molecule into ectopic cell types
generates a Ca$^{2+}$ conductance found
constitutively in B lymphocytes . . . . 1121
H. Oda and
T. Uemura and
K. Shiomi and
A. Nagafuchi and
S. Tsukita and
M. Takeichi Identification of a \bionameDrosophila
homologue of alpha-catenin and its
association with the armadillo protein 1133
E. A. Wayner and
S. G. Gil and
G. F. Murphy and
M. S. Wilke and
W. G. Carter Epiligrin, a component of epithelial
basement membranes, is an adhesive
ligand for alpha 3 beta 1 positive T
lymphocytes . . . . . . . . . . . . . . 1141
J. L. Kelly and
A. Sánchez and
G. S. Brown and
C. N. Chesterman and
M. J. Sleigh Accumulation of PDGF B and cell-binding
forms of PDGF A in the extracellular
matrix . . . . . . . . . . . . . . . . . 1153
B. J. Dzamba and
H. Wu and
R. Jaenisch and
D. M. Peters Fibronectin binding site in type I
collagen regulates fibronectin fibril
formation . . . . . . . . . . . . . . . 1165
P. Lu Valle and
M. Iwamoto and
P. Fanning and
M. Pacifici and
B. R. Olsen Multiple negative elements in a gene
that codes for an extracellular matrix
protein, collagen X, restrict expression
to hypertrophic chondrocytes . . . . . . 1173
T. F. Linsenmayer and
E. Gibney and
F. Igoe and
M. K. Gordon and
J. M. Fitch and
L. I. Fessler and
D. E. Birk Type V collagen: molecular structure and
fibrillar organization of the chicken
alpha 1(V) NH2-terminal domain, a
putative regulator of corneal
fibrillogenesis . . . . . . . . . . . . 1181
H. C. Joshi and
P. W. Baas A new perspective on microtubules and
axon growth . . . . . . . . . . . . . . 1191
S. F. Nothwehr and
C. J. Roberts and
T. H. Stevens Membrane protein retention in the yeast
Golgi apparatus: dipeptidyl
aminopeptidase A is retained by a
cytoplasmic signal containing aromatic
residues . . . . . . . . . . . . . . . . 1197
S. L. Wolin and
P. Walter Discrete nascent chain lengths are
required for the insertion of
presecretory proteins into microsomal
membranes . . . . . . . . . . . . . . . 1211
R. C. Piper and
C. Tai and
P. Kulesza and
S. Pang and
D. Warnock and
J. Baenziger and
J. W. Slot and
H. J. Geuze and
C. Puri and
D. E. James GLUT-4 NH2 terminus contains a
phenylalanine-based targeting motif that
regulates intracellular sequestration 1221
A. Mayer and
R. Lill and
W. Neupert Translocation and insertion of precursor
proteins into isolated outer membranes
of mitochondria . . . . . . . . . . . . 1233
T. A. Vida and
G. Huyer and
S. D. Emr Yeast vacuolar proenzymes are sorted in
the late Golgi complex and transported
to the vacuole via a prevacuolar
endosome-like compartment . . . . . . . 1245
S. Mayor and
J. F. Presley and
F. R. Maxfield Sorting of membrane components from
endosomes and subsequent recycling to
the cell surface occurs by a bulk flow
process . . . . . . . . . . . . . . . . 1257
G. Lüers and
T. Hashimoto and
H. D. Fahimi and
A. Völkl Biogenesis of peroxisomes: isolation and
characterization of two distinct
peroxisomal populations from normal and
regenerating rat liver . . . . . . . . . 1271
B. Johansson and
M. P. Wymann and
K. Holmgren-Peterson and
K. E. Magnusson N-formyl peptide receptors in human
neutrophils display distinct membrane
distribution and lateral mobility when
labeled with agonist and antagonist . . 1281
L. M. Mendoza and
D. Nishioka and
V. D. Vacquier A GPI-anchored sea urchin sperm membrane
protein containing EGF domains is
related to human uromodulin . . . . . . 1291
S. J. Neame and
C. M. Isacke The cytoplasmic tail of CD44 is required
for basolateral localization in
epithelial MDCK cells but does not
mediate association with the
detergent-insoluble cytoskeleton of
fibroblasts . . . . . . . . . . . . . . 1299
J. Heuser and
Q. Zhu and
M. Clarke Proton pumps populate the contractile
vacuoles of \bionameDictyostelium
amoebae . . . . . . . . . . . . . . . . 1311
M. E. Bertagnolli and
M. C. Beckerle Evidence for the selective association
of a subpopulation of GPIIb--IIIa with
the actin cytoskeletons of
thrombin-activated platelets . . . . . . 1329
S. N. Hird and
J. G. White Cortical and cytoplasmic flow polarity
in early embryonic cells of
\bionameCaenorhabditis elegans . . . . . 1343
S. Leibler and
D. A. Huse Porters versus rowers: a unified
stochastic model of motor proteins . . . 1357
C. H. Lin and
P. Forscher Cytoskeletal remodeling during growth
cone-target interactions . . . . . . . . 1369
N. N. Desai and
R. O. Carlson and
M. E. Mattie and
A. Olivera and
N. E. Buckley and
T. Seki and
G. Brooker and
S. Spiegel Signaling pathways for
sphingosylphosphorylcholine-mediated
mitogenesis in Swiss 3T3 fibroblasts . . 1385
R. D. McKinnon and
G. Piras and
J. A. Ida and
M. Dubois-Dalcq A role for TGF-beta in oligodendrocyte
differentiation . . . . . . . . . . . . 1397
R. Horstkorte and
M. Schachner and
J. P. Magyar and
T. Vorherr and
B. Schmitz The fourth immunoglobulin-like domain of
NCAM contains a carbohydrate recognition
domain for oligomannosidic glycans
implicated in association with L1 and
neurite outgrowth . . . . . . . . . . . 1409
R. C. Johnson and
D. Zhu and
H. G. Augustin-Voss and
B. U. Pauli Lung endothelial dipeptidyl peptidase IV
is an adhesion molecule for
lung-metastatic rat breast and prostate
carcinoma cells . . . . . . . . . . . . 1423
P. M. Tremble and
T. F. Lane and
E. H. Sage and
Z. Werb SPARC, a secreted protein associated
with morphogenesis and tissue
remodeling, induces expression of
metalloproteinases in fibroblasts
through a novel extracellular
matrix-dependent pathway . . . . . . . . 1433
C. W. Akey and
M. Radermacher Architecture of the \bionameXenopus
nuclear pore complex revealed by
three-dimensional cryo-electron
microscopy . . . . . . . . . . . . . . . 1
W. J. Deery and
J. P. Heath Phagocytosis induced by thyrotropin in
cultured thyroid cells is associated
with myosin light chain
dephosphorylation and stress fiber
disruption . . . . . . . . . . . . . . . 21
A. Velasco and
L. Hendricks and
K. W. Moremen and
D. R. Tulsiani and
O. Touster and
M. G. Farquhar Cell type-dependent variations in the
subcellular distribution of
alpha-mannosidase I and II . . . . . . . 39
N. G. Davis and
J. L. Horecka and
G. F. Sprague Cis- and trans-acting functions required
for endocytosis of the yeast pheromone
receptors . . . . . . . . . . . . . . . 53
T. Wileman and
L. P. Kane and
J. Young and
G. R. Carson and
C. Terhorst Associations between subunit ectodomains
promote T cell antigen receptor assembly
and protect against degradation in the
ER . . . . . . . . . . . . . . . . . . . 67
E. A. Whitters and
A. E. Cleves and
T. P. McGee and
H. B. Skinner and
V. A. Bankaitis SAC1p is an integral membrane protein
that influences the cellular requirement
for phospholipid transfer protein
function and inositol in yeast . . . . . 79
M. W. Bosenberg and
A. Pandiella and
J. Massagué Activated release of membrane-anchored
TGF-alpha in the absence of cytosol . . 95
A. Desmouli\`ere and
A. Geinoz and
F. Gabbiani and
G. Gabbiani Transforming growth factor-beta 1
induces alpha-smooth muscle actin
expression in granulation tissue
myofibroblasts and in quiescent and
growing cultured fibroblasts . . . . . . 103
J. Baker and
W. E. Theurkauf and
G. Schubiger Dynamic changes in microtubule
configuration correlate with nuclear
migration in the preblastoderm
\bionameDrosophila embryo . . . . . . . 113
R. K. Miller and
S. Khuon and
R. D. Goldman Dynamics of keratin assembly: exogenous
type I keratin rapidly associates with
type II keratin in vivo . . . . . . . . 123
T. Saito and
L. Small and
U. W. Goodenough Activation of adenylyl cyclase in
\bionameChlamydomonas reinhardtii by
adhesion and by heat . . . . . . . . . . 137
R. Cooper and
A. R. de Jesus and
G. A. Cross Deletion of an immunodominant
Trypanosoma cruzi surface glycoprotein
disrupts flagellum-cell adhesion . . . . 149
C. Tomasetto and
M. J. Neveu and
J. Daley and
P. K. Horan and
R. Sager Specificity of gap junction
communication among human mammary cells
and connexin transfectants in culture 157
C. M. Yoshihara and
Z. W. Hall Increased expression of the 43-kD
protein disrupts acetylcholine receptor
clustering in myotubes . . . . . . . . . 169
P. Doherty and
A. Singh and
G. Rimon and
S. R. Bolsover and
F. S. Walsh Thy-1 antibody-triggered neurite
outgrowth requires an influx of calcium
into neurons via N- and L-type calcium
channels . . . . . . . . . . . . . . . . 181
O. Lefebvre and
C. Wolf and
M. Kédinger and
M. P. Chenard and
C. Tomasetto and
P. Chambon and
M. C. Rio The mouse one P-domain (pS2) and two
P-domain (mSP) genes exhibit distinct
patterns of expression . . . . . . . . . 191
E. Stöcklin and
F. Botteri and
B. Groner An activated allele of the c-erbB-2
oncogene impairs kidney and lung
function and causes early death of
transgenic mice . . . . . . . . . . . . 199
J. S. Bauer and
J. Varner and
C. Schreiner and
L. Kornberg and
R. Nicholas and
R. L. Juliano Functional role of the cytoplasmic
domain of the integrin alpha 5 subunit 209
J. Ylänne and
Y. Chen and
T. E. O'Toole and
J. C. Loftus and
Y. Takada and
M. H. Ginsberg Distinct functions of integrin alpha and
beta subunit cytoplasmic domains in cell
spreading and formation of focal
adhesions . . . . . . . . . . . . . . . 223
Z. Zhang and
A. O. Morla and
K. Vuori and
J. S. Bauer and
R. L. Juliano and
E. Ruoslahti The alpha v beta 1 integrin functions as
a fibronectin receptor but does not
support fibronectin matrix assembly and
cell migration on fibronectin . . . . . 235
C. Nathan and
Q. W. Xie and
L. Halbwachs-Mecarelli and
W. W. Jin Albumin inhibits neutrophil spreading
and hydrogen peroxide release by
blocking the shedding of CD43
(sialophorin, leukosialin) . . . . . . . 243
R. J. Peach and
D. Hollenbaugh and
I. Stamenkovic and
A. Aruffo Identification of hyaluronic acid
binding sites in the extracellular
domain of CD44 . . . . . . . . . . . . . 257
J. Bristow and
M. K. Tee and
S. E. Gitelman and
S. H. Mellon and
W. L. Miller Tenascin-X: a novel extracellular matrix
protein encoded by the human XB gene
overlapping P450c21B . . . . . . . . . . 265
D. G. Wansink and
W. Schul and
I. van der Kraan and
B. van Steensel and
R. van Driel and
L. de Jong Fluorescent labeling of nascent RNA
reveals transcription by RNA polymerase
II in domains scattered throughout the
nucleus . . . . . . . . . . . . . . . . 283
N. Chaudhary and
J. C. Courvalin Stepwise reassembly of the nuclear
envelope at the end of mitosis . . . . . 295
C. Abeijon and
K. Yanagisawa and
E. C. Mandon and
A. Häusler and
K. Moremen and
C. B. Hirschberg and
P. W. Robbins Guanosine diphosphatase is required for
protein and sphingolipid glycosylation
in the Golgi lumen of
\bionameSaccharomyces cerevisiae . . . . 307
G. Müller and
W. Bandlow Glucose induces lipolytic cleavage of a
glycolipidic plasma membrane anchor in
yeast . . . . . . . . . . . . . . . . . 325
A. P. Gilmore and
C. Wood and
V. Ohanian and
P. Jackson and
B. Patel and
D. J. Rees and
R. O. Hynes and
D. R. Critchley The cytoskeletal protein talin contains
at least two distinct vinculin binding
domains . . . . . . . . . . . . . . . . 337
W. Yu and
V. E. Centonze and
F. J. Ahmad and
P. W. Baas Microtubule nucleation and release from
the neuronal centrosome . . . . . . . . 349
J. C. Waters and
R. W. Cole and
C. L. Rieder The force-producing mechanism for
centrosome separation during spindle
formation in vertebrates is intrinsic to
each aster . . . . . . . . . . . . . . . 361
E. G. Flescher and
K. Madden and
M. Snyder Components required for cytokinesis are
important for bud site selection in
yeast . . . . . . . . . . . . . . . . . 373
P. Snow and
R. Nuccitelli Calcium buffer injections delay cleavage
in \bionameXenopus laevis blastomeres 387
M. B. McCormick and
P. Kouklis and
A. Syder and
E. Fuchs The roles of the rod end and the tail in
vimentin IF assembly and IF network
formation . . . . . . . . . . . . . . . 395
S. Kárpáti and
M. Amagai and
R. Prussick and
K. Cehrs and
J. R. Stanley Pemphigus vulgaris antigen, a desmoglein
type of cadherin, is localized within
keratinocyte desmosomes . . . . . . . . 409
H. Smola and
G. Thiekötter and
N. E. Fusenig Mutual induction of growth factor gene
expression by epidermal-dermal cell
interaction . . . . . . . . . . . . . . 417
M. Salmi and
K. Grön-Virta and
P. Sointu and
R. Grenman and
H. Kalimo and
S. Jalkanen Regulated expression of exon v6
containing isoforms of CD44 in man:
downregulation during malignant
transformation of tumors of
squamocellular origin . . . . . . . . . 431
D. Lindholm and
E. Castrén and
P. Tsoulfas and
R. Kolbeck and
M. da P. Berzaghi and
A. Leingärtner and
C. P. Heisenberg and
L. Tessarollo and
L. F. Parada and
H. Thoenen and
L. Tesarollo Neurotrophin-3 induced by
tri-iodothyronine in cerebellar granule
cells promotes Purkinje cell
differentiation . . . . . . . . . . . . 443
M. T. Filbin and
G. I. Tennekoon Homophilic adhesion of the myelin P0
protein requires glycosylation of both
molecules in the homophilic pair . . . . 451
E. K. Han and
T. M. Guadagno and
S. L. Dalton and
R. K. Assoian A cell cycle and mutational analysis of
anchorage-independent growth: cell
adhesion and TGF-beta 1 control G1/S
transit specifically . . . . . . . . . . 461
M. M. Huang and
L. Lipfert and
M. Cunningham and
J. S. Brugge and
M. H. Ginsberg and
S. J. Shattil Adhesive ligand binding to integrin
alpha IIb beta 3 stimulates tyrosine
phosphorylation of novel protein
substrates before phosphorylation of
pp125FAK . . . . . . . . . . . . . . . . 473
S. J. Samuelsson and
P. W. Luther and
D. W. Pumplin and
R. J. Bloch Structures linking microfilament bundles
to the membrane at focal contacts . . . 485
S. S. Tolsma and
O. V. Volpert and
D. J. Good and
W. A. Frazier and
P. J. Polverini and
N. Bouck Peptides derived from two separate
domains of the matrix protein
thrombospondin-1 have anti-angiogenic
activity . . . . . . . . . . . . . . . . 497
E. Hallberg and
R. W. Wozniak and
G. Blobel An integral membrane protein of the pore
membrane domain of the nuclear envelope
contains a nucleoporin-like region . . . 513
A. Batistatou and
L. A. Greene Internucleosomal DNA cleavage and
neuronal cell survival/death . . . . . . 523
E. Souter and
M. Pypaert and
G. Warren The Golgi stack reassembles during
telophase before arrival of proteins
transported from the endoplasmic
reticulum . . . . . . . . . . . . . . . 533
C. Schulze-Garg and
C. Böker and
S. K. Nadimpalli and
K. von Figura and
A. Hille-Rehfeld Tail-specific antibodies that block
return of 46,000 M(r) mannose
$6$-phosphate receptor to the
trans-Golgi network . . . . . . . . . . 541
A. M. van der Bliek and
T. E. Redelmeier and
H. Damke and
E. J. Tisdale and
E. M. Meyerowitz and
S. L. Schmid Mutations in human dynamin block an
intermediate stage in coated vesicle
formation . . . . . . . . . . . . . . . 553
J. S. Herskovits and
C. C. Burgess and
R. A. Obar and
R. B. Vallee Effects of mutant rat dynamin on
endocytosis . . . . . . . . . . . . . . 565
A. W. Hudson and
D. C. Fingar and
G. A. Seidner and
G. Griffiths and
B. Burke and
M. J. Birnbaum Targeting of the ``insulin-responsive''
glucose transporter (GLUT4) to the
regulated secretory pathway in PC12
cells . . . . . . . . . . . . . . . . . 579
M. D. Sjaastad and
K. S. Zettl and
G. Parry and
G. L. Firestone and
T. E. Machen Hormonal regulation of the polarized
function and distribution of Na/H
exchange and Na/HCO3 cotransport in
cultured mammary epithelial cells . . . 589
J. A. Porter and
C. Montell Distinct roles of the \bionameDrosophila
ninaC kinase and myosin domains revealed
by systematic mutagenesis . . . . . . . 601
J. S. Wolenski and
S. M. Hayden and
P. Forscher and
M. S. Mooseker Calcium-calmodulin and regulation of
brush border myosin--I MgATPase and
mechanochemistry . . . . . . . . . . . . 613
T. E. Morgan and
R. O. Lockerbie and
L. S. Minamide and
M. D. Browning and
J. R. Bamburg Isolation and characterization of a
regulated form of actin depolymerizing
factor . . . . . . . . . . . . . . . . . 623
D. A. Holtzman and
S. Yang and
D. G. Drubin Synthetic-lethal interactions identify
two novel genes, SLA1 and SLA2, that
control membrane cytoskeleton assembly
in \bionameSaccharomyces cerevisiae . . 635
J. R. Fabian and
D. K. Morrison and
I. O. Daar Requirement for Raf and MAP kinase
function during the meiotic maturation
of \bionameXenopus oocytes . . . . . . . 645
H. Sakakibara and
S. Takada and
S. M. King and
G. B. Witman and
R. Kamiya A \bionameChlamydomonas outer arm dynein
mutant with a truncated beta heavy chain 653
Y. C. Lin and
F. Grinnell Decreased level of PDGF-stimulated
receptor autophosphorylation by
fibroblasts in mechanically relaxed
collagen matrices . . . . . . . . . . . 663
M. S. Pepper and
A. P. Sappino and
R. Stöcklin and
R. Montesano and
L. Orci and
J. D. Vassalli Upregulation of urokinase receptor
expression on migrating endothelial
cells . . . . . . . . . . . . . . . . . 673
A. E. Grigoriadis and
K. Schellander and
Z. Q. Wang and
E. F. Wagner Osteoblasts are target cells for
transformation in c-fos transgenic mice 685
C. Gentili and
P. Bianco and
M. Neri and
M. Malpeli and
G. Campanile and
P. Castagnola and
R. Cancedda and
F. D. Cancedda Cell proliferation, extracellular matrix
mineralization, and ovotransferrin
transient expression during in vitro
differentiation of chick hypertrophic
chondrocytes into osteoblast-like cells 703
A. Mereau and
L. Grey and
C. Piquet-Pellorce and
J. K. Heath Characterization of a binding protein
for leukemia inhibitory factor localized
in extracellular matrix . . . . . . . . 713
R. Bützow and
D. Fukushima and
D. R. Twardzik and
E. Ruoslahti A 60-kD protein mediates the binding of
transforming growth factor-beta to cell
surface and extracellular matrix
proteoglycans . . . . . . . . . . . . . 721
P. A. DiMilla and
J. A. Stone and
J. A. Quinn and
S. M. Albelda and
D. A. Lauffenburger Maximal migration of human smooth muscle
cells on fibronectin and type IV
collagen occurs at an intermediate
attachment strength . . . . . . . . . . 729
M. Winey and
M. A. Hoyt and
C. Chan and
L. Goetsch and
D. Botstein and
B. Byers NDC1: a nuclear periphery component
required for yeast spindle pole body
duplication . . . . . . . . . . . . . . 743
G. M. Trimbur and
C. J. Walsh Nucleolus-like morphology produced
during the in vitro reassociation of
nucleolar components . . . . . . . . . . 753
R. S. Tuma and
J. A. Stolk and
M. B. Roth Identification and characterization of a
sphere organelle protein . . . . . . . . 767
S. M. Jones and
J. R. Crosby and
J. Salamero and
K. E. Howell A cytosolic complex of p62 and rab6
associates with TGN38/41 and is involved
in budding of exocytic vesicles from the
trans-Golgi network . . . . . . . . . . 775
M. Sargiacomo and
M. Sudol and
Z. Tang and
M. P. Lisanti Signal transducing molecules and
glycosyl-phosphatidylinositol-linked
proteins form a caveolin-rich insoluble
complex in MDCK cells . . . . . . . . . 789
J. M. Ervasti and
K. P. Campbell A role for the dystrophin-glycoprotein
complex as a transmembrane linker
between laminin and actin . . . . . . . 809
M. A. Hill and
P. Gunning Beta and gamma actin mRNAs are
differentially located within myoblasts 825
L. Cramer and
T. J. Mitchison Moving and stationary actin filaments
are involved in spreading of postmitotic
PtK2 cells . . . . . . . . . . . . . . . 833
H. F. Epstein and
D. L. Casey and
I. Ortiz Myosin and paramyosin of
\bionameCaenorhabditis elegans embryos
assemble into nascent structures
distinct from thick filaments and
multi-filament assemblages . . . . . . . 845
R. V. Skibbens and
V. P. Skeen and
E. D. Salmon Directional instability of kinetochore
motility during chromosome congression
and segregation in mitotic newt lung
cells: a push-pull mechanism . . . . . . 859
J. D. Harper and
M. A. Sanders and
J. L. Salisbury Phosphorylation of nuclear and flagellar
basal apparatus proteins during
flagellar regeneration in
\bionameChlamydomonas reinhardtii . . . 877
K. Ohlendieck and
S. T. Dhume and
J. S. Partin and
W. J. Lennarz The sea urchin egg receptor for sperm:
isolation and characterization of the
intact, biologically active receptor . . 887
W. H. Fleming and
E. J. Alpern and
N. Uchida and
K. Ikuta and
G. J. Spangrude and
I. L. Weissman Functional heterogeneity is associated
with the cell cycle status of murine
hematopoietic stem cells . . . . . . . . 897
E. Hölttä and
M. Auvinen and
L. C. Andersson Polyamines are essential for cell
transformation by pp60v-src: delineation
of molecular events relevant for the
transformed phenotype . . . . . . . . . 903
G. D'Arcangelo and
K. Paradiso and
D. Shepherd and
P. Brehm and
S. Halegoua and
G. Mandel Neuronal growth factor regulation of two
different sodium channel types through
distinct signal transduction pathways 915
S. Schultz-Cherry and
J. E. Murphy-Ullrich Thrombospondin causes activation of
latent transforming growth factor-beta
secreted by endothelial cells by a novel
mechanism . . . . . . . . . . . . . . . 923
S. Higashiyama and
J. A. Abraham and
M. Klagsbrun Heparin-binding EGF-like growth factor
stimulation of smooth muscle cell
migration: dependence on interactions
with cell surface heparan sulfate . . . 933
C. Yeaman and
A. C. Rapraeger Post-transcriptional regulation of
syndecan-1 expression by cAMP in
peritoneal macrophages . . . . . . . . . 941
H. Zhou and
A. Fuks and
G. Alcaraz and
T. J. Bolling and
C. P. Stanners Homophilic adhesion between Ig
superfamily carcinoembryonic antigen
molecules involves double reciprocal
bonds . . . . . . . . . . . . . . . . . 951
S. M. Brady-Kalnay and
A. J. Flint and
N. K. Tonks Homophilic binding of PTP mu, a
receptor-type protein tyrosine
phosphatase, can mediate cell--cell
aggregation . . . . . . . . . . . . . . 961
N. Panté and
U. Aebi The nuclear pore complex . . . . . . . . 977
D. Coverley and
C. S. Downes and
P. Romanowski and
R. A. Laskey Reversible effects of nuclear membrane
permeabilization on DNA replication:
evidence for a positive licensing factor 985
J. J. Blow Preventing re-replication of DNA in a
single cell cycle: evidence for a
replication licensing factor . . . . . . 993
J. L. Emtage and
R. E. Jensen MAS6 encodes an essential inner membrane
component of the yeast mitochondrial
protein import pathway . . . . . . . . . 1003
T. S. Vihtelic and
M. Goebl and
S. Milligan and
J. E. O'Tousa and
D. R. Hyde Localization of \bionameDrosophila
retinal degeneration B, a
membrane-associated phosphatidylinositol
transfer protein . . . . . . . . . . . . 1013
K. A. Dryden and
G. Wang and
M. Yeager and
M. L. Nibert and
K. M. Coombs and
D. B. Furlong and
B. N. Fields and
T. S. Baker Early steps in reovirus infection are
associated with dramatic changes in
supramolecular structure and protein
conformation: analysis of virions and
subviral particles by cryoelectron
microscopy and image reconstruction . . 1023
H. Hess and
H. Heid and
W. W. Franke Molecular characterization of mammalian
cylicin, a basic protein of the sperm
head cytoskeleton . . . . . . . . . . . 1043
U. Arumäe and
U. Pirvola and
J. Palgi and
T. R. Kiema and
K. Palm and
M. Moshnyakov and
J. Ylikoski and
M. Saarma Neurotrophins and their receptors in rat
peripheral trigeminal system during
maxillary nerve growth . . . . . . . . . 1053
H. Haegel and
C. Tölg and
M. Hofmann and
R. Ceredig Activated mouse astrocytes and T cells
express similar CD44 variants. Role of
CD44 in astrocyte/T cell binding . . . . 1067
P. Lenormand and
C. Sardet and
G. Pag\`es and
G. L'Allemain and
A. Brunet and
J. Pouysségur Growth factors induce nuclear
translocation of MAP kinases (p42mapk
and p44mapk) but not of their activator
MAP kinase kinase (p45mapkk) in
fibroblasts . . . . . . . . . . . . . . 1079
F. A. Gonzalez and
A. Seth and
D. L. Raden and
D. S. Bowman and
F. S. Fay and
R. J. Davis Serum-induced translocation of
mitogen-activated protein kinase to the
cell surface ruffling membrane and the
nucleus . . . . . . . . . . . . . . . . 1089
A. B. Stoler and
F. Stenback and
A. Balmain The conversion of mouse skin squamous
cell carcinomas to spindle cell
carcinomas is a recessive event . . . . 1103
L. E. French and
A. Chonn and
D. Ducrest and
B. Baumann and
D. Belin and
A. Wohlwend and
J. Z. Kiss and
A. P. Sappino and
J. Tschopp and
J. A. Schifferli Murine clusterin: molecular cloning and
mRNA localization of a gene associated
with epithelial differentiation
processes during embryogenesis . . . . . 1119
A. Arcangeli and
A. Becchetti and
A. Mannini and
G. Mugnai and
P. De Filippi and
G. Tarone and
M. R. Del Bene and
E. Barletta and
E. Wanke and
M. Olivotto Integrin-mediated neurite outgrowth in
neuroblastoma cells depends on the
activation of potassium channels . . . . 1131
F. Peter and
H. Plutner and
H. Zhu and
T. E. Kreis and
W. E. Balch Beta-COP is essential for transport of
protein from the endoplasmic reticulum
to the Golgi in vitro . . . . . . . . . 1155
H. Xu and
D. Shields Prohormone processing in the trans-Golgi
network: endoproteolytic cleavage of
prosomatostatin and formation of nascent
secretory vesicles in permeabilized
cells . . . . . . . . . . . . . . . . . 1169
O. A. Weisz and
A. M. Swift and
C. E. Machamer Oligomerization of a membrane protein
correlates with its retention in the
Golgi complex . . . . . . . . . . . . . 1185
B. Veit and
J. K. Yucel and
V. Malhotra Microtubule independent vesiculation of
Golgi membranes and the reassembly of
vesicles into Golgi stacks . . . . . . . 1197
O. Mundigl and
M. Matteoli and
L. Daniell and
A. Thomas-Reetz and
A. Metcalf and
R. Jahn and
P. De Camilli Synaptic vesicle proteins and early
endosomes in cultured hippocampal
neurons: differential effects of
Brefeldin A in axon and dendrites . . . 1207
D. P. Cerneus and
G. J. Strous and
A. van der Ende Bidirectional transcytosis determines
the steady state distribution of the
transferrin receptor at opposite plasma
membrane domains of BeWo cells . . . . . 1223
J. F. Presley and
S. Mayor and
K. W. Dunn and
L. S. Johnson and
T. E. McGraw and
F. R. Maxfield The End2 mutation in CHO cells slows the
exit of transferrin receptors from the
recycling compartment but bulk membrane
recycling is unaffected . . . . . . . . 1231
J. L. Carpentier and
J. P. Paccaud and
J. Backer and
A. Gilbert and
L. Orci and
C. R. Kahn and
J. Backer Two steps of insulin receptor
internalization depend on different
domains of the beta-subunit . . . . . . 1243
G. W. Kemble and
Y. I. Henis and
J. M. White GPI- and transmembrane-anchored
influenza hemagglutinin differ in
structure and receptor binding activity 1253
J. R. Lepock and
H. E. Frey and
K. P. Ritchie Protein denaturation in intact
hepatocytes and isolated cellular
organelles during heat shock . . . . . . 1267
V. K. Vinson and
S. J. Archer and
E. E. Lattman and
T. D. Pollard and
D. A. Torchia Three-dimensional solution structure of
\bionameAcanthamoeba profilin--I . . . . 1277
J. L. Rodríguez Fernández and
B. Geiger and
D. Salomon and
A. Ben-Ze'ev Suppression of vinculin expression by
antisense transfection confers changes
in cell morphology, motility, and
anchorage-dependent growth of 3T3 cells 1285
E. Evans and
A. Leung and
D. Zhelev Synchrony of cell spreading and
contraction force as phagocytes engulf
large pathogens . . . . . . . . . . . . 1295
R. Melki and
I. E. Vainberg and
R. L. Chow and
N. J. Cowan Chaperonin-mediated folding of
vertebrate actin-related protein and
gamma-tubulin . . . . . . . . . . . . . 1301
G. J. Gorbsky and
W. A. Ricketts Differential expression of a
phosphoepitope at the kinetochores of
moving chromosomes . . . . . . . . . . . 1311
G. Y. Ching and
R. K. Liem Assembly of type IV neuronal
intermediate filaments in nonneuronal
cells in the absence of preexisting
cytoplasmic intermediate filaments . . . 1323
M. K. Lee and
Z. Xu and
P. C. Wong and
D. W. Cleveland Neurofilaments are obligate
heteropolymers in vivo . . . . . . . . . 1337
P. C. Brooks and
J. M. Lin and
D. L. French and
J. P. Quigley Subtractive immunization yields
monoclonal antibodies that specifically
inhibit metastasis . . . . . . . . . . . 1351
D. T. Shih and
J. M. Edelman and
A. F. Horwitz and
G. B. Grunwald and
C. A. Buck Structure\slash function analysis of the
integrin beta 1 subunit by epitope
mapping . . . . . . . . . . . . . . . . 1361
M. Fechheimer and
S. H. Zigmond Focusing on unpolymerized actin . . . . 1
Y. A. Lazebnik and
S. Cole and
C. A. Cooke and
W. G. Nelson and
W. C. Earnshaw Nuclear events of apoptosis in vitro in
cell-free mitotic extracts: a model
system for analysis of the active phase
of apoptosis . . . . . . . . . . . . . . 7
O. H. Weiner and
J. Murphy and
G. Griffiths and
M. Schleicher and
A. A. Noegel The actin-binding protein comitin (p24)
is a component of the Golgi apparatus 23
L. A. Huber and
S. Pimplikar and
R. G. Parton and
H. Virta and
M. Zerial and
K. Simons Rab8, a small GTPase involved in
vesicular traffic between the TGN and
the basolateral plasma membrane . . . . 35
L. A. Huber and
M. J. de Hoop and
P. Dupree and
M. Zerial and
K. Simons and
C. Dotti Protein transport to the dendritic
plasma membrane of cultured neurons is
regulated by rab8p . . . . . . . . . . . 47
M. T. Marquardt and
T. Phalen and
M. Kielian Cholesterol is required in the exit
pathway of Semliki Forest virus . . . . 57
M. S. Robinson Assembly and targeting of adaptin
chimeras in transfected cells . . . . . 67
R. Chakrabarti and
M. Joly and
S. Corvera Redistribution of clathrin-coated
vesicle adaptor complexes during
adipocytic differentiation of 3T3-L1
cells . . . . . . . . . . . . . . . . . 79
S. H. Hansen and
K. Sandvig and
B. van Deurs Molecules internalized by
clathrin-independent endocytosis are
delivered to endosomes containing
transferrin receptors . . . . . . . . . 89
J. N. Glickman and
S. Kornfeld Mannose $6$-phosphate-independent
targeting of lysosomal enzymes in I-cell
disease B lymphoblasts . . . . . . . . . 99
B. D. Gambill and
W. Voos and
P. J. Kang and
B. Miao and
T. Langer and
E. A. Craig and
N. Pfanner A dual role for mitochondrial heat shock
protein 70 in membrane translocation of
preproteins . . . . . . . . . . . . . . 109
W. Voos and
B. D. Gambill and
B. Guiard and
N. Pfanner and
E. A. Craig Presequence and mature part of
preproteins strongly influence the
dependence of mitochondrial protein
import on heat shock protein 70 in the
matrix . . . . . . . . . . . . . . . . . 119
M. P. Czech and
A. Chawla and
C. W. Woon and
J. Buxton and
M. Armoni and
W. Tang and
M. Joly and
S. Corvera Exofacial epitope-tagged glucose
transporter chimeras reveal
COOH-terminal sequences governing
cellular localization . . . . . . . . . 127
K. J. Verhey and
S. F. Hausdorff and
M. J. Birnbaum Identification of the carboxy terminus
as important for the isoform-specific
subcellular targeting of glucose
transporter proteins . . . . . . . . . . 137
J. A. Marrs and
E. W. Napolitano and
C. Murphy-Erdosh and
R. W. Mays and
L. F. Reichardt and
W. J. Nelson Distinguishing roles of the
membrane-cytoskeleton and cadherin
mediated cell--cell adhesion in
generating different Na+,K(+)-ATPase
distributions in polarized epithelia . . 149
E. H. Kislauskis and
Z. Li and
R. H. Singer and
K. L. Taneja Isoform-specific 3'-untranslated
sequences sort alpha-cardiac and
beta-cytoplasmic actin messenger RNAs to
different cytoplasmic compartments . . . 165
L. G. Cao and
D. J. Fishkind and
Y. L. Wang Localization and dynamics of
nonfilamentous actin in cultured cells 173
D. R. Diener and
L. H. Ang and
J. L. Rosenbaum Assembly of flagellar radial spoke
proteins in \bionameChlamydomonas:
identification of the axoneme binding
domain of radial spoke protein 3 . . . . 183
M. M. Kirk and
A. Ransick and
S. E. McRae and
D. L. Kirk The relationship between cell size and
cell fate in Volvox carteri . . . . . . 191
L. L. Wong and
P. N. Adler Tissue polarity genes of
\bionameDrosophila regulate the
subcellular location for prehair
initiation in pupal wing cells . . . . . 209
E. Sonnenberg and
D. Meyer and
K. M. Weidner and
C. Birchmeier Scatter factor/hepatocyte growth factor
and its receptor, the c-met tyrosine
kinase, can mediate a signal exchange
between mesenchyme and epithelia during
mouse development . . . . . . . . . . . 223
L. M. Bolin and
E. M. Shooter Neurons regulate Schwann cell genes by
diffusible molecules . . . . . . . . . . 237
A. Masumoto and
M. E. Hemler Mutation of putative divalent cation
sites in the alpha 4 subunit of the
integrin VLA-4: distinct effects on
adhesion to CS1/fibronectin, VCAM-1, and
invasin . . . . . . . . . . . . . . . . 245
M. H. Sibley and
J. J. Johnson and
C. C. Mello and
J. M. Kramer Genetic identification, sequence, and
alternative splicing of the
\bionameCaenorhabditis elegans alpha
2(IV) collagen gene . . . . . . . . . . 255
J. E. Wilhelm and
R. D. Vale RNA on the move: the mRNA localization
pathway . . . . . . . . . . . . . . . . 269
S. R. Wente and
G. Blobel A temperature-sensitive NUP116 null
mutant forms a nuclear envelope seal
over the yeast nuclear pore complex
thereby blocking nucleocytoplasmic
traffic . . . . . . . . . . . . . . . . 275
M. Wassler and
E. Fries Proteolytic cleavage of haptoglobin
occurs in a subcompartment of the
endoplasmic reticulum: evidence from
membrane fusion in vitro . . . . . . . . 285
M. S. Balda and
L. Gonzalez-Mariscal and
K. Matter and
M. Cereijido and
J. M. Anderson Assembly of the tight junction: the role
of diacylglycerol . . . . . . . . . . . 293
P. R. Deitiker and
H. F. Epstein Thick filament substructures in
\bionameCaenorhabditis elegans: evidence
for two populations of paramyosin . . . 303
P. Vibert and
R. Craig and
W. Lehman Three-dimensional reconstruction of
caldesmon-containing smooth muscle thin
filaments . . . . . . . . . . . . . . . 313
D. G. Simpson and
M. L. Decker and
W. A. Clark and
R. S. Decker Contractile activity and cell--cell
contact regulate myofibrillar
organization in cultured cardiac
myocytes . . . . . . . . . . . . . . . . 323
C. Owen and
D. DeRosier A 13-A map of the actin-scruin filament
from the limulus acrosomal process . . . 337
L. W. Janson and
D. L. Taylor In vitro models of tail contraction and
cytoplasmic streaming in amoeboid cells 345
D. Masson and
T. E. Kreis Identification and molecular
characterization of E--MAP--115, a novel
microtubule-associated protein
predominantly expressed in epithelial
cells . . . . . . . . . . . . . . . . . 357
A. M. Mackay and
D. M. Eckley and
C. Chue and
W. C. Earnshaw Molecular analysis of the INCENPs (inner
centromere proteins): separate domains
are required for association with
microtubules during interphase and with
the central spindle during anaphase . . 373
M. T. Brown and
L. Goetsch and
L. H. Hartwell MIF2 is required for mitotic spindle
integrity during anaphase spindle
elongation in \bionameSaccharomyces
cerevisiae . . . . . . . . . . . . . . . 387
A. Spang and
I. Courtney and
U. Fackler and
M. Matzner and
E. Schiebel The calcium-binding protein cell
division cycle 31 of
\bionameSaccharomyces cerevisiae is a
component of the half bridge of the
spindle pole body . . . . . . . . . . . 405
L. Aigner and
P. Caroni Depletion of 43-kD growth-associated
protein in primary sensory neurons leads
to diminished formation and spreading of
growth cones . . . . . . . . . . . . . . 417
K. Ainger and
D. Avossa and
F. Morgan and
S. J. Hill and
C. Barry and
E. Barbarese and
J. H. Carson Transport and localization of exogenous
myelin basic protein mRNA microinjected
into oligodendrocytes . . . . . . . . . 431
P. A. Wight and
C. S. Duchala and
C. Readhead and
W. B. Macklin A myelin proteolipid protein--LacZ
fusion protein is developmentally
regulated and targeted to the myelin
membrane in transgenic mice . . . . . . 443
H. Funakoshi and
J. Frisén and
G. Barbany and
T. Timmusk and
O. Zachrisson and
V. M. Verge and
H. Persson Differential expression of mRNAs for
neurotrophins and their receptors after
axotomy of the sciatic nerve . . . . . . 455
F. J. Eidelman and
A. Fuks and
L. DeMarte and
M. Taheri and
C. P. Stanners Human carcinoembryonic antigen, an
intercellular adhesion molecule, blocks
fusion and differentiation of rat
myoblasts . . . . . . . . . . . . . . . 467
P. D. McCrea and
W. M. Brieher and
B. M. Gumbiner Induction of a secondary body axis in
\bionameXenopus by antibodies to
beta-catenin . . . . . . . . . . . . . . 477
F. P. Lindberg and
H. D. Gresham and
E. Schwarz and
E. J. Brown Molecular cloning of integrin-associated
protein: an immunoglobulin family member
with multiple membrane-spanning domains
implicated in alpha v beta $3$-dependent
ligand binding . . . . . . . . . . . . . 485
D. Lourim and
G. Krohne Membrane-associated lamins in
\bionameXenopus egg extracts:
identification of two vesicle
populations . . . . . . . . . . . . . . 501
C. Schlüter and
M. Duchrow and
C. Wohlenberg and
M. H. Becker and
G. Key and
H. D. Flad and
J. Gerdes The cell proliferation-associated
antigen of antibody Ki-67: a very large,
ubiquitous nuclear protein with numerous
repeated elements, representing a new
kind of cell cycle-maintaining proteins 513
A. M. Whalen and
R. Steward Dissociation of the dorsal-cactus
complex and phosphorylation of the
dorsal protein correlate with the
nuclear localization of dorsal . . . . . 523
A. P. Spong and
S. Subramani Cloning and characterization of PAS5: a
gene required for peroxisome biogenesis
in the methylotrophic yeast Pichia
pastoris . . . . . . . . . . . . . . . . 535
Y. F. Xu and
A. N. Meyer and
M. K. Webster and
B. A. Lee and
D. J. Donoghue The v-sis protein retains biological
activity as a type II membrane protein
when anchored by various signal-anchor
domains, including the hydrophobic
domain of the bovine papilloma virus E5
oncoprotein . . . . . . . . . . . . . . 549
L. M. Traub and
J. A. Ostrom and
S. Kornfeld Biochemical dissection of AP-1
recruitment onto Golgi membranes . . . . 561
M. B. Feany and
A. G. Yee and
M. L. Delvy and
K. M. Buckley The synaptic vesicle proteins SV2,
synaptotagmin and synaptophysin are
sorted to separate cellular compartments
in CHO fibroblasts . . . . . . . . . . . 575
I. Hide and
J. P. Bennett and
A. Pizzey and
G. Boonen and
D. Bar-Sagi and
B. D. Gomperts and
P. E. Tatham Degranulation of individual mast cells
in response to Ca$^{2+}$ and guanine
nucleotides: an all-or-none event . . . 585
M. P. Lisanti and
Z. L. Tang and
M. Sargiacomo Caveolin forms a hetero-oligomeric
protein complex that interacts with an
apical GPI-linked protein: implications
for the biogenesis of caveolae . . . . . 595
J. M. Verbavatz and
D. Brown and
I. Saboli\'c and
G. Valenti and
D. A. Ausiello and
A. N. Van Hoek and
T. Ma and
A. S. Verkman Tetrameric assembly of CHIP28 water
channels in liposomes and cell
membranes: a freeze-fracture study . . . 605
T. Okagaki and
F. E. Weber and
D. A. Fischman and
K. T. Vaughan and
T. Mikawa and
F. C. Reinach The major myosin-binding domain of
skeletal muscle MyBP--C (C protein)
resides in the COOH-terminal,
immunoglobulin C2 motif . . . . . . . . 619
J. G. Tidball and
M. J. Spencer PDGF stimulation induces phosphorylation
of talin and cytoskeletal reorganization
in skeletal muscle . . . . . . . . . . . 627
A. B. Verkhovsky and
G. G. Borisy Non-sarcomeric mode of myosin II
organization in the fibroblast lamellum 637
D. Y. Wu and
D. J. Goldberg Regulated tyrosine phosphorylation at
the tips of growth cone filopodia . . . 653
M. M. Heck and
A. Pereira and
P. Pesavento and
Y. Yannoni and
A. C. Spradling and
L. S. Goldstein The kinesin-like protein KLP61F is
essential for mitosis in
\bionameDrosophila . . . . . . . . . . . 665
B. D. Wright and
M. Terasaki and
J. M. Scholey Roles of kinesin and kinesin-like
proteins in sea urchin embryonic cell
division: evaluation using antibody
microinjection . . . . . . . . . . . . . 681
T. S. Stappenbeck and
E. A. Bornslaeger and
C. M. Corcoran and
H. H. Luu and
M. L. Virata and
K. J. Green Functional analysis of desmoplakin
domains: specification of the
interaction with keratin versus vimentin
intermediate filament networks . . . . . 691
B. T. Kren and
N. M. Kumar and
S. Q. Wang and
N. B. Gilula and
C. J. Steer Differential regulation of multiple gap
junction transcripts and proteins during
rat liver regeneration . . . . . . . . . 707
P. B. Scotland and
M. Colledge and
I. Melnikova and
Z. Dai and
S. C. Froehner Clustering of the acetylcholine receptor
by the 43-kD protein: involvement of the
zinc finger domain . . . . . . . . . . . 719
W. D. Phillips and
P. G. Noakes and
S. L. Roberds and
K. P. Campbell and
J. P. Merlie Clustering and immobilization of
acetylcholine receptors by the 43-kD
protein: a possible role for
dystrophin-related protein . . . . . . . 729
E. Wilson and
Q. Mai and
K. Sudhir and
R. H. Weiss and
H. E. Ives Mechanical strain induces growth of
vascular smooth muscle cells via
autocrine action of PDGF . . . . . . . . 741
S. K. Samuel and
R. A. Hurta and
M. A. Spearman and
J. A. Wright and
E. A. Turley and
A. H. Greenberg TGF-beta 1 stimulation of cell
locomotion utilizes the hyaluronan
receptor RHAMM and hyaluronan . . . . . 749
D. C. Love and
J. D. Esko and
D. M. Mosser A heparin-binding activity on Leishmania
amastigotes which mediates adhesion to
cellular proteoglycans . . . . . . . . . 759
M. P. Rout and
G. Blobel Isolation of the yeast nuclear pore
complex . . . . . . . . . . . . . . . . 771
G. Schlenstedt and
E. Hurt and
V. Doye and
P. A. Silver Reconstitution of nuclear protein
transport with semi-intact yeast cells 785
T. Connolly and
R. Gilmore GTP hydrolysis by complexes of the
signal recognition particle and the
signal recognition particle receptor . . 799
R. Oko and
L. Hermo and
P. T. Chan and
A. Fazel and
J. J. Bergeron The cytoplasmic droplet of rat
epididymal spermatozoa contains saccular
elements with Golgi characteristics . . 809
C. DeNardi and
S. Ausoni and
P. Moretti and
L. Gorza and
M. Velleca and
M. Buckingham and
S. Schiaffino Type 2X-myosin heavy chain is coded by a
muscle fiber type-specific and
developmentally regulated gene . . . . . 823
D. J. Fishkind and
Y. L. Wang Orientation and three-dimensional
organization of actin filaments in
dividing cultured cells . . . . . . . . 837
E. A. Vaisberg and
M. P. Koonce and
J. R. McIntosh Cytoplasmic dynein plays a role in
mammalian mitotic spindle formation . . 849
J. Kuang and
C. L. Ashorn At least two kinases phosphorylate the
MPM-2 epitope during \bionameXenopus
oocyte maturation . . . . . . . . . . . 859
Y. G. Yueh and
R. C. Crain Deflagellation of \bionameChlamydomonas
reinhardtii follows a rapid transitory
accumulation of inositol
1,4,5-trisphosphate and requires
Ca$^{2+}$ entry . . . . . . . . . . . . 869
S. H. Kim and
K. A. Roth and
A. R. Moser and
J. I. Gordon Transgenic mouse models that explore the
multistep hypothesis of intestinal
neoplasia . . . . . . . . . . . . . . . 877
B. A. McCormick and
S. P. Colgan and
C. Delp-Archer and
S. I. Miller and
J. L. Madara Salmonella typhimurium attachment to
human intestinal epithelial monolayers:
transcellular signalling to
subepithelial neutrophils . . . . . . . 895
V. Drozdoff and
W. J. Pledger Commitment to differentiation and
expression of early differentiation
markers in murine keratinocytes in vitro
are regulated independently of
extracellular calcium concentrations . . 909
I. Asahina and
T. K. Sampath and
I. Nishimura and
P. V. Hauschka Human osteogenic protein-1 induces both
chondroblastic and osteoblastic
differentiation of osteoprogenitor cells
derived from newborn rat calvaria . . . 921
T. P. O'Connor and
D. Bentley Accumulation of actin in subsets of
pioneer growth cone filopodia in
response to neural and epithelial
guidance cues in situ . . . . . . . . . 935
J. W. Hell and
R. E. Westenbroek and
C. Warner and
M. K. Ahlijanian and
W. Prystay and
M. M. Gilbert and
T. P. Snutch and
W. A. Catterall Identification and differential
subcellular localization of the neuronal
class C and class D L-type calcium
channel alpha 1 subunits . . . . . . . . 949
Y. Nemoto and
J. Ikeda and
K. Katoh and
H. Koshimoto and
Y. Yoshihara and
K. Mori R2D5 antigen: a calcium-binding
phosphoprotein predominantly expressed
in olfactory receptor neurons . . . . . 963
C. E. Schmidt and
A. F. Horwitz and
D. A. Lauffenburger and
M. P. Sheetz Integrin-cytoskeletal interactions in
migrating fibroblasts are dynamic,
asymmetric, and regulated . . . . . . . 977
J. D. Hildebrand and
M. D. Schaller and
J. T. Parsons Identification of sequences required for
the efficient localization of the focal
adhesion kinase, pp125FAK, to cellular
focal adhesions . . . . . . . . . . . . 993
M. R. Campanero and
M. A. del Pozo and
A. G. Arroyo and
P. Sánchez-Mateos and
T. Hernández-Caselles and
A. Craig and
R. Pulido and
F. Sánchez-Madrid ICAM-3 interacts with LFA-1 and
regulates the LFA-1/ICAM-1 cell adhesion
pathway . . . . . . . . . . . . . . . . 1007
L. M. Shaw and
A. M. Mercurio Regulation of alpha 6 beta 1 integrin
laminin receptor function by the
cytoplasmic domain of the alpha 6
subunit . . . . . . . . . . . . . . . . 1017
G. Klein and
S. Beck and
C. A. Müller Tenascin is a cytoadhesive extracellular
matrix component of the human
hematopoietic microenvironment . . . . . 1027
M. Ekblom and
R. Fässler and
B. Tomasini-Johansson and
K. Nilsson and
P. Ekblom Downregulation of tenascin expression by
glucocorticoids in bone marrow stromal
cells and in fibroblasts . . . . . . . . 1037
S. Tsukita and
M. Itoh and
A. Nagafuchi and
S. Yonemura and
S. Tsukita Submembranous junctional plaque proteins
include potential tumor suppressor
molecules . . . . . . . . . . . . . . . 1049
M. Antoniou and
M. Carmo-Fonseca and
J. Ferreira and
A. I. Lamond Nuclear organization of splicing snRNPs
during differentiation of murine
erythroleukemia cells in vitro . . . . . 1055
D. Pérez-Morga and
P. T. Englund The structure of replicating kinetoplast
DNA networks . . . . . . . . . . . . . . 1069
C. Yan and
T. Mél\`ese Multiple regions of NSR1 are sufficient
for accumulation of a fusion protein
within the nucleolus . . . . . . . . . . 1081
M. N. Seaman and
C. L. Ball and
M. S. Robinson Targeting and mistargeting of plasma
membrane adaptors in vitro . . . . . . . 1093
L. H. Wang and
K. G. Rothberg and
R. G. Anderson Mis-assembly of clathrin lattices on
endosomes reveals a regulatory switch
for coated pit formation . . . . . . . . 1107
T. Harder and
V. Gerke The subcellular distribution of early
endosomes is affected by the annexin
II2p11(2) complex . . . . . . . . . . . 1119
J. W. Zhang and
Y. Han and
P. B. Lazarow Novel peroxisome clustering mutants and
peroxisome biogenesis mutants of
\bionameSaccharomyces cerevisiae . . . . 1133
B. Aroeti and
P. A. Kosen and
I. D. Kuntz and
F. E. Cohen and
K. E. Mostov Mutational and secondary structural
analysis of the basolateral sorting
signal of the polymeric immunoglobulin
receptor . . . . . . . . . . . . . . . . 1149
B. E. Flucher and
S. B. Andrews and
S. Fleischer and
A. R. Marks and
A. Caswell and
J. A. Powell Triad formation: organization and
function of the sarcoplasmic reticulum
calcium release channel and triadin in
normal and dysgenic muscle in vitro . . 1161
J. V. Kilmartin and
S. L. Dyos and
D. Kershaw and
J. T. Finch A spacer protein in the
\bionameSaccharomyces cerevisiae spindle
poly body whose transcript is cell
cycle-regulated . . . . . . . . . . . . 1175
X. Chen and
R. K. Cook and
P. A. Rubenstein Yeast actin with a mutation in the
``hydrophobic plug'' between subdomains
3 and 4 (L266D) displays a
cold-sensitive polymerization defect . . 1185
K. Djabali and
A. Zissopoulou and
M. J. de Hoop and
S. D. Georgatos and
C. G. Dotti Peripherin expression in hippocampal
neurons induced by muscle soluble
factor(s) . . . . . . . . . . . . . . . 1197
T. L. Deckwerth and
E. M. Johnson Temporal analysis of events associated
with programmed cell death (apoptosis)
of sympathetic neurons deprived of nerve
growth factor . . . . . . . . . . . . . 1207
S. Einheber and
T. A. Milner and
F. Giancotti and
J. L. Salzer Axonal regulation of Schwann cell
integrin expression suggests a role for
alpha 6 beta 4 in myelination . . . . . 1223
K. Nishiyama and
T. Funai and
S. Yokota and
A. Ichiyama ATP-dependent degradation of a mutant
serine: pyruvate/alanine: glyoxylate
aminotransferase in a primary
hyperoxaluria type 1 case . . . . . . . 1237
Y. Sato and
F. Okada and
M. Abe and
T. Seguchi and
M. Kuwano and
S. Sato and
A. Furuya and
N. Hanai and
T. Tamaoki The mechanism for the activation of
latent TGF-beta during co-culture of
endothelial cells and smooth muscle
cells: cell-type specific targeting of
latent TGF-beta to smooth muscle cells 1249
U. Sung and
J. J. O'Rear and
P. D. Yurchenco Cell and heparin binding in the distal
long arm of laminin: identification of
active and cryptic sites with
recombinant and hybrid glycoprotein . . 1255
T. C. Pan and
T. Sasaki and
R. Z. Zhang and
R. Fässler and
R. Timpl and
M. L. Chu Structure and expression of fibulin-2, a
novel extracellular matrix protein with
multiple EGF-like repeats and consensus
motifs for calcium binding . . . . . . . 1269
R. Bar-Shavit and
Y. Eskohjido and
J. W. Fenton and
J. D. Esko and
I. Vlodavsky Thrombin adhesive properties: induction
by plasmin and heparan sulfate . . . . . 1279
E. L. Palmer and
C. Rüegg and
R. Ferrando and
R. Pytela and
D. Sheppard Sequence and tissue distribution of the
integrin alpha 9 subunit, a novel
partner of beta 1 that is widely
distributed in epithelia and muscle . . 1289
G. D. Longmore and
S. S. Watowich and
D. J. Hilton and
H. F. Lodish The erythropoietin receptor: its role in
hematopoiesis and myeloproliferative
diseases . . . . . . . . . . . . . . . . 1305
B. M. Gumbiner Breaking through the tight junction
barrier . . . . . . . . . . . . . . . . 1631
M. Ruhl and
M. Himmelspach and
G. M. Bahr and
F. Hammerschmid and
H. Jaksche and
B. Wolff and
H. Aschauer and
G. K. Farrington and
H. Probst and
D. Bevec Eukaryotic initiation factor 5A is a
cellular target of the human
immunodeficiency virus type 1 Rev
activation domain mediating
trans-activation . . . . . . . . . . . . 1309
Y. Kubota and
H. Takisawa Determination of initiation of DNA
replication before and after nuclear
formation in \bionameXenopus egg cell
free extracts . . . . . . . . . . . . . 1321
V. C. Cordes and
S. Reidenbach and
A. Köhler and
N. Stuurman and
R. van Driel and
W. W. Franke Intranuclear filaments containing a
nuclear pore complex protein . . . . . . 1333
N. Wilken and
U. Kossner and
J. L. Senécal and
U. Scheer and
M. C. Dabauvalle Nup180, a novel nuclear pore complex
protein localizing to the cytoplasmic
ring and associated fibrils . . . . . . 1345
J. L. Brodsky and
R. Schekman A Sec63p--BiP complex from yeast is
required for protein translocation in a
reconstituted proteoliposome . . . . . . 1355
G. Tanigawa and
L. Orci and
M. Amherdt and
M. Ravazzola and
J. B. Helms and
J. E. Rothman Hydrolysis of bound GTP by ARF protein
triggers uncoating of Golgi-derived
COP-coated vesicles . . . . . . . . . . 1365
F. Aniento and
N. Emans and
G. Griffiths and
J. Gruenberg Cytoplasmic dynein-dependent vesicular
transport from early to late endosomes 1373
J. N. Myers and
I. Tabas and
N. L. Jones and
F. R. Maxfield Beta-very low density lipoprotein is
sequestered in surface-connected tubules
in mouse peritoneal macrophages . . . . 1389
L. S. Kean and
R. S. Fuller and
J. W. Nichols Retrograde lipid traffic in yeast:
identification of two distinct pathways
for internalization of
fluorescent-labeled phosphatidylcholine
from the plasma membrane . . . . . . . . 1403
F. Jaisser and
J. D. Horisberger and
K. Geering and
B. C. Rossier Mechanisms of urinary K+ and H+
excretion: primary structure and
functional expression of a novel
H,K--ATPase . . . . . . . . . . . . . . 1421
D. J. Miller and
X. Gong and
G. Decker and
B. D. Shur Egg cortical granule
N-acetylglucosaminidase is required for
the mouse \bionamezona block to
polyspermy . . . . . . . . . . . . . . . 1431
P. Vanderhaeghen and
S. Schurmans and
G. Vassart and
M. Parmentier Olfactory receptors are displayed on dog
mature sperm cells . . . . . . . . . . . 1441
H. Kuwayama and
S. Ishida and
P. J. Van Haastert Non-chemotactic \bionameDictyostelium
discoideum mutants with altered cGMP
signal transduction . . . . . . . . . . 1453
W. Chan and
E. Kordeli and
V. Bennett $ 440$-kD ankyrinB: structure of the
major developmentally regulated domain
and selective localization in
unmyelinated axons . . . . . . . . . . . 1463
D. N. Mastronarde and
K. L. McDonald and
R. Ding and
J. R. McIntosh Interpolar spindle microtubules in PTK
cells . . . . . . . . . . . . . . . . . 1475
C. Maison and
H. Horstmann and
S. D. Georgatos Regulated docking of nuclear membrane
vesicles to vimentin filaments during
mitosis . . . . . . . . . . . . . . . . 1491
A. Merdes and
F. Gounari and
S. D. Georgatos The 47-kD lens-specific protein phakinin
is a tailless intermediate filament
protein and an assembly partner of
filensin . . . . . . . . . . . . . . . . 1507
S. Heins and
P. C. Wong and
S. Müller and
K. Goldie and
D. W. Cleveland and
U. Aebi The rod domain of NF--L determines
neurofilament architecture, whereas the
end domains specify filament assembly
and network formation . . . . . . . . . 1517
K. Gundersen and
J. R. Sanes and
J. P. Merlie Neural regulation of muscle
acetylcholine receptor epsilon- and
alpha-subunit gene promoters in
transgenic mice . . . . . . . . . . . . 1535
K. Ravid and
Y. C. Li and
H. B. Rayburn and
R. D. Rosenberg Targeted expression of a conditional
oncogene in hematopoietic cells of
transgenic mice . . . . . . . . . . . . 1545
T. E. Allsopp and
M. Robinson and
S. Wyatt and
A. M. Davies Ectopic trkA expression mediates a NGF
survival response in NGF-independent
sensory neurons but not in
parasympathetic neurons . . . . . . . . 1555
M. Lorenzo and
A. M. Valverde and
T. Teruel and
M. Benito IGF-I is a mitogen involved in
differentiation-related gene expression
in fetal rat brown adipocytes . . . . . 1567
I. Duluc and
B. Jost and
J. N. Freund Multiple levels of control of the stage-
and region-specific expression of rat
intestinal lactase . . . . . . . . . . . 1577
D. Peck and
F. S. Walsh Differential effects of over-expressed
neural cell adhesion molecule isoforms
on myoblast fusion . . . . . . . . . . . 1587
R. Löfgren and
J. Ng-Sikorski and
A. Sjölander and
T. Andersson Beta 2 integrin engagement triggers
actin polymerization and
phosphatidylinositol trisphosphate
formation in non-adherent human
neutrophils . . . . . . . . . . . . . . 1597
L. E. Stephens and
J. E. Sonne and
M. L. Fitzgerald and
C. H. Damsky Targeted deletion of beta 1 integrins in
F9 embryonal carcinoma cells affects
morphological differentiation but not
tissue-specific gene expression . . . . 1607
A. V. Strunnikov and
V. L. Larionov and
D. Koshland SMC1: an essential yeast gene encoding a
putative head-rod-tail protein is
required for nuclear division and
defines a new ubiquitous protein family 1635
F. Melchior and
B. Paschal and
J. Evans and
L. Gerace Inhibition of nuclear protein import by
nonhydrolyzable analogues of GTP and
identification of the small GTPase
Ran/TC4 as an essential transport factor 1649
I. Firmbach-Kraft and
R. Stick The role of CaaX-dependent modifications
in membrane association of
\bionameXenopus nuclear lamin B3 during
meiosis and the fate of B3 in
transfected mitotic cells . . . . . . . 1661
A. S. Belmont and
Y. Zhai and
A. Thilenius Lamin B distribution and association
with peripheral chromatin revealed by
optical sectioning and electron
microscopy tomography . . . . . . . . . 1671
B. Thorens and
N. Gérard and
N. Dériaz GLUT2 surface expression and
intracellular transport via the
constitutive pathway in pancreatic beta
cells and insulinoma: evidence for a
block in trans-Golgi network exit by
brefeldin A . . . . . . . . . . . . . . 1687
R. Miquelis and
J. Courageot and
A. Jacq and
O. Blanck and
C. Perrin and
P. Bastiani Intracellular routing of GLcNAc-bearing
molecules in thyrocytes: selective
recycling through the Golgi apparatus 1695
P. K. Tan and
N. G. Davis and
G. F. Sprague and
G. S. Payne Clathrin facilitates the internalization
of seven transmembrane segment receptors
for mating pheromones in yeast . . . . . 1707
P. Diestelkötter and
W. W. Just In vitro insertion of the 22-kD
peroxisomal membrane protein into
isolated rat liver peroxisomes . . . . . 1717
O. Kuge and
S. Hara-Kuge and
L. Orci and
M. Ravazzola and
M. Amherdt and
G. Tanigawa and
F. T. Wieland and
J. E. Rothman zeta-COP, a subunit of coatomer, is
required for COP-coated vesicle assembly 1727
M. H. Yuk and
H. F. Lodish Two pathways for the degradation of the
H2 subunit of the asialoglycoprotein
receptor in the endoplasmic reticulum 1735
P. Jaunin and
F. Jaisser and
A. T. Beggah and
K. Takeyasu and
P. Mangeat and
B. C. Rossier and
J. D. Horisberger and
K. Geering Role of the transmembrane and
extracytoplasmic domain of beta subunits
in subunit assembly, intracellular
transport, and functional expression of
Na,K-pumps . . . . . . . . . . . . . . . 1751
G. Ihrke and
E. B. Neufeld and
T. Meads and
M. R. Shanks and
D. Cassio and
M. Laurent and
T. A. Schroer and
R. E. Pagano and
A. L. Hubbard WIF-B cells: an in vitro model for
studies of hepatocyte polarity . . . . . 1761
M. Furuse and
T. Hirase and
M. Itoh and
A. Nagafuchi and
S. Yonemura and
S. Tsukita and
S. Tsukita Occludin: a novel integral membrane
protein localizing at tight junctions 1777
K. S. Ha and
J. H. Exton Activation of actin polymerization by
phosphatidic acid derived from
phosphatidylcholine in IIC9 fibroblasts 1789
J. K. Lee and
R. S. Coyne and
R. R. Dubreuil and
L. S. Goldstein and
D. Branton Cell shape and interaction defects in
alpha-spectrin mutants of
\bionameDrosophila melanogaster . . . . 1797
V. I. Rodionov and
F. K. Gyoeva and
E. Tanaka and
A. D. Bershadsky and
J. M. Vasiliev and
V. I. Gelfand Microtubule-dependent control of cell
shape and pseudopodial activity is
inhibited by the antibody to kinesin
motor domain . . . . . . . . . . . . . . 1811
C. Mazzoni and
P. Zarov and
A. Rambourg and
C. Mann The SLT2 (MPK1) MAP kinase homolog is
involved in polarized cell growth in
\bionameSaccharomyces cerevisiae . . . . 1821
N. Sharma and
G. D'Arcangelo and
A. Kleinlaus and
S. Halegoua and
J. S. Trimmer Nerve growth factor regulates the
abundance and distribution of K+
channels in PC12 cells . . . . . . . . . 1835
F. Benfenati and
F. Valtorta and
M. C. Rossi and
F. Onofri and
T. Sihra and
P. Greengard Interactions of synapsin I with
phospholipids: possible role in synaptic
vesicle clustering and in the
maintenance of bilayer structures . . . 1845
R. S. Bradley and
P. Cowin and
A. M. Brown Expression of Wnt-1 in PC12 cells
results in modulation of plakoglobin and
E-cadherin and increased cellular
adhesion . . . . . . . . . . . . . . . . 1857
B. Fredette and
U. Rutishauser and
L. Landmesser Regulation and activity-dependence of
N-cadherin, NCAM isoforms, and
polysialic acid on chick myotubes during
development . . . . . . . . . . . . . . 1867
S. S. Evans and
R. P. Collea and
M. M. Appenheimer and
S. O. Gollnick Interferon-alpha induces the expression
of the L-selectin homing receptor in
human B lymphoid cells . . . . . . . . . 1889
G. M. Lee and
B. Johnstone and
K. Jacobson and
B. Caterson The dynamic structure of the
pericellular matrix on living cells . . 1899
J. C. Reed Bcl-2 and the regulation of programmed
cell death . . . . . . . . . . . . . . . 1
X. Li and
W. Shou and
M. Kloc and
B. A. Reddy and
L. D. Etkin Cytoplasmic retention of \bionameXenopus
nuclear factor 7 before the mid blastula
transition uses a unique anchoring
mechanism involving a retention domain
and several phosphorylation sites . . . 7
M. A. Félix and
C. Antony and
M. Wright and
B. Maro Centrosome assembly in vitro: role of
gamma-tubulin recruitment in
\bionameXenopus sperm aster formation 19
S. L. Milgram and
B. A. Eipper and
R. E. Mains Differential trafficking of soluble and
integral membrane secretory
granule-associated proteins . . . . . . 33
B. P. Jena and
F. D. Gumkowski and
E. M. Konieczko and
G. F. von Mollard and
R. Jahn and
J. D. Jamieson Redistribution of a rab3-like
GTP-binding protein from secretory
granules to the Golgi complex in
pancreatic acinar cells during regulated
exocytosis . . . . . . . . . . . . . . . 43
J. Krijnse-Locker and
M. Ericsson and
P. J. Rottier and
G. Griffiths Characterization of the budding
compartment of mouse hepatitis virus:
evidence that transport from the RER to
the Golgi complex requires only one
vesicular transport step . . . . . . . . 55
C. R. Mackay and
H. J. Terpe and
R. Stauder and
W. L. Marston and
H. Stark and
U. Günthert Expression and modulation of CD44
variant isoforms in humans . . . . . . . 71
M. Barroso and
E. S. Sztul Basolateral to apical transcytosis in
polarized cells is indirect and involves
BFA and trimeric G protein sensitive
passage through the apical endosome . . 83
A. Zahraoui and
G. Joberty and
M. Arpin and
J. J. Fontaine and
R. Hellio and
A. Tavitian and
D. Louvard A small rab GTPase is distributed in
cytoplasmic vesicles in non polarized
cells but colocalizes with the tight
junction marker ZO-1 in polarized
epithelial cells . . . . . . . . . . . . 101
A. W. Crawford and
J. D. Pino and
M. C. Beckerle Biochemical and molecular
characterization of the chicken
cysteine-rich protein, a developmentally
regulated LIM-domain protein that is
associated with the actin cytoskeleton 117
Y. Yamakita and
S. Yamashiro and
F. Matsumura In vivo phosphorylation of regulatory
light chain of myosin II during mitosis
of cultured cells . . . . . . . . . . . 129
M. T. Lupa and
J. H. Caldwell Sodium channels aggregate at former
synaptic sites in innervated and
denervated regenerating muscles . . . . 139
C. S. Stipp and
E. D. Litwack and
A. D. Lander Cerebroglycan: an integral membrane
heparan sulfate proteoglycan that is
unique to the developing nervous system
and expressed specifically during
neuronal differentiation . . . . . . . . 149
D. J. Carey and
R. C. Stahl and
G. Cizmeci-Smith and
V. K. Asundi Syndecan-1 expressed in Schwann cells
causes morphological transformation and
cytoskeletal reorganization and
associates with actin during cell
spreading . . . . . . . . . . . . . . . 161
J. Taipale and
K. Miyazono and
C. H. Heldin and
J. Keski-Oja Latent transforming growth factor-beta 1
associates to fibroblast extracellular
matrix via latent TGF-beta binding
protein . . . . . . . . . . . . . . . . 171
R. F. Nicosia and
G. P. Tuszynski Matrix-bound thrombospondin promotes
angiogenesis in vitro . . . . . . . . . 183
H. M. DeLisser and
J. Chilkotowsky and
H. C. Yan and
M. L. Daise and
C. A. Buck and
S. M. Albelda Deletions in the cytoplasmic domain of
platelet-endothelial cell adhesion
molecule-1 (PECAM-1, CD31) result in
changes in ligand binding properties . . 195
A. Barth and
A. Müller-Taubenberger and
P. Taranto and
G. Gerisch Replacement of the phospholipid-anchor
in the contact site A glycoprotein of
\bionameD. discoideum by a transmembrane
region does not impede cell adhesion but
reduces residence time on the cell
surface . . . . . . . . . . . . . . . . 205
C. L. Rieder and
E. D. Salmon Motile kinetochores and polar ejection
forces dictate chromosome position on
the vertebrate mitotic spindle . . . . . 223
P. Hartl and
E. Olson and
T. Dang and
D. J. Forbes Nuclear assembly with lambda DNA in
fractionated \bionameXenopus egg
extracts: an unexpected role for
glycogen in formation of a higher order
chromatin intermediate . . . . . . . . . 235
R. T. O'Keefe and
A. Mayeda and
C. L. Sadowski and
A. R. Krainer and
D. L. Spector Disruption of pre-mRNA splicing in vivo
results in reorganization of splicing
factors . . . . . . . . . . . . . . . . 249
W. Hackl and
U. Fischer and
R. Lührmann A 69-kD protein that associates
reversibly with the Sm core domain of
several spliceosomal snRNP species . . . 261
T. P. McGee and
H. B. Skinner and
E. A. Whitters and
S. A. Henry and
V. A. Bankaitis A phosphatidylinositol transfer protein
controls the phosphatidylcholine content
of yeast Golgi membranes . . . . . . . . 273
C. J. Zhang and
A. G. Rosenwald and
M. C. Willingham and
S. Skuntz and
J. Clark and
R. A. Kahn Expression of a dominant allele of human
ARF1 inhibits membrane traffic in vivo 289
E. Smythe and
P. D. Smith and
S. M. Jacob and
J. Theobald and
S. E. Moss Endocytosis occurs independently of
annexin VI in human A431 cells . . . . . 301
E. J. Smart and
D. C. Foster and
Y. S. Ying and
B. A. Kamen and
R. G. Anderson Protein kinase C activators inhibit
receptor-mediated potocytosis by
preventing internalization of caveolae 307
S. E. Brockerhoff and
R. C. Stevens and
T. N. Davis The unconventional myosin, Myo2p, is a
calmodulin target at sites of cell
growth in \bionameSaccharomyces
cerevisiae . . . . . . . . . . . . . . . 315
R. A. Van Etten and
P. K. Jackson and
D. Baltimore and
M. C. Sanders and
P. T. Matsudaira and
P. A. Janmey The COOH terminus of the c--Abl tyrosine
kinase contains distinct F- and G-actin
binding domains with bundling activity 325
M. F. Schmid and
J. M. Agris and
J. Jakana and
P. Matsudaira and
W. Chiu Three-dimensional structure of a single
filament in the Limulus acrosomal
bundle: scruin binds to homologous
helix-loop-beta motifs in actin . . . . 341
K. W. Cunningham and
G. R. Fink Calcineurin-dependent growth control in
\bionameSaccharomyces cerevisiae mutants
lacking PMC1, a homolog of plasma
membrane Ca$^{2+}$ ATPases . . . . . . . 351
M. Lotz and
I. Clark-Lewis and
V. Ganu HIV-1 transactivator protein Tat induces
proliferation and TGF beta expression in
human articular chondrocytes . . . . . . 365
E. Koivunen and
B. Wang and
E. Ruoslahti Isolation of a highly specific ligand
for the alpha 5 beta 1 integrin from a
phage display library . . . . . . . . . 373
R. Vuolteenaho and
M. Nissinen and
K. Sainio and
M. Byers and
R. Eddy and
H. Hirvonen and
T. B. Shows and
H. Sariola and
E. Engvall and
K. Tryggvason Human laminin M chain (merosin):
complete primary structure, chromosomal
assignment, and expression of the M and
A chain in human fetal tissues . . . . . 381
F. Grinnell Fibroblasts, myofibroblasts, and wound
contraction . . . . . . . . . . . . . . 401
P. Slusarewicz and
T. Nilsson and
N. Hui and
R. Watson and
G. Warren Isolation of a matrix that binds medial
Golgi enzymes . . . . . . . . . . . . . 405
Z. Elazar and
L. Orci and
J. Ostermann and
M. Amherdt and
G. Tanigawa and
J. E. Rothman ADP-ribosylation factor and coatomer
couple fusion to vesicle budding . . . . 415
T. Oka and
A. Nakano Inhibition of GTP hydrolysis by Sar1p
causes accumulation of vesicles that are
a functional intermediate of the
ER-to-Golgi transport in yeast . . . . . 425
S. A. Green and
H. Setiadi and
R. P. McEver and
R. B. Kelly The cytoplasmic domain of P-selectin
contains a sorting determinant that
mediates rapid degradation in lysosomes 435
H. G. Elmendorf and
K. Haldar Plasmodium falciparum exports the Golgi
marker sphingomyelin synthase into a
tubovesicular network in the cytoplasm
of mature erythrocytes . . . . . . . . . 449
K. J. Kotz and
M. A. McNiven Intracellular calcium and cAMP regulate
directional pigment movements in teleost
erythrophores . . . . . . . . . . . . . 463
B. D. Williams and
R. H. Waterston Genes critical for muscle development
and function in \bionameCaenorhabditis
elegans identified through lethal
mutations . . . . . . . . . . . . . . . 475
M. C. Hresko and
B. D. Williams and
R. H. Waterston Assembly of body wall muscle and muscle
cell attachment structures in
\bionameCaenorhabditis elegans . . . . . 491
B. D. Page and
L. L. Satterwhite and
M. D. Rose and
M. Snyder Localization of the Kar3 kinesin heavy
chain-related protein requires the Cik1
interacting protein . . . . . . . . . . 507
S. I. Patterson and
J. H. Skene Novel inhibitory action of tunicamycin
homologues suggests a role for dynamic
protein fatty acylation in growth
cone-mediated neurite extension . . . . 521
S. N. Edwards and
A. M. Tolkovsky Characterization of apoptosis in
cultured rat sympathetic neurons after
nerve growth factor withdrawal . . . . . 537
P. Chen and
K. Gupta and
A. Wells Cell movement elicited by epidermal
growth factor receptor requires kinase
and autophosphorylation but is separable
from mitogenesis . . . . . . . . . . . . 547
F. López-Casillas and
H. M. Payne and
J. L. Andres and
J. Massagué Betaglycan can act as a dual modulator
of TGF-beta access to signaling
receptors: mapping of ligand binding and
GAG attachment sites . . . . . . . . . . 557
P. Van Vlasselaer and
B. Borremans and
U. van Gorp and
J. R. Dasch and
R. De Waal-Malefyt Interleukin 10 inhibits transforming
growth factor-beta (TGF-beta) synthesis
required for osteogenic commitment of
mouse bone marrow cells . . . . . . . . 569
C. Gentili and
R. Doliana and
P. Bet and
G. Campanile and
A. Colombatti and
F. D. Cancedda and
R. Cancedda Ovotransferrin and ovotransferrin
receptor expression during
chondrogenesis and endochondral bone
formation in developing chick embryo . . 579
K. J. Hodivala and
F. M. Watt Evidence that cadherins play a role in
the downregulation of integrin
expression that occurs during
keratinocyte terminal differentiation 589
L. Osborn and
C. Vassallo and
B. G. Browning and
R. Tizard and
D. O. Haskard and
C. D. Benjamin and
I. Dougas and
T. Kirchhausen Arrangement of domains, and amino acid
residues required for binding of
vascular cell adhesion molecule-1 to its
counter-receptor VLA-4 (alpha 4 beta 1) 601
G. S. Kansas and
K. B. Saunders and
K. Ley and
A. Zakrzewicz and
R. M. Gibson and
B. C. Furie and
B. Furie and
T. F. Tedder A role for the epidermal growth
factor-like domain of P-selectin in
ligand recognition and cell adhesion . . 609
S. M. Frisch and
H. Francis Disruption of epithelial cell-matrix
interactions induces apoptosis . . . . . 619
A. Jarmolowski and
W. C. Boelens and
E. Izaurralde and
I. W. Mattaj Nuclear export of different classes of
RNA is mediated by specific factors . . 627
T. A. Harkness and
F. E. Nargang and
I. van der Klei and
W. Neupert and
R. Lill A crucial role of the mitochondrial
protein import receptor MOM19 for the
biogenesis of mitochondria . . . . . . . 637
J. Alcalde and
G. Egea and
I. V. Sandoval gp74 a membrane glycoprotein of the
cis-Golgi network that cycles through
the endoplasmic reticulum and
intermediate compartment . . . . . . . . 649
P. Thomas and
A. K. Lee and
J. G. Wong and
W. Almers A triggered mechanism retrieves membrane
in seconds after Ca(2+)-stimulated
exocytosis in single pituitary cells . . 667
M. Desjardins and
L. A. Huber and
R. G. Parton and
G. Griffiths Biogenesis of phagolysosomes proceeds
through a sequential series of
interactions with the endocytic
apparatus . . . . . . . . . . . . . . . 677
L. J. Hewlett and
A. R. Prescott and
C. Watts The coated pit and macropinocytic
pathways serve distinct endosome
populations . . . . . . . . . . . . . . 689
R. J. Garippa and
T. W. Judge and
D. E. James and
T. E. McGraw The amino terminus of GLUT4 functions as
an internalization motif but not an
intracellular retention signal when
substituted for the transferrin receptor
cytoplasmic domain . . . . . . . . . . . 705
M. H. Cardone and
B. L. Smith and
W. Song and
D. Mochly-Rosen and
K. E. Mostov Phorbol myristate acetate-mediated
stimulation of transcytosis and apical
recycling in MDCK cells . . . . . . . . 717
L. Hinck and
W. J. Nelson and
J. Papkoff Wnt-1 modulates cell--cell adhesion in
mammalian cells by stabilizing
beta-catenin binding to the cell
adhesion protein cadherin . . . . . . . 729
C. Brancolini and
C. Schneider Phosphorylation of the growth
arrest-specific protein Gas2 is coupled
to actin rearrangements during Go $\to$
G1 transition in NIH 3T3 cells . . . . . 743
K. Takenaga and
Y. Nakamura and
S. Sakiyama and
Y. Hasegawa and
K. Sato and
H. Endo Binding of pEL98 protein, an
S100-related calcium-binding protein, to
nonmuscle tropomyosin . . . . . . . . . 757
B. L. Goode and
S. C. Feinstein Identification of a novel microtubule
binding and assembly domain in the
developmentally regulated inter-repeat
region of tau . . . . . . . . . . . . . 769
R. Balczon and
L. Bao and
W. E. Zimmer PCM-1, A 228-kD centrosome autoantigen
with a distinct cell cycle distribution 783
M. A. Sanders and
J. L. Salisbury Centrin plays an essential role in
microtubule severing during flagellar
excision in \bionameChlamydomonas
reinhardtii . . . . . . . . . . . . . . 795
L. M. Quarmby and
H. C. Hartzell Two distinct, calcium-mediated, signal
transduction pathways can trigger
deflagellation in \bionameChlamydomonas
reinhardtii . . . . . . . . . . . . . . 807
D. R. Zimmermann and
M. T. Dours-Zimmermann and
M. Schubert and
L. Bruckner-Tuderman Versican is expressed in the
proliferating zone in the epidermis and
in association with the elastic network
of the dermis . . . . . . . . . . . . . 817
H. Li and
S. K. Choudhary and
D. J. Milner and
M. I. Munir and
I. R. Kuisk and
Y. Capetanaki Inhibition of desmin expression blocks
myoblast fusion and interferes with the
myogenic regulators MyoD and myogenin 827
W. J. Betz and
A. W. Henkel Okadaic acid disrupts clusters of
synaptic vesicles in frog motor nerve
terminals . . . . . . . . . . . . . . . 843
H. Zhang and
S. D. Apfelroth and
W. Hu and
E. C. Davis and
C. Sanguineti and
J. Bonadio and
R. P. Mecham and
F. Ramirez Structure and expression of fibrillin-2,
a novel microfibrillar component
preferentially located in elastic
matrices . . . . . . . . . . . . . . . . 855
K. Li and
C. S. Smagula and
W. J. Parsons and
J. A. Richardson and
M. Gonzalez and
H. K. Hagler and
R. S. Williams Subcellular partitioning of MRP RNA
assessed by ultrastructural and
biochemical analysis . . . . . . . . . . 871
S. Hara-Kuge and
O. Kuge and
L. Orci and
M. Amherdt and
M. Ravazzola and
F. T. Wieland and
J. E. Rothman En bloc incorporation of coatomer
subunits during the assembly of
COP-coated vesicles . . . . . . . . . . 883
M. C. Gautier and
N. Garreau de Loubresse and
L. Madeddu and
L. Sperling Evidence for defects in membrane traffic
in Paramecium secretory mutants unable
to produce functional storage granules 893
M. Baba and
K. Takeshige and
N. Baba and
Y. Ohsumi Ultrastructural analysis of the
autophagic process in yeast: detection
of autophagosomes and their
characterization . . . . . . . . . . . . 903
M. T. McCammon and
J. A. McNew and
P. J. Willy and
J. M. Goodman An internal region of the peroxisomal
membrane protein PMP47 is essential for
sorting to peroxisomes . . . . . . . . . 915
Y. Shi and
B. Veit and
S. Baekkeskov Amino acid residues 24--31 but not
palmitoylation of cysteines 30 and 45
are required for membrane anchoring of
glutamic acid decarboxylase, GAD65 . . . 927
K. Mensa-Wilmot and
J. H. LeBowitz and
K. P. Chang and
A. al-Qahtani and
B. S. McGwire and
S. Tucker and
J. C. Morris A glycosylphosphatidylinositol
(GPI)-negative phenotype produced in
Leishmania major by GPI phospholipase C
from Trypanosoma brucei: topography of
two GPI pathways . . . . . . . . . . . . 935
L. A. Jesaitis and
D. A. Goodenough Molecular characterization and tissue
distribution of ZO-2, a tight junction
protein homologous to ZO-1 and the
\bionameDrosophila discs-large tumor
suppressor protein . . . . . . . . . . . 949
K. M. Trybus and
G. S. Waller and
T. A. Chatman Coupling of ATPase activity and motility
in smooth muscle myosin is mediated by
the regulatory light chain . . . . . . . 963
K. A. Giuliano and
D. L. Taylor Fluorescent actin analogs with a high
affinity for profilin in vitro exhibit
an enhanced gradient of assembly in
living cells . . . . . . . . . . . . . . 971
A. Lieuvin and
J. C. Labbé and
M. Dorée and
D. Job Intrinsic microtubule stability in
interphase cells . . . . . . . . . . . . 985
C. M. Kielty and
C. A. Shuttleworth Abnormal fibrillin assembly by dermal
fibroblasts from two patients with
Marfan syndrome . . . . . . . . . . . . 997
J. Y. Wen and
C. M. Morshead and
D. van der Kooy Satellite cell proliferation in the
adult rat trigeminal ganglion results
from the release of a mitogenic protein
from explanted sensory neurons . . . . . 1005
W. E. Pierceall and
K. R. Cho and
R. H. Getzenberg and
M. A. Reale and
L. Hedrick and
B. Vogelstein and
E. R. Fearon NIH3T3 cells expressing the deleted in
colorectal cancer tumor suppressor gene
product stimulate neurite outgrowth in
rat PC12 pheochromocytoma cells . . . . 1017
E. J. Williams and
F. S. Walsh and
P. Doherty Tyrosine kinase inhibitors can
differentially inhibit
integrin-dependent and CAM-stimulated
neurite outgrowth . . . . . . . . . . . 1029
S. Malek-Hedayat and
L. H. Rome Expression of a beta $1$-related
integrin by oligodendroglia in primary
culture: evidence for a functional role
in myelination . . . . . . . . . . . . . 1039
T. E. O'Toole and
Y. Katagiri and
R. J. Faull and
K. Peter and
R. Tamura and
V. Quaranta and
J. C. Loftus and
S. J. Shattil and
M. H. Ginsberg Integrin cytoplasmic domains mediate
inside-out signal transduction . . . . . 1047
Y. van Kooyk and
P. Weder and
K. Heije and
C. G. Figdor Extracellular Ca$^{2+}$ modulates
leukocyte function-associated antigen-1
cell surface distribution on T
lymphocytes and consequently affects
cell adhesion . . . . . . . . . . . . . 1061
R. Schreiner and
E. Schnabel and
F. Wieland Novel N-glycosylation in eukaryotes:
laminin contains the linkage unit
beta-glucosylasparagine . . . . . . . . 1071
M. L. Matter and
G. W. Laurie A novel laminin E8 cell adhesion site
required for lung alveolar formation in
vitro . . . . . . . . . . . . . . . . . 1083
P. Reponen and
C. Sahlberg and
C. Munaut and
I. Thesleff and
K. Tryggvason High expression of 92-kD type IV
collagenase (gelatinase B) in the
osteoclast lineage during mouse
development . . . . . . . . . . . . . . 1091
R. A. Horowitz and
D. A. Agard and
J. W. Sedat and
C. L. Woodcock The three-dimensional architecture of
chromatin in situ: electron tomography
reveals fibers composed of a
continuously variable zig-zag
nucleosomal ribbon . . . . . . . . . . . 1
C. L. Woodcock Chromatin fibers observed in situ in
frozen hydrated sections. Native fiber
diameter is not correlated with
nucleosome repeat length . . . . . . . . 11
N. C. Hogan and
K. L. Traverse and
D. E. Sullivan and
M. L. Pardue The nucleus-limited Hsr-omega-n
transcript is a polyadenylated RNA with
a regulated intranuclear turnover . . . 21
R. W. Wozniak and
G. Blobel and
M. P. Rout POM152 is an integral protein of the
pore membrane domain of the yeast
nuclear envelope . . . . . . . . . . . . 31
J. Hayashi and
M. Takemitsu and
Y. Goto and
I. Nonaka Human mitochondria and mitochondrial
genome function as a single dynamic
cellular unit . . . . . . . . . . . . . 43
O. Kuge and
C. Dascher and
L. Orci and
T. Rowe and
M. Amherdt and
H. Plutner and
M. Ravazzola and
G. Tanigawa and
J. E. Rothman and
W. E. Balch Sar1 promotes vesicle budding from the
endoplasmic reticulum but not Golgi
compartments . . . . . . . . . . . . . . 51
G. Apodaca and
L. A. Katz and
K. E. Mostov Receptor-mediated transcytosis of IgA in
MDCK cells is via apical recycling
endosomes . . . . . . . . . . . . . . . 67
N. Ghinea and
T. V. Mai and
M. T. Groyer-Picard and
E. Milgrom How protein hormones reach their target
cells. Receptor-mediated transcytosis of
hCG through endothelial cells . . . . . 87
J. R. Lingappa and
R. L. Martin and
M. L. Wong and
D. Ganem and
W. J. Welch and
V. R. Lingappa A eukaryotic cytosolic chaperonin is
associated with a high molecular weight
intermediate in the assembly of
hepatitis B virus capsid, a multimeric
particle . . . . . . . . . . . . . . . . 99
M. C. Lopez and
J. M. Nicaud and
H. B. Skinner and
C. Vergnolle and
J. C. Kader and
V. A. Bankaitis and
C. Gaillardin A
phosphatidylinositol/phosphatidylcholine
transfer protein is required for
differentiation of the dimorphic yeast
Yarrowia lipolytica from the yeast to
the mycelial form . . . . . . . . . . . 113
J. Garrigues and
J. Anderson and
K. E. Hellström and
I. Hellström Anti-tumor antibody BR96 blocks cell
migration and binds to a lysosomal
membrane glycoprotein on cell surface
microspikes and ruffled membranes . . . 129
J. N. McMillan and
K. Tatchell The JNM1 gene in the yeast
\bionameSaccharomyces cerevisiae is
required for nuclear migration and
spindle orientation during the mitotic
cell cycle . . . . . . . . . . . . . . . 143
O. Skalli and
J. C. Jones and
R. Gagescu and
R. D. Goldman IFAP 300 is common to desmosomes and
hemidesmosomes and is a possible linker
of intermediate filaments to these
junctions . . . . . . . . . . . . . . . 159
J. Yu and
J. H. Lin and
X. R. Wu and
T. T. Sun Uroplakins Ia and Ib, two major
differentiation products of bladder
epithelium, belong to a family of four
transmembrane domain (4TM) proteins . . 171
L. Anglister and
B. Haesaert and
U. J. McMahan Globular and asymmetric
acetylcholinesterase in the synaptic
basal lamina of skeletal muscle . . . . 183
A. C. Bayly and
R. A. Roberts and
C. Dive Suppression of liver cell apoptosis in
vitro by the non-genotoxic
hepatocarcinogen and peroxisome
proliferator nafenopin . . . . . . . . . 197
P. Rousselle and
M. Aumailley Kalinin is more efficient than laminin
in promoting adhesion of primary
keratinocytes and some other epithelial
cells and has a different requirement
for integrin receptors . . . . . . . . . 205
R. H. Vonderheide and
T. F. Tedder and
T. A. Springer and
D. E. Staunton Residues within a conserved amino acid
motif of domains 1 and 4 of VCAM-1 are
required for binding to VLA-4 . . . . . 215
C. Nuoffer and
H. W. Davidson and
J. Matteson and
J. Meinkoth and
W. E. Balch A GDP-bound of rab1 inhibits protein
export from the endoplasmic reticulum
and transport between Golgi compartments 225
S. N. Pind and
C. Nuoffer and
J. M. McCaffery and
H. Plutner and
H. W. Davidson and
M. G. Farquhar and
W. E. Balch Rab1 and Ca$^{2+}$ are required for the
fusion of carrier vesicles mediating
endoplasmic reticulum to Golgi transport 239
S. Ponnambalam and
C. Rabouille and
J. P. Luzio and
T. Nilsson and
G. Warren The TGN38 glycoprotein contains two
non-overlapping signals that mediate
localization to the trans-Golgi network 253
T. Misteli and
G. Warren COP-coated vesicles are involved in the
mitotic fragmentation of Golgi stacks in
a cell-free system . . . . . . . . . . . 269
B. Singer-Krüger and
H. Stenmark and
A. Düsterhöft and
P. Philippsen and
J. S. Yoo and
D. Gallwitz and
M. Zerial Role of three rab5-like GTPases, Ypt51p,
Ypt52p, and Ypt53p, in the endocytic and
vacuolar protein sorting pathways of
yeast . . . . . . . . . . . . . . . . . 283
R. Y. Hampton and
J. Rine Regulated degradation of HMG--CoA
reductase, an integral membrane protein
of the endoplasmic reticulum, in yeast 299
T. Crepaldi and
A. L. Pollack and
M. Prat and
A. Zborek and
K. Mostov and
P. M. Comoglio Targeting of the SF/HGF receptor to the
basolateral domain of polarized
epithelial cells . . . . . . . . . . . . 313
Y. D. Stierhof and
T. Ilg and
D. G. Russell and
H. Hohenberg and
P. Overath Characterization of polymer release from
the flagellar pocket of Leishmania
mexicana promastigotes . . . . . . . . . 321
P. Moran and
I. W. Caras Requirements for
glycosylphosphatidylinositol attachment
are similar but not identical in
mammalian cells and parasitic protozoa 333
C. C. Gregorio and
E. A. Repasky and
V. M. Fowler and
J. D. Black Dynamic properties of ankyrin in T
lymphocytes: colocalization with
spectrin and protein kinase C beta . . . 345
K. S. Warren and
J. L. Lin and
D. D. Wamboldt and
J. J. Lin Overexpression of human fibroblast
caldesmon fragment containing actin-,
Ca++/calmodulin-, and
tropomyosin-binding domains stabilizes
endogenous tropomyosin and
microfilaments . . . . . . . . . . . . . 359
K. Cant and
B. A. Knowles and
M. S. Mooseker and
L. Cooley Drosophila singed, a fascin homolog, is
required for actin bundle formation
during oogenesis and bristle extension 369
J. Mulholland and
D. Preuss and
A. Moon and
A. Wong and
D. Drubin and
D. Botstein Ultrastructure of the yeast actin
cytoskeleton and its association with
the plasma membrane . . . . . . . . . . 381
T. Koji and
M. Chedid and
J. S. Rubin and
O. D. Slayden and
K. G. Csaky and
S. A. Aaronson and
R. M. Brenner Progesterone-dependent expression of
keratinocyte growth factor mRNA in
stromal cells of the primate
endometrium: keratinocyte growth factor
as a progestomedin . . . . . . . . . . . 393
R. C. Bates and
A. Buret and
D. F. van Helden and
M. A. Horton and
G. F. Burns Apoptosis induced by inhibition of
intercellular contact . . . . . . . . . 403
C. Kioussi and
P. Gruss Differential induction of Pax genes by
NGF and BDNF in cerebellar primary
cultures . . . . . . . . . . . . . . . . 417
J. L. Saffell and
F. S. Walsh and
P. Doherty Expression of NCAM containing VASE in
neurons can account for a developmental
loss in their neurite outgrowth response
to NCAM in a cellular substratum . . . . 427
S. V. Litvinov and
M. P. Velders and
H. A. Bakker and
G. J. Fleuren and
S. O. Warnaar Ep-CAM: a human epithelial antigen is a
homophilic cell--cell adhesion molecule 437
R. Pasqualini and
M. E. Hemler Contrasting roles for integrin beta 1
and beta 5 cytoplasmic domains in
subcellular localization, cell
proliferation, and cell migration . . . 447
J. Kahn and
R. H. Ingraham and
F. Shirley and
G. I. Migaki and
T. K. Kishimoto Membrane proximal cleavage of
L-selectin: identification of the
cleavage site and a 6-kD transmembrane
peptide fragment of L-selectin . . . . . 461
M. Lenter and
A. Levinovitz and
S. Isenmann and
D. Vestweber Monospecific and common glycoprotein
ligands for E- and P-selectin on myeloid
cells . . . . . . . . . . . . . . . . . 471
K. Matsumoto and
Y. Saga and
T. Ikemura and
T. Sakakura and
R. Chiquet-Ehrismann The distribution of tenascin--X is
distinct and often reciprocal to that of
tenascin--C . . . . . . . . . . . . . . 483
D. M. Jaworski and
G. M. Kelly and
S. Hockfield BEHAB, a new member of the proteoglycan
tandem repeat family of
hyaluronan-binding proteins that is
restricted to the brain . . . . . . . . 495
E. Fuchs Intermediate filaments and disease:
mutations that cripple cell strength . . 511
V. Guacci and
E. Hogan and
D. Koshland Chromosome condensation and sister
chromatid pairing in budding yeast . . . 517
J. Tomkiel and
C. A. Cooke and
H. Saitoh and
R. L. Bernat and
W. C. Earnshaw CENP-C is required for maintaining
proper kinetochore size and for a timely
transition to anaphase . . . . . . . . . 531
E. J. Adam and
S. A. Adam Identification of cytosolic factors
required for nuclear location
sequence-mediated binding to the nuclear
envelope . . . . . . . . . . . . . . . . 547
B. S. Wilson and
C. Nuoffer and
J. L. Meinkoth and
M. McCaffery and
J. R. Feramisco and
W. E. Balch and
M. G. Farquhar A Rab1 mutant affecting guanine
nucleotide exchange promotes disassembly
of the Golgi apparatus . . . . . . . . . 557
M. A. Riederer and
T. Soldati and
A. D. Shapiro and
J. Lin and
S. R. Pfeffer Lysosome biogenesis requires Rab9
function and receptor recycling from
endosomes to the trans-Golgi network . . 573
E. Weber and
G. Berta and
A. Tousson and
P. St John and
M. W. Green and
U. Gopalokrishnan and
T. Jilling and
E. J. Sorscher and
T. S. Elton and
D. R. Abrahamson Expression and polarized targeting of a
rab3 isoform in epithelial cells . . . . 583
Y. Qiu and
X. Xu and
A. Wandinger-Ness and
D. P. Dalke and
S. K. Pierce Separation of subcellular compartments
containing distinct functional forms of
MHC class II . . . . . . . . . . . . . . 595
M. C. Stella and
H. Schauerte and
K. L. Straub and
M. Leptin Identification of secreted and cytosolic
gelsolin in \bionameDrosophila . . . . . 607
Y. Zhang and
W. J. Snell Flagellar adhesion-dependent regulation
of \bionameChlamydomonas adenylyl
cyclase in vitro: a possible role for
protein kinases in sexual signaling . . 617
J. Lukas and
H. Müller and
J. Bartkova and
D. Spitkovsky and
A. A. Kjerulff and
P. Jansen-Dürr and
M. Strauss and
J. Bartek DNA tumor virus oncoproteins and
retinoblastoma gene mutations share the
ability to relieve the cell's
requirement for cyclin D1 function in G1 625
S. C. Ley and
M. Marsh and
C. R. Bebbington and
K. Proudfoot and
P. Jordan Distinct intracellular localization of
Lck and Fyn protein tyrosine kinases in
human T lymphocytes . . . . . . . . . . 639
A. D. Whetton and
C. M. Heyworth and
S. E. Nicholls and
C. A. Evans and
J. M. Lord and
T. M. Dexter and
P. J. Owen-Lynch Cytokine-mediated protein kinase C
activation is a signal for lineage
determination in bipotential granulocyte
macrophage colony-forming cells . . . . 651
B. G. Wallace Staurosporine inhibits agrin-induced
acetylcholine receptor phosphorylation
and aggregation . . . . . . . . . . . . 661
D. R. Friedlander and
P. Milev and
L. Karthikeyan and
R. K. Margolis and
R. U. Margolis and
M. Grumet The neuronal chondroitin sulfate
proteoglycan neurocan binds to the
neural cell adhesion molecules
Ng-CAM\slash L1\slash NILE and N-CAM,
and inhibits neuronal adhesion and
neurite outgrowth . . . . . . . . . . . 669
C. J. Sympson and
R. S. Talhouk and
C. M. Alexander and
J. R. Chin and
S. M. Clift and
M. J. Bissell and
Z. Werb Targeted expression of stromelysin-1 in
mammary gland provides evidence for a
role of proteinases in branching
morphogenesis and the requirement for an
intact basement membrane for
tissue-specific gene expression . . . . 681
D. J. Liska and
M. J. Reed and
E. H. Sage and
P. Bornstein Cell-specific expression of alpha 1(I)
collagen-hGH minigenes in transgenic
mice . . . . . . . . . . . . . . . . . . 695
S. Kornbluth and
M. Dasso and
J. Newport Evidence for a dual role for TC4 protein
in regulating nuclear structure and cell
cycle progression . . . . . . . . . . . 705
W. Nickel and
L. A. Huber and
R. A. Kahn and
N. Kipper and
A. Barthel and
D. Fasshauer and
H. D. Söling ADP ribosylation factor and a 14-kD
polypeptide are associated with heparan
sulfate-carrying post-trans-Golgi
network secretory vesicles in rat
hepatocytes . . . . . . . . . . . . . . 721
L. Saucan and
G. E. Palade Membrane and secretory proteins are
transported from the Golgi complex to
the sinusoidal plasmalemma of
hepatocytes by distinct vesicular
carriers . . . . . . . . . . . . . . . . 733
Y. N. Wu and
M. Gadina and
J. H. Tao-Cheng and
R. J. Youle Retinoic acid disrupts the Golgi
apparatus and increases the cytosolic
routing of specific protein toxins . . . 743
A. Motley and
E. Hettema and
B. Distel and
H. Tabak Differential protein import deficiencies
in human peroxisome assembly disorders 755
O. C. Martin and
R. E. Pagano Internalization and sorting of a
fluorescent analogue of glucosylceramide
to the Golgi apparatus of human skin
fibroblasts: utilization of endocytic
and nonendocytic transport mechanisms 769
D. Illinger and
J. G. Kuhry The kinetic aspects of intracellular
fluorescence labeling with TMA--DPH
support the maturation model for
endocytosis in L929 cells . . . . . . . 783
J. L. Thomas and
D. Holowka and
B. Baird and
W. W. Webb Large-scale co-aggregation of
fluorescent lipid probes with cell
surface proteins . . . . . . . . . . . . 795
W. R. Skach and
L. B. Shi and
M. C. Calayag and
A. Frigeri and
V. R. Lingappa and
A. S. Verkman Biogenesis and transmembrane topology of
the CHIP28 water channel at the
endoplasmic reticulum . . . . . . . . . 803
K. Ohlendieck and
J. S. Partin and
W. J. Lennarz The biologically active form of the sea
urchin egg receptor for sperm is a
disulfide-bonded homo-multimer . . . . . 817
S. H. Lillie and
S. S. Brown Immunofluorescence localization of the
unconventional myosin, Myo2p, and the
putative kinesin-related protein, Smy1p,
to the same regions of polarized growth
in \bionameSaccharomyces cerevisiae . . 825
S. Biggins and
M. D. Rose Direct interaction between yeast spindle
pole body components: Kar1p is required
for Cdc31p localization to the spindle
pole body . . . . . . . . . . . . . . . 843
M. A. Osborne and
G. Schlenstedt and
T. Jinks and
P. A. Silver Nuf2, a spindle pole body-associated
protein required for nuclear division in
yeast . . . . . . . . . . . . . . . . . 853
A. Cheng and
T. Le and
M. Palacios and
L. H. Bookbinder and
P. M. Wassarman and
F. Suzuki and
J. D. Bleil Sperm-egg recognition in the mouse:
characterization of sp56, a sperm
protein having specific affinity for ZP3 867
T. W. White and
R. Bruzzone and
S. Wolfram and
D. L. Paul and
D. A. Goodenough Selective interactions among the
multiple connexin proteins expressed in
the vertebrate lens: the second
extracellular domain is a determinant of
compatibility between connexins . . . . 879
P. Caroni and
C. Schneider and
M. C. Kiefer and
J. Zapf Role of muscle insulin-like growth
factors in nerve sprouting: suppression
of terminal sprouting in paralyzed
muscle by IGF-binding protein 4 . . . . 893
L. Shum and
S. A. Reeves and
A. C. Kuo and
E. S. Fromer and
R. Derynck Association of the transmembrane
TGF-alpha precursor with a protein
kinase complex . . . . . . . . . . . . . 903
E. J. Battegay and
J. Rupp and
L. Iruela-Arispe and
E. H. Sage and
M. Pech PDGF-BB modulates endothelial
proliferation and angiogenesis in vitro
via PDGF beta-receptors . . . . . . . . 917
T. F. Lane and
M. L. Iruela-Arispe and
R. S. Johnson and
E. H. Sage SPARC is a source of copper-binding
peptides that stimulate angiogenesis . . 929
A. Pierres and
O. Tissot and
B. Malissen and
P. Bongrand Dynamic adhesion of CD8-positive cells
to antibody-coated surfaces: the initial
step is independent of microfilaments
and intracellular domains of
cell-binding molecules . . . . . . . . . 945
S. R. Wente and
G. Blobel NUP145 encodes a novel yeast
glycine-leucine-phenylalanine-glycine
(GLFG) nucleoporin required for nuclear
envelope structure . . . . . . . . . . . 955
U. Fischer and
J. Heinrich and
K. van Zee and
E. Fanning and
R. Lührmann Nuclear transport of U1 snRNP in somatic
cells: differences in signal requirement
compared with \bionameXenopus laevis
oocytes . . . . . . . . . . . . . . . . 971
F. H. Simons and
G. J. Pruijn and
W. J. van Venrooij Analysis of the intracellular
localization and assembly of Ro
ribonucleoprotein particles by
microinjection into \bionameXenopus
laevis oocytes . . . . . . . . . . . . . 981
Y. Gao and
R. Melki and
P. D. Walden and
S. A. Lewis and
C. Ampe and
H. Rommelaere and
J. Vandekerckhove and
N. J. Cowan A novel cochaperonin that modulates the
ATPase activity of cytoplasmic
chaperonin . . . . . . . . . . . . . . . 989
R. M. Rios and
A. M. Tassin and
C. Celati and
C. Antony and
M. C. Boissier and
J. C. Homberg and
M. Bornens A peripheral protein associated with the
cis-Golgi network redistributes in the
intermediate compartment upon brefeldin
A treatment . . . . . . . . . . . . . . 997
T. Galli and
T. Chilcote and
O. Mundigl and
T. Binz and
H. Niemann and
P. De Camilli Tetanus toxin-mediated cleavage of
cellubrevin impairs exocytosis of
transferrin receptor-containing vesicles
in CHO cells . . . . . . . . . . . . . . 1015
S. W. Pimplikar and
E. Ikonen and
K. Simons Basolateral protein transport in
streptolysin O-permeabilized MDCK cells 1025
P. A. Walton and
M. Wendland and
S. Subramani and
R. A. Rachubinski and
W. J. Welch Involvement of 70-kD heat-shock proteins
in peroxisomal import . . . . . . . . . 1037
F. Fagotto and
F. R. Maxfield Yolk platelets in \bionameXenopus
oocytes maintain an acidic internal pH
which may be essential for sodium
accumulation . . . . . . . . . . . . . . 1047
S. C. Dahl and
R. W. Geib and
M. T. Fox and
M. Edidin and
D. Branton Rapid capping in
alpha-spectrin-deficient MEL cells from
mice afflicted with hereditary hemolytic
anemia . . . . . . . . . . . . . . . . . 1057
S. H. Lo and
P. A. Janmey and
J. H. Hartwig and
L. B. Chen Interactions of tensin with actin and
identification of its three distinct
actin-binding domains . . . . . . . . . 1067
W. Yamochi and
K. Tanaka and
H. Nonaka and
A. Maeda and
T. Musha and
Y. Takai Growth site localization of Rho1 small
GTP-binding protein and its involvement
in bud formation in
\bionameSaccharomyces cerevisiae . . . . 1077
S. Kondo and
R. Sato-Yoshitake and
Y. Noda and
H. Aizawa and
T. Nakata and
Y. Matsuura and
N. Hirokawa KIF3A is a new microtubule-based
anterograde motor in the nerve axon . . 1095
G. Piperno and
K. Mead and
M. LeDizet and
A. Moscatelli Mutations in the ``dynein regulatory
complex'' alter the ATP-insensitive
binding sites for inner arm dyneins in
\bionameChlamydomonas axonemes . . . . . 1109
C. Beck and
R. Uhl On the localization of voltage-sensitive
calcium channels in the flagella of
\bionameChlamydomonas reinhardtii . . . 1119
S. L. Tamm and
M. Terasaki Visualization of calcium transients
controlling orientation of ciliary beat 1127
M. Crescenzi and
D. H. Crouch and
F. Tat\`o Transformation by myc prevents fusion
but not biochemical differentiation of
C2C12 myoblasts: mechanisms of
phenotypic correction in mixed culture
with normal cells . . . . . . . . . . . 1137
K. R. Matthews and
K. Gull Evidence for an interplay between cell
cycle progression and the initiation of
differentiation between life cycle forms
of African trypanosomes . . . . . . . . 1147
Y. Lin and
K. Mahan and
W. F. Lathrop and
D. G. Myles and
P. Primakoff A hyaluronidase activity of the sperm
plasma membrane protein PH-20 enables
sperm to penetrate the cumulus cell
layer surrounding the egg . . . . . . . 1157
A. M. Romanic and
J. A. Madri The induction of 72-kD gelatinase in T
cells upon adhesion to endothelial cells
is VCAM-1 dependent . . . . . . . . . . 1165
J. D. San Antonio and
A. D. Lander and
M. J. Karnovsky and
H. S. Slayter Mapping the heparin-binding sites on
type I collagen monomers and fibrils . . 1179
J. Loidl and
F. Klein and
H. Scherthan Homologous pairing is reduced but not
abolished in asynaptic mutants of yeast 1191
R. D. Moir and
M. Montag-Lowy and
R. D. Goldman Dynamic properties of nuclear lamins:
lamin B is associated with sites of DNA
replication . . . . . . . . . . . . . . 1201
Q. Guo and
E. Vasile and
M. Krieger Disruptions in Golgi structure and
membrane traffic in a conditional lethal
mammalian cell mutant are corrected by
epsilon--COP . . . . . . . . . . . . . . 1213
J. M. Riberdy and
R. R. Avva and
H. J. Geuze and
P. Cresswell Transport and intracellular distribution
of MHC class II molecules and associated
invariant chain in normal and
antigen-processing mutant cell lines . . 1225
S. L. Shyng and
J. E. Heuser and
D. A. Harris A glycolipid-anchored prion protein is
endocytosed via clathrin-coated pits . . 1239
Y. Sako and
A. Kusumi Compartmentalized structure of the
plasma membrane for receptor movements
as revealed by a nanometer-level motion
analysis . . . . . . . . . . . . . . . . 1251
C. R. Hopkins and
A. Gibson and
M. Shipman and
D. K. Strickland and
I. S. Trowbridge In migrating fibroblasts, recycling
receptors are concentrated in narrow
tubules in the pericentriolar area, and
then routed to the plasma membrane of
the leading lamella . . . . . . . . . . 1265
T. A. Rando and
H. M. Blau Primary mouse myoblast purification,
characterization, and transplantation
for cell-mediated gene therapy . . . . . 1275
M. K. Balasubramanian and
B. R. Hirani and
J. D. Burke and
K. L. Gould The \bionameSchizosaccharomyces pombe
cdc3+ gene encodes a profilin essential
for cytokinesis . . . . . . . . . . . . 1289
K. D. Brown and
R. M. Coulson and
T. J. Yen and
D. W. Cleveland Cyclin-like accumulation and loss of the
putative kinetochore motor CENP--E
results from coupling continuous
synthesis with specific degradation at
the end of mitosis . . . . . . . . . . . 1303
M. Bernstein and
P. L. Beech and
S. G. Katz and
J. L. Rosenbaum A new kinesin-like protein (Klp1)
localized to a single microtubule of the
\bionameChlamydomonas flagellum . . . . 1313
L. Hinck and
I. S. Näthke and
J. Papkoff and
W. J. Nelson Dynamics of cadherin/catenin complex
formation: novel protein interactions
and pathways of complex assembly . . . . 1327
I. S. Näthke and
L. Hinck and
J. R. Swedlow and
J. Papkoff and
W. J. Nelson Defining interactions and distributions
of cadherin and catenin complexes in
polarized epithelial cells . . . . . . . 1341
D. Berndorff and
R. Gessner and
B. Kreft and
N. Schnoy and
A. M. Lajous-Petter and
N. Loch and
W. Reutter and
M. Hortsch and
R. Tauber Liver-intestine cadherin: molecular
cloning and characterization of a novel
Ca(2+)-dependent cell adhesion molecule
expressed in liver and intestine . . . . 1353
K. Takeuchi and
N. Sato and
H. Kasahara and
N. Funayama and
A. Nagafuchi and
S. Yonemura and
S. Tsukita and
S. Tsukita Perturbation of cell adhesion and
microvilli formation by antisense
oligonucleotides to ERM family members 1371
T. Iwaki and
A. Iwaki and
J. Tateishi and
J. E. Goldman Sense and antisense modification of
glial alpha B-crystallin production
results in alterations of stress fiber
formation and thermoresistance . . . . . 1385
M. E. Renz and
H. H. Chiu and
S. Jones and
J. Fox and
K. J. Kim and
L. G. Presta and
S. Fong Structural requirements for adhesion of
soluble recombinant murine vascular cell
adhesion molecule-1 to alpha 4 beta 1 1395
M. J. Zhou and
E. J. Brown CR3 (Mac-1, alpha M beta 2, CD11b/CD18)
and Fc gamma RIII cooperate in
generation of a neutrophil respiratory
burst: requirement for Fc gamma RIII and
tyrosine phosphorylation . . . . . . . . 1407
F. W. Luscinskas and
G. S. Kansas and
H. Ding and
P. Pizcueta and
B. E. Schleiffenbaum and
T. F. Tedder and
M. A. Gimbrone Monocyte rolling, arrest and spreading
on IL-4-activated vascular endothelium
under flow is mediated via sequential
action of L-selectin, beta
$1$-integrins, and beta $2$-integrins 1417
W. Hoch and
J. T. Campanelli and
R. H. Scheller Agrin-induced clustering of
acetylcholine receptors: a cytoskeletal
link . . . . . . . . . . . . . . . . . . 1
R. A. Heller and
M. Krönke Tumor necrosis factor receptor-mediated
signaling pathways . . . . . . . . . . . 5
J. A. Ferreira and
M. Carmo-Fonseca and
A. I. Lamond Differential interaction of splicing
snRNPs with coiled bodies and
interchromatin granules during mitosis
and assembly of daughter cell nuclei . . 11
A. Schweizer and
J. Rohrer and
H. P. Hauri and
S. Kornfeld Retention of p63 in an ER--Golgi
intermediate compartment depends on the
presence of all three of its domains and
on its ability to form oligomers . . . . 25
C. Hammond and
A. Helenius Quality control in the secretory
pathway: retention of a misfolded viral
membrane glycoprotein involves cycling
between the ER, intermediate
compartment, and Golgi apparatus . . . . 41
K. Sandvig and
M. Ryd and
O. Garred and
E. Schweda and
P. K. Holm and
B. van Deurs Retrograde transport from the Golgi
complex to the ER of both Shiga toxin
and the nontoxic Shiga B-fragment is
regulated by butyric acid and cAMP . . . 53
J. P. Yan and
M. E. Colon and
L. A. Beebe and
P. Melançon Isolation and characterization of mutant
CHO cell lines with compartment-specific
resistance to brefeldin A . . . . . . . 65
R. Kuliawat and
P. Arvan Distinct molecular mechanisms for
protein sorting within immature
secretory granules of pancreatic
beta-cells . . . . . . . . . . . . . . . 77
A. Haas and
B. Conradt and
W. Wickner G-protein ligands inhibit in vitro
reactions of vacuole inheritance . . . . 87
B. Conradt and
A. Haas and
W. Wickner Determination of four biochemically
distinct, sequential stages during
vacuole inheritance in vitro . . . . . . 99
M. P. Lisanti and
P. E. Scherer and
J. Vidugiriene and
Z. Tang and
A. Hermanowski-Vosatka and
Y. H. Tu and
R. F. Cook and
M. Sargiacomo Characterization of caveolin-rich
membrane domains isolated from an
endothelial-rich source: implications
for human disease . . . . . . . . . . . 111
W. J. Chang and
Y. S. Ying and
K. G. Rothberg and
N. M. Hooper and
A. J. Turner and
H. A. Gambliel and
J. De Gunzburg and
S. M. Mumby and
A. G. Gilman and
R. G. Anderson Purification and characterization of
smooth muscle cell caveolae . . . . . . 127
Y. I. Henis and
A. Moustakas and
H. Y. Lin and
H. F. Lodish The types II and III transforming growth
factor-beta receptors form
homo-oligomers . . . . . . . . . . . . . 139
K. M. Hager and
M. A. Pierce and
D. R. Moore and
E. M. Tytler and
J. D. Esko and
S. L. Hajduk Endocytosis of a cytotoxic human high
density lipoprotein results in
disruption of acidic intracellular
vesicles and subsequent killing of
African trypanosomes . . . . . . . . . . 155
T. L. Madden and
J. Herzfeld Crowding-induced organization of
cytoskeletal elements: II. Dissolution
of spontaneously formed filament bundles
by capping proteins . . . . . . . . . . 169
Z. Walther and
M. Vashishtha and
J. L. Hall The \bionameChlamydomonas FLA10 gene
encodes a novel kinesin-homologous
protein . . . . . . . . . . . . . . . . 175
G. Sluder and
F. J. Miller and
E. A. Thompson and
D. E. Wolf Feedback control of the
metaphase-anaphase transition in sea
urchin zygotes: role of maloriented
chromosomes . . . . . . . . . . . . . . 189
S. Clark-Maguire and
P. E. Mains Localization of the mei-1 gene product
of Caenorhaditis elegans, a
meiotic-specific spindle component . . . 199
I. Duluc and
J. N. Freund and
C. Leberquier and
M. Kedinger Fetal endoderm primarily holds the
temporal and positional information
required for mammalian intestinal
development . . . . . . . . . . . . . . 211
P. Nagy and
H. C. Bisgaard and
S. S. Thorgeirsson Expression of hepatic transcription
factors during liver development and
oval cell differentiation . . . . . . . 223
T. Kanda and
H. Yoshino and
T. Ariga and
M. Yamawaki and
R. K. Yu Glycosphingolipid antigens in cultured
bovine brain microvascular endothelial
cells: sulfoglucuronosyl paragloboside
as a target of monoclonal IgM in
demyelinative neuropathy [corrected] . . 235
O. Ayalon and
H. Sabanai and
M. G. Lampugnani and
E. Dejana and
B. Geiger Spatial and temporal relationships
between cadherins and PECAM-1 in
cell--cell junctions of human
endothelial cells . . . . . . . . . . . 247
N. Busso and
S. K. Masur and
D. Lazega and
S. Waxman and
L. Ossowski Induction of cell migration by
pro-urokinase binding to its receptor:
possible mechanism for signal
transduction in human epithelial cells 259
P. Sánchez-Aparicio and
C. Dominguez-Jiménez and
A. Garcia-Pardo Activation of the alpha 4 beta 1
integrin through the beta 1 subunit
induces recognition of the RGDS sequence
in fibronectin . . . . . . . . . . . . . 271
P. Matsudaira The fimbrin and alpha-actinin footprint
on actin . . . . . . . . . . . . . . . . 285
M. G. Gerdes and
K. C. Carter and
P. T. Moen and
J. B. Lawrence Dynamic changes in the higher-level
chromatin organization of specific
sequences revealed by in situ
hybridization to nuclear halos . . . . . 289
J. Höhfeld and
F. U. Hartl Role of the chaperonin cofactor Hsp10 in
protein folding and sorting in yeast
mitochondria . . . . . . . . . . . . . . 305
C. G. Odorizzi and
I. S. Trowbridge and
L. Xue and
C. R. Hopkins and
C. D. Davis and
J. F. Collawn Sorting signals in the MHC class II
invariant chain cytoplasmic tail and
transmembrane region determine
trafficking to an endocytic processing
compartment . . . . . . . . . . . . . . 317
M. Solimena and
R. Dirkx and
M. Radzynski and
O. Mundigl and
P. De Camilli A signal located within amino acids
1--27 of GAD65 is required for its
targeting to the Golgi complex region 331
T. Ruscetti and
J. A. Cardelli and
M. L. Niswonger and
T. J. O'Halloran Clathrin heavy chain functions in
sorting and secretion of lysosomal
enzymes in \bionameDictyostelium
discoideum . . . . . . . . . . . . . . . 343
A. M. Shenoy-Scaria and
D. J. Dietzen and
J. Kwong and
D. C. Link and
D. M. Lublin Cysteine3 of Src family protein tyrosine
kinase determines palmitoylation and
localization in caveolae . . . . . . . . 353
T. A. Smith and
B. D. Kohorn Mutations in a signal sequence for the
thylakoid membrane identify multiple
protein transport pathways and nuclear
suppressors . . . . . . . . . . . . . . 365
M. Bähler and
R. Kroschewski and
H. E. Stöffler and
T. Behrmann Rat myr 4 defines a novel subclass of
myosin I: identification, distribution,
localization, and mapping of
calmodulin-binding sites with
differential calcium sensitivity . . . . 375
S. Tsukita and
K. Oishi and
N. Sato and
J. Sagara and
A. Kawai and
S. Tsukita ERM family members as molecular linkers
between the cell surface glycoprotein
CD44 and actin-based cytoskeletons . . . 391
D. A. Schafer and
S. R. Gill and
J. A. Cooper and
J. E. Heuser and
T. A. Schroer Ultrastructural analysis of the dynactin
complex: an actin-related protein is a
component of a filament that resembles
F-actin . . . . . . . . . . . . . . . . 403
J. E. Honts and
T. S. Sandrock and
S. M. Brower and
J. L. O'Dell and
A. E. Adams Actin mutations that show suppression
with fimbrin mutations identify a likely
fimbrin-binding site on actin . . . . . 413
D. A. Holtzman and
K. F. Wertman and
D. G. Drubin Mapping actin surfaces required for
functional interactions in vivo . . . . 423
A. McGough and
M. Way and
D. DeRosier Determination of the
alpha-actinin-binding site on actin
filaments by cryoelectron microscopy and
image analysis . . . . . . . . . . . . . 433
R. B. Cary and
M. W. Klymkowsky Differential organization of desmin and
vimentin in muscle is due to differences
in their head domains . . . . . . . . . 445
Y. He and
F. Grinnell Stress relaxation of fibroblasts
activates a cyclic AMP signaling pathway 457
B. Dehouck and
M. P. Dehouck and
J. C. Fruchart and
R. Cecchelli Upregulation of the low density
lipoprotein receptor at the blood-brain
barrier: intercommunications between
brain capillary endothelial cells and
astrocytes . . . . . . . . . . . . . . . 465
N. Tavoloni and
H. Inoue and
H. Sabe and
H. Hanafusa v-src transformation of rat embryo
fibroblasts. Inefficient conversion to
anchorage-independent growth involves
heterogeneity of primary cultures . . . 475
W. Jung and
E. Castren and
M. Odenthal and
G. F. Vande Woude and
T. Ishii and
H. P. Dienes and
D. Lindholm and
P. Schirmacher Expression and functional interaction of
hepatocyte growth factor-scatter factor
and its receptor c-met in mammalian
brain . . . . . . . . . . . . . . . . . 485
H. Tseng and
H. Green Association of basonuclin with ability
of keratinocytes to multiply and with
absence of terminal differentiation . . 495
P. K. Legan and
K. K. Yue and
M. A. Chidgey and
J. L. Holton and
R. W. Wilkinson and
D. R. Garrod The bovine desmocollin family: a new
gene and expression patterns reflecting
epithelial cell proliferation and
differentiation . . . . . . . . . . . . 507
W. M. Brieher and
B. M. Gumbiner Regulation of C-cadherin function during
activin induced morphogenesis of
\bionameXenopus animal caps . . . . . . 519
R. C. Landis and
A. McDowall and
C. L. Holness and
A. J. Littler and
D. L. Simmons and
N. Hogg Involvement of the ``I'' domain of LFA-1
in selective binding to ligands ICAM-1
and ICAM-3 . . . . . . . . . . . . . . . 529
C. Y. Chung and
H. P. Erickson Cell surface annexin II is a high
affinity receptor for the alternatively
spliced segment of tenascin--C . . . . . 539
E. R. Sjoberg and
L. D. Powell and
A. Klein and
A. Varki Natural ligands of the B cell adhesion
molecule CD22 beta can be masked by
9-O-acetylation of sialic acids . . . . 549
A. Hinek and
M. Rabinovitch $ 67$-kD elastin-binding protein is a
protective ``companion'' of
extracellular insoluble elastin and
intracellular tropoelastin . . . . . . . 563
C. L. Hall and
C. Wang and
L. A. Lange and
E. A. Turley Hyaluronan and the hyaluronan receptor
RHAMM promote focal adhesion turnover
and transient tyrosine kinase activity 575
S. Dimitrov and
M. C. Dasso and
A. P. Wolffe Remodeling sperm chromatin in
\bionameXenopus laevis egg extracts: the
role of core histone phosphorylation and
linker histone B4 in chromatin assembly 591
N. Panté and
R. Bastos and
I. McMorrow and
B. Burke and
U. Aebi Interactions and three-dimensional
localization of a group of nuclear pore
complex proteins . . . . . . . . . . . . 603
K. D. Belanger and
M. A. Kenna and
S. Wei and
L. I. Davis Genetic and physical interactions
between Srp1p and nuclear pore complex
proteins Nup1p and Nup2p . . . . . . . . 619
M. L. Ferguson and
A. F. Torri and
D. Pérez-Morga and
D. C. Ward and
P. T. Englund Kinetoplast DNA replication: mechanistic
differences between Trypanosoma brucei
and Crithidia fasciculata . . . . . . . 631
D. R. Robinson and
K. Gull The configuration of DNA replication
sites within the Trypanosoma brucei
kinetoplast . . . . . . . . . . . . . . 641
T. Kadowaki and
S. Chen and
M. Hitomi and
E. Jacobs and
C. Kumagai and
S. Liang and
R. Schneiter and
D. Singleton and
J. Wisniewska and
A. M. Tartakoff Isolation and characterization of
\bionameSaccharomyces cerevisiae mRNA
transport-defective (mtr) mutants . . . 649
K. R. Fath and
G. M. Trimbur and
D. R. Burgess Molecular motors are differentially
distributed on Golgi membranes from
polarized epithelial cells . . . . . . . 661
S. H. Hansen and
J. E. Casanova Gs alpha stimulates transcytosis and
apical secretion in MDCK cells through
cAMP and protein kinase A . . . . . . . 677
R. M. Cripps and
K. D. Becker and
M. Mardahl and
W. A. Kronert and
D. Hodges and
S. I. Bernstein Transformation of \bionameDrosophila
melanogaster with the wild-type myosin
heavy-chain gene: rescue of mutant
phenotypes and analysis of defects
caused by overexpression . . . . . . . . 689
J. M. Metzger and
W. I. Lin and
L. C. Samuelson Transition in cardiac contractile
sensitivity to calcium during the in
vitro differentiation of mouse embryonic
stem cells . . . . . . . . . . . . . . . 701
S. Grabski and
X. G. Xie and
J. F. Holland and
M. Schindler Lipids trigger changes in the elasticity
of the cytoskeleton in plant cells: a
cell optical displacement assay for live
cell measurements . . . . . . . . . . . 713
K. Barkalow and
T. Hamasaki and
P. Satir Regulation of 22S dynein by a 29-kD
light chain . . . . . . . . . . . . . . 727
S. Takada and
R. Kamiya Functional reconstitution of
\bionameChlamydomonas outer dynein arms
from alpha-beta and gamma subunits:
requirement of a third factor . . . . . 737
M. L. Saxon and
X. Zhao and
J. D. Black Activation of protein kinase C isozymes
is associated with post-mitotic events
in intestinal epithelial cells in situ 747
M. J. Steinbeck and
W. H. Appel and
A. J. Verhoeven and
M. J. Karnovsky NADPH-oxidase expression and in situ
production of superoxide by osteoclasts
actively resorbing bone . . . . . . . . 765
M. Tamura and
M. Noda Identification of a DNA sequence
involved in osteoblast-specific gene
expression via interaction with
helix-loop-helix (HLH)-type
transcription factors . . . . . . . . . 773
A. Faissner and
A. Clement and
A. Lochter and
A. Streit and
C. Mandl and
M. Schachner Isolation of a neural chondroitin
sulfate proteoglycan with neurite
outgrowth promoting properties . . . . . 783
K. Jalink and
E. J. van Corven and
T. Hengeveld and
N. Morii and
S. Narumiya and
W. H. Moolenaar Inhibition of lysophosphatidate- and
thrombin-induced neurite retraction and
neuronal cell rounding by ADP
ribosylation of the small GTP-binding
protein Rho . . . . . . . . . . . . . . 801
C. A. Hansen and
A. G. Schroering and
D. J. Carey and
J. D. Robishaw Localization of a heterotrimeric G
protein gamma subunit to focal adhesions
and associated stress fibers . . . . . . 811
A. Bretscher and
B. Drees and
E. Harsay and
D. Schott and
T. Wang What are the basic functions of
microfilaments? Insights from studies in
budding yeast . . . . . . . . . . . . . 821
F. A. Oberhammer and
K. Hochegger and
G. Fröschl and
R. Tiefenbacher and
M. Pavelka Chromatin condensation during apoptosis
is accompanied by degradation of lamin
A+B, without enhanced activation of cdc2
kinase . . . . . . . . . . . . . . . . . 827
M. Srinivasan and
C. F. Edman and
H. Schulman Alternative splicing introduces a
nuclear localization signal that targets
multifunctional CaM kinase to the
nucleus . . . . . . . . . . . . . . . . 839
X. Shan and
Z. Xue and
T. Mél\`ese Yeast NPI46 encodes a novel prolyl
cis-trans isomerase that is located in
the nucleolus . . . . . . . . . . . . . 853
G. J. Bassell and
C. M. Powers and
K. L. Taneja and
R. H. Singer Single mRNAs visualized by
ultrastructural in situ hybridization
are principally localized at actin
filament intersections in fibroblasts 863
S. Huang and
T. J. Deerinck and
M. H. Ellisman and
D. L. Spector In vivo analysis of the stability and
transport of nuclear poly(A)+ RNA . . . 877
T. J. Deerinck and
M. E. Martone and
V. Lev-Ram and
D. P. Green and
R. Y. Tsien and
D. L. Spector and
S. Huang and
M. H. Ellisman Fluorescence photooxidation with eosin:
a method for high resolution
immunolocalization and in situ
hybridization detection for light and
electron microscopy . . . . . . . . . . 901
L. J. Kurihara and
C. T. Beh and
M. Latterich and
R. Schekman and
M. D. Rose Nuclear congression and membrane fusion:
two distinct events in the yeast
karyogamy pathway . . . . . . . . . . . 911
K. U. Kalies and
D. Görlich and
T. A. Rapoport Binding of ribosomes to the rough
endoplasmic reticulum mediated by the
Sec61p-complex . . . . . . . . . . . . . 925
D. Feldheim and
R. Schekman Sec72p contributes to the selective
recognition of signal peptides by the
secretory polypeptide translocation
complex . . . . . . . . . . . . . . . . 935
S. W. Whiteheart and
K. Rossnagel and
S. A. Buhrow and
M. Brunner and
R. Jaenicke and
J. E. Rothman N-ethylmaleimide-sensitive fusion
protein: a trimeric ATPase whose
hydrolysis of ATP is required for
membrane fusion . . . . . . . . . . . . 945
C. J. Cohen and
R. Bacon and
M. Clarke and
K. Joiner and
I. Mellman \bionameDictyostelium discoideum mutants
with conditional defects in phagocytosis 955
J. Calafat and
M. Nijenhuis and
H. Janssen and
A. Tulp and
S. Dusseljee and
R. Wubbolts and
J. Neefjes Major histocompatibility complex class
II molecules induce the formation of
endocytic MIIC-like structures . . . . . 967
S. Corvera and
A. Chawla and
R. Chakrabarti and
M. Joly and
J. Buxton and
M. P. Czech A double leucine within the GLUT4
glucose transporter COOH-terminal domain
functions as an endocytosis signal . . . 979
K. Matter and
E. M. Yamamoto and
I. Mellman Structural requirements and sequence
motifs for polarized sorting and
endocytosis of LDL and Fc receptors in
MDCK cells . . . . . . . . . . . . . . . 991
J. C. Norman and
L. S. Price and
A. J. Ridley and
A. Hall and
A. Koffer Actin filament organization in activated
mast cells is regulated by
heterotrimeric and small GTP-binding
proteins . . . . . . . . . . . . . . . . 1005
S. Barlow and
M. L. Gonzalez-Garay and
R. R. West and
J. B. Olmsted and
F. Cabral Stable expression of heterologous
microtubule-associated proteins (MAPs)
in Chinese hamster ovary cells: evidence
for differing roles of MAPs in
microtubule organization . . . . . . . . 1017
R. A. Nixon and
P. A. Paskevich and
R. K. Sihag and
C. Y. Thayer Phosphorylation on carboxyl terminus
domains of neurofilament proteins in
retinal ganglion cell neurons in vivo:
influences on regional neurofilament
accumulation, interneurofilament
spacing, and axon caliber . . . . . . . 1031
J. Kistler and
K. Goldie and
P. Donaldson and
A. Engel Reconstitution of native-type
noncrystalline lens fiber gap junctions
from isolated hemichannels . . . . . . . 1047
C. Borner and
I. Martinou and
C. Mattmann and
M. Irmler and
E. Schaerer and
J. C. Martinou and
J. Tschopp The protein bcl-2 alpha does not require
membrane attachment, but two conserved
domains to suppress apoptosis . . . . . 1059
Y. Ishizaki and
J. F. Burne and
M. C. Raff Autocrine signals enable chondrocytes to
survive in culture . . . . . . . . . . . 1069
M. Ohba and
M. Shibanuma and
T. Kuroki and
K. Nose Production of hydrogen peroxide by
transforming growth factor-beta 1 and
its involvement in induction of egr-1 in
mouse osteoblastic cells . . . . . . . . 1079
M. H. Wong and
M. T. Filbin The cytoplasmic domain of the myelin P0
protein influences the adhesive
interactions of its extracellular domain 1089
V. B. Lokeshwar and
N. Fregien and
L. Y. Bourguignon Ankyrin-binding domain of CD44(GP85) is
required for the expression of
hyaluronic acid-mediated adhesion
function . . . . . . . . . . . . . . . . 1099
G. Berton and
L. Fumagalli and
C. Laudanna and
C. Sorio Beta 2 integrin-dependent protein
tyrosine phosphorylation and activation
of the FGR protein tyrosine kinase in
human neutrophils . . . . . . . . . . . 1111
D. E. James and
R. C. Piper Insulin resistance, diabetes, and the
insulin-regulated trafficking of GLUT-4 1123
I. Nilsson and
P. Whitley and
G. von Heijne The COOH-terminal ends of internal
signal and signal-anchor sequences are
positioned differently in the ER
translocase . . . . . . . . . . . . . . 1127
M. F. Rexach and
M. Latterich and
R. W. Schekman Characteristics of endoplasmic
reticulum-derived transport vesicles . . 1133
L. Orci and
P. Halban and
A. Perrelet and
M. Amherdt and
M. Ravazzola and
R. G. Anderson pH-independent and -dependent cleavage
of proinsulin in the same secretory
vesicle . . . . . . . . . . . . . . . . 1149
H. Bosshart and
J. Humphrey and
E. Deignan and
J. Davidson and
J. Drazba and
L. Yuan and
V. Oorschot and
P. J. Peters and
J. S. Bonifacino The cytoplasmic domain mediates
localization of furin to the trans-Golgi
network en route to the
endosomal/lysosomal system . . . . . . . 1157
B. M. Mullock and
J. H. Perez and
T. Kuwana and
S. R. Gray and
J. P. Luzio Lysosomes can fuse with a late endosomal
compartment in a cell-free system from
rat liver . . . . . . . . . . . . . . . 1173
R. Rizzuto and
C. Bastianutto and
M. Brini and
M. Murgia and
T. Pozzan Mitochondrial Ca$^{2+}$ homeostasis in
intact cells . . . . . . . . . . . . . . 1183
A. Horowitz and
K. M. Trybus and
D. S. Bowman and
F. S. Fay Antibodies probe for folded monomeric
myosin in relaxed and contracted smooth
muscle . . . . . . . . . . . . . . . . . 1195
K. J. Eilertsen and
S. T. Kazmierski and
T. C. Keller Cellular titin localization in stress
fibers and interaction with myosin II
filaments in vitro . . . . . . . . . . . 1201
V. M. Latham and
E. H. Kislauskis and
R. H. Singer and
A. F. Ross Beta-actin mRNA localization is
regulated by signal transduction
mechanisms . . . . . . . . . . . . . . . 1211
M. A. Hill and
L. Schedlich and
P. Gunning Serum-induced signal transduction
determines the peripheral location of
beta-actin mRNA within the cell . . . . 1221
A. R. Menkel and
M. Kroemker and
P. Bubeck and
M. Ronsiek and
G. Nikolai and
B. M. Jockusch Characterization of an F-actin-binding
domain in the cytoskeletal protein
vinculin . . . . . . . . . . . . . . . . 1231
R. B. Nicklas and
S. C. Ward Elements of error correction in mitosis:
microtubule capture, release, and
tension . . . . . . . . . . . . . . . . 1241
S. J. King and
W. B. Inwood and
E. T. O'Toole and
J. Power and
S. K. Dutcher The bop2-1 mutation reveals radial
asymmetry in the inner dynein arm region
of \bionameChlamydomonas reinhardtii . . 1255
G. Müller and
E. A. Dearey and
A. Korndörfer and
W. Bandlow Stimulation of a
glycosyl-phosphatidylinositol-specific
phospholipase by insulin and the
sulfonylurea, glimepiride, in rat
adipocytes depends on increased glucose
transport . . . . . . . . . . . . . . . 1267
A. G. Arroyo and
M. R. Campanero and
P. Sánchez-Mateos and
J. M. Zapata and
M. A. Ursa and
M. A. del Pozo and
F. Sánchez-Madrid Induction of tyrosine phosphorylation
during ICAM-3 and LFA-1-mediated
intercellular adhesion, and its
regulation by the CD45 tyrosine
phosphatase . . . . . . . . . . . . . . 1277
S. E. LaFlamme and
L. A. Thomas and
S. S. Yamada and
K. M. Yamada Single subunit chimeric integrins as
mimics and inhibitors of endogenous
integrin functions in receptor
localization, cell spreading and
migration, and matrix assembly . . . . . 1287
M. W. Johansson and
E. Larsson and
B. Lüning and
E. B. Pasquale and
E. Ruoslahti Altered localization and cytoplasmic
domain-binding properties of
tyrosine-phosphorylated beta 1 integrin 1299
R. T. Ballock and
A. H. Reddi Thyroxine is the serum factor that
regulates morphogenesis of columnar
cartilage from isolated chondrocytes in
chemically defined medium . . . . . . . 1311
G. P. Kaushal and
P. D. Walker and
S. V. Shah An old enzyme with a new function:
purification and characterization of a
distinct matrix-degrading
metalloproteinase in rat kidney cortex
and its identification as meprin . . . . 1319
V. H. Meller and
M. McConnell and
P. A. Fisher An RNase-sensitive particle containing
\bionameDrosophila melanogaster DNA
topoisomerase II . . . . . . . . . . . . 1331
R. Ishida and
M. Sato and
T. Narita and
K. R. Utsumi and
T. Nishimoto and
T. Morita and
H. Nagata and
T. Andoh Inhibition of DNA topoisomerase II by
ICRF-193 induces polyploidization by
uncoupling chromosome dynamics from
other cell cycle events . . . . . . . . 1341
M. Somasundaran and
M. L. Zapp and
L. K. Beattie and
L. Pang and
K. S. Byron and
G. J. Bassell and
J. L. Sullivan and
R. H. Singer Localization of HIV RNA in mitochondria
of infected cells: potential role in
cytopathogenicity . . . . . . . . . . . 1353
L. F. Sogo and
M. P. Yaffe Regulation of mitochondrial morphology
and inheritance by Mdm10p, a protein of
the mitochondrial outer membrane . . . . 1361
S. M. Burgess and
M. Delannoy and
R. E. Jensen MMM1 encodes a mitochondrial outer
membrane protein essential for
establishing and maintaining the
structure of yeast mitochondria . . . . 1375
F. Peter and
C. Nuoffer and
S. N. Pind and
W. E. Balch Guanine nucleotide dissociation
inhibitor is essential for Rab1 function
in budding from the endoplasmic
reticulum and transport through the
Golgi stack . . . . . . . . . . . . . . 1393
R. Masaki and
A. Yamamoto and
Y. Tashiro Microsomal aldehyde dehydrogenase is
localized to the endoplasmic reticulum
via its carboxyl-terminal 35 amino acids 1407
A. L. Hitt and
T. H. Lu and
E. J. Luna Ponticulin is an atypical membrane
protein . . . . . . . . . . . . . . . . 1421
A. L. Hitt and
J. H. Hartwig and
E. J. Luna Ponticulin is the major high affinity
link between the plasma membrane and the
cortical actin network in
\bionameDictyostelium . . . . . . . . . 1433
O. Turunen and
T. Wahlström and
A. Vaheri Ezrin has a COOH-terminal actin-binding
site that is conserved in the ezrin
protein family . . . . . . . . . . . . . 1445
V. I. Rodionov and
S. S. Lim and
V. I. Gelfand and
G. G. Borisy Microtubule dynamics in fish
melanophores . . . . . . . . . . . . . . 1455
T. Horio and
B. R. Oakley Human gamma-tubulin functions in fission
yeast . . . . . . . . . . . . . . . . . 1465
M. Li and
M. McGrail and
M. Serr and
T. S. Hays Drosophila cytoplasmic dynein, a
microtubule motor that is asymmetrically
localized in the oocyte . . . . . . . . 1475
M. E. Porter and
J. A. Knott and
L. C. Gardner and
D. R. Mitchell and
S. K. Dutcher Mutations in the SUP--PF--1 locus of
\bionameChlamydomonas reinhardtii
identify a regulatory domain in the
beta-dynein heavy chain . . . . . . . . 1495
S. Reinsch and
E. Karsenti Orientation of spindle axis and
distribution of plasma membrane proteins
during cell division in polarized MDCKII
cells . . . . . . . . . . . . . . . . . 1509
C. Verderio and
S. Coco and
G. Fumagalli and
M. Matteoli Spatial changes in calcium signaling
during the establishment of neuronal
polarity and synaptogenesis . . . . . . 1527
R. Insall and
A. Kuspa and
P. J. Lilly and
G. Shaulsky and
L. R. Levin and
W. F. Loomis and
P. Devreotes CRAC, a cytosolic protein containing a
pleckstrin homology domain, is required
for receptor and G protein-mediated
activation of adenylyl cyclase in
\bionameDictyostelium . . . . . . . . . 1537
M. W. Crossman and
S. M. Hauft and
J. I. Gordon The mouse ileal lipid-binding protein
gene: a model for studying axial
patterning during gut morphogenesis . . 1547
J. Thorburn and
J. A. Frost and
A. Thorburn Mitogen-activated protein kinases
mediate changes in gene expression, but
not cytoskeletal organization associated
with cardiac muscle cell hypertrophy . . 1565
A. Youakim and
H. J. Hathaway and
D. J. Miller and
X. Gong and
B. D. Shur Overexpressing sperm surface beta
1,4-galactosyltransferase in transgenic
mice affects multiple aspects of
sperm-egg interactions . . . . . . . . . 1573
T. H. Lin and
A. Yurochko and
L. Kornberg and
J. Morris and
J. J. Walker and
S. Haskill and
R. L. Juliano The role of protein tyrosine
phosphorylation in integrin-mediated
gene induction in monocytes . . . . . . 1585
S. E. Gitelman and
M. S. Kobrin and
J. Q. Ye and
A. R. Lopez and
A. Lee and
R. Derynck Recombinant Vgr-1/BMP-$6$-expressing
tumors induce fibrosis and endochondral
bone formation in vivo . . . . . . . . . 1595
N. Amizuka and
H. Warshawsky and
J. E. Henderson and
D. Goltzman and
A. C. Karaplis Parathyroid hormone-related
peptide-depleted mice show abnormal
epiphyseal cartilage development and
altered endochondral bone formation . . 1611
S. Corvera and
A. Chawla and
R. Chakrabarti and
M. Joly and
J. Buxton and
M. P. Czech A double leucine within the GLUT4
glucose transporter COOH-terminal domain
functions as an endocytosis signal . . . 1625
T. A. Schroer New insights into the interaction of
cytoplasmic dynein with the
actin-related protein, Arp1 . . . . . . 1
G. H. Leno and
R. Munshi Initiation of DNA replication in nuclei
from quiescent cells requires
permeabilization of the nuclear membrane 5
K. Schulze-Osthoff and
H. Walczak and
W. Dröge and
P. H. Krammer Cell nucleus and DNA fragmentation are
not required for apoptosis . . . . . . . 15
F. M. Townsley and
G. Frigerio and
H. R. Pelham Retrieval of HDEL proteins is required
for growth of yeast cells . . . . . . . 21
M. S. Ladinsky and
J. R. Kremer and
P. S. Furcinitti and
J. R. McIntosh and
K. E. Howell HVEM tomography of the trans-Golgi
network: structural insights and
identification of a lace-like vesicle
coat . . . . . . . . . . . . . . . . . . 29
S. B. Sato and
S. Toyama Interference with the endosomal
acidification by a monoclonal antibody
directed toward the 116 (100)-kD subunit
of the vacuolar type proton pump . . . . 39
A. W. DeTomaso and
G. Blanco and
R. W. Mercer The alpha and beta subunits of the
Na,K--ATPase can assemble at the plasma
membrane into functional enzyme . . . . 55
S. Goetinck and
R. H. Waterston The \bionameCaenorhabditis elegans
UNC-87 protein is essential for
maintenance, but not assembly, of
bodywall muscle . . . . . . . . . . . . 71
S. Goetinck and
R. H. Waterston The \bionameCaenorhabditis elegans
muscle-affecting gene unc-87 encodes a
novel thin filament-associated protein 79
T. H. Smith and
A. M. Kachinsky and
J. B. Miller Somite subdomains, muscle cell origins,
and the four muscle regulatory factor
proteins . . . . . . . . . . . . . . . . 95
L. M. Machesky and
S. J. Atkinson and
C. Ampe and
J. Vandekerckhove and
T. D. Pollard Purification of a cortical complex
containing two unconventional actins
from \bionameAcanthamoeba by affinity
chromatography on profilin-agarose . . . 107
M. J. Brown and
L. M. Loew Electric field-directed fibroblast
locomotion involves cell surface
molecular reorganization and is calcium
independent . . . . . . . . . . . . . . 117
S. W. Clark and
D. I. Meyer ACT3: a putative centractin homologue in
S. cerevisiae is required for proper
orientation of the mitotic spindle . . . 129
M. Plamann and
P. F. Minke and
J. H. Tinsley and
K. S. Bruno Cytoplasmic dynein and actin-related
protein Arp1 are required for normal
nuclear distribution in filamentous
fungi . . . . . . . . . . . . . . . . . 139
S. M. Troyanovsky and
R. B. Troyanovsky and
L. G. Eshkind and
V. A. Krutovskikh and
R. E. Leube and
W. W. Franke Identification of the
plakoglobin-binding domain in desmoglein
and its role in plaque assembly and
intermediate filament anchorage . . . . 151
N. O. Ku and
M. B. Omary Identification of the major physiologic
phosphorylation site of human keratin
18: potential kinases and a role in
filament reorganization . . . . . . . . 161
S. Takeda and
S. Okabe and
T. Funakoshi and
N. Hirokawa Differential dynamics of
neurofilament--H protein and
neurofilament--L protein in neurons . . 173
Y. Sekine and
Y. Okada and
Y. Noda and
S. Kondo and
H. Aizawa and
R. Takemura and
N. Hirokawa A novel microtubule-based motor protein
(KIF4) for organelle transports, whose
expression is regulated developmentally 187
M. K. Stachowiak and
J. Moffett and
A. Joy and
E. Puchacz and
R. Florkiewicz and
E. K. Stachowiak Regulation of bFGF gene expression and
subcellular distribution of bFGF protein
in adrenal medullary cells . . . . . . . 203
E. M. Rosen and
A. Joseph and
L. Jin and
S. Rockwell and
J. A. Elias and
J. Knesel and
J. Wines and
J. McClellan and
M. J. Kluger and
I. D. Goldberg Regulation of scatter factor production
via a soluble inducing factor . . . . . 225
A. Nagafuchi and
S. Ishihara and
S. Tsukita The roles of catenins in the
cadherin-mediated cell adhesion:
functional analysis of E-cadherin-alpha
catenin fusion molecules . . . . . . . . 235
M. Watabe and
A. Nagafuchi and
S. Tsukita and
M. Takeichi Induction of polarized cell--cell
association and retardation of growth by
activation of the E-cadherin-catenin
adhesion system in a dispersed carcinoma
line . . . . . . . . . . . . . . . . . . 247
T. J. Wickham and
E. J. Filardo and
D. A. Cheresh and
G. R. Nemerow Integrin alpha v beta 5 selectively
promotes adenovirus mediated cell
membrane permeabilization . . . . . . . 257
H. Scherthan and
J. Bähler and
J. Kohli Dynamics of chromosome organization and
pairing during meiotic prophase in
fission yeast . . . . . . . . . . . . . 273
A. S. Belmont and
K. Bruce Visualization of G1 chromosomes: a
folded, twisted, supercoiled chromonema
model of interphase chromatid structure 287
N. Saitoh and
I. G. Goldberg and
E. R. Wood and
W. C. Earnshaw ScII: an abundant chromosome scaffold
protein is a member of a family of
putative ATPases with an unusual
predicted tertiary structure . . . . . . 303
A. M. Bogerd and
J. A. Hoffman and
D. C. Amberg and
G. R. Fink and
L. I. Davis nup1 mutants exhibit pleiotropic defects
in nuclear pore complex function . . . . 319
J. Vidugiriene and
A. K. Menon The GPI anchor of cell-surface proteins
is synthesized on the cytoplasmic face
of the endoplasmic reticulum . . . . . . 333
M. M. Falk and
N. M. Kumar and
N. B. Gilula Membrane insertion of gap junction
connexins: polytopic channel forming
membrane proteins . . . . . . . . . . . 343
D. K. Banfield and
M. J. Lewis and
C. Rabouille and
G. Warren and
H. R. Pelham Localization of Sed5, a putative vesicle
targeting molecule, to the cis-Golgi
network involves both its transmembrane
and cytoplasmic domains . . . . . . . . 357
A. L. Munn and
H. Riezman Endocytosis is required for the growth
of vacuolar H(+)-ATPase-defective yeast:
identification of six new END genes . . 373
R. A. Bacon and
C. J. Cohen and
D. A. Lewin and
I. Mellman \bionameDictyostelium discoideum mutants
with temperature-sensitive defects in
endocytosis . . . . . . . . . . . . . . 387
J. C. Wilton and
G. M. Matthews and
R. D. Burgoyne and
C. O. Mills and
J. K. Chipman and
R. Coleman Fluorescent choleretic and cholestatic
bile salts take different paths across
the hepatocyte: transcytosis of
glycolithocholate leads to an extensive
redistribution of annexin II . . . . . . 401
M. Radermacher and
V. Rao and
R. Grassucci and
J. Frank and
A. P. Timerman and
S. Fleischer and
T. Wagenknecht Cryo-electron microscopy and
three-dimensional reconstruction of the
calcium release channel/ryanodine
receptor from skeletal muscle . . . . . 411
T. Hasson and
M. S. Mooseker Porcine myosin-VI: characterization of a
new mammalian unconventional myosin . . 425
E. H. Kislauskis and
X. Zhu and
R. H. Singer Sequences responsible for intracellular
localization of beta-actin messenger RNA
also affect cell phenotype . . . . . . . 441
D. A. Schafer and
Y. O. Korshunova and
T. A. Schroer and
J. A. Cooper Differential localization and sequence
analysis of capping protein beta-subunit
isoforms of vertebrates . . . . . . . . 453
J. P. Tassan and
S. J. Schultz and
J. Bartek and
E. A. Nigg Cell cycle analysis of the activity,
subcellular localization, and subunit
composition of human CAK (CDK-activating
kinase) . . . . . . . . . . . . . . . . 467
J. C. Yu and
J. S. Gutkind and
D. Mahadevan and
W. Li and
K. A. Meyers and
J. H. Pierce and
M. A. Heidaran Biological function of PDGF-induced PI-3
kinase activity: its role in alpha PDGF
receptor-mediated mitogenic signaling 479
S. H. Gilbert and
K. Perry and
F. S. Fay Mediation of chemoattractant-induced
changes in [Ca$^{2+}$]i and cell shape,
polarity, and locomotion by InsP3, DAG,
and protein kinase C in newt eosinophils 489
K. Takahashi and
J. Folmer and
P. A. Coulombe Increased expression of keratin 16
causes anomalies in cytoarchitecture and
keratinization in transgenic mouse skin 505
S. Dufour and
J. P. Saint-Jeannet and
F. Broders and
D. Wedlich and
J. P. Thiery Differential perturbations in the
morphogenesis of anterior structures
induced by overexpression of truncated
XB- and N-cadherins in \bionameXenopus
embryos . . . . . . . . . . . . . . . . 521
F. Re and
A. Zanetti and
M. Sironi and
N. Polentarutti and
L. Lanfrancone and
E. Dejana and
F. Colotta Inhibition of anchorage-dependent cell
spreading triggers apoptosis in cultured
human endothelial cells . . . . . . . . 537
M. Agrez and
A. Chen and
R. I. Cone and
R. Pytela and
D. Sheppard The alpha v beta 6 integrin promotes
proliferation of colon carcinoma cells
through a unique region of the beta 6
cytoplasmic domain . . . . . . . . . . . 547
F. Balzac and
S. F. Retta and
A. Albini and
A. Melchiorri and
V. E. Koteliansky and
M. Geuna and
L. Silengo and
G. Tarone Expression of beta 1B integrin isoform
in CHO cells results in a dominant
negative effect on cell adhesion and
motility . . . . . . . . . . . . . . . . 557
T. Roemer and
G. Paravicini and
M. A. Payton and
H. Bussey Characterization of the yeast (1 $\to$
6)-beta-glucan biosynthetic components,
Kre6p and Skn1p, and genetic
interactions between the PKC1 pathway
and extracellular matrix assembly . . . 567
K. F. Sullivan and
M. Hechenberger and
K. Masri Human CENP--A contains a histone H3
related histone fold domain that is
required for targeting to the centromere 581
B. J. Blencowe and
J. A. Nickerson and
R. Issner and
S. Penman and
P. A. Sharp Association of nuclear matrix antigens
with exon-containing splicing complexes 593
T. Durfee and
M. A. Mancini and
D. Jones and
S. J. Elledge and
W. H. Lee The amino-terminal region of the
retinoblastoma gene product binds a
novel nuclear matrix protein that
co-localizes to centers for RNA
processing . . . . . . . . . . . . . . . 609
B. M. Benton and
J. H. Zang and
J. Thorner A novel FK506- and rapamycin-binding
protein (FPR3 gene product) in the yeast
\bionameSaccharomyces cerevisiae is a
proline rotamase localized to the
nucleolus . . . . . . . . . . . . . . . 623
C. N. Connolly and
C. E. Futter and
A. Gibson and
C. R. Hopkins and
D. F. Cutler Transport into and out of the Golgi
complex studied by transfecting cells
with cDNAs encoding horseradish
peroxidase . . . . . . . . . . . . . . . 641
E. C. Gaynor and
S. te Heesen and
T. R. Graham and
M. Aebi and
S. D. Emr Signal-mediated retrieval of a membrane
protein from the Golgi to the ER in
yeast . . . . . . . . . . . . . . . . . 653
T. R. Graham and
M. Seeger and
G. S. Payne and
V. L. MacKay and
S. D. Emr Clathrin-dependent localization of alpha
1,3 mannosyltransferase to the Golgi
complex of \bionameSaccharomyces
cerevisiae . . . . . . . . . . . . . . . 667
S. D. Podos and
P. Reddy and
J. Ashkenas and
M. Krieger LDLC encodes a brefeldin A-sensitive,
peripheral Golgi protein required for
normal Golgi function . . . . . . . . . 679
L. Carnell and
H. P. Moore Transport via the regulated secretory
pathway in semi-intact PC12 cells: role
of intra-cisternal calcium and pH in the
transport and sorting of secretogranin
II . . . . . . . . . . . . . . . . . . . 693
K. A. Beck and
J. A. Buchanan and
V. Malhotra and
W. J. Nelson Golgi spectrin: identification of an
erythroid beta-spectrin homolog
associated with the Golgi complex . . . 707
P. Cupers and
A. Veithen and
A. Kiss and
P. Baudhuin and
P. J. Courtoy Clathrin polymerization is not required
for bulk-phase endocytosis in rat fetal
fibroblasts . . . . . . . . . . . . . . 725
H. R. Waterham and
V. I. Titorenko and
P. Haima and
J. M. Cregg and
W. Harder and
M. Veenhuis The Hansenula polymorpha PER1 gene is
essential for peroxisome biogenesis and
encodes a peroxisomal matrix protein
with both carboxy- and amino-terminal
targeting signals . . . . . . . . . . . 737
D. R. Johnson and
L. J. Knoll and
D. E. Levin and
J. I. Gordon Saccharomyces cerevisiae contains four
fatty acid activation (FAA) genes: an
assessment of their role in regulating
protein N-myristoylation and cellular
lipid metabolism . . . . . . . . . . . . 751
K. Hirose and
C. Franzini-Armstrong and
Y. E. Goldman and
J. M. Murray Structural changes in muscle
crossbridges accompanying force
generation . . . . . . . . . . . . . . . 763
M. Caplow and
R. L. Ruhlen and
J. Shanks The free energy for hydrolysis of a
microtubule-bound nucleotide
triphosphate is near zero: all of the
free energy for hydrolysis is stored in
the microtubule lattice . . . . . . . . 779
P. R. Andreassen and
R. L. Margolis Microtubule dependency of p34cdc2
inactivation and mitotic exit in
mammalian cells . . . . . . . . . . . . 789
R. A. Bloodgood and
N. L. Salomonsky The transmembrane signaling pathway
involved in directed movements of
\bionameChlamydomonas flagellar membrane
glycoproteins involves the
dephosphorylation of a 60-kD
phosphoprotein that binds to the major
flagellar membrane glycoprotein . . . . 803
W. J. Chen and
R. K. Liem Reexpression of glial fibrillary acidic
protein rescues the ability of
astrocytoma cells to form processes in
response to neurons . . . . . . . . . . 813
H. E. Beggs and
P. Soriano and
P. F. Maness NCAM-dependent neurite outgrowth is
inhibited in neurons from Fyn-minus mice 825
J. P. Magyar and
U. Bartsch and
Z. Q. Wang and
N. Howells and
A. Aguzzi and
E. F. Wagner and
M. Schachner Degeneration of neural cells in the
central nervous system of mice deficient
in the gene for the adhesion molecule on
Glia, the beta 2 subunit of murine
Na,K--ATPase . . . . . . . . . . . . . . 835
P. Chen and
H. Xie and
M. C. Sekar and
K. Gupta and
A. Wells Epidermal growth factor
receptor-mediated cell motility:
phospholipase C activity is required,
but mitogen-activated protein kinase
activity is not sufficient for induced
cell movement . . . . . . . . . . . . . 847
R. L. Klemke and
M. Yebra and
E. M. Bayna and
D. A. Cheresh Receptor tyrosine kinase signaling
required for integrin alpha v beta
$5$-directed cell motility but not
adhesion on vitronectin . . . . . . . . 859
M. R. Campanero and
P. Sánchez-Mateos and
M. A. del Pozo and
F. Sánchez-Madrid ICAM-3 regulates lymphocyte morphology
and integrin-mediated T cell interaction
with endothelial cell and extracellular
matrix ligands . . . . . . . . . . . . . 867
J. H. Miner and
J. R. Sanes Collagen IV alpha 3, alpha 4, and alpha
5 chains in rodent basal laminae:
sequence, distribution, association with
laminins, and developmental switches . . 879
J. M. Herrmann and
R. A. Stuart and
E. A. Craig and
W. Neupert Mitochondrial heat shock protein 70, a
molecular chaperone for proteins encoded
by mitochondrial DNA . . . . . . . . . . 893
B. Baccetti and
A. Benedetto and
A. G. Burrini and
G. Collodel and
E. C. Ceccarini and
N. Crisa and
A. Di Caro and
M. Estenoz and
A. R. Garbuglia and
A. Massacesi and
P. Piomboni and
T. Renieri and
D. Solazzo HIV-particles in spermatozoa of patients
with AIDS and their transfer into the
oocyte . . . . . . . . . . . . . . . . . 903
H. Damke and
T. Baba and
D. E. Warnock and
S. L. Schmid Induction of mutant dynamin specifically
blocks endocytic coated vesicle
formation . . . . . . . . . . . . . . . 915
C. Erxleben and
H. Plattner Ca$^{2+}$ release from subplasmalemmal
stores as a primary event during
exocytosis in Paramecium cells . . . . . 935
C. J. Beckers and
J. F. Dubremetz and
O. Mercereau-Puijalon and
K. A. Joiner The Toxoplasma gondii rhoptry protein
ROP 2 is inserted into the
parasitophorous vacuole membrane,
surrounding the intracellular parasite,
and is exposed to the host cell
cytoplasm . . . . . . . . . . . . . . . 947
Y. L. Wang and
J. D. Silverman and
L. G. Cao Single particle tracking of surface
receptor movement during cell division 963
D. Hamill and
J. Davis and
J. Drawbridge and
K. A. Suprenant Polyribosome targeting to microtubules:
enrichment of specific mRNAs in a
reconstituted microtubule preparation
from sea urchin embryos . . . . . . . . 973
R. J. Vasquez and
D. L. Gard and
L. Cassimeris XMAP from \bionameXenopus eggs promotes
rapid plus end assembly of microtubules
and rapid microtubule polymer turnover 985
P. K. Sorger and
F. F. Severin and
A. A. Hyman Factors required for the binding of
reassembled yeast kinetochores to
microtubules in vitro . . . . . . . . . 995
S. X. Lin and
K. L. Ferro and
C. A. Collins Cytoplasmic dynein undergoes
intracellular redistribution concomitant
with phosphorylation of the heavy chain
in response to serum starvation and
okadaic acid . . . . . . . . . . . . . . 1009
F. Feiguin and
A. Ferreira and
K. S. Kosik and
A. Caceres Kinesin-mediated organelle translocation
revealed by specific cellular
manipulations . . . . . . . . . . . . . 1021
P. A. Pesavento and
R. J. Stewart and
L. S. Goldstein Characterization of the KLP68D
kinesin-like protein in
\bionameDrosophila: possible roles in
axonal transport . . . . . . . . . . . . 1041
P. D. Kouklis and
E. Hutton and
E. Fuchs Making a connection: direct binding
between keratin intermediate filaments
and desmosomal proteins . . . . . . . . 1049
R. N. Michel and
C. Q. Vu and
W. Tetzlaff and
B. J. Jasmin Neural regulation of
acetylcholinesterase mRNAs at mammalian
neuromuscular synapses . . . . . . . . . 1061
B. Varnum-Finney and
L. F. Reichardt Vinculin-deficient PC12 cell lines
extend unstable lamellipodia and
filopodia and have a reduced rate of
neurite outgrowth . . . . . . . . . . . 1071
S. M. Frisch E1a induces the expression of epithelial
characteristics . . . . . . . . . . . . 1085
Y. Yang and
E. Spitzer and
N. Kenney and
W. Zschiesche and
M. Li and
A. Kromminga and
T. Müller and
F. Spener and
A. Lezius and
J. H. Veerkamp Members of the fatty acid binding
protein family are differentiation
factors for the mammary gland . . . . . 1097
A. Zimmer and
A. M. Zimmer and
K. Reynolds Tissue specific expression of the
retinoic acid receptor-beta 2:
regulation by short open reading frames
in the 5'-noncoding region . . . . . . . 1111
S. K. Gupta and
J. P. Singh Inhibition of endothelial cell
proliferation by platelet factor-4
involves a unique action on S phase
progression . . . . . . . . . . . . . . 1121
S. D. Blystone and
I. L. Graham and
F. P. Lindberg and
E. J. Brown Integrin alpha v beta 3 differentially
regulates adhesive and phagocytic
functions of the fibronectin receptor
alpha 5 beta 1 . . . . . . . . . . . . . 1129
I. L. Graham and
D. C. Anderson and
V. M. Holers and
E. J. Brown Complement receptor 3 (CR3, Mac-1,
integrin alpha M beta 2, CD11b/CD18) is
required for tyrosine phosphorylation of
paxillin in adherent and nonadherent
neutrophils . . . . . . . . . . . . . . 1139
C. Chenu and
S. Colucci and
M. Grano and
P. Zigrino and
R. Barattolo and
G. Zambonin and
N. Baldini and
P. Vergnaud and
P. D. Delmas and
A. Z. Zallone Osteocalcin induces chemotaxis,
secretion of matrix proteins, and
calcium-mediated intracellular signaling
in human osteoclast-like cells . . . . . 1149
M. C. Avides and
C. E. Sunkel Isolation of chromosome-associated
proteins from \bionameDrosophila
melanogaster that bind a human
centromeric DNA sequence . . . . . . . . 1159
S. M. Wilson and
K. V. Datar and
M. R. Paddy and
J. R. Swedlow and
M. S. Swanson Characterization of nuclear
polyadenylated RNA-binding proteins in
\bionameSaccharomyces cerevisiae . . . . 1173
E. J. Smart and
Y. S. Ying and
P. A. Conrad and
R. G. Anderson Caveolin moves from caveolae to the
Golgi apparatus in response to
cholesterol oxidation . . . . . . . . . 1185
R. G. Parton and
B. Joggerst and
K. Simons Regulated internalization of caveolae 1199
J. E. Schnitzer and
P. Oh and
E. Pinney and
J. Allard Filipin-sensitive caveolae-mediated
transport in endothelium: reduced
transcytosis, scavenger endocytosis, and
capillary permeability of select
macromolecules . . . . . . . . . . . . . 1217
P. E. Scherer and
M. P. Lisanti and
G. Baldini and
M. Sargiacomo and
C. C. Mastick and
H. F. Lodish Induction of caveolin during
adipogenesis and association of GLUT4
with caveolin-rich vesicles . . . . . . 1233
J. A. McNew and
J. M. Goodman An oligomeric protein is imported into
peroxisomes in vivo . . . . . . . . . . 1245
J. A. Heyman and
E. Monosov and
S. Subramani Role of the PAS1 gene of Pichia pastoris
in peroxisome biogenesis . . . . . . . . 1259
B. A. Block and
J. O'Brien and
G. Meissner Characterization of the sarcoplasmic
reticulum proteins in the thermogenic
muscles of fish . . . . . . . . . . . . 1275
S. S. Andersen and
B. Buendia and
J. E. Domínguez and
A. Sawyer and
E. Karsenti Effect on microtubule dynamics of
XMAP230, a microtubule-associated
protein present in \bionameXenopus
laevis eggs and dividing cells . . . . . 1289
C. L. Rieder and
A. Schultz and
R. Cole and
G. Sluder Anaphase onset in vertebrate somatic
cells is controlled by a checkpoint that
monitors sister kinetochore attachment
to the spindle . . . . . . . . . . . . . 1301
L. C. Gardner and
E. O'Toole and
C. A. Perrone and
T. Giddings and
M. E. Porter Components of a ``dynein regulatory
complex'' are located at the junction
between the radial spokes and the dynein
arms in \bionameChlamydomonas flagella 1311
M. J. Monteiro and
C. Hicks and
L. Gu and
S. Janicki Determinants for intracellular sorting
of cytoplasmic and nuclear intermediate
filaments . . . . . . . . . . . . . . . 1327
D. Strand and
I. Raska and
B. M. Mechler The \bionameDrosophila lethal(2)giant
larvae tumor suppressor protein is a
component of the cytoskeleton . . . . . 1345
D. Strand and
R. Jakobs and
G. Merdes and
B. Neumann and
A. Kalmes and
H. W. Heid and
I. Husmann and
B. M. Mechler The \bionameDrosophila lethal(2)giant
larvae tumor suppressor protein forms
homo-oligomers and is associated with
nonmuscle myosin II heavy chain . . . . 1361
H. Hoschuetzky and
H. Aberle and
R. Kemler Beta-catenin mediates the interaction of
the cadherin-catenin complex with
epidermal growth factor receptor . . . . 1375
Y. J. Kim and
L. Francisco and
G. C. Chen and
E. Marcotte and
C. S. Chan Control of cellular morphogenesis by the
Ip12/Bem2 GTPase-activating protein:
possible role of protein phosphorylation 1381
J. Peterson and
Y. Zheng and
L. Bender and
A. Myers and
R. Cerione and
A. Bender Interactions between the bud emergence
proteins Bem1p and Bem2p and Rho-type
GTPases in yeast . . . . . . . . . . . . 1395
C. L. Smith The initiation of neurite outgrowth by
sympathetic neurons grown in vitro does
not depend on assembly of microtubules 1407
Y. Liu and
E. S. Schweitzer and
M. J. Nirenberg and
V. M. Pickel and
C. J. Evans and
R. H. Edwards Preferential localization of a vesicular
monoamine transporter to dense core
vesicles in PC12 cells . . . . . . . . . 1419
E. A. Connor and
K. Qin and
H. Yankelev and
D. DeStefano Synaptic activity and connective tissue
remodeling in denervated frog muscle . . 1435
Q. Zhang and
W. J. Checovich and
D. M. Peters and
R. M. Albrecht and
D. F. Mosher Modulation of cell surface fibronectin
assembly sites by lysophosphatidic acid 1447
J. L. Bixby and
G. B. Grunwald and
R. J. Bookman Ca$^{2+}$ influx and neurite growth in
response to purified N-cadherin and
laminin . . . . . . . . . . . . . . . . 1461
M. Fuortes and
W. W. Jin and
C. Nathan Beta 2 integrin-dependent tyrosine
phosphorylation of paxillin in human
neutrophils treated with tumor necrosis
factor . . . . . . . . . . . . . . . . . 1477
R. Alon and
H. Rossiter and
X. Wang and
T. A. Springer and
T. S. Kupper Distinct cell surface ligands mediate T
lymphocyte attachment and rolling on P
and E selectin under physiological flow 1485
L. M. Coluccio An end in sight: tropomodulin . . . . . 1497
K. S. Kosik The Alzheimer's disease sphinx: a riddle
with plaques and tangles . . . . . . . . 1501
J. A. Hammer Regulation of \bionameDictyostelium
myosin II by phosphorylation: what is
essential and what is important? . . . . 1779
E. M. Rosen and
S. K. Nigam and
I. D. Goldberg Scatter factor and the c-met receptor: a
paradigm for mesenchymal/epithelial
interaction . . . . . . . . . . . . . . 1783
U. T. Meier and
G. Blobel NAP57, a mammalian nucleolar protein
with a putative homolog in yeast and
bacteria . . . . . . . . . . . . . . . . 1505
D. A. Byrd and
D. J. Sweet and
N. Panté and
K. N. Konstantinov and
T. Guan and
A. C. Saphire and
P. J. Mitchell and
C. S. Cooper and
U. Aebi and
L. Gerace Tpr, a large coiled coil protein whose
amino terminus is involved in activation
of oncogenic kinases, is localized to
the cytoplasmic surface of the nuclear
pore complex . . . . . . . . . . . . . . 1515
M. Pruschy and
Y. Ju and
L. Spitz and
E. Carafoli and
D. S. Goldfarb Facilitated nuclear transport of
calmodulin in tissue culture cells . . . 1527
S. P. Mayfield and
A. Cohen and
A. Danon and
C. B. Yohn Translation of the psbA mRNA of
\bionameChlamydomonas reinhardtii
requires a structured RNA element
contained within the 5' untranslated
region . . . . . . . . . . . . . . . . . 1537
J. Rassow and
A. C. Maarse and
E. Krainer and
M. Kübrich and
H. Müller and
M. Meijer and
E. A. Craig and
N. Pfanner Mitochondrial protein import:
biochemical and genetic evidence for
interaction of matrix hsp70 and the
inner membrane protein MIM44 . . . . . . 1547
G. Griffiths and
M. Ericsson and
J. Krijnse-Locker and
T. Nilsson and
B. Goud and
H. D. Söling and
B. L. Tang and
S. H. Wong and
W. Hong Localization of the Lys, Asp, Glu, Leu
tetrapeptide receptor to the Golgi
complex and the intermediate compartment
in mammalian cells . . . . . . . . . . . 1557
O. Martinez and
A. Schmidt and
J. Salaméro and
B. Hoflack and
M. Roa and
B. Goud The small GTP-binding protein rab6
functions in intra-Golgi transport . . . 1575
R. E. Leube and
U. Leimer and
C. Grund and
W. W. Franke and
N. Harth and
B. Wiedenmann Sorting of synaptophysin into special
vesicles in nonneuroendocrine epithelial
cells . . . . . . . . . . . . . . . . . 1589
F. Bonzelius and
G. A. Herman and
M. H. Cardone and
K. E. Mostov and
R. B. Kelly The polymeric immunoglobulin receptor
accumulates in specialized endosomes but
not synaptic vesicles within the
neurites of transfected neuroendocrine
PC12 cells . . . . . . . . . . . . . . . 1603
M. Furuse and
M. Itoh and
T. Hirase and
A. Nagafuchi and
S. Yonemura and
S. Tsukita and
S. Tsukita Direct association of occludin with ZO-1
and its possible involvement in the
localization of occludin at tight
junctions . . . . . . . . . . . . . . . 1617
A. Weber and
C. R. Pennise and
G. G. Babcock and
V. M. Fowler Tropomodulin caps the pointed ends of
actin filaments . . . . . . . . . . . . 1627
G. von Dassow and
G. Schubiger How an actin network might cause
fountain streaming and nuclear migration
in the syncytial \bionameDrosophila
embryo . . . . . . . . . . . . . . . . . 1637
I. Samejima and
M. Yanagida Bypassing anaphase by fission yeast cut9
mutation: requirement of cut9+ to
initiate anaphase . . . . . . . . . . . 1655
J. F. Dillman and
K. K. Pfister Differential phosphorylation in vivo of
cytoplasmic dynein associated with
anterogradely moving organelles . . . . 1671
D. R. Howard and
G. Habermacher and
D. B. Glass and
E. F. Smith and
W. S. Sale Regulation of \bionameChlamydomonas
flagellar dynein by an axonemal protein
kinase . . . . . . . . . . . . . . . . . 1683
J. Q. Zheng and
Z. Zheng and
M. Poo Long-range signaling in growing neurons
after local elevation of cyclic
AMP-dependent activity . . . . . . . . . 1693
P. Milev and
D. R. Friedlander and
T. Sakurai and
L. Karthikeyan and
M. Flad and
R. K. Margolis and
M. Grumet and
R. U. Margolis Interactions of the chondroitin sulfate
proteoglycan phosphacan, the
extracellular domain of a receptor-type
protein tyrosine phosphatase, with
neurons, glia, and neural cell adhesion
molecules . . . . . . . . . . . . . . . 1703
S. Estus and
W. J. Zaks and
R. S. Freeman and
M. Gruda and
R. Bravo and
E. M. Johnson Altered gene expression in neurons
during programmed cell death:
identification of c-jun as necessary for
neuronal apoptosis . . . . . . . . . . . 1717
F. A. Flomerfelt and
R. L. Miesfeld Recessive mutations in a common pathway
block thymocyte apoptosis induced by
multiple signals . . . . . . . . . . . . 1729
F. Galimi and
G. P. Bagnara and
L. Bonsi and
E. Cottone and
A. Follenzi and
A. Simeone and
P. M. Comoglio Hepatocyte growth factor induces
proliferation and differentiation of
multipotent and erythroid hemopoietic
progenitors . . . . . . . . . . . . . . 1743
T. Katagiri and
A. Yamaguchi and
M. Komaki and
E. Abe and
N. Takahashi and
T. Ikeda and
V. Rosen and
J. M. Wozney and
A. Fujisawa-Sehara and
T. Suda Bone morphogenetic protein-2 converts
the differentiation pathway of C2C12
myoblasts into the osteoblast lineage 1755
U. M. Wewer and
K. Ibaraki and
P. Schjòrring and
M. E. Durkin and
M. F. Young and
R. Albrechtsen A potential role for tetranectin in
mineralization during osteogenesis . . . 1767
T. A. Schroer and
E. Fyrberg and
J. A. Cooper and
R. H. Waterston and
D. Helfman and
T. D. Pollard and
D. I. Meyer Actin-related protein nomenclature and
classification . . . . . . . . . . . . . 1777
E. Schulze and
S. Nagel and
K. Gavenis and
U. Grossbach Structurally divergent histone H1
variants in chromosomes containing
highly condensed interphase chromatin 1789
E. de Beus and
J. S. Brockenbrough and
B. Hong and
J. P. Aris Yeast NOP2 encodes an essential
nucleolar protein with homology to a
human proliferation marker . . . . . . . 1799
P. J. Weidman and
W. M. Winter The G protein-activating peptide,
mastoparan, and the synthetic
NH2-terminal ARF peptide, ARFp13,
inhibit in vitro Golgi transport by
irreversibly damaging membranes . . . . 1815
M. Vey and
W. Schäfer and
S. Berghöfer and
H. D. Klenk and
W. Garten Maturation of the trans-Golgi network
protease furin: compartmentalization of
propeptide removal, substrate cleavage,
and COOH-terminal truncation . . . . . . 1829
K. C. Hart and
Y. F. Xu and
A. N. Meyer and
B. A. Lee and
D. J. Donoghue The v-sis oncoprotein loses transforming
activity when targeted to the early
Golgi complex . . . . . . . . . . . . . 1843
S. Dahan and
J. P. Ahluwalia and
L. Wong and
B. I. Posner and
J. J. Bergeron Concentration of intracellular hepatic
apolipoprotein E in Golgi apparatus
saccular distensions and endosomes . . . 1859
L. Zhang and
C. L. Ashendel and
G. W. Becker and
D. J. Morré Isolation and characterization of the
principal ATPase associated with
transitional endoplasmic reticulum of
rat liver . . . . . . . . . . . . . . . 1871
J. Zimmerberg and
R. Blumenthal and
D. P. Sarkar and
M. Curran and
S. J. Morris Restricted movement of lipid and aqueous
dyes through pores formed by influenza
hemagglutinin during cell fusion . . . . 1885
P. D. Lampe Analyzing phorbol ester effects on gap
junctional communication: a dramatic
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