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Volume 7, Number 1, February, 1960Daniel Mazia and Patricia J. Harris and Thomas Bibring The Multiplicity of the Mitotic Centers and the Time--Course of Their Duplication and Separation . . . . . . . 1 R. E. Kane The Effect of Partial Protein Extraction on the Structure of the Eggs of the Sea Urchin, Arbacia punctulata . . . . . . . 21 Henry Finck Epoxy Resins in Electron Microscopy . . 27 A. J. de Lorenzo The Fine Structure of Synapses in the Ciliary Ganglion of the Chick . . . . . 31 David S. Jackson and John P. Bentley On the Significance of the Extractable Collagens . . . . . . . . . . . . . . . 37 Fred Rapp and Irving Gordon and Richard F. Baker Observations of Measles Virus Infection of Cultured Human Cells . . . . . . . . 43 Joseph C. Arcos and George W. Griffith and Richard W. Cunningham Fine Structural Alterations in Cell Particles During Chemical Carcinogenesis 49 David A. Karnofsky and Ross S. Basch Effects of 5-Fluorodeoxyuridine and Related Halogenated Pyrimidines on the Sand--Dollar Embryo . . . . . . . . . . 61 G. Yasuzumi Spermatogenesis in Animals as Revealed by Electron Microscopy . . . . . . . . . 73 J. R. K. Savage and G. J. Neary and H. J. Evans The Rejoining Time of Chromatid Breaks Induced by Gamma Radiation in \bionameVicia faba Root Tips at 3$^\circ $C . . . . . . . . . . . . . . . . . . . 79 M. F. Moody and J. D. Robertson The Fine Structure of Some Retinal Photoreceptors . . . . . . . . . . . . . 87 Clay G. Huff and Alan C. Pipkin and A. B. Weathersby and Dinniemaud V. Jensen The Morphology and Behavior of Living Exoerythrocytic Stages of Plasmodium gallinaceum and P. fallax and Their Host Cells . . . . . . . . . . . . . . . . . 93 J. B. Longley and W. G. Banfield and D. C. Brindley Structure of the Rete Mirabile in the Kidney of the Rat as Seen with the Electron Microscope . . . . . . . . . . 103 Humberto R. Maturana The Fine Anatomy of the Optic Nerve of \bionameAnurans --- an Electron Microscope Study . . . . . . . . . . . . 107 A. Peters The Structure of Myelin Sheaths in the Central Nervous System of \bionameXenopus laevis (Daudin) . . . . 121 Benigna Blondel and Gilbert Turian Relation Between Basophilia and Fine Structure of Cytoplasm in the Fungus Allomyces macrogynus Em . . . . . . . . 127 Paul R. Gross and Delbert E. Philpott and Sylvan Nass Electron Microscopy of the Centrifuged Sea Urchin Egg, with a Note on the Structure of the Ground Cytoplasm . . . 135 Lawrence Herman An Electron Microscope Study of the Salamander Thyroid during Hormonal Stimulation . . . . . . . . . . . . . . 143 R. W. Merriam and William E. Koch The Relative Concentration of Solids in the Nucleolus, Nucleus, and Cytoplasm of the Developing Nerve Cell of the Chick 151 A. M. Lawn Observations on the Fine Structure of the Gastric Parietal Cell of the Rat . . 161 Keith R. Porter and Raul D. Machado Studies on the Endoplasmic Reticulum . . 167 H. E. Karrer Cell Interconnections in Normal Human Cervical Epithelium . . . . . . . . . . 181 O. Trujillo-Cenóz The Fine Structure of a Special Type of Nerve Fiber Found in the Ganglia of \bionameArmadillidium vulgare (Crustacea--Isopoda) . . . . . . . . . . 185 Kiyoteru Tokuyasu and Eichi Yamada The Fine Structure of the Retina. V. Abnormal Retinal Rods and their Morphogenesis . . . . . . . . . . . . . 187 William Bloom Preparation of a Selected Cell for Electron Microscopy . . . . . . . . . . 191 Tadayo Hashimoto and Philipp Gerhardt Monochromatic Ultraviolet Microscopy of Microorganisms: Preliminary Observations on Bacterial Spores . . . . . . . . . . 195 A. M. Lawn The Use of Potassium Permanganate as an Electron--Dense Stain for Sections of Tissue Embedded in Epoxy Resin . . . . . 197 H. G. Ehrlich Electron Microscopy of the Degeneration of Fine Structure in Saintpaulia ionantha Wendl. Pollen Walls . . . . . . 199 V. Defendi and D. Kritchevsky A Histoautoradiographic Study of Deoxyribonucleic Acid Synthesis in Tissue Cultures of Chicken Embryo Liver Cells Infected with RPL-12 Lymphomatosis Virus . . . . . . . . . . . . . . . . . 201
Marshall W. Hartley and W. H. McShan and Hans Ris Isolation of Cytoplasmic Pituitary Granules with Gonadotropic Activity . . 209 Virendra B. Kamat and Donald F. Hoelzl Wallach and John F. Crigler and Aaron J. Ladman The Intracellular Localization of Hormonal Activity in Transplantable Thyrotropin--Secreting Pituitary Tumors in Mice . . . . . . . . . . . . . . . . 219 Joe L. Griffin The Isolation, Characterization, and Identification of the Crystalline Inclusions of the Large Free--Living Amebae . . . . . . . . . . . . . . . . . 227 C. L. Greenblatt and R. A. Olson and E. K. Engel Absorption Microscopy of Enzymatically Treated Cell--Free Chloroplasts . . . . 235 Leonard Share and Ronald W. Hansrote Permeability of Rat Liver Microsomes to Sucrose and Carboxypoly-glucose in vitro 239 A. G. E. Pearse and D. G. Scarpelli and R. Hess A Cytochemical Study of the Dehydrogenases of Mitochondria and Mitochondrial Particulates by a Monotetrazolium--Cobalt Chelation Method 243 Tadao Mitsui Application of the Electron Microscope to the Cytochemical Peroxidase Reaction in Salamander Leukocytes . . . . . . . . 251 Marvin M. Nachlas and Benito Monis and David Rosenblatt and Arnold M. Seligman Improvement in the Histochemical Localization of Leucine Aminopeptidase with a New Substrate, L -Leucyl-4-Methoxy-2-Naphthylamide . . . 261 I. Leslie and Margaret Yarnell Succinic Dehydrogenase and Cytochrome Oxidase Activities in Cell Cultures . . 265 Joshua L. Edwards and Arthur L. Koch and Pauline Youcis and Herbert L. Freese and Melville B. Laite and J. Thomas Donalson Some Characteristics of DNA Synthesis and the Mitotic Cycle in Ehrlich Ascites Tumor Cells . . . . . . . . . . . . . . 273 T. Timothy Crocker and S. R. Pelc Incorporation and Rate of Loss of S$^{35}$-Methionine by Adult Rat Trachea in Organ Cultures and in Living Animals 283 Paul B. Green Multinet Growth in the Cell Wall of Nitella . . . . . . . . . . . . . . . . 289 Marilyn G. Farquhar and George E. Palade Segregation of Ferritin in Glomerular Protein Absorption Droplets . . . . . . 297 Tadayo Hashimoto and Philipp Gerhardt and S. F. Conti and H. B. Naylor Studies on the Fine Structure of Microorganisms . . . . . . . . . . . . . 305 William Zebrun and Hilton H. Mollenhauer Electron Microscopic Observations on Mitochondria of Rat Testes Fixed in Potassium Permanganate . . . . . . . . . 311 Laura Hunter Colwin and Arthur L. Colwin Formation of Sperm Entry Holes in the Vitelline Membrane of Hydroides hexagonus (Annelida) and Evidence of their Lytic Origin . . . . . . . . . . . 315 Arthur L. Colwin and Laura Hunter Colwin Egg Membrane Lytic Activity of Sperm Extract and its Significance in Relation to Sperm Entry in Hydroides hexagonus (Annelida) . . . . . . . . . . . . . . . 321 Edward Essner An Electron Microscopic Study of Erythrophagocytosis . . . . . . . . . . 329 Shimon Klein and B. Ginzburg An electron microscopic investigation into the effect of EDTA on plant cell wall . . . . . . . . . . . . . . . . . . 335 Arthur Hess The Fine Structure of Degenerating Nerve Fibers, their Sheaths, and their Terminations in the Central Nerve Cord of the Cockroach (\bionamePeriplaneta americana) . . . . . . . . . . . . . . . 339 Wallace H. Clark Electron Microscope Studies of Nuclear Extrusions in Pancreatic Acinar Cells of the Rat . . . . . . . . . . . . . . . . 345 E. H. Mercer and B. M. Shaffer Electron Microscopy of Solitary and Aggregated Slime Mould Cells . . . . . . 353 H. E. Karrer Electron Microscopic Study of the Phagocytosis Process in Lung . . . . . . 357 Juan D. Vial and Héctor Orrego Electron Microscope Observations on the Fine Structure of Parietal Cells . . . . 367 Pauline E. Holbert An Effective Method of Preparing Sections of Bacillus polymyxa Sporangia and Spores for Electron Microscopy . . . 373 Bernard R. Nebel and Sylvanus A. Tyler and Carol J. Murphy A Note on the Statistical Determination of Shape of Chromatin Elements in Human Spermatid and \bionameTradescantia Microsporocyte . . . . . . . . . . . . . 377 P. Borst Preparation and Properties of Mitochondria from Ehrlich Ascites Tumor Cells . . . . . . . . . . . . . . . . . 381 S. J. Holt and Eluned E. Hobbiger and G. L. S. Pawan Preservation of Integrity of Rat Tissues for Cytochemical Staining Purposes . . . 383 Elisabeth R. G. Mölbert and Franz Duspiva and Otto H. von Deimlimg The Demonstration of Alkaline Phosphatase in the Electron Microscope 387 Sanford L. Palay On the Appearance of Absorbed Fat Droplets in the Nuclear Envelope . . . . 391 P. Emmelot and E. L. Benedetti Changes in the Fine Structure of Rat Liver Cells Brought about by Dimethylnitrosamine . . . . . . . . . . 393 Leslie L. Franchi Electron Microscopy of Oocyte--Follicle Cell Relationships in the Rat Ovary . . 397 Par Roger Lavallard Étude au Microscope Électronique du Reticulum Endoplasmique dans des Fibres Musculaires du Crabe Bleu. (French) [Electroscopic Study of Endoplasmic Reticulum in Muscle Fibers of the Blue Crab] . . . . . . . . . . . . . . . . . 399 Robert A. Resnik and Theodor Wanko and Mary Ann Gavin Observations on a Cytoplasmic Component in Lens Fibers . . . . . . . . . . . . . 403 Eichi Yamada Collagen Fibrils within the Renal Glomerulus . . . . . . . . . . . . . . . 407 Albert J. Dalton and Robert F. Zeigel A Simplified Method of Staining Thin Sections of Biological Material with Lead Hydroxide for Electron Microscopy 409 Mitsugu Nishiura and S. R. S. Rangan A Device for Embedding Tissue Culture Preparations Grown on Coverslips . . . . 411
Steven L. Wissig The Anatomy of Secretion in the Follicular Cells of the Thyroid Gland 419 Susumu Ito The Lamellar Systems of Cytoplasmic Membranes in Dividing Spermatogenic Cells of \bionameDrosophila virilis . . 433 Jay S. Roth Studies on the Function of Intracellular Ribonucleases . . . . . . . . . . . . . 443 J. Herbert Taylor Asynchronous Duplication of Chromosomes in Cultured Cells of Chinese Hamster . . 455 Edward L. Kuff and Robert F. Zeigel Cytoplasmic Ribonucleoprotein Components of the Novikoff Hepatoma . . . . . . . . 465 Audrey M. Glauert and David A. Hopwood The Fine Structure of \bionameStreptomyces coelicolor . . . . 479 Michael L. Watson The Extracellular Nature of Enamel in the Rat . . . . . . . . . . . . . . . . 489 Arnaldo Lasansky and Eduardo de Robertis Electron Microscopy of Retinal Photoreceptors . . . . . . . . . . . . . 493 G. Yasuzumi and Hiroaki Tanaka and Osamu Tezuka Spermatogenesis in Animals as Revealed by Electron Microscopy . . . . . . . . . 499 David Brandes and Adolfo Portela The Fine Structure of the Epithelial Cells of the Mouse Prostate . . . . . . 505 David Brandes and Adolfo Portela The Fine Structure of the Epithelial Cells of the Mouse Prostate . . . . . . 511 David P. Bloch and Howard Y. C. Hew Schedule of Spermatogenesis in the Pulmonate Snail Helix aspersa, with Special Reference to Histone Transition 515 M. K. Keech Electron Microscope Study of the Normal Rat Aorta . . . . . . . . . . . . . . . 533 M. K. Keech Electron Microscope Study of the Lathyritic Rat Aorta . . . . . . . . . . 539 Y. Moulé and C. Rouiller and J. Chauveau A Biochemical and Morphological Study of Rat Liver Microsomes . . . . . . . . . . 547 Charles R. Capers Multinucleation of Skeletal Muscle in vitro . . . . . . . . . . . . . . . . . 559 D. Louise Odor Electron Microscopic Studies on Ovarian Oocytes and Unfertilized Tubal Ova in the Rat . . . . . . . . . . . . . . . . 567 Kiyoshi Hama The Fine Structure of the Desmosomes in Frog Mesothelium . . . . . . . . . . . . 575 Von W. Sandritter and H. G. Schiemer and H. Kraus and Und U. Dörrien Das Wachstum von Einzelzellen in der Gewebekultur. Interferenzmikroskopische Untersuchungen an HeLa--Zellen. (German) [The growth of single cells in tissue culture. Interference Microscopy investigation of HeLa Cells] . . . . . . 579 A. J. Shatkin A Chlorophyll--Containing Cell Fraction from the Blue--Green Alga, Anabaena variabilis . . . . . . . . . . . . . . . 583
Helmut Pauly and Lester Packer and H. P. Schwan Electrical Properties of Mitochondrial Membranes . . . . . . . . . . . . . . . 589 Helmut Pauly and Lester Packer The Relationship of Internal Conductance and Membrane Capacity to Mitochondrial Volume . . . . . . . . . . . . . . . . . 603 Cecil E. Hall Measurement of Globular Protein Molecules by Electron Microscopy . . . . 613 Philip Siekevitz and George E. Palade A Cytochemical Study on the Pancreas of the Guinea Pig . . . . . . . . . . . . . 619 Philip Siekevitz and George E. Palade A Cytochemical Study on the Pancreas of the Guinea Pig . . . . . . . . . . . . . 631 Burton Goldberg and Howard Green Immune Cytolysis . . . . . . . . . . . . 645 Nancy L. R. Bucher and Daniel Mazia Deoxyribonucleic Acid Synthesis in Relation to Duplication of Centers in Dividing Eggs of the Sea Urchin, Strongylocentrotus purpuratus . . . . . 651 Joseph G. Gall and William W. Johnson Is there ``Metabolic'' DNA in the Mouse Seminal Vesicle? . . . . . . . . . . . . 657 M. R. Loran and T. L. Althausen Cellular Proliferation of Intestinal Epithelia in the Rat Two Months after Partial Resection of the Ileum . . . . . 667 L. Weiss and J. A. Armstrong Structural Changes in Mammalian Cells Associated with Cooling to -79$^\circ $C 673 Arnaldo Lasansky and Eduardo De Robertis Submicroscopic Analysis of the Genetic Distrophy of Visual Cells in C3H Mice 679 Richard P. Bunge and Mary Bartlett Bunge and Hans Ris Electron Microscopic Study of Demyelination in an Experimentally Induced Lesion in Adult Cat Spinal Cord 685 I. R. Gibbons and A. V. Grimstone On Flagellar Structure in Certain Flagellates . . . . . . . . . . . . . . 697 Kiyoshi Hama The Fine Structure of Some Blood Vessels of the Earthworm, Eisenia foetida . . . 717 Neil C. R. Merrillees The Fine Structure of Muscle Spindles in the Lumbrical Muscles of the Rat . . . . 725 Erling Johansen and Harold F. Parks Electron Microscopic Observations on the Three--Dimensional Morphology of Apatite Crystallites of Human Dentine and Bone' 743 Etienne de Harven and Charlotte Friend Further Electron Microscope Studies of a Mouse Leukemia Induced by Cell--Free Filtrates . . . . . . . . . . . . . . . 747 Allan F. Howatson and June D. Almeida An Electron Microscope Study of Polyoma Virus in Hamster Kidney . . . . . . . . 753 Betty Geren Uzman and Gloria M. Villegas A Comparison of Nodes of Ranvier in Sciatic Nerves with Node--Like Structures in Optic Nerves of the Mouse 761
R. E. Burge and N. R. Silvester The Measurement of Mass, Thickness, and Density in the Electron Microscope . . . 1 J. B. Finean Electron Microscope and X-Ray Diffraction Studies of the Effects of Dehydration on the Structure of Nerve Myelin . . . . . . . . . . . . . . . . . 13 J. B. Finean Electron Microscope and X-Ray Diffraction Studies of the Effects of Dehydration on the Structure of Nerve Myelin . . . . . . . . . . . . . . . . . 31 Jan-Erik Edström Extraction, Hydrolysis, and Electrophoretic Analysis of Ribonucleic Acid from Microscopic Tissue Units (Microphoresis) . . . . . . . . . . . . 39 Jan-Erik Edström Composition of Ribonucleic Acid from Various Parts of Spider Oocytes . . . . 47 Charles N. Gamble and David Glick Studies in Histochemistry . . . . . . . 53 G. Adolph Ackerman Histochemical Demonstration of Dehydrogenase Activity in the Cells of Normal Human Blood and Bone Marrow . . . 61 David P. Bloch and Howard Y. C. Hew Changes in nuclear histones during fertilization, and early embryonic development in the pulmonate snail, \bionameHelix aspersa . . . . . . . . . 69 Russell J. Barrnett and Eric G. Ball Metabolic and Ultrastructural Changes Induced in Adipose Tissue by Insulin . . 83 David S. Smith and Virginia C. Littau Cellular specialization in the excretory epithelia of an insect, \bionameMacrosteles fascifrons stål (homoptera) . . . . . . . . . . . . . . 103 H. E. Karrer The Striated Musculature of Blood Vessels . . . . . . . . . . . . . . . . 135 Huntington Sheldon and Robert A. Robinson Studies on Cartilage . . . . . . . . . . 151 P. Drochmans Electron Microscope Studies of Epidermal Melanocytes, and the Fine Structure of Melanin Granules . . . . . . . . . . . . 165 Keith R. Porter and Eichi Yamada Studies on the Endoplasmic Reticulum . . 181 L. E. Roth and S. W. Obetz and E. W. Daniels Electron Microscopic Studies of Mitosis in Amebae . . . . . . . . . . . . . . . 207 Irene Manton On a reticular derivative from Golgi bodies in the meristem of \bionameAnthoceros . . . . . . . . . . . 221 W. Gordon Whaley and Hilton H. Mollenhauer and James H. Leech Some Observations on the Nuclear Envelope . . . . . . . . . . . . . . . . 233 Jerome M. Aronson and R. D. Preston The microfibrillar structure of the cell walls of the filamentous fungus, \bionameAllomyces . . . . . . . . . . . 247 David A. Hopwood and Audrey M. Glauert Observations on the chromatinic bodies of \bionameStreptomyces coelicolor . . . 257 David A. Hopwood and Audrey M. Glauert The fine structure of \bionameStreptomyces coelicolor . . . . 267 Mikko Niemi and A. G. E. Pearse The Relationship of the Mitochondria to Egg White Absorption Droplets in Rat Kidney . . . . . . . . . . . . . . . . . 279 E. G. Gray Regular Organisation of Material in Certain Mitochondria of Neuroglia of Lizard Brain . . . . . . . . . . . . . . 282 Tosisuke Hiraoka Electrophoretic Analysis of Colored Product Produced by Schiff-Formaldehyde Reaction . . . . . . . . . . . . . . . . 286 Cicily Chapman-Andresen and Howard Holtzer The uptake of fluorescent albumin by pinocytosis in \bionameAmoeba proteus 288 O. Núñez-Montiel and J. Weibel Electron Microscope Study of Echo 19 Virus Infection in Monkey Kidney Cells 291
Philip M. Grimley and George A. Edwards The Ultrastructure of Cardiac Desmosomes in the Toad and Their Relationship to the Intercalated Disc . . . . . . . . . 305 Morris J. Karnovsky and Gerald D. Fasman A histochemical method for distinguishing between side-chain and terminal ($ \alpha $-acylamido) carboxyl groups of proteins . . . . . . . . . . . 319 Donald E. Wimber and Henry Quastler and Otto L. Stein and Doris R. Wimber Analysis of Tritium Incorporation into Individual Cells by Autoradiography of Squash Preparations . . . . . . . . . . 327 Irwin R. Konigsberg and Norma McElvain and Martha Tootle and Heinz Herrmann The Dissociability of Deoxyribonucleic Acid Synthesis from the Development of Multinuclearity of Muscle Cells in Culture . . . . . . . . . . . . . . . . 333 Harold P. Klinger and Hans G. Schwarzacher The Sex Chromatin and Heterochromatic Bodies in Human Diploid and Polyploid Nuclei . . . . . . . . . . . . . . . . . 345 Rachel McMaster-Kaye The Metabolic Characteristics of Nucleolar, Chromosomal, and Cytoplasmic Ribonucleic Acid of \bionameDrosophila Salivary Glands . . . . . . . . . . . . 365 Robert D. Allen The Consistency of Ameba Cytoplasm and Its Bearing on the Mechanism of Ameboid Movement . . . . . . . . . . . . . . . . 379 Antoinette Ryter Étude au microscope électronique des transformations nucléaires de \bionameE. coli K12S et K12S$ (\lambda_{26}) $ apr\`es irradiation aux rayons ultraviolets et aux rayons X . . . . . . 399 David M. Neville The Isolation of a Cell Membrane Fraction from Rat Liver . . . . . . . . 413 George G. Rose and C. M. Pomerat Phase Contrast Observations of the Endoplasmic Reticulum in Living Tissue Cultures . . . . . . . . . . . . . . . . 423 A. Peters The Formation and Structure of Myelin Sheaths in the Central Nervous System 431 David S. Smith Innervation of the Fibrillar Flight Muscle of an Insect: Tenebrio Molitor (Coleoptera) . . . . . . . . . . . . . . 447 Nikolajs Cauna and Leonard L. Ross The fine structure of Meissner's touch corpuscles of human fingers . . . . . . 467 Richard M. Eakin and Jane A. Westfall Further Observations on the Fine Structure of the Parietal Eye of Lizards 483 Peter Albersheim and K. Mühlethaler and A. Frey-Wyssling Stained Pectin As Seen in the Electron Microscope . . . . . . . . . . . . . . . 501 Philip C. Fitz-James Participation of the Cytoplasmic Membrane in the Growth and Spore Formation of Bacilli . . . . . . . . . . 507 Shimon Klein The Effect of Low Temperature on the Development of the Lamellar System in Chloroplasts . . . . . . . . . . . . . . 529 H. R. Munden A Set of Collets for Manipulating the Specimen Holder of the Siemens Electron Microscope . . . . . . . . . . . . . . . 541 M. Steinert Mitochondria Associated with the Kinetonucleus of Trypanosoma Mega . . . 542 R. Hess and F. M. Dietrich Cytochemical Localization of Dehydrogenase and Diaphorase Activity in Bacillus Megaterium . . . . . . . . . . 546 R. C. King and Gretchen J. Falk In Vitro Incorporation of Uridine-H$^3$ into Developing Fruit Fly Oocytes . . . 550 P. Drochmans Mise En ÉVidence Du GlycogÉNe Dans La Cellule HÉPatique Par Microscopie ÉLectronique . . . . . . . . . . . . . . 553 S. Wischnitzer Observations on the Annulate Lamellae of Immature Amphibian Oocytes . . . . . . . 558 M. Steinert and A. B. Novikoff The Existence of a Cytostome and the Occurrence of Pinocytosis in the Trypanosome, Trypanosoma Mega . . . . . 563
Jean Paul Revel and Leonard Napolitano and Don W. Fawcett Identification of Glycogen in Electron Micrographs of Thin Tissue Sections . . 575 Irving Finger and Michael Kaback and Philip Kittner and Carol Heller Immunological Studies of Isolated Particulates of Paramecium Aurelia . . . 591 Hikoichi Sakai Studies on Sulfhydryl Groups During Cell Division of Sea Urchin Egg . . . . . . . 603 Hikoichi Sakai Studies on Sulfhydryl Groups During Cell Division of Sea Urchin Egg . . . . . . . 609 Satimaru Seno and K\=oy\=o Yoshizawa Electron Microscope Observations on Frozen-Dried Cells . . . . . . . . . . . 617 Stanley Bullivant The Staining of Thin Sections of Mouse Pancreas Prepared by the FernÁNdez--MorÁN Helium Ii Freeze-Substitution Method . . 639 Norwin H. Becker and Sidney Goldfischer and Woo-Yung Shin and Alex B. Novikoff The Localization of Enzyme Activities in the Rat Brain . . . . . . . . . . . . . 649 Jay S. Roth Studies on the Function of Intracellular Ribonucleases . . . . . . . . . . . . . 665 Philip W. Brandt and George D. Pappas An Electron Microscopic Study of Pinocytosis in Ameba . . . . . . . . . . 675 Fritz Miller Hemoglobin Absorption by the Cells of the Proximal Convoluted Tubule in Mouse Kidney . . . . . . . . . . . . . . . . . 689 Gabriel C. Godman and Keith R. Porter Chondrogenesis, Studied with the Electron Microscope . . . . . . . . . . 719 Hilton H. Mollenhauer and William Zebrun Permanganate Fixation of the Golgi Complex and Other Cytoplasmic Structures of Mammalian Testes . . . . . . . . . . 761 Marcel Bessis and Georges Nomarski Irradiation Ultra-Violette Des Organites Cellulaires Avec Observation Continue En Contraste De Phase . . . . . . . . . . . 777 H. W. Beams and T. N. Tahmisian and Everett Anderson and Rosemarie Devine Studies on the Fine Structure of Ultracentrifuged Spinal Ganglion Cells 793 David A. Hopwood and Audrey M. Glauert The Fine Structure of the Nuclear Material of a Blue-Green Alga, Anabaena Cylindrica Lemm . . . . . . . . . . . . 813 Erland Nelson and Hermann Hager and Ernest Kovács Intracellular Virus Crystals in the Central Nervous System of Mice Following Rodent Polioencephalitis (Mm Strain) Infection . . . . . . . . . . . . . . . 825 A. F. Howatson and J. D. Almeida Observations on the Fine Structure of Polyoma Virus . . . . . . . . . . . . . 828 D. F. Parsons and E. B. Darden A Technique for the Simultaneous Dirt-Free Lead Staining of Several Electron Microscope Grids of Thin Sections . . . . . . . . . . . . . . . . 834 Robert Hadek and Hewson Swift A Crystalloid Inclusion in the Rabbit Blastocyst . . . . . . . . . . . . . . . 836
Albert W. Sedar Electron Microscopy of the Oxyntic Cell in the Gastric Glands of the Bullfrog (\bionameRana Catesbiana) . . . . . . . 1 Ronald W. Estabrook and Andrew Holowinsky Studies on the Content and Organization of the Respiratory Enzymes of Mitochondria . . . . . . . . . . . . . . 19 T. N. Tahmisian and R. L. Devine The Influence of X-Rays on Organelle Induction and Differentiation in Grasshopper Spermatogenesis . . . . . . 29 Alex B. Novikoff and Woo-Yung Shin and Joan Drucker Mitochondrial Localization of Oxidative Enzymes: Staining Results with Two Tetrazolium Salts . . . . . . . . . . . 47 Hans Ris and R. N. Singh Electron Microscope Studies on Blue-Green Algae . . . . . . . . . . . . 63 Ellen Borenfreund and Aaron Bendich A Study of the Penetration of Mammalian Cells by Deoxyribonucleic Acids . . . . 81 Jane Couffer-Kaltenbach and Peter Perlmann Antigens in Eggs and Developmental Stages of the Sea Urchin . . . . . . . . 93 David D. Sabatini and Eduardo D. P. De Robertis Ultrastructural Zonation of Adrenocortex in the Rat . . . . . . . . . . . . . . . 105 Vittorio Marinozzi Silver Impregnation of Ultrathin Sections for Electron Microscopy . . . . 121 Klaus G. Bensch and Donald W. King and Edward L. Socolow The Source of Lipid Accumulation in L Cells . . . . . . . . . . . . . . . . . 135 Cosmo G. Mackenzie and Julia B. Mackenzie and Paul Beck The effect of pH on growth, protein synthesis, and lipid-rich particles of cultured mammalian cells . . . . . . . . 141 Fritz Miller Lipoprotein Granules in the Cortical Collecting Tubules of Mouse Kidney . . . 157 Woutera Van Iterson and C. F. Robinow Observations with the Electron Microscope on the Fine Structure of the Nuclei of Two Spherical Bacteria . . . . 171 Woutera Van Iterson Some Features of a Remarkable Organelle in \bionameBacillus Subtilis . . . . . . 183 M. K. Keech The Formation of Fibrils from Collagen Solutions . . . . . . . . . . . . . . . 193 J. E. Shapiro and B. R. Hershenov and G. S. Tulloch The Fine Structure of \bionameHaematol\oechus Spermatozoan Tail . . . . . . . . . . . . . . . . . . 211 R. F. Baker and H. E. Pearson New Embedding Method for Cell Suspensions . . . . . . . . . . . . . . 217 R. P. van Tubergen The Use of Radioautography and Electron Microscopy for the Localization of Tritium Label in Bacteria . . . . . . . 219 Montrose J. Moses Spermiogenesis in the Crayfish (\bionameProcambarus Clarkii) . . . . . 222 E. De Robertis and A. Pellegrino De Iraldi and Georgina Rodriguez and C. J. Gomez On the Isolation of Nerve Endings and Synaptic Vesicles . . . . . . . . . . . 229 A. Policard and A. Collet and H. Daniel-Moussard and S. Pregermain Deposition of Silica in Mitochondria: an Electron Microscopic Study . . . . . . . 236 Richard A. Ellis and William Montagna Electron Microscopy of the Duct, and Especially the ``Cuticular Border'' of the Eccrine Sweat Glands in Macaca Mulatta . . . . . . . . . . . . . . . . 238 Gerald R. Seaman Acid Phosphatase Activity Associated with Phagotrophy in the Ciliate, \bionameTetrahymena . . . . . . . . . . 243
D. Danon and Y. Marikovsky and U. Z. Littauer A Comparative Electron Microscopical Study of RNA from Different Sources . . 253 Goetz W. Richter Intranuclear Aggregates of Ferritin in Liver Cells of Mice Treated with Saccharated Iron Oxide . . . . . . . . . 263 Herbert Stern Periodic Induction of Deoxyribonuclease Activity in Relation to the Mitotic Cycle . . . . . . . . . . . . . . . . . 271 Yasuo Hotta and Herbert Stern Deamination of Deoxycytidine and $5$-Methyldeoxycytidine in Developing Anthers of Lilium Longiflorum (Var. Croft) . . . . . . . . . . . . . . . . . 279 Christopher L. Hannay Fowler's Bacillus and Its Parasporal Body . . . . . . . . . . . . . . . . . . 285 Federico Gonzales and Morris J. Karnovsky Electron Microscopy of Osteoclasts in Healing Fractures of Rat Bone . . . . . 299 L. E. Roth and E. W. Daniels Infective Organisms in the Cytoplasm of Amoeba Proteus . . . . . . . . . . . . . 317 Richard J. Stenger and David Spiro The Ultrastructure of Mammalian Cardiac Muscle . . . . . . . . . . . . . . . . . 325 D. F. Parsons and E. B. Darden and D. L. Lindsley and Guthrie T. Pratt Electron Microscopy of Plasma-Cell Tumors of the Mouse . . . . . . . . . . 353 D. F. Parsons and M. A. Bender and E. B. Darden and Guthrie T. Pratt and D. L. Lindsley Electron Microscopy of Plasma-Cell Tumors of the Mouse . . . . . . . . . . 369 Björn A. Afzelius The Fine Structure of the Cilia from Ctenophore Swimming-Plates . . . . . . . 383 Charles Grégoire Structure of the Conchiolin Cases of the Prisms in Mytilus Edulis Linne . . . . . 395 Robert D. Campo and Dominic D. Dziewiatkowski A Consideration of the Permeability of Cartilage to Inorganic Sulfate . . . . . 401 John H. Luft Improvements in Epoxy Resin Embedding Methods . . . . . . . . . . . . . . . . 409 Donald G. Walker and Arnold M. Seligman Formalin Fixation in the Cytochemical Demonstration of Succinic Dehydrogenase of Mitochondria . . . . . . . . . . . . 415 Richard M. Condie and A. Ervin Howell and Robert A. Good Studies on the Problem of Preservation of Myelin Sheath Ultrastructure: Evaluation of Fixation, Dehydration, and Embedding Techniques . . . . . . . . . . 429 John Woodard and Ellen Rasch and Hewson Swift Nucleic Acid and Protein Metabolism During the Mitotic Cycle in \bionameVicia Faba . . . . . . . . . . . 445 George G. Rose The Golgi Complex in Living Osteoblasts 463 S. R. Wellings and K. B. Deome Milk protein droplet formation in the Golgi apparatus of the C3H/Crgl mouse mammary epithelial cells . . . . . . . . 479 R. Bruce Nicklas The Relationship Between DNA Content and Alternative Meiotic Patterns in Certain Discocephalinids (Pentatomidae; Heteroptera) . . . . . . . . . . . . . . 486 E. J. Batham Infoldings of Nerve Fibre Membranes in the Opisthobranch Mollusc \bionameAplysia Californica . . . . . . 490 Alexander Mauro Satellite Cell of Skeletal Muscle Fibers 493 Kenji Takeya and Ryoichi Mori and Tooru Tokunaga and Masaatsu Koike and Kazuhito Hisatsune Further Studies on the Paired Fibrous Structure of Mycobacterial Cell Wall . . 496 E. J. Harris The Site of Swelling in Muscle . . . . . 502
Jesse E. Sisken and Riojun Kinosita Timing of DNA Synthesis in the Mitotic Cycle in Vitro . . . . . . . . . . . . . 509 S. J. Singer and Anita F. Schick The Properties of Specific Stains for Electron Microscopy Prepared by the Conjugation of Antibody Molecules with Ferritin . . . . . . . . . . . . . . . . 519 Lucien G. Caro Localization of Macromolecules in \bionameEscherichia coli . . . . . . . . 539 Lucien G. Caro and Frederick Forro Localization of Macromolecules in \bionameEscherichia coli . . . . . . . . 555 M. T. M. Rizki Intracellular Localization of Kynurenine in the Fatbody of \bionameDrosophila . . 567 S. Ralph Himmelhoch and Morris J. Karnovsky The Histochemical Demonstration of Glyceraldehyde-$3$-Phosphate Dehydrogenase Activity . . . . . . . . . 573 D. A. Cameron The Fine Structure of Osteoblasts in the Metaphysis of the Tibia of the Young Rat 583 Masaatsu Koike and Kenji Takeya Fine Structures of Intracytoplasmic Organelles of Mycobacteria . . . . . . . 597 M. Zalokar Electron Microscopy of Centrifuged Hyphae of Neurospora . . . . . . . . . . 609 Jan-Erik Edström and Jerzy Kawiak Microchemical Deoxyribonucleic Acid Determination in Individual Cells . . . 619 Abraham M. Breslau and Thomas J. Hensley and John O. Erickson Electron Microscopy of Cultured Spherules of Coccidioides Immitis . . . 627 J. A. Chapman Morphological and Chemical Studies of Collagen Formation . . . . . . . . . . . 639 A. Kent Christensen and Don W. Fawcett The Normal Fine Structure of Opossum Testicular Interstitial Cells . . . . . 653 Howard G. Davies Structure in Nucleated Erythrocytes . . 671 Eberhards Vitols and R. J. North and Anthony W. Linnane Studies on the Oxidative Metabolism of \bionameSaccharomyces Cerevisiae . . . . 689 Eberhards Vitols and Anthony W. Linnane Studies on the Oxidative Metabolism of \bionameSaccharomyces Cerevisiae . . . . 701 Bruce K. Wetzel Sodium Permanganate Fixation for Electron Microscopy . . . . . . . . . . 711 M. T. Jansen and I. Molenaar Ultraviolet Microscopy of Pancreatic Acinar Nuclei Fixed in Potassium Permanganate . . . . . . . . . . . . . . 716 J. J. Wolken and P. D. Gupta Photoreceptor Structures. the Retinal Cells of the Cockroach Eye . . . . . . . 720 Barbara G. Barnes and T. C. Chambers A Simple and Rapid Method for Mounting Serial Sections for Electron Microscopy 724 David Danon An Instrument to Trim Plastic Specimen Blocks for Electron Microscopy Prior to Sectioning . . . . . . . . . . . . . . . 726
Morris Belkin and Walter G. Hardy Relation Between Water Permeability and Integrity of Sulfhydryl Groups in Malignant and Normal Cells . . . . . . . 733 William H. Telfer The Route of Entry and Localization of Blood Proteins in the Oocytes of Saturniid Moths . . . . . . . . . . . . 747 Norimitsu Watabe and Karl M. Wilbur Studies on Shell Formation . . . . . . . 761 E. Essner and Alex B. Novikoff Localization of Acid Phosphatase Activity in Hepatic Lysosomes by Means of Electron Microscopy . . . . . . . . . 773 Lionel I. Rebhun Applications of Freeze-Substitution to Electron Microscope Studies of Invertebrate Oocytes . . . . . . . . . . 785 Albert I. Lansing and Francois Lamy Fine Structure of the Cilia of Rotifers 799 Edgar A. Tonna The Cellular Complement of the Skeletal System Studied Autoradiographically with Tritiated Thymidine (H$^3$ Tdr) During Growth and Aging . . . . . . . . . . . . 813 Edward J. Reith The Ultrastructure of Ameloblasts During Matrix Formation and the Maturation of Enamel . . . . . . . . . . . . . . . . . 825 G. H. Haggis Electron Microscope Replicas from the Surface of a Fracture Through Frozen Cells . . . . . . . . . . . . . . . . . 841 Jack Rosenbluth and Sanford L. Palay The Fine Structure of Nerve Cell Bodies and Their Myelin Sheaths in the Eighth Nerve Ganglion of the Goldfish . . . . . 853 C. F. Robinow Mitosis in the Yeast Lipomyces Lipofer 879 S. Ralph Himmelhoch and Morris J. Karnovsky Oxidative and Hydrolytic Enzymes in the Nephron of Necturus Maculosus . . . . . 893 Heather Donald Mayor and James C. Hampton and Benjamin Rosario A Simple Method for Removing the Resin from Epoxy-Embedded Tissue . . . . . . . 909 Walter G. Rosen and Kenneth A. Siegesmund Some Observations on the Fine Structure of a Thermophilic, Acidophilic Alga . . 910 Carolyn G. Smoller and Dorothy R. Pitelka and Howard A. Bern Cytoplasmic inclusion bodies in cortisol--treated mammary tumors of C3H/Crgl mice . . . . . . . . . . . . . 915
H. Moor and K. Mühlethaler and H. Waldner and A. Frey-Wyssling A New Freezing-Ultramicrotome . . . . . 1 Gerald S. Gotterer and Thomas E. Thompson and Albert L. Lehninger Angular Light-Scattering Studies on Isolated Mitochondria . . . . . . . . . 15 Joseph C. Arcos and Hans H. Gosch and David Zickafoose Fine Structural Alterations in Cell Particles During Chemical Carcinogenesis 23 Lucien G. Caro Electron Microscopic Radioautography of Thin Sections: the Golgi Zone As a Site of Protein Concentration in Pancreatic Acinar Cells . . . . . . . . . . . . . . 37 Albert W. Sedar Electron Microscopy of the Oxyntic Cell in the Gastric Glands of the Bullfrog, Rana Catesbiana . . . . . . . . . . . . 47 Eva B. Simmel and David A. Karnofsky Observations on the Uptake of Tritiated Thymidine in the Pronuclei of Fertilized Sand Dollar Embryos . . . . . . . . . . 59 Mary Bartlett Bunge and Richard P. Bunge and Hans Ris Ultrastructural Study of Remyelination in an Experimental Lesion in Adult Cat Spinal Cord . . . . . . . . . . . . . . 67 T. S. Leeson and H. Kalant Effects of in Vivo Decalcification on Ultrastructure of Adult Rat Liver . . . 95 M. Rabinovitch and R. Brentani and S. Ferreira and N. Fausto and T. Maack Alkaline Ribonuclease Activity Increase in Rat Kidney Cortex and Liver After Trypan Blue and Other Azo Dyes Administration . . . . . . . . . . . . . 105 S. N. Chatterjee and P. Sadhukhan and J. B. Chatterjea Electron Microscope Studies on the Haemoglobin Molecules . . . . . . . . . 113 G. A. Meek and M. J. Moses Microtubulation of the Inner Membrane of the Nuclear Envelope . . . . . . . . . . 121 James H. McAlear and George Camougis and Lloyd F. Thibodeau Mapping of Large Areas with the Electron Microscope . . . . . . . . . . . . . . . 133 N. W. Wakid and Dorothy M. Needham Effect of Estradiol Injection on the Cytoplasmic Fractions of the Myometrium in the Ovariectomized Rat . . . . . . . 136 James C. Hampton and Henry Quastler Combined Autoradiography and Electron Microscopy of Thin Sections of Intestinal Epithelial Cells of the Mouse Labeled with H$^3$-Thymidine . . . . . . 140 Clinton B. Lillibridge Membranes of the Human Pepsinogen Granule . . . . . . . . . . . . . . . . 145
M. A. Epstein Some Unusual Features of Fine Structure Observed in HeLa Cells . . . . . . . . . 153 Joseph G. Gall Centriole Replication . . . . . . . . . 163 David J. L. Luck Glycogen Synthesis from Uridine Diphosphate Glucose . . . . . . . . . . 195 Arthur L. Colwin and Laura Hunter Colwin Fine Structure of the Spermatozoon of Hydroides Hexagonus (Annelida), with Special Reference to the Acrosomal Region . . . . . . . . . . . . . . . . . 211 Laura Hunter Colwin and Arthur L. Colwin Changes in the Spermatozoon During Fertilization in Hydroides Hexagonus (Annelida) . . . . . . . . . . . . . . . 231 Arthur L. Colwin and Laura Hunter Colwin Changes in the Spermatozoon During Fertilization in Hydroides Hexagonus (Annelida) . . . . . . . . . . . . . . . 255 Daniel G. Szollosi and Hans Ris Observations on Sperm Penetration in the Rat . . . . . . . . . . . . . . . . . . 275 Albert Wollenberger and Wolfgang Schulze Mitochondrial Alterations in the Myocardium of Dogs with Aortic Stenosis 285 B. Shannon Danes and Mary Struthers The Influence of Iron-Dextran Complex on the Strain L Fibroblast . . . . . . . . 289 Atsushi Suganuma The Plasma Membrane of Staphylococcus Aureus . . . . . . . . . . . . . . . . . 292
Montrose J. Moses Spermiogenesis in the Crayfish (\bionameProcambarus Clarkii) . . . . . 301 C. Richard Zobel and Michael Beer Electron Stains . . . . . . . . . . . . 335 Cecil E. Hall and Liebe F. Cavalieri Four-Stranded DNA As Determined by Electron Microscopy . . . . . . . . . . 347 G. W. Salisbury and W. J. Birge and L. de la Torre and J. R. Lodge Decrease in Nuclear Feulgen-Positive Material (DNA) Upon Aging in In Vitro Storage of Bovine Spermatozoa . . . . . 353 Eduardo De Robertis and Amanda Pellegrino de Iraldi Plurivesicular Secretory Processes and Nerve Endings in the Pineal Gland of the Rat . . . . . . . . . . . . . . . . . . 361 D. A. Lowther and N. M. Green and J. A. Chapman Morphological and Chemical Studies of Collagen Formation . . . . . . . . . . . 373 Richard Holmes and Sonya W. Wolfe Serum Fractionation and the Effects of Bovine Serum Fractions on Human Cells Grown in a Chemically Defined Medium . . 389 Endre Egyházi and Holger Hydén Experimentally Induced Changes in the Base Composition of the Ribonucleic Acids of Isolated Nerve Cells and Their Oligodendroglial Cells . . . . . . . . . 403 W. S. Morgan and P. Perlmann and T. Hultin Autoradiographic Analysis on Agar Plates of Antigens from Sub Cellular Fractions of Rat Liver Slices . . . . . . . . . . 411 George B. Chapman and Alden B. Dawson Fine Structure of the Larval Anuran Epidermis, with Special Reference to the Figures of Eberth . . . . . . . . . . . 425 Elizabeth H. Leduc and Wilhelm Bernhard Ultrastructural Cytochemistry . . . . . 437 Elizabeth D. Hay Fine Structure of an Unusual Intracellular Supporting Network in the Leydig Cells of Amblystoma Epidermis . . 457
Emilio Veratti Investigations on the Fine Structure of Striated Muscle Fiber . . . . . . . . . 1 David S. Smith Reticular Organizations Within the Striated Muscle Cell . . . . . . . . . . 61 Don W. Fawcett and Jean Paul Revel The Sarcoplasmic Reticulum of a Fast-Acting Fish Muscle . . . . . . . . 89 James F. Reger The Fine Structure of Neuromuscular Junctions and the Sarcoplasmic Reticulum of Extrinsic Eye Muscles of Fundulus Heteroclitus . . . . . . . . . . . . . . 111 David S. Smith The Structure of Insect Fibrillar Flight Muscle . . . . . . . . . . . . . . . . . 123 Lee D. Peachey Structure of the Longitudinal Body Muscles of Amphioxus . . . . . . . . . . 159 Alexander Mauro and W. Robert Adams The Structure of the Sarcolemma of the Frog Skeletal Muscle Fiber . . . . . . . 177 C. R. Skoglund Functional Analysis of Swim-Bladder Muscles Engaged in Sound Production of the Toadfish . . . . . . . . . . . . . . 187 U. Muscatello and Ebba Andersson-Cedergren and G. F. Azzone and Alexandra von der Decken The Sarcotubular System of Frog Skeletal Muscle . . . . . . . . . . . . . . . . . 201 Keith R. Porter The Sarcoplasmic Reticulum . . . . . . . 219 Daniel Mazia and J. M. Mitchison and Heitor Medina and Patricia Harris The Direct Isolation of the Mitotic Apparatus . . . . . . . . . . . . . . . 467 S. Dales and L. Siminovitch The Development of Vaccinia Virus in Earle's L Strain Cells As Examined by Electron Microscopy . . . . . . . . . . 475 Audrey M. Glauert and David A. Hopwood The Fine Structure of \bionameStreptomyces Violaceoruber (\bionameS. Coelicolor) . . . . . . . . 505 S. I. Zacks and J. M. Blumberg Observations on the Fine Structure and Cytochemistry of Mouse and Human Intercostal Neuromuscular Junctions . . 517 Lee D. Peachey and Howard Rasmussen Structure of the Toad's Urinary Bladder As Related to Its Physiology . . . . . . 529 Orville Wyss and Marilyn G. Neumann and M. D. Socolofsky Development and Germination of the Azotobacter Cyst . . . . . . . . . . . . 555 John J. Callaghan and Paul Grun Incorporation of C$^{14}$-Labeled Maleic Hydrazide into the Root-Tip Cells of \bionameAllium Cernuum, \bionameVicia Faba, and \bionameTradescantia Paludosa 567 M. H. Silk and A. O. Hawtrey and I. M. Spence and J. H. S. Gear A Method for Intracellular Autoradiography in the Electron Microscope . . . . . . . . . . . . . . . 577 Michael Locke Pore Canals and Related Structures in Insect Cuticle . . . . . . . . . . . . . 589
R. P. Perry Kinetics of Nucleoside Incorporation into Nuclear and Cytoplasmic RNA . . . . 1 Richard S. Thomas and Robley C. Williams Localization of DNA and Protein in Tipula Iridescent Virus (Tiv) by Enzymatic Digestion and Electron Microscopy . . . . . . . . . . . . . . . 15 S. J. Holt and R. Marian Hicks Studies on Formalin Fixation for Electron Microscopy and Cytochemical Staining Purposes . . . . . . . . . . . 31 S. J. Holt and R. Marian Hicks The Localization of Acid Phosphatase in Rat Liver Cells As Revealed by Combined Cytochemical Staining and Electron Microscopy . . . . . . . . . . . . . . . 47 Bernard Tunik and Howard Holtzer The Distribution of Muscle Antigens in Contracted Myofibrils Determined by Fluorescein-Labeled Antibodies . . . . . 67 P. D. Deshpande and D. D. Hickman and R. W. Von Korff Morphology of Isolated Rabbit Heart Muscle Mitochondria and the Oxidation of Extramitochondrial Reduced Diphosphopyridine Nucleotide . . . . . . 77 F. Carlsen and G. G. Knappeis and F. Buchthal Ultrastructure of the Resting and Contracted Striated Muscle Fiber at Different Degrees of Stretch . . . . . . 95 David S. Smith The Organization of the Flight Muscle in a Dragonfly, Aeshna Sp. (Odonata) . . . 119 John Aronson Sarcomere Size in Developing Muscles of a Tarsonemid Mite . . . . . . . . . . . 147 R. Price Peterson and Frank A. Pepe The Fine Structure of Inhibitory Synapses in the Crayfish . . . . . . . . 157 Seizo Tsuda and E. L. Tatum Intracellular Crystalline Ergosterol in Neurospora . . . . . . . . . . . . . . . 171 I. R. Gibbons The Relationship Between the Fine Structure and Direction of Beat in Gill Cilia of a Lamellibranch Mollusc . . . . 179 Ruth Bellairs The Structure of the Yolk of the Hen's Egg As Studied by Electron Microscopy 207 Robert C. Buck Lamellae in the Spindle of Mitotic Cells of Walker 256 Carcinoma . . . . . . . . 227 Arnaldo Lasansky Morphological Bases for a Nursing Role of Glia in the Toad Retina. Electron Microscope Observations . . . . . . . . 237 E. Roter Dirksen The Presence of Centrioles in Artificially Activated Sea Urchin Eggs 244 Harrison Latta and Arvid B. Maunsbach and Sidney C. Madden Cilia in Different Segments of the Rat Nephron . . . . . . . . . . . . . . . . 248
Michael L. Watson and William G. Aldridge Methods for the Use of Indium As an Electron Stain for Nucleic Acids . . . . 257 H. E. Huxley and G. Zubay Preferential Staining of Nucleic Acid-Containing Structures for Electron Microscopy . . . . . . . . . . . . . . . 273 Walther Stoeckenius Electron Microscopy of DNA Molecules ``Stained'' with Heavy Metal Salts . . . 297 Yasuo Hotta and Herbert Stern Transient Phosphorylation of Deoxyribosides and Regulation of Deoxyribonucleic Acid Synthesis . . . . 311 R. E. Monro Serological Studies on the Formation of Protein Parasporal Inclusions in Bacillus Thuringiensis . . . . . . . . . 321 Susumu Ito The Endoplasmic Reticulum of Gastric Parietal Cells . . . . . . . . . . . . . 333 A. W. Sedar and M. H. F. Friedman Correlation of the Fine Structure of the Gastric Parietal Cell (Dog) with Functional Activity of the Stomach . . . 349 Joseph D. Feldman and Jacinto J. Vazquez and Stanley M. Kurtz Maturation of the Rat Fetal Thyroid . . 365 Bryce L. Munger The Ultrastructure and Histophysiology of Human Eccrine Sweat Glands . . . . . 385 Bryce L. Munger and Saul W. Brusilow An Electron Microscopic Study of Eccrine Sweat Glands of the Cat Foot and Toe Pads --- Evidence for Ductal Reabsorption in the Human . . . . . . . 403 Patricia Harris Electron Microscope Study of Mitosis in Sea Urchin Blastomeres . . . . . . . . . 419 Shimon Klein and A. Poljakoff-Mayber Fine Structure and Pigment Conversion in Isolated Etiolated Proplastids . . . . . 433 Kenji Takeya and Masaatsu Koike and Ryoichi Mori and Tadao Toda Light and Electron Microscope Studies of Mycobacterium --- Mycobacteriophage Interactions . . . . . . . . . . . . . . 441 Elliott Robbins Some Theoretical Aspects of Osmium Tetroxide Fixation with Special Reference to the Metaphase Chromosomes of Cell Cultures . . . . . . . . . . . . 449 O. Núñez-Montiel and J. Weibel and J. Vitelli-Flores Electron Microscopic Study of the Cytopathology of Echo Virus Infection in Cultivated Cells . . . . . . . . . . . . 457 Edwin S. Boatman and Howard C. Douglas Fine Structure of the Photosynthetic Bacterium Rhodomicrobium Vannielii . . . 469 Robert B. Painter Asynchronous Replication of HeLa S3 Chromosomal Deoxyribonucleic Acid . . . 485 Arthur J. Hale Historadiographic Identification of Alkaline Phosphatase . . . . . . . . . . 488 D. F. Parsons A Simple Method for Obtaining Increased Contrast in Araldite Sections by Using Postfixation Staining of Tissues with Potassium Permanganate . . . . . . . . . 492 Albert I. Lansing and François Lamy Localization of ATP Ase in Rotifer Cilia 498 Bryce L. Munger Staining Methods Applicable to Sections of Osmium-Fixed Tissue for Light Microscopy . . . . . . . . . . . . . . . 502
Mortimer L. Mendelsohn The Two-Wavelength Method of Microspectrophotometry . . . . . . . . . 509 Frank A. Pepe The Use of Specific Antibody in Electron Microscopy . . . . . . . . . . . . . . . 515 Frank A. Pepe and H. Finck The Use of Specific Antibody in Electron Microscopy . . . . . . . . . . . . . . . 521 Frank A. Pepe and H. Finck and H. Holtzer The Use of Specific Antibody in Electron Microscopy . . . . . . . . . . . . . . . 533 Jan-Erik Edström and Wolfgang Grampp and Norberto Schor The Intracellular Distribution and Heterogeneity of Ribonucleic Acid in Starfish Oocytes . . . . . . . . . . . . 549 R. W. Merriam On the Fine Structure and Composition of the Nuclear Envelope . . . . . . . . . . 559 G. Majno and G. E. Palade Studies on Inflammation . . . . . . . . 571 G. Majno and G. E. Palade and Gutta I. Schoefl Studies on Inflammation . . . . . . . . 607 H. Robert Dudley and David Spiro The Fine Structure of Bone Cells . . . . 627 N. M. Hancox and B. Boothroyd Motion Picture and Electron Microscope Studies on the Embryonic Avian Osteoclast . . . . . . . . . . . . . . . 651 Allen Wachtel and Robert Mathewson and Harry Grundfest Electron Microscopic and Histochemical Comparison of the Two Types of Electroplaques of Narcine Brasiliensis 663 Russell Ross and Earl P. Benditt Wound Healing and Collagen Formation . . 677 Alan F. Bird The Ultrastructure and Histochemistry of a Nematode-Induced Giant Cell . . . . . 701 G. Adolph Ackerman Histochemistry of the Centrioles and Centrosomes of the Leukemic Cells from Human Myeloblastic Leukemia . . . . . . 717 J. V. Frei and H. Sheldon A Small Granular Component of the Cytoplasm of Keratinizing Epithelia . . 719 J. V. Frei and H. Sheldon Corpus Intra Cristam: a Dense Body Within Mitochondria of Cells in Hyperplastic Mouse Epidermis . . . . . . 724 Morris J. Karnovsky Simple methods for ``staining with lead'' at high pH in electron microscopy 729 A. Peters A Radial Component of Central Myelin Sheaths . . . . . . . . . . . . . . . . 733 Giuseppe Millonig A Modified Procedure for Lead Staining of Thin Sections . . . . . . . . . . . . 736
Richard M. Franklin A Cytochemical Description of the Multiplication of Mengovirus in L-929 Cells . . . . . . . . . . . . . . . . . 1 J. Chauveau and Y. Moulé and C. Rouiller and J. Schneebeli Isolation of Smooth Vesicles and Free Ribosomes from Rat Liver Microsomes . . 17 I. Ohad and D. Danon and S. Hestrin Synthesis of Cellulose by Acetobacter Xylinum . . . . . . . . . . . . . . . . 31 R. E. Kane The mitotic apparatus: isolation by controlled pH . . . . . . . . . . . . . 47 L. E. Roth and E. W. Daniels Electron Microscopic Studies of Mitosis in Amebae . . . . . . . . . . . . . . . 57 R. W. Merriam Some Dynamic Aspects of the Nuclear Envelope . . . . . . . . . . . . . . . . 79 F. O. Simpson and S. J. Oertelis The Fine Structure of Sheep Myocardial Cells; Sarcolemmal Invaginations and the Transverse Tubular System . . . . . . . 91 Allen C. Enders Observations on the Fine Structure of Lutein Cells . . . . . . . . . . . . . . 101 I. Elizabeth Young and Philip C. Fitz-James Chemical and Morphological Studies of Bacterial Spore Formation . . . . . . . 115 Vladimir P. Gilëv A Study of Myofibril Sarcomere Structure During Contraction . . . . . . . . . . . 135 T. M. Rizki and Rose M. Rizki Cytodifferentiation in the Rosy Mutant of \bionameDrosophila Melanogaster . . . 149 Carl M. Feldherr The Intracellular Distribution of Ferritin Following Microinjection . . . 159 George T. Rudkin and Helen A. Griech On the Persistence of Oocyte Nuclei from Fetus to Maturity in the Laboratory Mouse . . . . . . . . . . . . . . . . . 169 P. Emmelot and I. J. Mizrahi and R. Naccarato and E. L. Benedetti Changes in Function and Structure of the Endoplasmic Reticulum of Rat Liver Cells After Administration of Cysteine . . . . 177 Peter Satir On the Evolutionary Stability of the 9 + 2 Pattern . . . . . . . . . . . . . . . 181 Robert D. Allen and Ronald R. Cowden Syneresis in Ameboid Movement: Its Localization by Interference Microscopy and Its Significance . . . . . . . . . . 185 Elson L. Craig and Walter J. Frajola and Marie H. Greider An Embedding Technique for Electron Microscopy Using Epon 812 . . . . . . . 190 Julie Micou and Carter C. Collins and T. Timothy Crocker Nuclear-Cytoplasmic Relationships in Human Cells in Tissue Culture . . . . . 195 Thomas P. Ashford and Keith R. Porter Cytoplasmic Components in Hepatic Cell Lysosomes . . . . . . . . . . . . . . . 198
V. Luzzati and F. Husson The Structure of the Liquid-Crystalline Phases of Lipid-Water Systems . . . . . 207 Walther Stoeckenius Some Electron Microscopical Observations on Liquid-Crystalline Phases in Lipid-Water Systems . . . . . . . . . . 221 W. Straus Colorimetric Investigation of the Uptake of an Intravenously Injected Protein (Horseradish Peroxidase) by Rat Kidney and Effects of Competition by Egg White 231 Russell J. Barrnett The Fine Structural Localization of Acetylcholinesterase at the Myoneural Junction . . . . . . . . . . . . . . . . 247 Herbert J. Eichel and Jay S. Roth Intracellular Localization of Enzymes in Spleen . . . . . . . . . . . . . . . . . 263 Lawrence Herman and Patrick J. Fitzgerald The Degenerative Changes in Pancreatic Acinar Cells Caused by Dl-Ethionine . . 277 Lawrence Herman and Patrick J. Fitzgerald Restitution of Pancreatic Acinar Cells Following Ethionine . . . . . . . . . . 297 Bernard Weisblum and Lawrence Herman and Patrick J. Fitzgerald Changes in Pancreatic Acinar Cells During Protein Deprivation . . . . . . . 313 Jack Rosenbluth The Fine Structure of Acoustic Ganglia in the Rat . . . . . . . . . . . . . . . 329 Henry deF. Webster Transient, Focal Accumulation of Axonal Mitochondria During the Early Stages of Wallerian Degeneration . . . . . . . . . 361 Sanford L. Palay and S. M. McGee-Russell and Spencer Gordon and Mary A. Grillo Fixation of Neural Tissues for Electron Microscopy by Perfusion with Solutions of Osmium Tetroxide . . . . . . . . . . 385 Jerome S. Kaye Acrosome Formation in the House Cricket 411 W. Thoenes Fine Structure of Lipid Granules in Proximal Tubule Cells of Mouse Kidney 433 John M. Easton and Burton Goldberg and Howard Green Demonstration of Surface Antigens and Pinocytosis in Mammalian Cells with Ferritin-Antibody Conjugates . . . . . . 437 A. R. Muir and A. Peters Quintuple-Layered Membrane Junctions at Terminal Bars Between Endothelial Cells 443 Mary Bartlett Bunge and Richard P. Bunge and George D. Pappas Electron Microscopic Demonstration of Connections Between Glia and Myelin Sheaths in the Developing Mammalian Central Nervous System . . . . . . . . . 448
Gordon I. Kaye and George D. Pappas Studies on the Cornea . . . . . . . . . 457 Gordon I. Kaye and George D. Pappas and Anthony Donn and Nancy Mallett Studies on the Cornea . . . . . . . . . 481 Satish Chandra The Reversal of Mitochondrial Membrane 503 Alfred M. Elliott and John R. Kennedy and Il Jin Bak Macronuclear Events in Synchronously Dividing \bionameTetrahymena Pyriformis 515 Russell Ross and Earl P. Benditt Wound Healing and Collagen Formation . . 533 G. Benjamin Bouck Chromatophore Development, Pits, and Other Fine Structure in the Red Alga, Lomentaria Baileyana (Harv.) Farlow . . 553 J. P. Revel The Sarcoplasmic Reticulum of the Bat Cricothyroid Muscle . . . . . . . . . . 571 M. A. Epstein Observations on the Mode of Release of Herpes Virus from Infected HeLa Cells 589 H. Sheldon and F. B. Kimball Studies on Cartilage . . . . . . . . . . 599 Frank N. Low and Max R. Clevenger Polyester-Methacrylate Embedments for Electron Microscopy . . . . . . . . . . 615 Arnold L. Brown Microvilli of the Human Jejunal Epithelial Cell . . . . . . . . . . . . 623 W. S. Morgan and P. Perlmann and T. Hultin Characterization of the Pattern of Amino Acid Incorporation in Cell-Free Liver Systems by Autoradiography of Precipitin Reactions . . . . . . . . . . . . . . . 628 Renato Baserga A Study of Nucleic Acid Synthesis in Ascites Tumor Cells by Two-Emulsion Autoradiography . . . . . . . . . . . . 633 Richard G. Kessel Fine Structure of Pigment Inclusions in the Test Cells of the Ovary of Styela 637 Carl M. Feldherr and J. M. Marshall The Use of Colloidal Gold for Studies of Intracellular Exchanges in the Ameba Chaos Chaos . . . . . . . . . . . . . . 640 Richard M. Eakin and Jane A. Westfall Fine Structure of the Notochord of Amphioxus . . . . . . . . . . . . . . . 646 Emma Shelton Prolonged Survival of Rabbit Thoracic Duct Lymphocytes in a Diffusion Chamber 652
B. K. Filshie and G. E. Rogers An Electron Microscope Study of the Fine Structure of Feather Keratin . . . . . . 1 Lionel Jaffe and Helmut Etzold Orientation and Locus of Tropic Photoreceptor Molecules in Spores of Botrytis and Osmunda . . . . . . . . . . 13 John Aronson The Elongation of Myofibrils from the Indirect Flight Muscle of \bionameDrosophila . . . . . . . . . . . 33 Thomas Richardson and A. L. Tappel Swelling of Fish Mitochondria . . . . . 43 Marilyn G. Farquhar and George E. Palade Functional Evidence for the Existence of a Third Cell Type in the Renal Glomerulus . . . . . . . . . . . . . . . 55 T. Elliot Weier and William W. Thomson The Grana of Starch-Free Chloroplasts of Nicotiana Rustica . . . . . . . . . . . 89 Robert C. Buck and James M. Tisdale The Fine Structure of the Mid-Body of the Rat Erythroblast . . . . . . . . . . 109 Robert C. Buck and James M. Tisdale An Electron Microscopic Study of the Development of the Cleavage Furrow in Mammalian Cells . . . . . . . . . . . . 117 G. Adolph Ackerman Electron Microscopy of the Bursa of Fabricius of the Embryonic Chick with Particular Reference to the Lympho-Epithelial Nodules . . . . . . . 127 Hans Gunther Heide Electron Microscopic Observation of Specimens Under Controlled Gas Pressure 147 George G. Rose An Unusual Behavior of Strain HeLa Cells in Tissue Culture . . . . . . . . . . . 153 H. W. Beams and Richard Kessel Intracisternal Granules of the Endoplasmic Reticulum in the Crayfish Oöcyte . . . . . . . . . . . . . . . . . 158 Michael L. Watson Observations on a Granule Associated with Chromatin in the Nuclei of Cells of Rat and Mouse . . . . . . . . . . . . . 162 H. Moe and O. Behnke Cytoplasmic Bodies Containing Mitochondria, Ribosomes, and Rough Surfaced Endoplasmic Membranes in the Epithelium of the Small Intestine of Newborn Rats . . . . . . . . . . . . . . 168 D. M. Prescott and F. J. Bollum and B. C. Kluss Is DNA Polymerase a Cytoplasmic Enzyme? 172 D. M. Prescott and R. F. Kimball and R. F. Carrier Comparison Between the Timing of Micronuclear and Macronuclear DNA Synthesis in Euplotes Eurystomus . . . . 175 Lee D. Peachey and Andrew F. Huxley Structural Identification of Twitch and Slow Striated Muscle Fibers of the Frog 177
Michael Galton DNA Content of Placental Nuclei . . . . 183 Barbara B. McDonald Synthesis of Deoxyribonucleic Acid by Micro- and Macronuclei of \bionameTetrahymena Pyriformis . . . . . 193 William O. Rieke The in Vivo Reutilization of Lymphocytic and Sarcoma DNA by Cells Growing in the Peritoneal Cavity . . . . . . . . . . . 205 Philip Siekevitz and George E. Palade Cytochemical Study on the Pancreas of the Guinea Pig . . . . . . . . . . . . . 217 Holger Hydén and Paul W. Lange A Kinetic Study of the Neuron-Glia Relationship . . . . . . . . . . . . . . 233 Sally B. Fand and Bo Thorell Spectrophotometry of the Periodic Acid-Schiff Reaction with Pituitary Hormones in Vitro and in Histological Sections . . . . . . . . . . . . . . . . 239 A. S. Brill and J. S. Olin and B. M. Siegel The Specific Volume of Dry Protein . . . 249 Y. E. Rahman Electron Microscopy of Lysosome-Rich Fractions from Rat Thymus Isolated by Density-Gradient Centrifugation Before and After Whole-Body X-Irradiation . . . 253 Antoni Horst and Tadeusz Rudnicki The Effect of a Medium Dose (430 Roentgens) of X-Ray Irradiation on Resting Cells of the Liver . . . . . . . 261 William Bloom and Robert J. Leider Optical and Electron Microscopic Changes in Ultraviolet-Irradiated Chromosome Segments . . . . . . . . . . . . . . . . 269 Samuel Dales An Electron Microscope Study of the Early Association Between Two Mammalian Viruses and Their Hosts . . . . . . . . 303 G. G. Knappeis and F. Carlsen The Ultrastructure of the Z Disc in Skeletal Muscle . . . . . . . . . . . . 323 Åke Flock and Jan Wersäll Synaptic Structures in the Lateral Line Canal Organ of the Teleost Fish Lota Vulgaris . . . . . . . . . . . . . . . . 337 Anthony W. Linnane and Eberhards Vitols and Patricia G. Nowland Studies on the Origin of Yeast Mitochondria . . . . . . . . . . . . . . 345 W. C. Hymer and W. H. McShan Isolation of Cytoplasmic Pituitary Granules by Column Chromatography . . . 350
Dominic D. Dziewiatkowski Intracellular Synthesis of Chondroitin Sulfate . . . . . . . . . . . . . . . . 359 J. E. Amoore Oxygen Tension and the Rates of Mitosis and Interphase in Roots . . . . . . . . 365 J. E. Amoore Participation of a Non-Respiratory Ferrous Complex During Mitosis in Roots 373 Hans Ris and Walter Plaut Ultrastructure of DNA-Containing Areas in the Chloroplast of Chlamydomonas . . 383 Frank V. Mercer and Lawrence Bogorad and Rosemary Mullens Studies with Cyanidium Caldarium . . . . 393 Jack Rosenbluth Subsurface Cisterns and Their Relationship to the Neuronal Plasma Membrane . . . . . . . . . . . . . . . . 405 L. J. Rode and C. Willard Lewis and J. W. Foster Electron Microscopy of Spores of Bacillus Megaterium with Special Reference to the Effects of Fixation and Thin Sectioning . . . . . . . . . . . . 423 James A. Freeman and Ben O. Spurlock A New Epoxy Embedment for Electron Microscopy . . . . . . . . . . . . . . . 437 Robert Hadek and Hewson Swift Nuclear Extrusion and Intracisternal Inclusions in the Rabbit Blastocyst . . 445 J. M. de Beyer and J. C. H. de Man and J-P. Persijn Atpase activity on the intercalated disc and C$_z$ bands of mouse heart muscle 452 Ennio Pannese Detection of Neurofilaments in the Perikaryon of Hypertrophic Nerve Cells 457 B. C. Kluss Electron Microscopy of the Macronucleus of Euplotes Eurystomus . . . . . . . . . 462 Heinz Herrmann and Patricia L. Lebeau ATP Level, Cell Injury, and Apparent Epithelium-Stroma Interaction in the Cornea . . . . . . . . . . . . . . . . . 465 H. Sheldon and M. Silverberg and I. Kerner On the Differing Appearance of Intranuclear and Cytoplasmic Glycogen in Liver Cells in Glycogen Storage Disease 468
Valerio Monesi Autoradiographic Study of DNA Synthesis and the Cell Cycle in Spermatogonia and Spermatocytes of Mouse Testis Using Tritiated Thymidine . . . . . . . . . . 1 Leonard L. Ross and Murray B. Bornstein and Gerard M. Lehrer Electron Microscopic Observations of Rat and Mouse Cerebellum in Tissue Culture 19 Donald F. Parsons An Electron Microscope Study of Radiation Damage in the Mouse Oocyte . . 31 Jòrgen Falck Larsen Electron Microscopy of the Uterine Epithelium in the Rabbit . . . . . . . . 49 Carl M. Feldherr The Nuclear Annuli As Pathways for Nucleocytoplasmic Exchanges . . . . . . 65 John E. Dowling and Richard L. Sidman Inherited Retinal Dystrophy in the Rat 73 D. F. Ohye and W. G. Murrell Formation and Structure of the Spore of Bacillus Coagulans . . . . . . . . . . . 111 P. F. Millington and J. B. Finean Electron Microscope Studies of the Structure of the Microvilli on Principal Epithelial Cells of Rat Jejunum After Treatment in Hypo- and Hypertonic Saline 125 Kiyohide Kojima and Sadao Kozuka Structural Changes in HeLa Cells Cultivated in Serum-Free Medium . . . . 141 Jane Baxandall and P. Perlmann and B. A. Afzelius A Two-Layer Technique for Detecting Surface Antigens in the Sea Urchin Egg with Ferritin-Conjugated Antibody . . . 144 Albert W. Sedar Electron Microscopy of the Oxyntic Cell in the Gastric Glands of the Bullfrog, Rana Catesbiana . . . . . . . . . . . . 152
M. S. Buttrose The Influence of Environment on the Shell Structure of Starch Granules . . . 159 Yael Eilam and S. Klein The Effect of Light Intensity and Sucrose Feeding on the Fine Structure in Chloroplasts and on the Chlorophyll Content of Etiolated Leaves . . . . . . 169 Joon H. Rho and Margaret I. Chipchase Incorporation of Tritiated Cytidine into Ribonucleic Acid by Isolated Pea Nuclei 183 Toshio Nagano Observations on the Fine Structure of the Developing Spermatid in the Domestic Chicken . . . . . . . . . . . . . . . . 193 Peter Barland and Alex B. Novikoff and David Hamerman Electron Microscopy of the Human Synovial Membrane . . . . . . . . . . . 207 Harold F. Parks Unusual Formations of Ergastoplasm in Parotid Acinous Cells of Mice . . . . . 221 Joseph A. Grasso and Hewson Swift and G. Adolph Ackerman Observations on the Development of Erythrocytes in Mammalian Fetal Liver 235 H. Ryser and J. B. Caulfield and J. C. Aub Studies on Protein Uptake by Isolated Tumor Cells . . . . . . . . . . . . . . 255 Cosmo G. MacKenzie and Julia B. MacKenzie and Oscar K. Reiss Isolation and Properties of a Cell from Liver Characterized by Lipid-Rich Particles . . . . . . . . . . . . . . . 269 Samuel Dales and Richard M. Franklin A Comparison of the Changes in Fine Structure of L Cells During Single Cycles of Viral Multiplication, Following Their Infection with the Viruses of Mengo and Encephalomyocarditis . . . . . . . . . . 281 Robert T. Ward The Origin of Protein and Fatty Yolk in Rana Pipiens . . . . . . . . . . . . . . 303 Robert T. Ward The Origin of Protein and Fatty Yolk in Rana Pipiens . . . . . . . . . . . . . . 309 T. R. Shanthaveerappa and G. H. Bourne A Perineural Epithelium . . . . . . . . 343 G. R. Shepherd and P. C. Sanders The Complementary Effects of $2$-Mercaptoethanol and Trypsin in the Lysis of HeLa Cells . . . . . . . . . . 346
Richard W. Young Cell Proliferation and Specialization During Endochondral Osteogenesis in Young Rats . . . . . . . . . . . . . . . 357 Jan-Erik Edström and Wolfgang Beermann The Base Composition of Nucleic Acids in Chromosomes, Puffs, Nucleoli, and Cytoplasm of Chironomus Salivary Gland Cells . . . . . . . . . . . . . . . . . 371 A. Lima-de-Faria and Kirstine Borum The Period of DNA Synthesis Prior to Meiosis in the Mouse . . . . . . . . . . 381 Setsuro Ebashi and Fritz Lipmann Adenosine Triphosphate-Linked Concentration of Calcium Ions in a Particulate Fraction of Rabbit Muscle 389 I. K. Buckley Cellular Injury in Vitro: Phase Contrast Studies on Injured Cytoplasm . . . . . . 401 G. Yasuzumi Electron Microscopy and X-Ray Scanning Microanalysis of Needle Biopsy Material from Human Liver . . . . . . . . . . . . 421 Sarah P. Gibbs Nuclear Envelope-Chloroplast Relationships in Algae . . . . . . . . . 433 Howard G. Davies and Michael Spencer The Variation in the Structure of Erythrocyte Nuclei with Fixation . . . . 445 John E. Dowling and I. R. Gibbons The Fine Structure of the Pigment Epithelium in the Albino Rat . . . . . . 459 Patricia Harris Some Structural and Functional Aspects of the Mitotic Apparatus in Sea Urchin Embryos . . . . . . . . . . . . . . . . 475 Timothy H. Goldsmith Fine Structure of the Retinulae in the Compound Eye of the Honey-Bee . . . . . 489 G. Yasuzumi X-Ray Scanning Microanalysis of Elemental Iron Localized in Testicular Nutritive Cells of Cipangopaludina Malleata Reeve . . . . . . . . . . . . . 495 Michael Beer and Peter J. Highton A Simple Preparation of Graphite-Coated Grids for High Resolution Electron Microscopy . . . . . . . . . . . . . . . 499
M. N. Berry Metabolic Properties of Cells Isolated from Adult Mouse Liver . . . . . . . . . 1 M. N. Berry and F. O. Simpson Fine Structure of Cells Isolated from Adult Mouse Liver . . . . . . . . . . . 9 Åke Flock and Jan Wersäll A Study of the Orientation of the Sensory Hairs of the Receptor Cells in the Lateral Line Organ of Fish, with Special Reference to the Function of the Receptors . . . . . . . . . . . . . . . 19 Arnold J. Kroll and Toichiro Kuwabara Prevention of Phosphate-Induced Mitochondrial Swelling . . . . . . . . . 29 Holger Hydén and Endre Egyházi Changes in the Base Composition of Nuclear Ribonucleic Acid of Neurons During a Short Period of Enhanced Protein Production . . . . . . . . . . . 37 R. F. Zeigel and A. J. Dalton Speculations Based on the Morphology of the Golgi Systems in Several Types of Protein-Secreting Cells . . . . . . . . 45 Philip W. Brandt and George D. Pappas An Electron Microscopic Study of Pinocytosis in Ameba . . . . . . . . . . 55 Flaviu C. A. Romanul and Roger G. Bannister Localized Areas of High Alkaline Phosphatase Activity in the Terminal Arterial Tree . . . . . . . . . . . . . 73 Masao Sano Further Studies on the Theta Cell of the Mouse Anterior Pituitary As Revealed by Electron Microscopy, with Special Reference to the Mode of Secretion . . . 85 Russell Ross and Earl P. Benditt Wound Healing and Collagen Formation . . 99 Michael B. Sporn and Theodor Wanko and Wesley Dingman The Isolation of Cell Nuclei from Rat Brain . . . . . . . . . . . . . . . . . 109 Nirmal K. Das Synthetic Capacities of Chromosome Fragments Correlated with Their Ability to Maintain Nucleolar Material . . . . . 121 L. Stockinger Elektronenoptische Darstellung Einer Makroglobulin-Retention in Plasmazellen Des Menschlichen Knochenmarks. (German) [Electron-optical Imaging of Macroglobulin Retention in Human Bone Marrow Plasma Cells] . . . . . . . . . . 131 H. M. Selzman and Robert A. Liebelt Paneth Cell Granule of Mouse Intestine 136 Alex B. Novikoff and Edward Essner Cytolysomes and Mitochondrial Degeneration . . . . . . . . . . . . . . 140 Federico Gonzales A Masking Technique for Contrast Control in Electron Micrographs . . . . . . . . 146 Koji Uchizono The Structure of Possible Photoreceptive Elements in the Sixth Abdominal Ganglion of the Crayfish . . . . . . . . . . . . 151
J. F. Perdue and W. H. McShan Isolation and Biochemical Study of Secretory Granules from Rat Pituitary Glands . . . . . . . . . . . . . . . . . 159 Lucien G. Caro and Robert P. van Tubergen High-Resolution Autoradiography . . . . 173 Lucien G. Caro High-Resolution Autoradiogaphy . . . . . 189 A. Cecil Taylor Responses of cells to pH changes in the medium . . . . . . . . . . . . . . . . . 201 Richard L. Schultz and Phyllis W. Schultz Enzyme Distribution in the Rat Fetus and Placenta Following the Adminstration of Ethionine . . . . . . . . . . . . . . . 211 George D. Pappas and Virginia M. Tennyson An Electron Microscopic Study of the Passage of Colloidal Particles from the Blood Vessels of the Ciliary Processes and Choroid Plexus of the Rabbit . . . . 227 Gordon I. Kaye Studies on the Cornea . . . . . . . . . 241 J. R. Casley-Smith The Identification of Chylomicra and Lipoproteins in Tissue Sections and Their Passage into Jejunal Lacteals . . 259 R. E. Kane The Mitotic Apparatus . . . . . . . . . 279 Edward Essner and Alex B. Novikoff Cytological Studies on Two Functional Hepatomas . . . . . . . . . . . . . . . 289 David M. Robertson and F. Stephen Vogel Concentric Lamination of Glial Processes in Oligodendrogliomas . . . . . . . . . 313 J. V. Frei The Fine Structure of the Basement Membrane in Epidermal Tumors . . . . . . 335 Sarah P. Gibbs Chloroplast Development in Ochromonas Danica . . . . . . . . . . . . . . . . . 343 Sergei Sorokin Centrioles and the Formation of Rudimentary Cilia by Fibroblasts and Smooth Muscle Cells . . . . . . . . . . 363 F. V. Mercer and Maret Nittim and J. V. Possingham The Effect of Manganese Deficiency on the Structure of Spinach Chloroplasts 379 R. Lallier Les Effets Du Thiosorbitol Et Du ThioglycÉRol Sur La Structure De L'Appareil Mitotique De L'Oeuf De L'Oursin Paracentrotus Lividus . . . . . 382 Daniel C. Pease Demonstration of a Highly Ordered Pattern Upon a Mitochondrial Surface . . 385 Leonard Atkins and Priscilla D. Taft and Kusum P. Dalal Asynchronous DNA Synthesis of Sex Chromatin in Human Interphase Nuclei . . 390 C. Roland Leeson The Application of Diazotype Color Films to the Production of Projection Slides of Electron Microscopic Material . . . . 394 Arnold M. Seligman and Jacob S. Hanker and Arlene R. Seaman and Hannah E. Silberstein Stability of the Iodine--Carbon Bond of Radioactive Iodoalbumin in the 50 Kv Electron Beam . . . . . . . . . . . . . 395
Lois W. Tice and Russell J. Barrnett Fine Structural Localization of Adenosinetriphosphatase Activity in Heart Muscle Myofibrils . . . . . . . . 401 Arthur J. Hale Identification of Some Cytochemical Reaction Products by Historadiography 417 Arthur J. Hale Identification of Cytochemical Reaction Products by Scanning X-Ray Emission Microanalysis . . . . . . . . . . . . . 427 H. Ryser and J. C. Aub and J. B. Caulfield Studies on Protein Uptake by Isolated Tumor Cells . . . . . . . . . . . . . . 437 Alex B. Novikoff and Guy de Thé and D. Beard and J. W. Beard Electron Microscopic Study of the ATP Ase Activity of the Bai Strain a (Myeloblastosis) Avian Tumor Virus . . . 451 Arnaldo Lasansky and Flora Wald The Extracellular Space in the Toad Retina As Defined by the Distribution of Ferrocyanide . . . . . . . . . . . . . . 463 Alden V. Loud A Method for the Quantitative Estimation of Cytoplasmic Structures . . . . . . . 481 Gunter F. Bahr and Elmar Zeitler Study of Mitochondria in Rat Liver . . . 489 Ralph T. Hinegardner The Isolation of Nuclei from Eggs and Embryos of the Sea Urchin . . . . . . . 503 David N. Orth and Howard E. Morgan The Effect of Insulin, Alloxan Diabetes, and Anoxia on the Ultrastructure of the Rat Heart . . . . . . . . . . . . . . . 509 M. Rabinovitch and W. Plaut Cytoplasmic DNA Synthesis in Amoeba Proteus . . . . . . . . . . . . . . . . 525 M. Rabinovitch and W. Plaut Cytoplasmic DNA Synthesis in Amoeba Proteus . . . . . . . . . . . . . . . . 535 Lars Ernster and Philip Siekevitz and George E. Palade Enzyme-Structure Relationships in the Endoplasmic Reticulum of Rat Liver . . . 541 Lars Ernster and Lois C. Jones A Study of the Nucleoside Tri- and Diphosphate Activities of Rat Liver Microsomes . . . . . . . . . . . . . . . 563 A. C. Fabergé and C. Willard Lewis N-Vinylpyrrolidone As a Water Compatible Constituent of Embedding Resins for Sectioning in Electron Microscopy . . . 579 Hideo Yamagishi Interaction Between Nucleic Acids and Berberine Sulfate . . . . . . . . . . . 589 Dorothy Gelber Feldman A Method of Staining Thin Sections with Lead Hydroxide for Precipitate-Free Sections . . . . . . . . . . . . . . . . 592 Ragnar Olsson The Relationship Between Ciliary Rootlets and Other Cell Structures . . . 596 Aharon Gibor and Sam Granick Ultraviolet Sensitive Factors in the Cytoplasm That Affect the Differentiation of Euglena Plastids . . 599 Ivar Agrell and Hans-Åke Bergqvist Cytochemical Evidence for Varied DNA Complexes in the Nuclei of Undifferentiated Cells . . . . . . . . . 604
H. Warshawsky and C. P. Leblond and B. Droz Synthesis and Migration of Proteins in the Cells of the Exocrine Pancreas As Revealed by Specific Activity Determination from Radioautographs . . . 1 Elizabeth D. Hay and J. P. Revel The Fine Structure of the DNP Component of the Nucleus . . . . . . . . . . . . . 29 Jae Kwon Choi The Fine Structure of the Urinary Bladder of the Toad, Bufo Marinus . . . 53 J. K. Koehler and K. Mühlethaler and A. Freywyssling Electron Microscopic Autoradiography . . 73 J. Lust and P. Drochmans Effect of Trypsin on Liver Microsomes 81 Steven L. Wissig The Anatomy of Secretion in the Follicular Cells of the Thyroid Gland 93 M. Mussgay and J. Weibel Electron Microscopic Studies on the Development of Vesicular Stomatitis Virus in Kb Cells . . . . . . . . . . . 119 Royall T. Moore and James H. McAlear Fine Structure of Mycota . . . . . . . . 131 Jack Rosenbluth Contrast Between Osmium-Fixed and Permanganate-Fixed Toad Spinal Ganglia 143 Toshiyuki Yamamoto Some Observations on the Fine Structure of the Sympathetic Ganglion of Bullfrog 159 Henry Rappaport and Takashi Nakai and Hewson Swift The Fine Structure of Normal and Neoplastic Melanocytes in the Syrian Hamster, with Particular Reference to Carcinogen-Induced Melanotic Tumors . . 171 J. P. Revel and D. W. Fawcett and C. W. Philpott Observations on Mitochondrial Structure 187 Willy Stäubli A New Embedding Technique for Electron Microscopy, Combining a Water-Soluble Epoxy Resin (Durcupan) with Water-Insoluble Araldite . . . . . . . . 197 P. S. Moorhead and Vittorio Defendi Asynchrony of DNA Synthesis in Chromosomes of Human Diploid Cells . . . 202
Eugene Bell and Y. T. Thathachari Development of Feather Keratin During Embryogenesis of the Chick . . . . . . . 215 N. F. Rodman and J. C. Painter and N. B. McDevitt Platelet Disintegration During Clotting 225 G. R. Martin and E. Schiffmann and H. A. Bladen and Marie Nylen Chemical and Morphological Studies on the in Vitro Calcification of Aorta . . 243 Andrew G. Plaut and William H. Fishman Beta Glucuronidase-Rich Cytoplasmic Particles in Androgen-Stimulated Mouse Kidney . . . . . . . . . . . . . . . . . 253 Yasuo Hotta and Herbert Stern Inhibition of Protein Syntheses During Meiosis and Its Bearing on Intracellular Regulation . . . . . . . . . . . . . . . 259 J. Walter Wilson and Elizabeth H. Leduc Mitochondrial Changes in the Liver of Essential Fatty Acid-Deficient Mice . . 281 Douglas A. Nelson and Ellis S. Benson On the Structural Continuities of the Transverse Tubular System of Rabbit and Human Myocardial Cells . . . . . . . . . 297 A. Lima-de-Faria and J. Reitalu Heterochromatin in Human Male Leukocytes 315 David S. Smith The Organization and Innervation of the Luminescent Organ in a Firefly, Photuris Pennsylvanica (Coleoptera) . . . . . . . 323 J. C. Thaemert The Ultrastructure and Disposition of Vesiculated Nerve Processes in Smooth Muscle . . . . . . . . . . . . . . . . . 361 Bryce L. Munger and Sanford I. Roth The Cytology of the Normal Parathyroid Glands of Man and Virginia Deer . . . . 379 Germaine Cohen-Bazire and Riyo Kunisawa The Fine Structure of Rhodospirillum Rubrum . . . . . . . . . . . . . . . . . 401 Werner R. Loewenstein and Yoshinobu Kanno The Electrical Conductance and Potential Across the Membrane of Some Cell Nuclei 421 G. Dallner and S. Orrenius and A. Bergstrand Isolation and Properties of Rough and Smooth Vesicles from Rat Liver . . . . . 426 Mary A. Grillo and Sanford L. Palay Ciliated Schwann Cells in the Autonomic Nervous System of the Adult Rat . . . . 430 Karlheinz Bier Synthese, Interzellulärer Transport, Und Abbau Von Ribonukleinsäure Im Ovar Der Stubenfliege \bionameMusca Domestica. (German) [Synthesis, Intercellular Transport, and Breakdown of Ribonucleic Acid in the Ovary of the Housefly \bionameMusca Domestica] . . . . . . . . 436
Charles G. Rosa and Kwan-Chung Tsou The Use of Tetranitro-Blue Tetrazolium for the Cytochemical Localization of Succinic Dehydrogenase . . . . . . . . . 445 Donald G. Walker and Arnold M. Seligman The Use of Formalin Fixation in the Cytochemical Demonstration of Succinic and Dpn- and Tpn-Dependent Dehydrogenases in Mitochondria . . . . . 455 Alexandra von der Decken Labeling With $^{14}$C Amino Acids of Albumin-Like Protein by Rat Liver Ribonucleoprotein Particles . . . . . . 471 David J. L. Luck Formation of Mitochondria in Neurospora Crassa . . . . . . . . . . . . . . . . . 483 John Tooze and Howard G. Davies The Occurrence and Possible Significance of Haemoglobin in the Chromosomal Regions of Mature Erythrocyte Nuclei of the Newt Triturus Cristatus Cristatus 501 T. M. Rizki Genetic Control of Cytodifferentiation 513 Anders Hamberger and Holger Hydén Inverse Enzymatic Changes in Neurons and Glia During Increased Function and Hypoxia . . . . . . . . . . . . . . . . 521 Oswald Hess and Günther F. Meyer Chromosomal Differentiations of the Lampbrush Type Formed by the Y Chromosome in \bionameDrosophila Hydei and \bionameDrosophila Neohydei . . . . 527 Susumu Ito and Robert J. Winchester The Fine Structure of the Gastric Mucosa in the Bat . . . . . . . . . . . . . . . 541 A. D. Warth and D. F. Ohye and W. G. Murrell The Composition and Structure of Bacterial Spores . . . . . . . . . . . . 579 A. D. Warth and D. F. Ohye and W. G. Murrell Location and Composition of Spore Mucopeptide in Bacillus Species . . . . 593 Donald B. Malkoff and Bernard L. Strehler The Ultrastructure of Isolated and in Situ Human Cardiac Age Pigment . . . . . 611 June D. Almeida and Allan F. Howatson A Negative Staining Method for Cell-Associated Virus . . . . . . . . . 616 Donald F. Parsons Negative Staining of Thinly Spread Cells and Associated Virus . . . . . . . . . . 620 I. R. Gibbons A Method for Obtaining Serial Sections of Known Orientation from Single Spermatozoa . . . . . . . . . . . . . . 626 E. Kallenbach and E. Sandborn and H. Warshawsky The Golgi Apparatus of the Ameloblast of the Rat at the Stage of Enamel Matrix Formation . . . . . . . . . . . . . . . 629
C. T. Ashworth and F. J. Luibel and S. C. Stewart The Fine Structural Localization of Adenosine Triphosphatase in the Small Intestine, Kidney, and Liver of the Rat 1 David D. Sabatini and Klaus Bensch and Russell J. Barrnett Cytochemistry and Electron Microscopy 19 S. T. Takats and R. M. S. Smellie Thymidine Degradation Products in Plant Tissues Labeled with Tritiated Thymidine 59 W. C. Hymer and W. H. McShan Isolation of Rat Pituitary Granules and the Study of Their Biochemical Properties and Hormonal Activities . . . 67 T. M. Rizki and Rose M. Rizki An Inducible Enzyme System in the Larval Cells of \bionameDrosophila Melanogaster 87 Peter Albersheim and Ursula Killias The Use of Bismuth As an Electron Stain for Nucleic Acids . . . . . . . . . . . 93 J. Ross Colvin The Size of the Cellulose Microfibril 105 Audrey M. Glauert and Mary R. Daniel and J. A. Lucy and J. T. Dingle Studies on the Mode of Action of Excess of Vitamin A . . . . . . . . . . . . . . 111 C. F. Robinow Observations on Cell Growth, Mitosis, and Division in the Fungus Basidiobolus Ranarum . . . . . . . . . . . . . . . . 123 J. Jacob and J. L. Sirlin Electron Microscope Studies on Salivary Gland Cells . . . . . . . . . . . . . . 153 J. G. Lafontaine and L. A. Chouinard A Correlated Light and Electron Microscope Study of the Nucleolar Material During Mitosis in \bionameVicia Faba . . . . . . . . . . . . . . . . . . 167 Ben O. Spurlock and Victoria C. Kattine and James A. Freeman Technical Modifications in Maraglas Embedding . . . . . . . . . . . . . . . 203 Edward S. Reynolds The use of lead citrate at high pH as an electron-opaque stain in electron microscopy . . . . . . . . . . . . . . . 208 Patrick Echlin The Fine Structure of the Cell Boundary of the Blue-Green Alga Anacystis Montana 212 W. Gordon Whaley and Hilton H. Mollenhauer The Golgi Apparatus and Cell Plate Formation --- a Postulate . . . . . . . 216 Hilton H. Mollenhauer and W. Gordon Whaley An Observation on the Functioning of the Golgi Apparatus . . . . . . . . . . . . 222
Richard F. Fisher and David J. Holbrook and J. Logan Irvin Density Gradient Isolation of Rat Liver Nuclei with High DNA Content . . . . . . 231 Robert Love and Peter Wildy Cytochemical Studies of the Nucleoproteins of HeLa Cells Infected with Herpes Virus . . . . . . . . . . . 237 Donald G. Walker A Survey of Dehydrogenases in Various Epithelial Cells in the Rat . . . . . . 255 Dante G. Scarpelli and Elson L. Craig The Fine Localization of Nucleoside Triphosphatase Activity in the Retina of the Frog . . . . . . . . . . . . . . . . 279 Murray D. Rosenberg The Relative Extensibility of Cell Surfaces . . . . . . . . . . . . . . . . 289 George J. Todaro and Howard Green Quantitative Studies of the Growth of Mouse Embryo Cells in Culture and Their Development into Established Lines . . . 299 David Epel The Effects of Carbon Monoxide Inhibition on ATP Level and the Rate of Mitosis in the Sea Urchin Egg . . . . . 315 I. Ohad and D. Danon and S. Hestrin The Use of Shadow-Casting Technique for Measurement of the Width of Elongated Particles . . . . . . . . . . . . . . . 321 Claudio Pellegrino and Clara Franzini An Electron Microscope Study of Denervation Atrophy in Red and White Skeletal Muscle Fibers . . . . . . . . . 327 S. Ahmad Shafiq Electron Microscopic Studies on the Indirect Flight Muscles of \bionameDrosophila Melanogaster . . . . 351 S. Ahmad Shafiq Electron Microscopic Studies on the Indirect Flight Muscles of \bionameDrosophila melanogaster . . . . 363 Marilyn G. Farquhar and George E. Palade Junctional Complexes in Various Epithelia . . . . . . . . . . . . . . . 375 Toshiyuki Yamamoto On the Thickness of the Unit Membrane 413 Nicole Granboulan and P. Tournier and R. Wicker and W. Bernhard An Electron Microscope Study of the Development of Sv40 Virus . . . . . . . 423 Walther Stoeckenius Some Observations on Negatively Stained Mitochondria . . . . . . . . . . . . . . 443 J. Rosenbluth Fine Structure of Epineurial Muscle Cells in \bionameAplysia Californica . . 455
Arthur M. Dannenberg and Marvin S. Burstone and Paul C. Walter and June W. Kinsley A Histochemical Study of Phagocytic and Enzymatic Functions of Rabbit Mononuclear and Polymorphonuclear Exudate Cells and Alveolar Macrophages 465 Rachel Oren and Ann E. Farnham and Kazuhisa Saito and Eva Milofsky and Manfred L. Karnovsky Metabolic Patterns in Three Types of Phagocytizing Cells . . . . . . . . . . 487 Väinö K. Hopsu and George G. Glenner A Histochemical Enzyme Kinetic System Applied to the Trypsin-Like Amidase and Esterase Activity in Human Mast Cells 503 Eleanor R. Siperstein Identification of the Adrenocorticotrophin-Producing Cells in the Rat Hypophysis by Autoradiography 521 V. T. Marchesi and R. J. Barrnett The Demonstration of Enzymatic Activity in Pinocytic Vesicles of Blood Capillaries with the Electron Microscope 547 Ann B. Jacobson and Hewson Swift and Lawrence Bogorad Cytochemical Studies Concerning the Occurrence and Distribution of RNA in Plastids of \bionameZea Mays . . . . . . 557 Bertalan Csillik Submicroscopic Organization of the Postsynaptic Membrane in the Myoneural Junction . . . . . . . . . . . . . . . . 571 Francesco Clementi and Gian Paolo Zocche Morphological and Pharmacological Effects of Reserpine, Given Alone Or After Iproniazid, on the Catechol Amines of the Adrenal Glands of the Rat . . . . 587 Elliott W. Strauss The Absorption of Fat by Intestine of Golden Hamster in Vitro . . . . . . . . 597 H. Moor and K. Mühlethaler Fine Structure in Frozen-Etched Yeast Cells . . . . . . . . . . . . . . . . . 609 Wolf H. Fahrenbach The Sarcoplasmic Reticulum of Striated Muscle of a Cyclopoid Copepod . . . . . 629 John Mcd. Tormey Fine Structure of the Ciliary Epithelium of the Rabbit, with Particular Reference to ``Infolded Membranes,'' ``Vesicles,'' and the Effects of Diamox . . . . . . . 641 Jane Overton Intercellular Connections in the Outgrowing Stolon of Cordylophora . . . 661 J. Sri Ram and Saroj S. Tawde and G. B. Pierce and A. R. Midgley Preparation of Antibody-Ferritin Conjugates for Immuno-Electron Microscopy . . . . . . . . . . . . . . . 673 William R. Hendee and William Zebrun and Frederick J. Bonte Anomalous Structures in the Cytoplasm of HeLa Cells Cultured in the Presence of $5$-Bromodeoxyuridine . . . . . . . . . 675
Joseph Post and Cheng-Ya Huang and Joseph Hoffman The Replication Time and Pattern of the Liver Cell in the Growing Rat . . . . . 1 Frank K. Thorp and Albert Dorfman The Occurrence of Intracellular Chondroitin Sulfate . . . . . . . . . . 13 Robert D. Campo and Dominic D. Dziewiatkowski Turnover of the Organic Matrix of Cartilage and Bone As Visualized by Autoradiography . . . . . . . . . . . . 19 Ivan L. Cameron and Richard C. Greulich Evidence for an Essentially Constant Duration of DNA Synthesis in Renewing Epithelia of the Adult Mouse . . . . . . 31 Max L. Birnstiel and Beal B. Hyde Protein Synthesis by Isolated Pea Nucleoli . . . . . . . . . . . . . . . . 41 Samuel Dales The Uptake and Development of Vaccinia Virus in Strain L Cells Followed with Labeled Viral Deoxyribonucleic Acid . . 51 G. A. Meek and S. Bradbury Localization of Thiamine Pyrophosphatase Activity in the Golgi Apparatus of a Mollusc, \bionameHelix Aspersa . . . . . 73 Helen A. Padykula and Geraldine F. Gauthier Cytochemical Studies of Adenosine Triphosphatases in Skeletal Muscle Fibers . . . . . . . . . . . . . . . . . 87 M. U. Nylen and E. D. Eanes and K.-Å. Omnell Crystal Growth in Rat Enamel . . . . . . 109 Arnold Tamarin and Leo M. Sreebny An Analysis of Desmosome Shape, Size, and Orientation by the Use of Histometric and Densitometric Methods with Electron Microscopy . . . . . . . . 125 Shuichi Karasaki Studies on Amphibian Yolk . . . . . . . 135 Robin A. Wallace and Shuichi Karasaki Studies on Amphibian Yolk . . . . . . . 153 Robert M. Herndon The Fine Structure of the Purkinje Cell 167 Alden V. Loud and Yutaka Mishima The Induction of Melanization in Goldfish Scales with Acth, in Vitro . . 181 G. W. Richter and A. Kellner Hypertrophy of the Human Heart at the Level of Fine Structure . . . . . . . . 195 Heather Donald Mayor and Liane E. Jordan Acrolein --- a Fine Structure Fixative for Viral Cytochemistry . . . . . . . . 207 R. Price Peterson A Note on the Structure of Crayfish Myofilaments . . . . . . . . . . . . . . 213
Robert D. Allen and James Brault and Robert D. Moore A New Method of Polarization Microscopic Analysis . . . . . . . . . . . . . . . . 223 Elliott Robbins and Philip I. Marcus Dynamics of Acridine Orange-Cell Interaction . . . . . . . . . . . . . . 237 O. Behnke Demonstration of Acid Phosphatase-Containing Granules and Cytoplasmic Bodies in the Epithelium of Foetal Rat Duodenum During Certain Stages of Differentiation . . . . . . . 251 Rachele Maggio and Philip Siekevitz and George E. Palade Studies on Isolated Nuclei . . . . . . . 267 Rachele Maggio and Philip Siekevitz and George E. Palade Studies on Isolated Nuclei . . . . . . . 293 Daniel C. Pease The Ultrastructure of Flagellar Fibrils 313 Audrey M. Glauert and D. Kerridge and R. W. Horne The Fine Structure and Mode of Attachment of the Sheathed Flagellum of Vibrio Metchnikovii . . . . . . . . . . 327 Toshio Nagano Fine Structural Changes in the Flagellum of the Spermatid in Experimental Cryptorchidism of the Rat . . . . . . . 337 Peter Satir Studies on Cilia . . . . . . . . . . . . 345 David B. Slautterback Cytoplasmic Microtubules . . . . . . . . 367 C. W. Philpott and D. E. Copeland Fine Structure of Chloride Cells from Three Species of Fundulus . . . . . . . 389 A. C. Enders and R. K. Enders and S. Schlafke An Electron Microscope Study of the Gland Cells of the Mink Endometrium . . 405 R. Wilsenach Differentiation of the Chloroplast of Anthoceros . . . . . . . . . . . . . . . 419 Ryan W. Drum The Cytoplasmic Fine Structure of the Diatom, Nitzschia Palea . . . . . . . . 429 G. Benjamin Bouck Stratification and Subsequent Behavior of Plant Cell Organelles . . . . . . . . 441 Konrad Keck and Elizabeth A. Choules An Analysis of Cellular and Subcellular Systems Which Transform the Species Character of Acid Phosphatase in Acetabularia . . . . . . . . . . . . . . 459 Liselotte Mezger-Freed Evidence for Synthesis of Deoxyribonucleic Acid in Enucleated Rana Pipiens Eggs . . . . . . . . . . . . . . 471 Wolf H. Fahrenbach A Contribution to Glass Knife Breaking 475 Leonard Napolitano Cytolysomes in Metabolically Active Cells . . . . . . . . . . . . . . . . . 478
Lester Packer Size and Shape Transformations Correlated with Oxidative Phosphorylation in Mitochondria . . . . 487 Lester Packer Size and Shape Transformations Correlated with Oxidative Phosphorylation in Mitochondria . . . . 495 Henry Tedeschi and Joseph M. James and William Anthony Photometric Evidence for the Osmotic Behavior of Rat Liver Microsomes . . . . 503 B. J. Bryant Reutilization of Lymphocyte DNA by Cells of Intestinal Crypts and Regenerating Liver . . . . . . . . . . . . . . . . . 515 H. J. Evans and J. R. K. Savage The Relation Between DNA Synthesis and Chromosome Structure As Resolved by X-Ray Damage . . . . . . . . . . . . . . 525 Robert M. Kodama and Henry Tedeschi An Electron Microscope Study of Calf Thymus Nuclear Preparations Isolated in Sucrose Solutions . . . . . . . . . . . 541 J. E. Amoore Non-Identical Mechanisms of Mitotic Arrest by Respiratory Inhibitors in Pea Root Tips and Sea Urchin Eggs . . . . . 555 Morton D. Maser and Robert V. Rice Soluble Earthworm Cuticle Collagen: a Possible Dimer of Tropocollagen . . . . 569 Mary A. Bonneville Fine Structural Changes in the Intestinal Epithelium of the Bullfrog During Metamorphosis . . . . . . . . . . 579 Jerry S. Trier Studies on Small Intestinal Crypt Epithelium . . . . . . . . . . . . . . . 599 H. W. Beams and R. G. Kessel Electron Microscope Studies on Developing Crayfish Oocytes with Special Reference to the Origin of Yolk . . . . 621 Edith Krugelis MacRae Observations on the Fine Structure of Pharyngeal Muscle in the Planarian Dugesia Tigrina . . . . . . . . . . . . 651 Leonard Napolitano The Differentiation of White Adipose Cells . . . . . . . . . . . . . . . . . 663 A. D. Brown and C. D. Shorey The Cell Envelopes of Two Extremely Halophilic Bacteria . . . . . . . . . . 681 Edward J. Reith The Ultrastructure of Ameloblasts During Early Stages of Maturation of Enamel . . 691 Sasha Malamed Use of a Microcentrifuge for Preparation of Isolated Mitochondria and Cell Suspensions for Electron Microscopy . . 696 Norimitsu Watabe Decalcification of Thin Sections for Electron Microscope Studies of Crystal-Matrix Relationships in Mollusc Shells . . . . . . . . . . . . . . . . . 701 Mary A. Bonneville and Bruce R. Voeller A New Cytoplasmic Component of Plant Cells . . . . . . . . . . . . . . . . . 703
Edwin W. Taylor Relation of Protein Synthesis to the Division Cycle in Mammalian Cell Cultures . . . . . . . . . . . . . . . . 1 Maureen Owen Cell population kinetics of an osteogenic tissue $ \bullet $ I . . . . 19 Maureen Owen and Sheila MacPherson Cell population kinetics of an osteogenic tissue $ \bullet $ II . . . . 33 Yasuo Hotta and Herbert Stern Synthesis of Messenger-Like Ribonucleic Acid and Protein During Meiosis in Isolated Cells of Trillium Erectum . . . 45 M. Chora\.zy and A. Bendich and E. Borenfreund and D. J. Hutchison Studies on the Isolation of Metaphase Chromosomes . . . . . . . . . . . . . . 59 M. Chora\.zy and A. Bendich and E. Borenfreund and O. L. Ittensohn and D. J. Hutchison Uptake of Mammalian Chromosomes by Mammalian Cells . . . . . . . . . . . . 71 Paul K. Brown and I. R. Gibbons and George Wald The Visual Cells and Visual Pigment of the Mudpuppy, Necturus . . . . . . . . . 79 John Aronson Overlap of the Birefringent Component of Adjacent a Regions During the Induced Shortening of Fibrils Teased from \bionameDrosophila Muscle . . . . . . . 107 David S. Smith The Structure of Flight Muscle Sarcosomes in the Blowfly \bionameCalliphora Erythrocephala (Diptera) . . . . . . . . . . . . . . . 115 Edward S. Reynolds Liver Parenchymal Cell Injury . . . . . 139 J. David Robertson and Thomas S. Bodenheimer and David E. Stage The Ultrastructure of Mauthner Cell Synapses and Nodes in Goldfish Brains 159 J. David Robertson The Occurrence of a Subunit Pattern in the Unit Membranes of Club Endings in Mauthner Cell Synapses in Goldfish Brains . . . . . . . . . . . . . . . . . 201 Gabriel Gasic and Leonard Berwick Hale Stain for Sialic Acid-Containing Mucins . . . . . . . . . . . . . . . . . 223 Björn A. Afzelius The Nucleus of Noctiluca Scintillans . . 229 M. C. Ledbetter and K. R. Porter A ``Microtubule'' in Plant Cell Fine Structure . . . . . . . . . . . . . . . 239 Thomas L. Hayes and Frank T. Lindgren and John W. Gofman A Quantitative Determination of the Osmium Tetroxide-Lipoprotein Interaction 251 Morris J. Karnovsky and Katharina Hug The Nature of the M Band Enzyme in Rat Ventricular Muscle . . . . . . . . . . . 255 Paul R. Gross and Gilles H. Cousineau Synthesis of Spindle-Associated Proteins in Early Cleavage . . . . . . . . . . . 260
Carol G. Konrad Protein Synthesis and RNA Synthesis During Mitosis in Animal Cells . . . . . 267 J.-E. Edström and J. G. Gall The Base Composition of Ribonucleic Acid in Lampbrush Chromosomes, Nucleoli, Nuclear Sap, and Cytoplasm of \bionameTriturus Oocytes . . . . . . . . 279 M. R. Loran and T. T. Crocker Population Dynamics of Intestinal Epithelia in the Rat Two Months After Partial Resection of the Ileum . . . . . 285 W. L. Stahl and J. C. Smith and L. M. Napolitano and R. E. Basford Brain Mitochondria . . . . . . . . . . . 293 Diana S. Beattie and Howard R. Sloan and R. E. Basford Brain Mitochondria . . . . . . . . . . . 309 Arnold W. Lindall and G. Eric Bauer and Padmaker K. Dixit and Arnold Lazarow Isolation of an Insulin Secretion Granule Fraction . . . . . . . . . . . . 317 M. A. Epstein and S. J. Holt The Localization by Electron Microscopy of HeLa Cell Surface Enzymes Splitting Adenosine Triphosphate . . . . . . . . . 325 M. A. Epstein and S. J. Holt Electron Microscope Observations on the Surface Adenosine Triphosphatase-Like Enzymes of HeLa Cells Infected with Herpes Virus . . . . . . . . . . . . . . 337 Miro Brzin and \vZiva Majcen-Tka\vcev Cholinesterase in Denervated End Plates and Muscle Fibres . . . . . . . . . . . 349 John Aronson Observations on the Variations in Size of the a Region of Arthropod Muscle . . 359 Sally G. Page and H. E. Huxley Filament Lengths in Striated Muscle . . 369 Richard G. Kessel Electron Microscope Studies on the Origin of Annulate Lamellae in Oocytes of Necturus . . . . . . . . . . . . . . 391 M. W. Brightman and S. L. Palay The Fine Structure of Ependyma in the Brain of the Rat . . . . . . . . . . . . 415 D. R. Inman and E. H. Cooper Electron Microscopy of Human Lymphocytes Stimulated by Phytohaemagglutinin . . . 441 Elisabeth Gantt and Howard J. Arnott Chloroplast Division in the Gametophyte of the Fern Matteuccia Struthiopteris (L.) Todaro . . . . . . . . . . . . . . 446 J. A. Dickson and I. Leslie The Reaggregation and Metabolism of Dissociated Adult Guinea Pig Cells in Filter-Well Cultures . . . . . . . . . . 449
Thomas J. Byers and Dorothy B. Platt and Lester Goldstein The Cytonucleoproteins of Amebae . . . . 453 Thomas J. Byers and Dorothy B. Platt and Lester Goldstein The Cytonucleoproteins of Amebae . . . . 467 Arthur L. Colwin and Laura Hunter Colwin Role of the Gamete Membranes in Fertilization in Saccoglossus Kowalevskii (Enteropneusta) . . . . . . 477 Laura Hunter Colwin and Arthur L. Colwin Role of the Gamete Membranes in Fertilization in Saccoglossus Kowalevskii (Enteropneusta) . . . . . . 501 D. Stegwee and E. C. Kimmel and J. A. de Boer and S. Henstra Hormonal Control of Reversible Degeneration of Flight Muscle in the Colorado Potato Beetle, Leptinotarsa Decemlineata Say (Coleoptera) . . . . . 519 Neil C. R. Merrillees and Geoffrey Burnstock and Mollie E. Holman Correlation of Fine Structure and Physiology of the Innervation of Smooth Muscle in the Guinea Pig \bionameVas Deferens . . . . . . . . . . . . . . . . 529 William T. Hall and George Claus Ultrastructural Studies on the Blue-Green Algal Symbiont in Cyanophora Paradoxa Korschikoff . . . . . . . . . . 551 Seiichi Matsumoto Electron Microscope Studies of Rabies Virus in Mouse Brain . . . . . . . . . . 565 Margit M. K. Nass and Sylvan Nass Intramitochondrial Fibers with DNA Characteristics . . . . . . . . . . . . 593 Sylvan Nass and Margit M. K. Nass Intramitochondrial Fibers with DNA Characteristics . . . . . . . . . . . . 613 Norma J. Lang An Additional Ultrastructural Component of Flagella . . . . . . . . . . . . . . 631 Walter J. Humphreys Preparation of Carbon Films by Use of a Glycerin Substrate . . . . . . . . . . . 634 Clara Franzini-Armstrong Pores in the Sarcoplasmic Reticulum . . 637 D. C. Swartzendruber and C. C. Congdon Electron Microscope Observations on Tingible Body Macrophages in Mouse Spleen . . . . . . . . . . . . . . . . . 641 Luis R. Otero-Vilardebó and Nathan Lane and Gabriel C. Godman Demonstration of Mitochondrial ATP Ase Activity in Formalin-Fixed Colonic Epithelial Cells . . . . . . . . . . . . 647
Ray M. Iverson The Content and Relative Base Ratios of Ribonucleic Acid in Amoeba . . . . . . . 1 Reinhard L. Friede The Enzymatic Response of Astrocytes to Various Ions in Vitro . . . . . . . . . 5 John Seed The Relations Between DNA, RNA, and Protein in Normal Embryonic Cell Nuclei and Spontaneous Tumour Cell Nuclei . . . 17 Coral Duck-Chong and J. K. Pollak and R. J. North The Relation Between the Intracellular Ribonucleic Acid Distribution and Amino Acid Incorporation in the Liver of the Developing Chick Embryo . . . . . . . . 25 James German The Pattern of DNA Synthesis in the Chromosomes of Human Blood Cells . . . . 37 Joseph R. Williamson Adipose Tissue . . . . . . . . . . . . . 57 E. W. Daniels and L. E. Roth Electron Microscopy of Mitosis in a Radiosensitive Giant Amoeba . . . . . . 75 Paul F. Parakkal and A. Gedeon Matoltsy A Study of the Fine Structure of the Epidermis of Rana Pipiens . . . . . . . 85 Lee D. Peachey Electron Microscopic Observations on the Accumulation of Divalent Cations in Intramitochondrial Granules . . . . . . 95 Alfred M. Elliott and Il Jin Bak The Fate of Mitochondria During Aging in \bionameTetrahymena Pyriformis . . . . . 113 Everett Anderson Oocyte Differentiation and Vitellogenesis in the Roach \bionamePeriplaneta Americana . . . . . 131 W. S. Tyler and J. Pangborn Laminated Membrane Surface and Osmiophilic Inclusions in Avian Lung Epithelium . . . . . . . . . . . . . . . 157 B. Boothroyd The Problem of Demineralisation in Thin Sections of Fully Calcified Bone . . . . 165 G. G. Selman and A. Jurand An Electron Microscope Study of the Endoplasmic Reticulum in Newt Notochord Cells After Disturbance with Ultrasonic Treatment and Subsequent Regeneration 175 I. L. Cameron Is the Duration of DNA Synthesis in Somatic Cells of Mammals and Birds a Constant? . . . . . . . . . . . . . . . 185 Carl M. Feldherr Binding Within the Nuclear Annuli and Its Possible Effect on Nucleocytoplasmic Exchanges . . . . . . . . . . . . . . . 188 M. Steinert Le Chondriome De Trypanosoma Mega . . . 192
A. S. G. Curtis The Mechanism of Adhesion of Cells to Glass . . . . . . . . . . . . . . . . . 199 G. W. Claus and L. E. Roth Fine Structure of the Gram-Negative Bacterium Acetobacter Suboxydans . . . . 217 Peter R. Bell and Kurt Mühlethaler The Degeneration and Reappearance of Mitochondria in the Egg Cells of a Plant 235 L. E. Roth and Y. Shigenaka The Structure and Formation of Cilia and Filaments in Rumen Protozoa . . . . . . 249 Yoshihiro Hamashima and John G. Harter and Albert H. Coons The Localization of Albumin and Fibrinogen in Human Liver Cells . . . . 271 A. Peters Further Observations on the Structure of Myelin Sheaths in the Central Nervous System . . . . . . . . . . . . . . . . . 281 E. S. Boatman Observations on the Fine Structure of Spheroplasts of Rhodospirillum Rubrum 297 Thomas F. Roth and Keith R. Porter Yolk Protein Uptake in the Oocyte of the Mosquito \bionameAedes Aegypti. L . . . 313 Herbert Voelz The ``Spindle-Shaped Body'' in Fibroblasts . . . . . . . . . . . . . . 333 Robert M. Herndon Lamellar Bodies, an Unusual Arrangement of the Granular Endoplasmic Reticulum 338 Alfredo Mariano Garcia Feulgen-DNA Values in Megakaryocytes . . 342 Robert M. Thornton and Kenneth V. Thimann On a Crystal-Containing Body in Cells of the Oat Coleoptile . . . . . . . . . . . 345 William P. Callahan and Jack A. Horner The Use of Vanadium As a Stain for Electron Microscopy . . . . . . . . . . 350 Elliott Robbins and Nicholas K. Gonatas In Vitro Selection of the Mitotic Cell for Subsequent Electron Microscopy . . . 356
Woutera van Iterson and W. Leene A Cytochemical Localization of Reductive Sites in a Gram-Positive Bacterium . . . 361 Woutera van Iterson and W. Leene A Cytochemical Localization of Reductive Sites in a Gram-Negative Bacterium . . . 377 Douglas Cameron Barker and George Svihla Localization of Cytoplasmic Nucleic Acid During Growth and Encystment of Entamoeba Invadens . . . . . . . . . . . 389 Frances Kallman and Clifford Grobstein Fine Structure of Differentiating Mouse Pancreatic Exocrine Cells in Transfilter Culture . . . . . . . . . . . . . . . . 399 Norman K. Wessells DNA Synthesis, Mitosis, and Differentiation in Pancreatic Acinar Cells in Vitro . . . . . . . . . . . . . 415 D. K. Hill The Location of Adenine Nucleotide in the Striated Muscle of the Toad . . . . 435 Lawrence M. Roth and Sarah A. Luse Fine Structure of the Neurohypophysis of the Opossum (\bionameDidelphis Virginiana) . . . . . . . . . . . . . . 459 Lucien G. Caro and George E. Palade Protein Synthesis, Storage, and Discharge in the Pancreatic Exocrine Cell . . . . . . . . . . . . . . . . . . 473 Werner Straus Cytochemical Observations on the Relationship Between Lysosomes and Phagosomes in Kidney and Liver by Combined Staining for Acid Phosphatase and Intravenously Injected Horseradish Peroxidase . . . . . . . . . . . . . . . 497 N. Orzalesi and A. Bairati Filamentous Structures in the Inner Segment of Human Retinal Rods . . . . . 509 P. F. Millington Comparison of the Thicknesses of the Lateral Wall Membrane and the Microvillus Membrane of Intestinal Epithelial Cells from Rat and Mouse . . 514 J. D. McLean and S. J. Singer Cross-Linked Polyampholytes . . . . . . 518 B. R. A. O'Brien The Partial Cytolysis of the Amphibian Erythrocyte and Liver Parencyhma Cell by a Non-Ionogenic Surface Active Agent . . 521 B. R. A. O'Brien A Rapid Method for the Isolation and Collection of Nuclei from Whole Cell Suspensions . . . . . . . . . . . . . . 525 Peter K. Hepler and Eldon H. Newcomb Microtubules and Fibrils in the Cytoplasm of Coleus Cells Undergoing Secondary Wall Deposition . . . . . . . 529
Arthur M. Dannenberg and William E. Bennett Hydrolytic Enzymes of Rabbit Mononuclear Exudate Cells . . . . . . . . . . . . . 1 Janet A. Smith and Hector F. DeLuca Structural Changes in Isolated Liver Mitochondria of Rats During Essential Fatty Acid Deficiency . . . . . . . . . 15 T. M. Rizki and Rose M. Rizki Factors Affecting the Intracellualr Synthesis of Kynurenine . . . . . . . . 27 Joseph Osinchak Electron Microscopic Localization of Acid Phosphatase and Thiamine Pyrophosphatase Activity in Hypothalamic Neurosecretory Cells of the Rat . . . . 35 Elliott Robbins and Philip I. Marcus and Nicholas K. Gonatas Dynamics of Acridine Orange-Cell Interaction . . . . . . . . . . . . . . 49 Takashi Nakai A Study of the Ultrastructural Localization of Hair Keratin Synthesis Utilizing Electron Microscopic Autoradiography in a Magnetic Field . . 63 Jane Overton and Jane Shoup Fine Structure of Cell Surface Specializations in the Maturing Duodenal Mucosa of the Chick . . . . . . . . . . 75 E. G. Gray and J. Z. Young Electron Microscopy of Synaptic Structure of Octopus Brain . . . . . . . 87 Klaus Bensch and Gerald Gordon and Leonard Miller The Fate of DNA-Containing Particles Phagocytized by Mammalian Cells . . . . 105 Richard M. Eakin and Jane A. Westfall Fine Structure of the Eye of a Chaetognath . . . . . . . . . . . . . . 115 Velma C. Chambers and Russell S. Weiser Annulate Lamellae in Sarcoma I Cells . . 133 Donald A. Fischman and Michael D. Gershon A Method for Studying Intracellular Movement of Water-Soluble Isotopes Prior to Radioautography . . . . . . . . . . . 139 Marian Peterson and C. P. Leblond Synthesis of Complex Carbohydrates in the Golgi Region, As Shown by Radioautography After Injection of Labeled Glucose . . . . . . . . . . . . 143 Stanley Samuels and Nicholas K. Gonatas and Martin Weiss Chemical and Ultrastructural Comparison of Synthetic and Pathologic Membrane System . . . . . . . . . . . . . . . . . 148 C. E. Bracker and E. E. Butler Function of the Septal Pore Apparatus in Rhizoctonia Solani During Protoplasmic Streaming . . . . . . . . . . . . . . . 152
G. Marin and D. M. Prescott The Frequency of Sister Chromatid Exchanges Following Exposure to Varying Doses of H$^3$-Thymidine Or X-Rays . . . 159 Ivan L. Cameron and Günter Cleffmann Initiation of Mitosis in Relation to the Cell Cycle Following Feeding of Starved Chickens . . . . . . . . . . . . . . . . 169 Gunter F. Bahr and Elmar Zeitler Study of Bull Spermatozoa . . . . . . . 175 Seymour H. Wollman and Samuel S. Spicer and Marvin S. Burstone Localization of Esterase and Acid Phosphatase in Granules and Colloid Droplets in Rat Thyroid Epithelium . . . 191 T. M. Rizki Mutant Genes Regulating the Inducibility of Kynurenine Synthesis . . . . . . . . 203 V. G. Allfrey and V. C. Littau and A. E. Mirsky Methods for the Purification of Thymus Nuclei and Their Application to Studies of Nuclear Protein Synthesis . . . . . . 213 Nancy L. Trotter A Fine Structure Study of Lipid in Mouse Liver Regenerating After Partial Hepatectomy . . . . . . . . . . . . . . 233 K. W. Jones and T. R. Elsdale The Effects of Actinomycin D on the Ultrastructure of the Nucleus of the Amphibian Embryonic Cell . . . . . . . . 245 Thomas A. Shalla Assembly and Aggregation of Tobacco Mosaic Virus in Tomato Leaflets . . . . 253 M. E. Bayer An Electron Microscope Examination of Urinary Mucoprotein and Its Interaction with Influenza Virus . . . . . . . . . . 265 G. E. Stone and D. M. Prescott Cell Division and DNA Synthesis in \bionameTetrahymena Pyriformis Deprived of Essential Amino Acids . . . . . . . . 275 Luciano Ozzello Effects of 17-$ \beta $-estradiol and of growth hormone on the production of acid mucopolysaccharides by human embryonal fibroblasts in vitro . . . . . . . . . . 283 J. Herbert Taylor The Arrangement of Chromosomes in the Mature Sperm of the Grasshopper . . . . 286 Atsushi Suganuma The Plasma Membrane of \bionameStaphylococcus Aureus Treated with HCl Solutions . . . . . . . . . . . 290
Werner Straus Occurrence of Phagosomes and Phago-Lysosomes in Different Segments of the Nephron in Relation to the Reabsorption, Transport, Digestion, and Extrusion of Intravenously Injected Horseradish Peroxidase . . . . . . . . . 295 Herbert Schuel and Norman G. Anderson Studies on Isolated Cell Components . . 309 Robert M. Rosenbaum and Arnold Melman Cytochemical Differences in Kidneys from Winter-Hibernating and Aroused Bats (\bionameMyotis Lucifugus), with Particular Reference to the Golgi Zone 325 Nathan Lane and Lucien Caro and Luis R. Otero-Vilardebó and Gabriel C. Godman On the Site of Sulfation in Colonic Goblet Cells . . . . . . . . . . . . . . 339 Gabriel C. Godman and Nathan Lane On the Site of Sulfation in the Chondrocyte . . . . . . . . . . . . . . 353 Ewald R. Weibel and Bruce W. Knight A Morphometric Study on the Thickness of the Pulmonary Air-Blood Barrier . . . . 367 D. Gilmour and P. M. Robinson Contraction in Glycerinated Myofibrils of an Insect (Orthoptera, Acrididae) . . 385 Eleanor C. Adams and Arthur T. Hertig Studies on Guinea Pig Oocytes . . . . . 397 Elliott Robbins and Nicholas K. Gonatas The Ultrastructure of a Mammalian Cell During the Mitotic Cycle . . . . . . . . 429 Daniel Szollosi The Structure and Function of Centrioles and Their Satellites in the Jellyfish Phialidium Gregarium . . . . . . . . . . 465 Alan S. Cohen and Evan Calkins The Isolation of Amyloid Fibrils and a Study of the Effect of Collagenase and Hyaluronidase . . . . . . . . . . . . . 481 Luis R. Otero-Vilardebó and Nathan Lane and Gabriel C. Godman Localization of Phosphatase Activities in Colonic Goblet and Absorptive Cells 486 Albert I. Farbman Electron Microscope Study of a Small Cytoplasmic Structure in Rat Oral Epithelium . . . . . . . . . . . . . . . 491 R. F. Kimball and D. M. Prescott RNA and Protein Synthesis in Amacronucleate \bionameParamecium Aurelia . . . . . . . . . . . . . . . . 496
Werner H. Schreil Studies on the Fixation of Artificial and Bacterial DNA Plasms for the Electron Microscopy of Thin Sections . . 1 S. R. Pelc Labelling of DNA and Cell Division in So Called Non-Dividing Tissues . . . . . . 21 H. Dariush Fahimi and Chandra Raj Amarasingham Cytochemical Localization of Lactic Dehydrogenase in White Skeletal Muscle 29 John T. Stasny and F. L. Crane The Effect of Sonic Oscillation on the Structure and Function of Beef Heart Mitochondria . . . . . . . . . . . . . . 49 H. Fernández-Morán and T. Oda and P. V. Blair and D. E. Green A Macromolecular Repeating Unit of Mitochondrial Structure and Function . . 63 Harold Keiser and Gerald Weissmann and Alan W. Bernheimer Studies on Lysosomes . . . . . . . . . . 101 Gerald Weissmann and Beverly Becher and Lewis Thomas Studies on Lysosomes . . . . . . . . . . 115 Allen C. Enders and W. R. Lyons Observations on the Fine Structure of Lutein Cells . . . . . . . . . . . . . . 127 J. G. Lafontaine and C. Allard A Light and Electron Microscope Study of the Morphological Changes Induced in Rat Liver Cells by the Azo Dye $2$-Me-Dab 143 Albert W. Sedar and John G. Forte Effects of Calcium Depletion on the Junctional Complex Between Oxyntic Cells of Gastric Glands . . . . . . . . . . . 173 Filiberto Giacomelli and David Spiro and Joseph Wiener A Study of Metastatic Renal Calcification at the Cellular Level . . 189 Germaine Cohen-Bazire and Norbert Pfennig and Riyo Kunisawa The Fine Structure of Green Bacteria . . 207 Burton Goldberg and Howard Green An Analysis of Collagen Secretion by Established Mouse Fibroblast Lines . . . 227 Merrill K. Wolf Differentiation of Neuronal Types and Synapses in Myelinating Cultures of Mouse Cerebellum . . . . . . . . . . . . 259 Jacqueline Nonnenmacher-Godet and Ellsworth C. Dougherty Incorporation of Tritiated Thymidine in the Cells of \bionameCaenorhabditis Briggsae (Nematoda) Reared in Axenic Culture . . . . . . . . . . . . . . . . 281 John F. Jackson Chromosome Aberrations in Cultured Human Leukocytes Treated with $8$-Ethoxycaffeine . . . . . . . . . . . 291 Ramsey H. Frist and Morton D. Maser Freeze-Drying of Biological Specimens for Electron Microscopy Using Thermoelectric Cooling . . . . . . . . . 293 Beatríz G. T. Pogo and A. O. Pogo DNA Dependence of Plastid Differentiation Inhibition by Actinomycin D . . . . . . . . . . . . . 296 I. Ohad and D. Danon On the Dimensions of Cellulose Microfibrils . . . . . . . . . . . . . . 302
Peter Perlmann and Jane Couffer-Kaltenbach Antigens in Eggs and Developmental Stages of the Sea Urchin . . . . . . . . 307 Herbert Schuel and Samuel R. Tipton and Norman G. Anderson Studies on Isolated Cell Components . . 317 David P. Bloch and Sheilah D. Brack Evidence for the cytoplasmic synthesis of nuclear histone during spermiogenesis in the grasshopper \bionameChortophaga viridifasciata (de Geer) . . . . . . . . 327 Joseph Post and Joseph Hoffman The Replication Time and Pattern of Carcinogen-Induced Hepatoma Cells . . . 341 J. Ball and J. A. Chapman and K. D. Muirden The Uptake of Iron in Rabbit Synovial Tissue Following Intra-Articular Injection of Iron Dextran . . . . . . . 351 Russell Ross and Earl P. Benditt Wound Healing and Collagen Formation . . 365 Heinz Herrmann and N. W. Klein and G. Albers In Vitro Culture of Muscle Tissue from Normal, Heterozygous, and Dystrophic Chicks . . . . . . . . . . . . . . . . . 391 R. T. Sims The Incorporation and Fate of H$^3$-Tyrosine in the Hair Cortex of Rats Observed by Radioautography . . . . 403 Åke Flock Structure of the Macula Utriculi with Special Reference to Directional Interplay of Sensory Responses As Revealed by Morphological Polarization 413 Shimon Klein and G. Bryan and Lawrence Bogorad Early Stages in the Development of Plastid Fine Structure in Red and Far-Red Light . . . . . . . . . . . . . 433 Shimon Klein and Lawrence Bogorad Fine Structural Changes in Proplastids During Photodestruction of Pigments . . 443 Alexander Tomasz and James D. Jamieson and Elena Ottolenghi The Fine Structure of Diplococcus Pneumoniae . . . . . . . . . . . . . . . 453 M. M. Salpeter and L. Bachmann Autoradiography with the Electron Microscope . . . . . . . . . . . . . . . 469 Wolf H. Fahrenbach A New Configuration of the Sarcoplasmic Reticulum . . . . . . . . . . . . . . . 477 Rudolf Weber Ultrastructural Changes in Regressing Tail Muscles of \bionameXenopus Larvae at Metamorphosis . . . . . . . . . . . . 481 Lionel I. Rebhun and Thomas K. Sharpless Isolation of Spindles from the Surf Clam Spisula Solidissima . . . . . . . . . . 488
G. P. Studzinski and R. Love Effects of Puromycin on the Nucleoproteins of the HeLa Cell . . . . 493 D. R. Wolstenholme and W. Plaut Cytoplasmic DNA Synthesis in Amoeba Proteus . . . . . . . . . . . . . . . . 505 Sally B. Fand and Richard P. Spencer Off-Peak Absorption Measurements in Feulgen Cytophotometry . . . . . . . . . 515 Valerio Monesi Ribonucleic Acid Synthesis During Mitosis and Meiosis in the Mouse Testis 521 Winifred G. Nayler and Neil C. R. Merrillees Some Observations on the Fine Structure and Metabolic Activity of Normal and Glycerinated Ventricular Muscle of Toad 533 John Tooze Measurements of Some Cellular Changes During the Fixation of Amphibian Erythrocytes with Osmium Tetroxide Solutions . . . . . . . . . . . . . . . 551 Werner R. Loewenstein and Yoshinobu Kanno Studies on an Epithelial (Gland) Cell Junction . . . . . . . . . . . . . . . . 565 Joseph Wiener and David Spiro and Werner R. Loewenstein Studies on an Epithelial (Gland) Cell Junction . . . . . . . . . . . . . . . . 587 Richard A. Rifkind and David Danon and Paul A. Marks Alterations in Polyribosomes During Erythroid Cell Maturation . . . . . . . 599 William Perl Correction of Polyribosome Distributions As Observed in Cell Sections by Electron Microscopy . . . . . . . . . . . . . . . 613 Marvin L. Tanzer and Ronald D. Hunt Experimental Lathyrism . . . . . . . . . 623 O. Behnke and H. Moe An Electron Microscope Study of Mature and Differentiating Paneth Cells in the Rat, Especially of Their Endoplasmic Reticulum and Lysosomes . . . . . . . . 633 Douglas E. Kelly and Stuart W. Smith Fine Structure of the Pineal Organs of the Adult Frog, Rana Pipiens . . . . . . 653 Clara Franzini-armstrong and Keith R. Porter Sarcolemmal Invaginations Constituting the T System in Fish Muscle Fibers . . . 675 Jerome G. Stempak and Robert T. Ward An Improved Staining Method for Electron Microscopy . . . . . . . . . . . . . . . 697 J. D. McNabb and E. Sandborn Filaments in the Microvillous Border of Intestinal Cells . . . . . . . . . . . . 701 Robert A. Erlandson A new Maraglas, D.E.R.\reg 732, embedment for electron microscopy . . . 704 Jerome S. Kaye The Fine Structure of Flagella in Spermatids of the House Cricket . . . . 710 P. K. Thomas and H. Sheldon Tubular Arrays Derived from Myelin Breakdown During Wallerian Degeneration of Peripheral Nerve . . . . . . . . . . 715
William S. Lynn and Sydney Fortney and Rose H. Brown Osmotic and Metabolic Alterations of Mitochondrial Size . . . . . . . . . . . 1 William S. Lynn and Sydney Fortney and Rose H. Brown Role of EDTA and Metals in Mitochondrial Contraction . . . . . . . . . . . . . . 9 John W. Greenawalt and Carlo S. Rossi and Albert L. Lehninger Effect of Active Accumulation of Calcium and Phosphate Ions on the Structure of Rat Liver Mitochondria . . . . . . . . . 21 Sasha Koulish and Ruth G. Kleinfeld The Role of the Nucleolus . . . . . . . 39 T. C. Hsu Mammalian Chromosomes in Vitro . . . . . 53 James R. Coleman and Montrose J. Moses DNA and the Fine Structure of Synaptic Chromosomes in the Domestic Rooster (\bionameGallus Domesticus) . . . . . . 63 Edgar A. Tonna and Eugene P. Cronkite The Effects of Extraperiosteal Injections of Blood Components on Periosteal Cell Proliferation . . . . . 79 Ivan L. Cameron and Robert E. Smith Cytological Responses of Brown Fat Tissue in Cold-Exposed Rats . . . . . . 89 Ewald R. Weibel and George E. Palade New Cytoplasmic Components in Arterial Endothelia . . . . . . . . . . . . . . . 101 Richard S. Thomas Ultrastructural Localization of Mineral Matter in Bacterial Spores by Microincineration . . . . . . . . . . . 113 Patricia Barron Worden and W. R. Sistrom The Preparation and Properties of Bacterial Chromatophore Fractions . . . 135 J. D. Jamieson and G. E. Palade Specific Granules in Atrial Muscle Cells 151 Enrico Mugnaini Helical Filaments in Astrocytic Mitochondria of the Corpus Striatum in the Rat . . . . . . . . . . . . . . . . 173 Vivianne T. Nachmias Fibrillar Structures in the Cytoplasm of Chaos Chaos . . . . . . . . . . . . . . 183 Arya K. Bal and Paul R. Gross Suppression of Mitosis and Macromolecule Synthesis in Onion Roots by Heavy Water 188 Mathew J. Nadakavukaren Fine Structure of Negatively Stained Plant Mitochondria . . . . . . . . . . . 193 Edith Krugelis MacRae Organized Structures in the Nucleolus 195 H. Sheldon and J. M. McKenzie and D. Van Nimwegan Electron Microscopic Autoradiography . . 200
Mario H. Burgos and Agustin Aoki and Fabio L. Sacerdote Ultrastructure of Isolated Kidney Mitochondria Treated with Phlorizin and ATP . . . . . . . . . . . . . . . . . . 207 Morris J. Karnovsky The Localization of Cholinesterase Activity in Rat Cardiac Muscle by Electron Microscopy . . . . . . . . . . 217 Lichu Hsu and A. L. Tappel Lysosomal Enzymes of Rat Intestinal Mucosa . . . . . . . . . . . . . . . . . 233 Ethel Cosmos Intracellular Distribution of Calcium in Developing Breast Muscle of Normal and Dystrophic Chickens . . . . . . . . . . 241 Eugene Copeland A Mitochondrial Pump in the Cells of the Anal Papillae of Mosquito Larvae . . . . 253 Guy de-Thé Cytoplasmic Microtubules in Different Animal Cells . . . . . . . . . . . . . . 265 Robert M. Herndon The Fine Structure of the Rat Cerebellum 277 D. James Morré and Hilton H. Mollenhauer Isolation of the Golgi Apparatus from Plant Cells . . . . . . . . . . . . . . 295 Jack Rosenbluth and Steven L. Wissig The Distribution of Exogenous Ferritin in Toad Spinal Ganglia and the Mechanism of Its Uptake by Neurons . . . . . . . . 307 F. B. P. Wooding and D. H. Northcote The Development of the Secondary Wall of the Xylem in \bionameAcer Pseudoplatanus 327 Fernando L. Renaud and Hewson Swift The Development of Basal Bodies and Flagella in Allomyces Arbusculus . . . . 339 Mortimer Litt Studies in Experimental Eosinophilia . . 355 John F. Hartmann Cytochemical Localization of Adenosine Triphosphatase in the Mitotic Apparatus of HeLa and Sarcoma 180 Tissue Culture Cells . . . . . . . . . . . . . . . . . 363 Nancy Sype Simpson and Robert Gilmore McKinnell The Burnsi Gene As a Nuclear Marker for Transplantation Experiments in Frogs . . 371 P. K. Thomas The Deposition of Collagen in Relation to Schwann Cell Basement Membrane During Peripheral Nerve Regeneration . . . . . 375 Hisao Fujita and Mitsuo Machino Fine Structure of Intramitochondrial Crystals in Rat Thyroid Follicular Cell 383 Maimon M. Cohen and Margery W. Shaw Effects of Mitomycin C on Human Chromosomes . . . . . . . . . . . . . . 386 Robert E. Lee and Joseph D. Feldman Visualization of Antigenic Sites of Human Erythrocytes with Ferritin-Antibody Conjugates . . . . . . 396
Albert I. Lansing Age Variations in Cortical Membranes of Rotifers . . . . . . . . . . . . . . . . 403 C. C. Das and B. P. Kaufmann and Helen Gay Histone Protein Transition in \bionameDrosophila Melanogaster . . . . 423 S. R. Bawa Electron Microscope Study of Spermiogenesis in a Fire-Brat Insect, Thermobia Domestica Pack . . . . . . . . 431 Dorothy F. Travis and Melvin J. Glimcher The Structure and Organization Of, and the Relationship Between the Organic Matrix and the Inorganic Crystals of Embryonic Bovine Enamel . . . . . . . . 447 M. Weintraub and H. W. J. Ragetli An Electron Microscope Study of Tobacco Mosaic Virus Lesions in \bionameNicotiana Glutinosa L . . . . . 499 Susumu Kishimoto and Irving Lieberman A Nuclear Membrane Change After Partial Hepatectomy . . . . . . . . . . . . . . 511 Fritz Miller and George E. Palade Lytic Activities in Renal Protein Absorption Droplets . . . . . . . . . . 519 M. M. Dewey and L. Barr A Study of the Structure and Distribution of the Nexus . . . . . . . 553 Jeanne L. Stove Poindexter and Germaine Cohen-Bazire The Fine Structure of Stalked Bacteria Belonging to the Family Caulobacteraceae 587 Jane Baxandall and P. Perlmann and B. A. Afzelius Immuno-Electron Microscope Analysis of the Surface Layers of the Unfertilised Sea Urchin Egg . . . . . . . . . . . . . 609 Jane Baxandall and P. Perlmann and B. A. Afzelius Immuno-Electron Microscope Analysis of the Surface Layers of the Unfertilised Sea Urchin Egg . . . . . . . . . . . . . 629 Arnold J. Petersen DNA Synthesis and Chromosomal Asynchrony 651 O. L. Miller and G. E. Stone and D. M. Prescott Autoradiography of Soluble Materials . . 654 John McD. Tormey Differences in Membrane Configuration Between Osmium Tetroxide-Fixed and Glutaraldehyde-Fixed Ciliary Epithelium 658 N. J. Berrill and H. Sheldon The Fine Structure of the Connections Between Muscle Cells in Ascidian Tadpole Larva . . . . . . . . . . . . . . . . . 664 William A. Jensen Observations on the Fusion of Nuclei in Plants . . . . . . . . . . . . . . . . . 669